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Showing 217 to 228 of 228 entries
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RiFNet: Automated rib fracture detection in postmortem computed tomography.

Forensic science, medicine, and pathology

Ibanez V, Gunz S, Erne S, Rawdon EJ, Ampanozi G, Franckenberg S, Sieberth T, Affolter R, Ebert LC, Dobay A.
PMID: 34709561
Forensic Sci Med Pathol. 2021 Oct 28; doi: 10.1007/s12024-021-00431-8. Epub 2021 Oct 28.

Imaging techniques are widely used for medical diagnostics. In some cases, a lack of medical practitioners who can manually analyze the images can lead to a bottleneck. Consequently, we developed a custom-made convolutional neural network (RiFNet = Rib Fracture...

Ru(ii)/BODIPY core co-encapsulated ratiometric nanotools for intracellular O.

RSC chemical biology

Gkika KS, Kargaard A, Burke CS, Dolan C, Heise A, Keyes TE.
PMID: 34704057
RSC Chem Biol. 2021 Jul 28;2(5):1520-1533. doi: 10.1039/d1cb00102g. eCollection 2021 Oct 07.

Oxygen is a crucial reagent in many biochemical processes within living cells and its concentration can be an effective marker in disease, particularly in cancer where tissue hypoxia has been shown to indicate tumour growth. Probes that can reflect...

Chemical hazards in smoked meat and fish.

Food science & nutrition

Iko Afé OH, Kpoclou YE, Douny C, Anihouvi VB, Igout A, Mahillon J, Hounhouigan DJ, Scippo ML.
PMID: 34925818
Food Sci Nutr. 2021 Oct 18;9(12):6903-6922. doi: 10.1002/fsn3.2633. eCollection 2021 Dec.

This review aims to give an insight into the main hazards currently found in smoked meat and fish products. Literature research was carried out on international databases such as Access to Global Online Research in Agriculture (AGORA) database, Science...

The relationship between wasting and stunting in young children: A systematic review.

Maternal & child nutrition

Thurstans S, Sessions N, Dolan C, Sadler K, Cichon B, Isanaka S, Roberfroid D, Stobaugh H, Webb P, Khara T.
PMID: 34486229
Matern Child Nutr. 2022 Jan;18(1):e13246. doi: 10.1111/mcn.13246. Epub 2021 Sep 05.

In 2014, the Emergency Nutrition Network published a report on the relationship between wasting and stunting. We aim to review evidence generated since that review to better understand the implications for improving child nutrition, health and survival. We conducted...

Interlaboratory variability of activated protein C resistance using the ETP-based APC resistance assay.

Research and practice in thrombosis and haemostasis

Morimont L, Didembourg M, Haguet H, Modaffari É, Tillier M, Bouvy C, Lebreton A, Dogné JM, Douxfils J.
PMID: 34761157
Res Pract Thromb Haemost. 2021 Nov 02;5(7):e12612. doi: 10.1002/rth2.12612. eCollection 2021 Oct.

BACKGROUND AND OBJECTIVE: Although the endogenous thrombin potential (ETP)-based activated protein C (APC) resistance is recommended for the development of steroid contraceptive agents, one of the main limitations of this technique was its lack of standardization, which hampered study-to-study...

Impact of centrifugation on thrombin generation in healthy subjects and in patients treated with direct oral anticoagulants.

International journal of laboratory hematology

Hardy M, Dellanoce C, Douxfils J, Carlo A, Lessire S, Bouvy C, Testa S, Mullier F.
PMID: 34252264
Int J Lab Hematol. 2021 Dec;43(6):1585-1592. doi: 10.1111/ijlh.13655. Epub 2021 Jul 12.

INTRODUCTION: Double centrifugation before freezing is recommended before thrombin generation assays (TGA). However, this procedure is not mandatory for routine hemostasis tests, precluding the use of these samples for TGA. The aim of this study is to assess the...

Prognostic value of main pulmonary artery diameter to ascending aorta diameter ratio in patients with advanced heart failure.

Acta cardiologica

Dogan C, Bayram Z, Efe SC, Acar RD, Tanboga IH, Karagoz A, Havan N, Ozer T, Uslu A, Kırali MK, Kaymaz C, Ozdemir N.
PMID: 33501898
Acta Cardiol. 2021 Dec;76(10):1108-1116. doi: 10.1080/00015385.2021.1872186. Epub 2021 Jan 27.

OBJECTIVES AND BACKGROUND: In this study we assessed the prognostic value of main pulmonary artery diameter and its ratio to ascending aorta diameter (P/Ao ratio) in advanced heart failure patients.METHODS: Patients with advanced heart failure who were candidates for...

Interpretable machine learning model to detect chemically adulterated urine samples analyzed by high resolution mass spectrometry.

Clinical chemistry and laboratory medicine

Streun GL, Steuer AE, Ebert LC, Dobay A, Kraemer T.
PMID: 33742969
Clin Chem Lab Med. 2021 Mar 22;59(8):1392-1399. doi: 10.1515/cclm-2021-0010. Print 2021 Jul 27.

OBJECTIVES: Urine sample manipulation including substitution, dilution, and chemical adulteration is a continuing challenge for workplace drug testing, abstinence control, and doping control laboratories. The simultaneous detection of sample manipulation and prohibited drugs within one single analytical measurement would...

Minding metabolism: targeted interventions to improve cardio-metabolic monitoring across early and chronic psychosis.

Irish journal of medical science

Kelly JR, Gounden P, McLoughlin A, Legris Z, O'Carroll T, McCafferty R, Marques L, Haran M, Farrelly R, Loughrey K, Flynn G, Corvin A, Dolan C.
PMID: 33683562
Ir J Med Sci. 2021 Mar 08; doi: 10.1007/s11845-021-02576-5. Epub 2021 Mar 08.

BACKGROUND: Antipsychotics (APs) increase weight, metabolic syndrome, diabetes and cardiovascular disease. Guidelines recommend cardio-metabolic monitoring at initial assessment, at 3 months and then annually in people prescribed APs.AIM: To determine the rates of cardio-metabolic monitoring in AP treated early...

Prevalence of Staphylococcus aureus in wild hedgehogs (Erinaceus europaeus) and first report of mecC-MRSA in Hungary.

The Science of the total environment

Sahin-Tóth J, Albert E, Juhász A, Ghidán Á, Juhász J, Horváth A, Steward MC, Dobay O.
PMID: 34995585
Sci Total Environ. 2022 Jan 04;815:152858. doi: 10.1016/j.scitotenv.2021.152858. Epub 2022 Jan 04.

In 2011 mecC, a new mecA gene homologue, was described in a bovine isolate in the UK. Since then, mecC-positive methicillin-resistant Staphylococcus aureus (mecC-MRSA) has also been found in wild animals. An especially high prevalence of mecC-MRSA has been...

Transplastomic Tomato Plants Expressing Insect-Specific Double-Stranded RNAs: A Protocol Based on Biolistic Transformation.

Methods in molecular biology (Clifton, N.J.)

Kaplanoglu E, Kolotilin I, Menassa R, Donly C.
PMID: 34495519
Methods Mol Biol. 2022;2360:235-252. doi: 10.1007/978-1-0716-1633-8_18.

Expressing insecticidal double-stranded RNA (dsRNA) molecules in plant plastids is a novel approach for in planta production of dsRNA that has enormous potential for developing improved plant-mediated RNA interference (RNAi) strategies for insect pest control. In this chapter, we...

Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity.

Science advances

Mbianda J, Bakail M, André C, Moal G, Perrin ME, Pinna G, Guerois R, Becher F, Legrand P, Traoré S, Douat C, Guichard G, Ochsenbein F.
PMID: 33741589
Sci Adv. 2021 Mar 19;7(12). doi: 10.1126/sciadv.abd9153. Print 2021 Mar.

Sequence-specific oligomers with predictable folding patterns, i.e., foldamers, provide new opportunities to mimic α-helical peptides and design inhibitors of protein-protein interactions. One major hurdle of this strategy is to retain the correct orientation of key side chains involved in...

Showing 217 to 228 of 228 entries