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Showing 3217 to 3228 of 3228 entries
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MicroRNA-133b-3p Targets Purinergic P2X4 Receptor to Regulate Central Poststroke Pain in Rats.

Neuroscience

Guo X, Lu J, Yan M, Wang Y, Yang Y, Li H, Shen H, Diao S, Ni J, Lu H, Zhao H, Chen G.
PMID: 34688806
Neuroscience. 2021 Oct 21;481:60-72. doi: 10.1016/j.neuroscience.2021.10.015. Epub 2021 Oct 21.

Central poststroke pain (CPSP) is a neuropathic pain syndrome that usually occurs after cerebrovascular accidents. Currently, the pathogenesis of CPSP is not fully understood. Purinergic P2X4 receptor (P2X4R) is implicated in neuropathic pain including CPSP. Herein, we demonstrated that...

Functionalized PDA/DEX-PEI@HA nanoparticles combined with sleeping-beauty transposons for multistage targeted delivery of CRISPR/Cas9 gene.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Ma K, Li W, Zhu G, Sun S, Chi H, Yin Y, Diao H, Xing XJ, Guo Z, Wang L, Xu W, Cui C, Xu J.
PMID: 34449313
Biomed Pharmacother. 2021 Oct;142:112061. doi: 10.1016/j.biopha.2021.112061. Epub 2021 Aug 24.

CRISPR/Cas9 system has been used as the most powerful gene editing tool for precision medicine and advanced gene therapy. However, its wide applications are limited by the poor biosafety of lentivirus delivery vectors though with high-efficiency transduction. To construct...

Liver Involvement by Perforated Peptic Ulcer: A Systematic Review.

Journal of clinical and translational pathology

Jiao J, Zhang L.
PMID: 34927172
J Clin Transl Pathol. 2021;1(1):2-8. doi: 10.14218/jctp.2021.00007. Epub 2021 Jun 04.

BACKGROUND AND OBJECTIVE: Liver penetration by a confined perforation of peptic ulcer is a rare but severe event. Its clinical and pathological features are unclear.METHODS: In total, 41 qualified English publications were identified using the PubMed database and one...

A Polyoxometalate-Based Inorganic Porous Material with both Proton and Electron Conductivity by Light Actuation: Photocatalysis for Baeyer-Villiger Oxidation and Cr(VI) Reduction.

Inorganic chemistry

Si C, Ma P, Han Q, Jiao J, Du W, Wu J, Li M, Niu J.
PMID: 33355447
Inorg Chem. 2021 Jan 18;60(2):682-691. doi: 10.1021/acs.inorgchem.0c02658. Epub 2020 Dec 23.

Two-dimensional (2D) crystalline porous materials with designable structures and high surface areas are currently a hot research topic in the field of proton- and electron-conducting materials, which provide great opportunities to orderly accommodate carriers in available spaces and to...

Association between initial opioid prescription diagnosis type and subsequent chronic prescription opioid use in Rhode Island: a population-based cohort study.

BMJ open

Hallowell BD, Chambers LC, Barre L, Diao N, Onyejekwe C, Banks A, Bratberg J, Weidele H, Viner-Brown S, McDonald J.
PMID: 34992104
BMJ Open. 2022 Jan 06;12(1):e050540. doi: 10.1136/bmjopen-2021-050540.

OBJECTIVE: To identify initial diagnoses associated with elevated risk of chronic prescription opioid use.DESIGN: Population-based, retrospective cohort study.SETTING: State of Rhode Island.PARTICIPANTS: Rhode Island residents with an initial opioid prescription dispensed between 1 April 2019 and 31 March 2020.PRIMARY...

Evaluation of Ride Comfort in a Railway Passenger Car Depending on a Change of Suspension Parameters.

Sensors (Basel, Switzerland)

Dižo J, Blatnický M, Gerlici J, Leitner B, Melnik R, Semenov S, Mikhailov E, Kostrzewski M.
PMID: 34884142
Sensors (Basel). 2021 Dec 06;21(23). doi: 10.3390/s21238138.

Ride comfort for passengers remains a pressing topic. The level of comfort in a vehicle can influences passengers' preferences for a particular means of transport. The article aims to evaluate the influence of changes in suspension parameters on the...

Dictionary Learning-Based Ultrasound Image Combined with Gastroscope for Diagnosis of Helicobacter pylori-Caused Gastrointestinal Bleeding.

Computational and mathematical methods in medicine

Diao Y, Zhang Z.
PMID: 34992675
Comput Math Methods Med. 2021 Dec 28;2021:6598631. doi: 10.1155/2021/6598631. eCollection 2021.

The study is aimed at evaluating the application value of ultrasound combined with gastroscopy in diagnosing gastrointestinal bleeding (GIB) caused by Helicobacter pylori (HP). An ultrasound combined with a gastroscopy diagnostic model based on improved

Quantitative assessment of multiple pesticides in silicone wristbands of children/guardian pairs living in agricultural areas in South Africa.

The Science of the total environment

Fuhrimann S, Mol HGJ, Dias J, Dalvie MA, Röösli M, Degrendele C, Figueiredo DM, Huss A, Portengen L, Vermeulen R.
PMID: 34906574
Sci Total Environ. 2021 Dec 11;812:152330. doi: 10.1016/j.scitotenv.2021.152330. Epub 2021 Dec 11.

Little is known about personal and time-integrated exposure to past and current used pesticides in agricultural areas and within-family exposure similarities. We aimed to assess exposure to pesticides using silicone wristbands in child/guardian pairs living on farms and in...

Target Characterization of Kaempferol against Myocardial Infarction Using Novel In Silico Docking and DARTS Prediction Strategy.

International journal of molecular sciences

Wu X, Li X, Yang C, Diao Y.
PMID: 34884711
Int J Mol Sci. 2021 Nov 29;22(23). doi: 10.3390/ijms222312908.

Target identification is a crucial process for advancing natural products and drug leads development, which is often the most challenging and time-consuming step. However, the putative biological targets of natural products obtained from traditional prediction studies are also informatively...

Exploring Microbial Resource of Different Rhizocompartments of Dominant Plants Along the Salinity Gradient Around the Hypersaline Lake Ejinur.

Frontiers in microbiology

Luo J, Zhang Z, Hou Y, Diao F, Hao B, Bao Z, Wang L, Guo W.
PMID: 34322109
Front Microbiol. 2021 Jul 12;12:698479. doi: 10.3389/fmicb.2021.698479. eCollection 2021.

Lake littoral zones can also be regarded as another extremely hypersaline environment due to hypersaline properties of salt lakes. In this study, high-throughput sequencing technique was used to analyze bacteria and fungi from different rhizocompartments (rhizosphere and endosphere) of...

Psychometric Analysis of the Dating Anxiety Scale for Adolescents in Samples of Polish and U.S. Young Adults: Examining the Factor Structure, Measurement Invariance, Item Functioning, and Convergent Validity.

Assessment

Adamczyk K, Morelli NM, Segrin C, Jiao J, Park JY, Villodas MT.
PMID: 34350808
Assessment. 2021 Aug 05;10731911211017659. doi: 10.1177/10731911211017659. Epub 2021 Aug 05.

This study explored whether the Dating Anxiety Scale for Adolescents (DAS-A), which was originally developed in the United States to assess dating anxiety in adolescents, is appropriate for use in samples of young adults from Poland and the United...

Bis-triazole-containing Compounds with Anticancer Potential: A Short Review.

Current topics in medicinal chemistry

Gao M, Diao Q, Gao F, Sun X, Xiao J.
PMID: 34323190
Curr Top Med Chem. 2021;21(18):1674-1691. doi: 10.2174/1568026621666210728154728.

The development of novel anticancer agents with high efficiency is of great importance due to the severe anticancer scenario of the currently used drugs. Dimerization is a useful method to develop new drug candidates with a broad biological spectrum,...

Showing 3217 to 3228 of 3228 entries