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Showing 145 to 148 of 148 entries
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Elucidating the molecular mechanisms associated with TARS2-related mitochondrial disease.

Human molecular genetics

Zheng WQ, Pedersen SV, Thompson K, Bellacchio E, French CE, Munro B, Pearson TS, Vogt J, Diodato D, Diemer T, Ernst A, Horvath R, Chitre M, Ek J, Wibrand F, Grange DK, Raymond L, Zhou XL, Taylor RW, Ostergaard E.
PMID: 34508595
Hum Mol Genet. 2021 Sep 11; doi: 10.1093/hmg/ddab257. Epub 2021 Sep 11.

TARS2 encodes human mitochondrial threonyl tRNA-synthetase that is responsible for generating mitochondrial Thr-tRNAThr and clearing mischarged Ser-tRNAThr during mitochondrial translation. Pathogenic variants in TARS2 have hitherto been reported in a pair of siblings and an unrelated patient with an...

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Zheng WQ, Pedersen SV, Thompson K, et al. Elucidating the molecular mechanisms associated with TARS2-related mitochondrial disease. Hum Mol Genet. 2021;doi: 10.1093/hmg/ddab257.
Zheng, W. Q., Pedersen, S. V., Thompson, K., Bellacchio, E., French, C. E., Munro, B., Pearson, T. S., Vogt, J., Diodato, D., Diemer, T., Ernst, A., Horvath, R., Chitre, M., Ek, J., Wibrand, F., Grange, D. K., Raymond, L., Zhou, X. L., Taylor, R. W., & Ostergaard, E. (2021). Elucidating the molecular mechanisms associated with TARS2-related mitochondrial disease. Human molecular genetics, . https://doi.org/10.1093/hmg/ddab257
Zheng, Wen-Qiang, et al. "Elucidating the molecular mechanisms associated with TARS2-related mitochondrial disease." Human molecular genetics vol. (2021). doi: https://doi.org/10.1093/hmg/ddab257
Zheng WQ, Pedersen SV, Thompson K, Bellacchio E, French CE, Munro B, Pearson TS, Vogt J, Diodato D, Diemer T, Ernst A, Horvath R, Chitre M, Ek J, Wibrand F, Grange DK, Raymond L, Zhou XL, Taylor RW, Ostergaard E. Elucidating the molecular mechanisms associated with TARS2-related mitochondrial disease. Hum Mol Genet. 2021 Sep 11; doi: 10.1093/hmg/ddab257. Epub 2021 Sep 11. PMID: 34508595.
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High-Resolution IMS-MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody.

Journal of the American Society for Mass Spectrometry

Deslignière E, Botzanowski T, Diemer H, Cooper-Shepherd DA, Wagner-Rousset E, Colas O, Béchade G, Giles K, Hernandez-Alba O, Beck A, Cianférani S.
PMID: 34437803
J Am Soc Mass Spectrom. 2021 Oct 06;32(10):2505-2512. doi: 10.1021/jasms.1c00151. Epub 2021 Aug 26.

Monoclonal antibodies (mAbs) have taken on an increasing importance for the treatment of various diseases, including cancers and immunological disorders. Disulfide bonds play a pivotal role in therapeutic antibody structure and activity relationships. Disulfide connectivity and cysteine-related variants are...

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Deslignière E, Botzanowski T, Diemer H, et al. High-Resolution IMS-MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody. J Am Soc Mass Spectrom. 2021;32(10):2505-2512doi: 10.1021/jasms.1c00151.
Deslignière, E., Botzanowski, T., Diemer, H., Cooper-Shepherd, D. A., Wagner-Rousset, E., Colas, O., Béchade, G., Giles, K., Hernandez-Alba, O., Beck, A., & Cianférani, S. (2021). High-Resolution IMS-MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody. Journal of the American Society for Mass Spectrometry, 32(10), 2505-2512. https://doi.org/10.1021/jasms.1c00151
Deslignière, Evolène, et al. "High-Resolution IMS-MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody." Journal of the American Society for Mass Spectrometry vol. 32,10 (2021): 2505-2512. doi: https://doi.org/10.1021/jasms.1c00151
Deslignière E, Botzanowski T, Diemer H, Cooper-Shepherd DA, Wagner-Rousset E, Colas O, Béchade G, Giles K, Hernandez-Alba O, Beck A, Cianférani S. High-Resolution IMS-MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody. J Am Soc Mass Spectrom. 2021 Oct 06;32(10):2505-2512. doi: 10.1021/jasms.1c00151. Epub 2021 Aug 26. PMID: 34437803.
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Author Response to "Concerns About the Methodology and Data Collection in a Systematic Review".

The Journal of orthopaedic and sports physical therapy

Saueressig T, Diemer F, Zebisch J, Owen PJ, Belavy DL.
PMID: 34972485
J Orthop Sports Phys Ther. 2022 Jan;52(1):50-51. doi: 10.2519/jospt.2022.0201-R.

Author response to the

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Saueressig T, Diemer F, Zebisch J, et al. Author Response to "Concerns About the Methodology and Data Collection in a Systematic Review". J Orthop Sports Phys Ther. 2022;52(1):50-51doi: 10.2519/jospt.2022.0201-R.
Saueressig, T., Diemer, F., Zebisch, J., Owen, P. J., & Belavy, D. L. (2022). Author Response to "Concerns About the Methodology and Data Collection in a Systematic Review". The Journal of orthopaedic and sports physical therapy, 52(1), 50-51. https://doi.org/10.2519/jospt.2022.0201-R
Saueressig, Tobias, et al. "Author Response to "Concerns About the Methodology and Data Collection in a Systematic Review"." The Journal of orthopaedic and sports physical therapy vol. 52,1 (2022): 50-51. doi: https://doi.org/10.2519/jospt.2022.0201-R
Saueressig T, Diemer F, Zebisch J, Owen PJ, Belavy DL. Author Response to "Concerns About the Methodology and Data Collection in a Systematic Review". J Orthop Sports Phys Ther. 2022 Jan;52(1):50-51. doi: 10.2519/jospt.2022.0201-R. PMID: 34972485.
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LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy.

EMBO molecular medicine

Li P, Li Q, Biswas N, Xin H, Diemer T, Liu L, Perez Gutierrez L, Paternostro G, Piermarocchi C, Domanskyi S, Wang RK, Ferrara N.
PMID: 34779136
EMBO Mol Med. 2022 Jan 11;14(1):e14511. doi: 10.15252/emmm.202114511. Epub 2021 Nov 15.

In the course of our studies aiming to discover vascular bed-specific endothelial cell (EC) mitogens, we identified leukemia inhibitory factor (LIF) as a mitogen for bovine choroidal EC (BCE), although LIF has been mainly characterized as an EC growth...

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Li P, Li Q, Biswas N, et al. LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy. EMBO Mol Med. 2021;14(1):e14511doi: 10.15252/emmm.202114511.
Li, P., Li, Q., Biswas, N., Xin, H., Diemer, T., Liu, L., Perez Gutierrez, L., Paternostro, G., Piermarocchi, C., Domanskyi, S., Wang, R. K., & Ferrara, N. (2022). LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy. EMBO molecular medicine, 14(1), e14511. https://doi.org/10.15252/emmm.202114511
Li, Pin, et al. "LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy." EMBO molecular medicine vol. 14,1 (2022): e14511. doi: https://doi.org/10.15252/emmm.202114511
Li P, Li Q, Biswas N, Xin H, Diemer T, Liu L, Perez Gutierrez L, Paternostro G, Piermarocchi C, Domanskyi S, Wang RK, Ferrara N. LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy. EMBO Mol Med. 2022 Jan 11;14(1):e14511. doi: 10.15252/emmm.202114511. Epub 2021 Nov 15. PMID: 34779136; PMCID: PMC8749470.
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Showing 145 to 148 of 148 entries