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Showing 37 to 38 of 38 entries
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Platelet phagocytosis via PSGL1 and accumulation of microparticles in systemic sclerosis.

Arthritis & rheumatology (Hoboken, N.J.)

Manfredi AA, Ramirez GA, Godino C, Capobianco A, Monno A, Franchini S, Tombetti E, Corradetti S, Distler JH, Bianchi ME, Rovere-Querini P, Maugeri N.
PMID: 34279048
Arthritis Rheumatol. 2021 Jul 19; doi: 10.1002/art.41926. Epub 2021 Jul 19.

OBJECTIVES: It is unclear why activated platelets and platelet-derived microparticles (µPs) accumulate in the blood of patients with systemic sclerosis (SSc). Here we investigated whether defective phagocytosis might contribute.METHODS: Platelet-neutrophil interaction, phagocytosis, P-selectin, PSGL-1, HMGB1 expression and distribution on...

Estimated glomerular filtration rate is a marker of mortality in the European Scleroderma Trials and Research Group (EUSTAR) database.

Rheumatology (Oxford, England)

Gigante A, Hoffmann-Vold AM, Fegatelli DA, Gabrielli A, Leodori G, Coleiro B, De Santis M, Dagna L, Alegre-Sancho JJ, Montecucco C, Carreira PE, Balbir-Gurman A, Doria A, Riemekasten G, Airò P, Distler J, Distler O, Rosato E.
PMID: 33769468
Rheumatology (Oxford). 2021 Mar 26; doi: 10.1093/rheumatology/keab302. Epub 2021 Mar 26.

OBJECTIVES: Study aim was to evaluate estimated glomerular filtration rate (eGFR), its association with clinical disease and its predictive ability with mortality in systemic sclerosis (SSc) patients from the European Scleroderma Trials and Research Group (EUSTAR) database.METHODS: SSc patients...

Showing 37 to 38 of 38 entries