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Showing 25 to 31 of 31 entries
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Implementing and Sustaining Evidence Based Practice Through a Nursing Journal Club.

Applied nursing research : ANR

Gardner K, Kanaskie ML, Knehans AC, Salisbury S, Doheny KK, Schirm V.
PMID: 27397832
Appl Nurs Res. 2016 Aug;31:139-45. doi: 10.1016/j.apnr.2016.02.001. Epub 2016 Feb 21.

BACKGROUND: The outcomes based emphasis in nursing and health care delivery requires identification of best available evidence in order to produce quality, safe, and effective patient care. Finding, critiquing, and ultimately implementing the best available evidence for practice is...

Germline Sequencing DNA Repair Genes in 5545 Men With Aggressive and Nonaggressive Prostate Cancer.

Journal of the National Cancer Institute

Darst BF, Dadaev T, Saunders E, Sheng X, Wan P, Pooler L, Xia LY, Chanock S, Berndt SI, Gapstur SM, Stevens V, Albanes D, Weinstein SJ, Gnanapragasam V, Giles GG, Nguyen-Dumont T, Milne RL, Pomerantz M, Schmidt JA, Mucci L, Catalona WJ, Hetrick KN, Doheny KF, MacInnis RJ, Southey MC, Eeles RA, Wiklund F, Kote-Jarai Z, Conti DV, Haiman CA.
PMID: 32853339
J Natl Cancer Inst. 2021 May 04;113(5):616-625. doi: 10.1093/jnci/djaa132.

BACKGROUND: There is an urgent need to identify factors specifically associated with aggressive prostate cancer (PCa) risk. We investigated whether rare pathogenic, likely pathogenic, or deleterious (P/LP/D) germline variants in DNA repair genes are associated with aggressive PCa risk...

TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers.

Cancers

Regua AT, Aguayo NR, Jalboush SA, Doheny DL, Manore SG, Zhu D, Wong GL, Arrigo A, Wagner CJ, Yu Y, Thomas A, Chan MD, Ruiz J, Jin G, Strowd R, Sun P, Lin J, Lo HW.
PMID: 34066153
Cancers (Basel). 2021 May 12;13(10). doi: 10.3390/cancers13102340.

JAK2-STAT3 and TrkA signaling pathways have been separately implicated in aggressive breast cancers; however, whether they are co-activated or undergo functional interaction has not been thoroughly investigated. Herein we report, for the first time that STAT3 and TrkA are...

Postnatal Determination of Sex.

Science (New York, N.Y.)

Doheny JJ.
PMID: 17835230
Science. 1956 Aug 10;124(3215):277. doi: 10.1126/science.124.3215.277.

No abstract available.

Incidental genetic findings in randomized clinical trials: recommendations from the Genomics and Randomized Trials Network (GARNET).

Genome medicine

Bookman EB, Din-Lovinescu C, Worrall BB, Manolio TA, Bennett SN, Laurie C, Mirel DB, Doheny KF, Anderson GL, Wehr K, Weinshilboum R, Chen DT.
PMID: 23363732
Genome Med. 2013 Jan 30;5(1):7. doi: 10.1186/gm411. eCollection 2013.

Recommendations and guidance on how to handle the return of genetic results to patients have offered limited insight into how to approach incidental genetic findings in the context of clinical trials. This paper provides the Genomics and Randomized Trials...

Through-Space Intervalence Charge Transfer as a Mechanism for Charge Delocalization in Metal-Organic Frameworks.

Journal of the American Chemical Society

Hua C, Doheny PW, Ding B, Chan B, Yu M, Kepert CJ, D'Alessandro DM.
PMID: 29727176
J Am Chem Soc. 2018 May 30;140(21):6622-6630. doi: 10.1021/jacs.8b02638. Epub 2018 May 18.

Understanding the nature of charge transfer mechanisms in 3-dimensional metal-organic frameworks (MOFs) is an important goal owing to the possibility of harnessing this knowledge to design electroactive and conductive frameworks. These materials have been proposed as the basis for...

Author Correction: Deficiency of TET3 leads to a genome-wide DNA hypermethylation episignature in human whole blood.

NPJ genomic medicine

Levy MA, Beck DB, Metcalfe K, Douzgou S, Sithambaram S, Cottrell T, Ansar M, Kerkhof J, Mignot C, Nougues MC, Keren B, Moore HW, Oegema R, Giltay JC, Simon M, van Jaarsveld RH, Bos J, van Haelst M, Motazacker MM, Boon EMJ, Santen GWE, Ruivenkamp CAL, Alders M, Luperchio TR, Boukas L, Ramsey K, Narayanan V, Schaefer GB, Bonasio R, Doheny KF, Stevenson RE, Banka S, Sadikovic B, Fahrner JA.
PMID: 34819528
NPJ Genom Med. 2021 Nov 24;6(1):100. doi: 10.1038/s41525-021-00269-7.

No abstract available.

Showing 25 to 31 of 31 entries