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Showing 25 to 36 of 270 entries
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The quality of life: design and evaluation of a self-assessment instrument for use with cancer patients.

International journal of nursing studies

Holmes S, Dickerson J.
PMID: 3644797
Int J Nurs Stud. 1987;24(1):15-24. doi: 10.1016/0020-7489(87)90035-6.

An attempt was made to define the concept of 'quality of life' and outline the development of a self-assessment instrument for detecting the changes in life as a whole which result from the presence and treatment of malignant disease....

CytoModeler: a tool for bridging large-scale network analysis and dynamic quantitative modeling.

Bioinformatics (Oxford, England)

Xia T, Van Hemert J, Dickerson JA.
PMID: 21511714
Bioinformatics. 2011 Jun 01;27(11):1578-80. doi: 10.1093/bioinformatics/btr150. Epub 2011 Apr 20.

SUMMARY: CytoModeler is an open-source Java application based on the Cytoscape platform. It integrates large-scale network analysis and quantitative modeling by combining omics analysis on the Cytoscape platform, access to deterministic and stochastic simulators, and static and dynamic network...

Discovery of the First Selective M.

ACS pharmacology & translational science

Moehle MS, Bender AM, Dickerson JW, Foster DJ, Qi A, Cho HP, Donsante Y, Peng W, Bryant Z, Stillwell KJ, Bridges TM, Chang S, Watson KJ, O'Neill JC, Engers JL, Peng L, Rodriguez AL, Niswender CM, Lindsley CW, Hess EJ, Conn PJ, Rook JM.
PMID: 34423268
ACS Pharmacol Transl Sci. 2021 Aug 02;4(4):1306-1321. doi: 10.1021/acsptsci.0c00162. eCollection 2021 Aug 13.

Nonselective antagonists of muscarinic acetylcholine receptors (mAChRs) that broadly inhibit all five mAChR subtypes provide an efficacious treatment for some movement disorders, including Parkinson's disease and dystonia. Despite their efficacy in these and other central nervous system disorders, antimuscarinic...

Neural substrates of verbal repetition deficits in primary progressive aphasia.

Brain communications

Miller HE, Cordella C, Collins JA, Ezzo R, Quimby M, Hochberg D, Tourville JA, Dickerson BC, Guenther FH.
PMID: 33748756
Brain Commun. 2021 Feb 16;3(1):fcab015. doi: 10.1093/braincomms/fcab015. eCollection 2021.

In this cross-sectional study, we examined the relationship between cortical thickness and performance on several verbal repetition tasks in a cohort of patients with primary progressive aphasia in order to test predictions generated by theoretical accounts of phonological working...

Advances in neuroimaging to support translational medicine in dementia.

Journal of neurology, neurosurgery, and psychiatry

Cope TE, Weil RS, Düzel E, Dickerson BC, Rowe JB.
PMID: 33568448
J Neurol Neurosurg Psychiatry. 2021 Mar;92(3):263-270. doi: 10.1136/jnnp-2019-322402. Epub 2021 Feb 10.

Advances in neuroimaging are ideally placed to facilitate the translation from progress made in cellular genetics and molecular biology of neurodegeneration into improved diagnosis, prevention and treatment of dementia. New positron emission tomography (PET) ligands allow one to quantify...

Synthesis and characterization of chiral 6-azaspiro[2.5]octanes as potent and selective antagonists of the M.

Bioorganic & medicinal chemistry letters

Bender AM, Carter TR, Spock M, Rodriguez AL, Dickerson JW, Rook JM, Chang S, Qi A, Presley CC, Engers DW, Harp JM, Bridges TM, Niswender CM, Conn PJ, Lindsley CW.
PMID: 34838649
Bioorg Med Chem Lett. 2021 Nov 24;56:128479. doi: 10.1016/j.bmcl.2021.128479. Epub 2021 Nov 24.

In this manuscript, we report a series of chiral 6-azaspiro[2.5]octanes and related spirocycles as highly potent and selective antagonists of the muscarinic acetylcholine receptor subtype 4 (mAChR

Influence of landscape condition on relative abundance and body condition of two generalist freshwater turtle species.

Ecology and evolution

Mota JL, Brown DJ, Canning DM, Crayton SM, Lozon DN, Gulette AL, Anderson JT, Mali I, Dickerson BE, Forstner MRJ, Watson MB, Pauley TK.
PMID: 34026025
Ecol Evol. 2021 Mar 24;11(10):5511-5521. doi: 10.1002/ece3.7450. eCollection 2021 May.

Anthropogenic land use changes have broad impacts on biological diversity, often resulting in shifts in community composition. While many studies have documented negative impacts on occurrence and abundance of species, less attention has been given to native species that...

Mindfulness Training Improves Cognition and Strengthens Intrinsic Connectivity Between the Hippocampus and Posteromedial Cortex in Healthy Older Adults.

Frontiers in aging neuroscience

Sevinc G, Rusche J, Wong B, Datta T, Kaufman R, Gutz SE, Schneider M, Todorova N, Gaser C, Thomalla G, Rentz D, Dickerson BD, Lazar SW.
PMID: 34512305
Front Aging Neurosci. 2021 Aug 27;13:702796. doi: 10.3389/fnagi.2021.702796. eCollection 2021.

Maintaining optimal cognitive functioning throughout the lifespan is a public health priority. Evaluation of cognitive outcomes following interventions to promote and preserve brain structure and function in older adults, and associated neural mechanisms, are therefore of critical importance. In...

Surface chemical trapping of optical cycling centers.

Physical chemistry chemical physics : PCCP

Guo H, Dickerson CE, Shin AJ, Zhao C, Atallah TL, Caram JR, Campbell WC, Alexandrova AN.
PMID: 33325472
Phys Chem Chem Phys. 2021 Jan 06;23(1):211-218. doi: 10.1039/d0cp04525j.

Quantum information processors based on trapped atoms utilize laser-induced optical cycling transitions for state preparation and measurement. These transitions consist of an electronic excitation from the ground to an excited state and a decay back to the initial ground...

Psychosocial Stressors and Adaptive Coping Strategies in Couples After a Diagnosis of Young-Onset Dementia.

The Gerontologist

Bannon S, Reichman M, Popok P, Grunberg VA, Traeger L, Gates M, Krahn EA, Brandt K, Quimby M, Wong B, Dickerson BC, Vranceanu AM.
PMID: 33893481
Gerontologist. 2021 Apr 19; doi: 10.1093/geront/gnab053. Epub 2021 Apr 19.

BACKGROUND AND OBJECTIVES: Diagnoses of young-onset dementias (YOD) are devastating for persons with dementia and spousal caregivers yet limited work has examined both partners' perceptions of challenges and coping after diagnosis. This qualitative study investigated the psychosocial stressors and...

Eliminating Cross-Connections Between Raw and Pasteurized Products in Dairy Plants.

Journal of food protection

Dickerson RW.
PMID: 30978818
J Food Prot. 1987 Nov;50(11):964-967. doi: 10.4315/0362-028X-50.11.964.

A method was developed to identify cross-connections between raw and pasteurized products in dairy plants. A flow diagram of the dairy plant is used to identify post-pasteurization pumps, storage tanks, fillers or other post-pasteurization processing equipment. An envelope is...

A race against time: couples' lived diagnostic journeys to young-onset dementia.

Aging & mental health

Grunberg VA, Bannon SM, Popok P, Reichman M, Dickerson BC, Vranceanu AM.
PMID: 34435534
Aging Ment Health. 2021 Aug 26;1-10. doi: 10.1080/13607863.2021.1966748. Epub 2021 Aug 26.

PURPOSE: Young onset dementias (YOD) - typically defined by symptom onset before age 65 - are frequently overlooked in medical and community settings. Persons with YOD and their spouses face logistical and emotional challenges on their journey to a...

Showing 25 to 36 of 270 entries