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Showing 193 to 196 of 196 entries
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Design for Solubility May Reveal Induction of Amide Hydrogen/Deuterium Exchange by Protein Self-Association.

Journal of molecular biology

Trainor K, Doyle CM, Metcalfe-Roach A, Steckner J, Lipovšek D, Malakian H, Langley D, Krystek SR, Meiering EM.
PMID: 34902431
J Mol Biol. 2021 Dec 10;434(2):167398. doi: 10.1016/j.jmb.2021.167398. Epub 2021 Dec 10.

Structural heterogeneity often constrains the characterization of aggregating proteins to indirect or low-resolution methods, obscuring mechanistic details of association. Here, we report progress in understanding the aggregation of Adnectins, engineered binding proteins with an immunoglobulin-like fold. We rationally design...

Single photon double and triple ionization of allene.

Physical chemistry chemical physics : PCCP

Ideböhn V, Sterling AJ, Wallner M, Olsson E, Squibb RJ, Miniotaite U, Forsmalm E, Forsmalm M, Stranges S, Dyke JM, Duarte F, Eland JHD, Feifel R.
PMID: 34927639
Phys Chem Chem Phys. 2021 Dec 20; doi: 10.1039/d1cp04666g. Epub 2021 Dec 20.

Double and triple ionization of allene are investigated using electron-electron, ion-ion, electron-electron-ion and electron-electron-ion-ion (ee, ii, eei, eeii) coincidence spectroscopies at selected photon energies. The results provide supporting evidence for a previously proposed roaming mechanism in H

Ethics Consultation in U.S. Hospitals: Opinions of Ethics Practitioners.

The American journal of bioethics : AJOB

Fox E, Tarzian AJ, Danis M, Duke CC.
PMID: 33769222
Am J Bioeth. 2021 Mar 26;1-19. doi: 10.1080/15265161.2021.1893550. Epub 2021 Mar 26.

To design effective strategies to improve ethics consultation (EC) practices, it is important to understand the views of ethics practitioners. Previous U.S. studies of ethics practitioners have overrepresented the views of academic bioethicists. To help inform EC improvement efforts,...

Ethics Consultation in U.S. Hospitals: Determinants of Consultation Volume.

The American journal of bioethics : AJOB

Fox E, Duke CC.
PMID: 33769227
Am J Bioeth. 2021 Mar 26;1-7. doi: 10.1080/15265161.2021.1893548. Epub 2021 Mar 26.

The annual volume of ethics consultations (ECs) has been a topic of interest in the bioethics literature, in part because of its presumed relationship to quality. To better understand factors associated with EC volume, we used multiple linear regression...

Showing 193 to 196 of 196 entries