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Showing 25 to 36 of 277 entries
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Computational design of a synthetic PD-1 agonist.

Proceedings of the National Academy of Sciences of the United States of America

Bryan CM, Rocklin GJ, Bick MJ, Ford A, Majri-Morrison S, Kroll AV, Miller CJ, Carter L, Goreshnik I, Kang A, DiMaio F, Tarbell KV, Baker D.
PMID: 34272285
Proc Natl Acad Sci U S A. 2021 Jul 20;118(29). doi: 10.1073/pnas.2102164118.

Programmed cell death protein-1 (PD-1) expressed on activated T cells inhibits T cell function and proliferation to prevent an excessive immune response, and disease can result if this delicate balance is shifted in either direction. Tumor cells often take...

Study on augmented reality for robotic surgery bedside assistants.

Journal of robotic surgery

Stewart CL, Fong A, Payyavula G, DiMaio S, Lafaro K, Tallmon K, Wren S, Sorger J, Fong Y.
PMID: 34762249
J Robot Surg. 2021 Nov 11; doi: 10.1007/s11701-021-01335-z. Epub 2021 Nov 11.

Robotic surgery bedside assistants play an important role in robotic procedures by performing intra-corporeal tasks while accommodating the physical presence of the robot. We hypothesized that an augmented reality headset enabling 3D intra-corporeal vision while facing the surgical field...

Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar.

PLoS neglected tropical diseases

Lieberman NAP, Lin MJ, Xie H, Shrestha L, Nguyen T, Huang ML, Haynes AM, Romeis E, Wang QQ, Zhang RL, Kou CX, Ciccarese G, Dal Conte I, Cusini M, Drago F, Nakayama SI, Lee K, Ohnishi M, Konda KA, Vargas SK, Eguiluz M, Caceres CF, Klausner JD, Mitjà O, Rompalo A, Mulcahy F, Hook EW, Lukehart SA, Casto AM, Roychoudhury P, DiMaio F, Giacani L, Greninger AL.
PMID: 34936652
PLoS Negl Trop Dis. 2021 Dec 22;15(12):e0010063. doi: 10.1371/journal.pntd.0010063. eCollection 2021 Dec.

In spite of its immutable susceptibility to penicillin, Treponema pallidum (T. pallidum) subsp. pallidum continues to cause millions of cases of syphilis each year worldwide, resulting in significant morbidity and mortality and underscoring the urgency of developing an effective...

Machine learning analysis of multispectral imaging and clinical risk factors to predict amputation wound healing.

Journal of vascular surgery

Squiers JJ, Thatcher JE, Bastawros DS, Applewhite AJ, Baxter RD, Yi F, Quan P, Yu S, DiMaio JM, Gable DR.
PMID: 34314834
J Vasc Surg. 2022 Jan;75(1):279-285. doi: 10.1016/j.jvs.2021.06.478. Epub 2021 Jul 24.

OBJECTIVE: Prediction of amputation wound healing is challenging due to the multifactorial nature of critical limb ischemia and lack of objective assessment tools. Up to one-third of amputations require revision to a more proximal level within 1 year. We...

Correction: Lumen-apposing stents versus plastic stents in the management of pancreatic pseudocysts: a large, comparative, international, multicenter study.

Endoscopy

Yang J, Chen YI, Friedland S, Holmes I, Paiji C, Law R, Hosmer A, Stevens T, Matheus F, Pawa R, Mathur N, Sejpal D, Inamdar S, Berzin TM, DiMaio CJ, Gupta S, Yachimski PS, Anderloni A, Repici A, James T, Jamil LH, Ona M, Lo SK, Gaddam S, Dollhopf M, Alammar N, Shieh E, Bukhari M, Kumbhari V, Singh V, Brewer O, Sanaei O, Fayad L, Ngamruengphong S, Shin EJ, Baron TH, Khashab MA.
PMID: 30769348
Endoscopy. 2019 Nov;51(11):C5. doi: 10.1055/a-0852-9243. Epub 2019 Feb 15.

No abstract available.

Impact of Blinding on Patient-Reported Outcome Differences between Treatment Arms in Cancer Randomized Controlled Trials.

Journal of the National Cancer Institute

Efficace F, Cella D, Aaronson NK, Calvert M, Cottone F, Di Maio M, Perrone F, Sparano F, Gamper EM, Vignetti M, Giesinger JM.
PMID: 34508610
J Natl Cancer Inst. 2021 Sep 11; doi: 10.1093/jnci/djab177. Epub 2021 Sep 11.

Some concerns have been raised about potential bias in patient-reported outcome (PRO) results from open-label cancer randomized controlled trials (RCTs). We investigated if open-label trials favor the experimental treatment over the standard treatment more frequently than blinded trials. We...

Equity in Drug Accessibility: The Surprising Case of Treatments for Metastatic Castration-sensitive Prostate Cancer in European Countries.

European urology oncology

Caffo O, Di Maio M.
PMID: 34535420
Eur Urol Oncol. 2021 Dec;4(6):1011-1012. doi: 10.1016/j.euo.2021.08.002. Epub 2021 Sep 15.

No abstract available.

Two Cases of Cutaneous Nocardiosis After a Natural Disaster.

Cureus

Al-Obaydi S, DeMaio J.
PMID: 31911871
Cureus. 2019 Dec 02;11(12):e6278. doi: 10.7759/cureus.6278.

Skin and soft tissue infections have been well-documented after natural disasters; however, to the best of our knowledge, Nocardia brasiliensis (N. brasiliensis) is not included in the Centers for Disease Control and Prevention (CDC) list of environmental pathogens associated...

Long-term outcomes of the Ross procedure in adults.

Annals of cardiothoracic surgery

Ryan WH, Squiers JJ, Harrington KB, Goodenow T, Rawitscher C, Schaffer JM, DiMaio JM, Brinkman WT.
PMID: 34422562
Ann Cardiothorac Surg. 2021 Jul;10(4):499-508. doi: 10.21037/acs-2021-rp-fs-28.

BACKGROUND: The optimal aortic valve replacement for young and middle-aged adults remains elusive. Although several high-volume international centers and surgeons have demonstrated excellent long-term results with the pulmonary autograft (Ross procedure) in adult patients, current guidelines from the United...

A review of guidelines for lung cancer.

Journal of thoracic disease

Bironzo P, Di Maio M.
PMID: 29951306
J Thorac Dis. 2018 May;10:S1556-S1563. doi: 10.21037/jtd.2018.03.54.

Clinical practice guidelines include recommendations intended to optimize patient care. In the last years, the introduction of immune checkpoint inhibitors is rapidly changing lung cancer management and therefore guidelines are essential to assist clinicians in such an evolving field....

Left Atrial Volume during Stress Is Associated with Increased Risk of Arrhythmias in Patients with Hypertrophic Cardiomyopathy.

Journal of cardiovascular echography

Limongelli G, Fioretti V, Di Maio M, Verrengia M, Rubino M, Gravino R, Masarone D, D'Andrea A, Ciampi Q, Picano E, Elliott P, Pacileo G.
PMID: 31008030
J Cardiovasc Echogr. 2019 Jan-Mar;29(1):1-6. doi: 10.4103/jcecho.jcecho_45_18.

INTRODUCTION: In patients affected by hypertrophic cardiomyopathy (HCM), left atrial volume index (LAVi) is associated with an increased risk of tachyarrhythmias and major clinical events. To date, the clinical meaning of LAVi measured during exercise (stress LAVi [sLAVi]) has...

High Prevalence of Proarrhythmic Events in Patients With History of Atrial Fibrillation Undergoing a Rhythm Control Strategy: A Retrospective Study.

Journal of clinical medicine research

De Vecchis R, Di Maio M, Noutsias M, Rigopoulos AG, Ariano C, Di Biase G.
PMID: 31019629
J Clin Med Res. 2019 May;11(5):345-352. doi: 10.14740/jocmr3805. Epub 2019 Apr 14.

BACKGROUND: A retrospective study was undertaken to evaluate the respective prevalence of proarrhythmic events depending on various therapeutic regimens within a population of patients with history of atrial fibrillation (AF) undergoing a rhythm control strategy.METHODS: Inclusion criterion was the...

Showing 25 to 36 of 277 entries