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Revealing NOTCH-dependencies in synaptic targets associated with Alzheimer's disease.

Molecular and cellular neurosciences

Perna A, Marathe S, Dreos R, Falquet L, Akarsu Egger H, Auber LA.
PMID: 34314836
Mol Cell Neurosci. 2021 Sep;115:103657. doi: 10.1016/j.mcn.2021.103657. Epub 2021 Jul 24.

Recent studies have identified NOTCH signaling as a contributor of neurodegeneration including Alzheimer's disease' (AD) pathophysiology. As part of the efforts to understand molecular mechanisms and players involved in neurodegenerative dementia, we employed transgenic mouse models with Notch1 and...

Showing 229 to 229 of 229 entries