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Showing 13 to 24 of 147 entries
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Efficiency of timed pregnancies in C57BL/6 and BALB/c mice by mating one male with up to four females.

Laboratory animals

Dorsch M, Wittur I, Garrels W.
PMID: 32046590
Lab Anim. 2020 Feb 11;23677219897687. doi: 10.1177/0023677219897687. Epub 2020 Feb 11.

For a wide range of biomedical approaches, an accurate estimate of the age of embryos or pups is important. Overnight mating is the method that is mostly used to establish timed pregnancies. The oestrus cycle in mice repeats every...

Structural and functional analysis of the GABARAP interaction motif (GIM).

EMBO reports

Rogov VV, Stolz A, Ravichandran AC, Rios-Szwed DO, Suzuki H, Kniss A, Löhr F, Wakatsuki S, Dötsch V, Dikic I, Dobson RC, McEwan DG.
PMID: 30518659
EMBO Rep. 2018 Dec;19(12). doi: 10.15252/embr.201847268.

No abstract available.

Evidence of Validity for a Newly Developed Digital Cognitive Test Battery.

Frontiers in psychology

Vermeent S, Dotsch R, Schmand B, Klaming L, Miller JB, van Elswijk G.
PMID: 32390918
Front Psychol. 2020 Apr 24;11:770. doi: 10.3389/fpsyg.2020.00770. eCollection 2020.

Clinical practice still relies heavily on traditional paper-and-pencil testing to assess a patient's cognitive functions. Digital technology has the potential to be an efficient and powerful alternative, but for many of the existing digital tests and test batteries the...

The Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II.

Nucleic acids research

Carnesecchi J, Boumpas P, van Nierop Y Sanchez P, Domsch K, Pinto HD, Borges Pinto P, Lohmann I.
PMID: 34931250
Nucleic Acids Res. 2021 Dec 21; doi: 10.1093/nar/gkab1250. Epub 2021 Dec 21.

Transcription factors (TFs) play a pivotal role in cell fate decision by coordinating gene expression programs. Although most TFs act at the DNA layer, few TFs bind RNA and modulate splicing. Yet, the mechanistic cues underlying TFs activity in...

HPV Vaccination: Attitude and Knowledge among German Gynecologists.

Geburtshilfe und Frauenheilkunde

Kolben TM, Dannecker C, Baltateanu K, Goess C, Starrach T, Semmlinger A, Ditsch N, Gallwas J, Mahner S, Friese K, Kolben T.
PMID: 27761028
Geburtshilfe Frauenheilkd. 2016 Oct;76(10):1074-1080. doi: 10.1055/s-0042-112813.

No abstract available.

A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1.

Oncogene

Raab M, Matthess Y, Raab CA, Gutfreund N, Dötsch V, Becker S, Sanhaji M, Strebhardt K.
PMID: 34759346
Oncogene. 2021 Nov 10; doi: 10.1038/s41388-021-02094-9. Epub 2021 Nov 10.

Polo-like kinase 1 (PLK1) is a crucial regulator of cell cycle progression. It is established that the activation of PLK1 depends on the coordinated action of Aurora-A and Bora. Nevertheless, very little is known about the spatiotemporal regulation of...

Materials (Basel, Switzerland)

Rottensteiner U, Sarker B, Heusinger D, Dafinova D, Rath SN, Beier JP, Kneser U, Horch RE, Detsch R, Boccaccini AR, Arkudas A.
PMID: 28788549
Materials (Basel). 2014 Mar 06;7(3):1957-1974. doi: 10.3390/ma7031957.

In addition to good mechanical properties needed for three-dimensional tissue engineering, the combination of alginate dialdehyde, gelatin and nano-scaled bioactive glass (45S5) is supposed to combine excellent cellular adhesion, proliferation and differentiation properties, good biocompatibility and predictable degradation rates....

Comparison of Hydrogels for the Development of Well-Defined 3D Cancer Models of Breast Cancer and Melanoma.

Cancers

Schmid R, Schmidt SK, Hazur J, Detsch R, Maurer E, Boccaccini AR, Hauptstein J, Teßmar J, Blunk T, Schrüfer S, Schubert DW, Horch RE, Bosserhoff AK, Arkudas A, Kengelbach-Weigand A.
PMID: 32824576
Cancers (Basel). 2020 Aug 17;12(8). doi: 10.3390/cancers12082320.

Bioprinting offers the opportunity to fabricate precise 3D tumor models to study tumor pathophysiology and progression. However, the choice of the bioink used is important. In this study, cell behavior was studied in three mechanically and biologically different hydrogels...

Hemodynamic early goal-directed therapy: Explaining the fine print.

International journal of critical illness and injury science

Goldthwaite Z, Firstenberg MS, Botsch A.
PMID: 31334045
Int J Crit Illn Inj Sci. 2019 Apr-Jun;9(2):54-56. doi: 10.4103/IJCIIS.IJCIIS_38_19.

The management of patients after cardiothoracic surgery can be very complex. Variabilities exist in hemodynamic status after cardiac surgery and the use of cardiopulmonary bypass - all of which can have a significant impact on myocardial Frank-Starling curves. Typically,...

Evaluation of Electrospun Poly(ε-Caprolactone)/Gelatin Nanofiber Mats Containing Clove Essential Oil for Antibacterial Wound Dressing.

Pharmaceutics

Unalan I, Endlein SJ, Slavik B, Buettner A, Goldmann WH, Detsch R, Boccaccini AR.
PMID: 31683863
Pharmaceutics. 2019 Nov 01;11(11). doi: 10.3390/pharmaceutics11110570.

The objective of this study was to produce antibacterial poly(ε-caprolactone) (PCL)-gelatin (GEL) electrospun nanofiber mats containing clove essential oil (CLV) using glacial acetic acid (GAA) as a "benign" (non-toxic) solvent. The addition of CLV increased the fiber diameter from...

Influence of In-Situ Electrochemical Oxidation on Implant Surface and Colonizing Microorganisms Evaluated by Scanning Electron Microscopy.

Materials (Basel, Switzerland)

Göltz M, Koch M, Detsch R, Karl M, Burkovski A, Rosiwal S.
PMID: 31801251
Materials (Basel). 2019 Nov 30;12(23). doi: 10.3390/ma12233977.

Peri-implantitis is a worldwide increasing health problem, caused by infection of tissue and bone around an implant by biofilm-forming microorganisms. Effects of peri-implantitis treatment using mechanical debridement, air particle abrasion and electrochemical disinfection on implant surface integrity were compared....

In situ observation of helium and argon release during fluid-pressure-triggered rock deformation.

Scientific reports

Roques C, Weber UW, Brixel B, Krietsch H, Dutler N, Brennwald MS, Villiger L, Doetsch J, Jalali M, Gischig V, Amann F, Valley B, Klepikova M, Kipfer R.
PMID: 32332786
Sci Rep. 2020 Apr 24;10(1):6949. doi: 10.1038/s41598-020-63458-x.

Temporal changes in groundwater chemistry can reveal information about the evolution of flow path connectivity during crustal deformation. Here, we report transient helium and argon concentration anomalies monitored during a series of hydraulic reservoir stimulation experiments measured with an...

Showing 13 to 24 of 147 entries