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Showing 25 to 36 of 208 entries
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Trends in relative survival in patients with a diagnosis of hepatocellular carcinoma in Ontario: a population-based retrospective cohort study.

CMAJ open

Thein HH, Khoo E, Campitelli MA, Zaheen A, Yi Q, De P, Earle CC.
PMID: 26389099
CMAJ Open. 2015 Apr 02;3(2):E208-16. doi: 10.9778/cmajo.20140118. eCollection 2015.

BACKGROUND: The incidence of hepatocellular carcinoma (HCC) is increasing and survival rates are poor. Our objectives were to estimate the relative survival over time in patients with HCC in Ontario and to examine potential factors associated with excess mortality...

An examination of factors affecting the efficiency ofAgrobacterium-mediated transformation of tomato.

Plant cell reports

Frary A, Earle ED.
PMID: 24177560
Plant Cell Rep. 1996 Dec;16(3):235-40. doi: 10.1007/BF01890875.

An improved protocol forAgrobacterium-mediated transformation of the tomato cultivar Moneymaker was developed by examining the effects of six different factors on the efficiency of transformation. Explant size, explant orientation, gelling agent and plate sealant were found to affect transformation...

Sleep Facilitates Generalisation of Accent Adaptation to a New Talker.

Language, cognition and neuroscience

Xie X, Earle FS, Myers EB.
PMID: 29372171
Lang Cogn Neurosci. 2018;33(2):196-210. doi: 10.1080/23273798.2017.1369551. Epub 2017 Aug 29.

Lexically-guided phonetic retuning helps listeners adapt to the phonetic "fingerprint" of a talker. Previous findings show that listeners can generalise from one accented talker to another accented talker, but only for phonetically similar talkers. We tested whether sleep-mediated consolidation...

Color, composition, and thermal environment of Kuiper Belt object (486958) Arrokoth.

Science (New York, N.Y.)

Grundy WM, Bird MK, Britt DT, Cook JC, Cruikshank DP, Howett CJA, Krijt S, Linscott IR, Olkin CB, Parker AH, Protopapa S, Ruaud M, Umurhan OM, Young LA, Dalle Ore CM, Kavelaars JJ, Keane JT, Pendleton YJ, Porter SB, Scipioni F, Spencer JR, Stern SA, Verbiscer AJ, Weaver HA, Binzel RP, Buie MW, Buratti BJ, Cheng A, Earle AM, Elliott HA, Gabasova L, Gladstone GR, Hill ME, Horanyi M, Jennings DE, Lunsford AW, McComas DJ, McKinnon WB, McNutt RL, Moore JM, Parker JW, Quirico E, Reuter DC, Schenk PM, Schmitt B, Showalter MR, Singer KN, Weigle GE, Zangari AM.
PMID: 32054693
Science. 2020 Feb 28;367(6481). doi: 10.1126/science.aay3705. Epub 2020 Feb 13.

The outer Solar System object (486958) Arrokoth (provisional designation 2014 MU

Women, marital status, and symptoms of depression in a midlife national sample.

Journal of women & aging

Earle JR, Harris CT, Longino CF, Smith MH.
PMID: 9870051
J Women Aging. 1998;10(1):41-57. doi: 10.1300/j074v10n01_04.

Previous studies of the correlates of depression among women have not generally been based on adequate midlife samples or precision in the specification of marital status categories. The present analysis is designed to address these deficiencies and is based...

Breast Density and Risk of Interval Cancers: The Effect of Annual Versus Biennial Screening Mammography Policies in Canada.

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

Seely JM, Peddle SE, Yang H, Chiarelli AM, McCallum M, Narasimhan G, Zakaria D, Earle CC, Fung S, Bryant H, Nicholson E, Politis C, Berg WA.
PMID: 34279132
Can Assoc Radiol J. 2021 Jul 19;8465371211027958. doi: 10.1177/08465371211027958. Epub 2021 Jul 19.

Regular screening mammography reduces breast cancer mortality. However, in women with dense breasts, the performance of screening mammography is reduced, which is reflected in higher interval cancer rates (ICR). In Canada, population-based screening mammography programs generally screen women biennially;...

Remote, proactive, telephone based management of toxicity in outpatients during adjuvant or neoadjuvant chemotherapy for early stage breast cancer: pragmatic, cluster randomised trial.

BMJ (Clinical research ed.)

Krzyzanowska MK, Julian JA, Gu CS, Powis M, Li Q, Enright K, Howell D, Earle CC, Gandhi S, Rask S, Brezden-Masley C, Dent S, Hajra L, Freeman O, Spadafora S, Hamm C, Califaretti N, Trudeau M, Levine MN, Amir E, Bordeleau L, Chiarotto JA, Elser C, Husain J, Laferriere N, Rahim Y, Robinson AG, Vandenberg T, Grunfeld E.
PMID: 34880055
BMJ. 2021 Dec 08;375:e066588. doi: 10.1136/bmj-2021-066588.

OBJECTIVE: To evaluate the effectiveness of remote proactive management of toxicities during chemotherapy for early stage breast cancer.DESIGN: Pragmatic, cluster randomised trial.SETTING: 20 cancer centres in Ontario, Canada, allocated by covariate constrained randomisation to remote management of toxicities or...

High-Intensity vs Low-Intensity Knowledge Translation Interventions for Surgeons and Their Association With Process and Outcome Measures Among Patients Undergoing Rectal Cancer Surgery.

JAMA network open

Simunovic M, Urbach DR, Fahim C, O'Brien MA, Earle CC, Brouwers M, Gatov E, Grubac V, McCormack D, Baxter N.
PMID: 34269805
JAMA Netw Open. 2021 Jul 01;4(7):e2117536. doi: 10.1001/jamanetworkopen.2021.17536.

IMPORTANCE: Surgeon-directed knowledge translation (KT) interventions for rectal cancer surgery are designed to improve patient measures, such as rates of permanent colostomy and in-hospital mortality, and to improve survival.OBJECTIVE: To evaluate the association of sustained, iterative, integrated KT rectal...

Real-world Safety of Bevacizumab with First-line Combination Chemotherapy in Patients with Metastatic Colorectal Cancer: Population-based Retrospective Cohort Studies in Three Canadian Provinces.

Clinical oncology (Royal College of Radiologists (Great Britain))

Beca JM, Dai WF, Pataky RE, Tran D, Dvorani E, Isaranuwatchai W, Peacock S, Alvi R, Cheung WY, Earle CC, Gavura S, Chan KKW.
PMID: 34456106
Clin Oncol (R Coll Radiol). 2022 Jan;34(1):e7-e17. doi: 10.1016/j.clon.2021.08.009. Epub 2021 Aug 26.

AIMS: To examine the real-world safety of adding bevacizumab to first-line irinotecan-based chemotherapy for patients with metastatic colorectal cancer (mCRC).MATERIALS AND METHODS: Patients diagnosed with CRC in three Canadian provinces (Ontario, Saskatchewan and British Columbia) who received publicly funded...

Seminary Students and Physical Health: Beliefs, Behaviors, and Barriers.

Journal of religion and health

Johnston EF, Eagle DE, Corneli A, Perry B, Proeschold-Bell RJ.
PMID: 35034253
J Relig Health. 2022 Jan 16; doi: 10.1007/s10943-021-01480-7. Epub 2022 Jan 16.

As an occupational group, clergy exhibit numerous physical health problems. Given the physical health problems faced by clergy, understanding where physical health falls within the priorities of seminary students, the ways students conceptualize physical health, and how seminary students...

The Association of Drug-Funding Reimbursement With Survival Outcomes and Use of New Systemic Therapies Among Patients With Advanced Pancreatic Cancer.

JAMA network open

Raphael MJ, Raskin W, Habbous S, Tai X, Beca J, Dai WF, Arias J, Forbes L, Gavura S, Biagi JJ, Earle CC, Chan KKW.
PMID: 34779846
JAMA Netw Open. 2021 Nov 01;4(11):e2133388. doi: 10.1001/jamanetworkopen.2021.33388.

IMPORTANCE: Gemcitabine-nab-paclitaxel (GEMNAB) and fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) both improve survival of patients with advanced pancreatic cancer when compared with single-agent gemcitabine in clinical trials.OBJECTIVE: To describe changes in the survival of patients with advanced pancreatic cancer...

Real-world Safety of Bevacizumab with First-line Combination Chemotherapy in Patients with Metastatic Colorectal Cancer: Population-based Retrospective Cohort Studies in Three Canadian Provinces.

Clinical oncology (Royal College of Radiologists (Great Britain))

Beca JM, Dai WF, Pataky RE, Tran D, Dvorani E, Isaranuwatchai W, Peacock S, Alvi R, Cheung WY, Earle CC, Gavura S, Chan KKW.
PMID: 34456106
Clin Oncol (R Coll Radiol). 2022 Jan;34(1):e7-e17. doi: 10.1016/j.clon.2021.08.009. Epub 2021 Aug 26.

AIMS: To examine the real-world safety of adding bevacizumab to first-line irinotecan-based chemotherapy for patients with metastatic colorectal cancer (mCRC).MATERIALS AND METHODS: Patients diagnosed with CRC in three Canadian provinces (Ontario, Saskatchewan and British Columbia) who received publicly funded...

Showing 25 to 36 of 208 entries