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Mitochondrial DNA Affects the Expression of Nuclear Genes Involved in Immune and Stress Responses in a Breast Cancer Model.

Frontiers in physiology

Grasso C, Eccles DA, Boukalova S, Fabre MS, Dawson RH, Neuzil J, Herst PM, Berridge MV.
PMID: 33329014
Front Physiol. 2020 Nov 24;11:543962. doi: 10.3389/fphys.2020.543962. eCollection 2020.

Tumor cells without mitochondrial (mt) DNA (ρ

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Grasso C, Eccles DA, Boukalova S, et al. Mitochondrial DNA Affects the Expression of Nuclear Genes Involved in Immune and Stress Responses in a Breast Cancer Model. Front Physiol. 2020;11:543962doi: 10.3389/fphys.2020.543962.
Grasso, C., Eccles, D. A., Boukalova, S., Fabre, M. S., Dawson, R. H., Neuzil, J., Herst, P. M., & Berridge, M. V. (2020). Mitochondrial DNA Affects the Expression of Nuclear Genes Involved in Immune and Stress Responses in a Breast Cancer Model. Frontiers in physiology, 11543962. https://doi.org/10.3389/fphys.2020.543962
Grasso, Carole, et al. "Mitochondrial DNA Affects the Expression of Nuclear Genes Involved in Immune and Stress Responses in a Breast Cancer Model." Frontiers in physiology vol. 11 (2020): 543962. doi: https://doi.org/10.3389/fphys.2020.543962
Grasso C, Eccles DA, Boukalova S, Fabre MS, Dawson RH, Neuzil J, Herst PM, Berridge MV. Mitochondrial DNA Affects the Expression of Nuclear Genes Involved in Immune and Stress Responses in a Breast Cancer Model. Front Physiol. 2020 Nov 24;11:543962. doi: 10.3389/fphys.2020.543962. eCollection 2020. PMID: 33329014; PMCID: PMC7732479.
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Selective Breeding for Low and High .

Insects

De la Mora A, Emsen B, Morfin N, Borges D, Eccles L, Kelly PG, Goodwin PH, Guzman-Novoa E.
PMID: 33291568
Insects. 2020 Dec 04;11(12). doi: 10.3390/insects11120864.

After two years of bidirectional selection for low and high rates of

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De la Mora A, Emsen B, Morfin N, et al. Selective Breeding for Low and High . Insects. 2020;11(12)doi: 10.3390/insects11120864.
De la Mora, A., Emsen, B., Morfin, N., Borges, D., Eccles, L., Kelly, P. G., Goodwin, P. H., & Guzman-Novoa, E. (2020). Selective Breeding for Low and High . Insects, 11(12), . https://doi.org/10.3390/insects11120864
De la Mora, Alvaro, et al. "Selective Breeding for Low and High ." Insects vol. 11,12 (2020). doi: https://doi.org/10.3390/insects11120864
De la Mora A, Emsen B, Morfin N, Borges D, Eccles L, Kelly PG, Goodwin PH, Guzman-Novoa E. Selective Breeding for Low and High . Insects. 2020 Dec 04;11(12). doi: 10.3390/insects11120864. PMID: 33291568; PMCID: PMC7761820.
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Streamlining the image-guided radiotherapy process for proton beam therapy.

The British journal of radiology

Davies LSC, McHugh L, Aznar M, Lindsay J, Eccles C.
PMID: 34520675
Br J Radiol. 2021 Dec;94(1128):20210764. doi: 10.1259/bjr.20210764. Epub 2021 Sep 14.

OBJECTIVES: This work evaluated the on-treatment imaging workflow in the UK's first proton beam therapy (PBT) centre, with a view to reducing times and unnecessary imaging doses to patients.METHODS: Imaging dose and timing data from the first 20 patients...

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Davies LSC, McHugh L, Aznar M, et al. Streamlining the image-guided radiotherapy process for proton beam therapy. Br J Radiol. 2021;94(1128):20210764doi: 10.1259/bjr.20210764.
Davies, L. S. C., McHugh, L., Aznar, M., Lindsay, J., & Eccles, C. (2021). Streamlining the image-guided radiotherapy process for proton beam therapy. The British journal of radiology, 94(1128), 20210764. https://doi.org/10.1259/bjr.20210764
Davies, Lucy Siew Chen, et al. "Streamlining the image-guided radiotherapy process for proton beam therapy." The British journal of radiology vol. 94,1128 (2021): 20210764. doi: https://doi.org/10.1259/bjr.20210764
Davies LSC, McHugh L, Aznar M, Lindsay J, Eccles C. Streamlining the image-guided radiotherapy process for proton beam therapy. Br J Radiol. 2021 Dec;94(1128):20210764. doi: 10.1259/bjr.20210764. Epub 2021 Sep 14. PMID: 34520675; PMCID: PMC8631028.
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Management of acute upper respiratory tract infection: the role of early intervention.

Expert review of respiratory medicine

Wang Y, Eccles R, Bell J, Chua AH, Salvi S, Schellack N, Marks P, Wong YC.
PMID: 34613861
Expert Rev Respir Med. 2021 Dec;15(12):1517-1523. doi: 10.1080/17476348.2021.1988569. Epub 2021 Oct 19.

INTRODUCTION: Upper respiratory tract infection (URTI) is an illness caused by an acute infection by viruses or bacteria of the nose, sinuses, pharynx, and larynx. Most URTIs are short, mild, and self-limiting, but some can lead to serious complications,...

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Wang Y, Eccles R, Bell J, et al. Management of acute upper respiratory tract infection: the role of early intervention. Expert Rev Respir Med. 2021;15(12):1517-1523doi: 10.1080/17476348.2021.1988569.
Wang, Y., Eccles, R., Bell, J., Chua, A. H., Salvi, S., Schellack, N., Marks, P., & Wong, Y. C. (2021). Management of acute upper respiratory tract infection: the role of early intervention. Expert review of respiratory medicine, 15(12), 1517-1523. https://doi.org/10.1080/17476348.2021.1988569
Wang, De Yun, et al. "Management of acute upper respiratory tract infection: the role of early intervention." Expert review of respiratory medicine vol. 15,12 (2021): 1517-1523. doi: https://doi.org/10.1080/17476348.2021.1988569
Wang Y, Eccles R, Bell J, Chua AH, Salvi S, Schellack N, Marks P, Wong YC. Management of acute upper respiratory tract infection: the role of early intervention. Expert Rev Respir Med. 2021 Dec;15(12):1517-1523. doi: 10.1080/17476348.2021.1988569. Epub 2021 Oct 19. PMID: 34613861.
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Quantifying evidence toward pathogenicity for rare phenotypes: The case of succinate dehydrogenase genes, SDHB and SDHD.

Genetics in medicine : official journal of the American College of Medical Genetics

Garrett A, Loveday C, King L, Butler S, Robinson R, Horton C, Yussuf A, Choi S, Torr B, Durkie M, Burghel GJ, Drummond J, Berry I, Wallace A, Callaway A, Eccles D, Tischkowitz M, Tatton-Brown K, Snape K, McVeigh T, Izatt L, Woodward ER, Burnichon N, Gimenez-Roqueplo AP, Mazzarotto F, Whiffin N, Ware J, Hanson H, Pesaran T, LaDuca H, Buffet A, Maher ER, Turnbull C.
PMID: 34906457
Genet Med. 2022 Jan;24(1):41-50. doi: 10.1016/j.gim.2021.08.004. Epub 2021 Nov 30.

PURPOSE: The weight of the evidence to attach to observation of a novel rare missense variant in SDHB or SDHD in individuals with the rare neuroendocrine tumors, pheochromocytomas and paragangliomas (PCC/PGL), is uncertain.METHODS: We compared the frequency of SDHB...

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Garrett A, Loveday C, King L, et al. Quantifying evidence toward pathogenicity for rare phenotypes: The case of succinate dehydrogenase genes, SDHB and SDHD. Genet Med. 2021;24(1):41-50doi: 10.1016/j.gim.2021.08.004.
Garrett, A., Loveday, C., King, L., Butler, S., Robinson, R., Horton, C., Yussuf, A., Choi, S., Torr, B., Durkie, M., Burghel, G. J., Drummond, J., Berry, I., Wallace, A., Callaway, A., Eccles, D., Tischkowitz, M., Tatton-Brown, K., Snape, K., McVeigh, T., Izatt, L., Woodward, E. R., Burnichon, N., Gimenez-Roqueplo, A. P., Mazzarotto, F., Whiffin, N., Ware, J., Hanson, H., Pesaran, T., LaDuca, H., Buffet, A., Maher, E. R., Turnbull, C. (2022). Quantifying evidence toward pathogenicity for rare phenotypes: The case of succinate dehydrogenase genes, SDHB and SDHD. Genetics in medicine : official journal of the American College of Medical Genetics, 24(1), 41-50. https://doi.org/10.1016/j.gim.2021.08.004
Garrett, Alice, et al. "Quantifying evidence toward pathogenicity for rare phenotypes: The case of succinate dehydrogenase genes, SDHB and SDHD." Genetics in medicine : official journal of the American College of Medical Genetics vol. 24,1 (2022): 41-50. doi: https://doi.org/10.1016/j.gim.2021.08.004
Garrett A, Loveday C, King L, Butler S, Robinson R, Horton C, Yussuf A, Choi S, Torr B, Durkie M, Burghel GJ, Drummond J, Berry I, Wallace A, Callaway A, Eccles D, Tischkowitz M, Tatton-Brown K, Snape K, McVeigh T, Izatt L, Woodward ER, Burnichon N, Gimenez-Roqueplo AP, Mazzarotto F, Whiffin N, Ware J, Hanson H, Pesaran T, LaDuca H, Buffet A, Maher ER, Turnbull C. Quantifying evidence toward pathogenicity for rare phenotypes: The case of succinate dehydrogenase genes, SDHB and SDHD. Genet Med. 2022 Jan;24(1):41-50. doi: 10.1016/j.gim.2021.08.004. Epub 2021 Nov 30. PMID: 34906457.
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Evaluation of Virtual Screening Strategies for the Identification of γ-Secretase Inhibitors and Modulators.

Molecules (Basel, Switzerland)

Ioppolo A, Eccles M, Groth D, Verdile G, Agostino M.
PMID: 35011410
Molecules. 2021 Dec 28;27(1). doi: 10.3390/molecules27010176.

γ-Secretase is an intramembrane aspartyl protease that is important in regulating normal cell physiology via cleavage of over 100 transmembrane proteins, including Amyloid Precursor Protein (APP) and Notch family receptors. However, aberrant proteolysis of substrates has implications in the...

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Ioppolo A, Eccles M, Groth D, et al. Evaluation of Virtual Screening Strategies for the Identification of γ-Secretase Inhibitors and Modulators. Molecules. 2021;27(1)doi: 10.3390/molecules27010176.
Ioppolo, A., Eccles, M., Groth, D., Verdile, G., & Agostino, M. (2021). Evaluation of Virtual Screening Strategies for the Identification of γ-Secretase Inhibitors and Modulators. Molecules (Basel, Switzerland), 27(1), . https://doi.org/10.3390/molecules27010176
Ioppolo, Alicia, et al. "Evaluation of Virtual Screening Strategies for the Identification of γ-Secretase Inhibitors and Modulators." Molecules (Basel, Switzerland) vol. 27,1 (2021). doi: https://doi.org/10.3390/molecules27010176
Ioppolo A, Eccles M, Groth D, Verdile G, Agostino M. Evaluation of Virtual Screening Strategies for the Identification of γ-Secretase Inhibitors and Modulators. Molecules. 2021 Dec 28;27(1). doi: 10.3390/molecules27010176. PMID: 35011410; PMCID: PMC8746326.
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Response.

Clinical medicine (London, England)

Eccles JA, Davies KA.
PMID: 33762400
Clin Med (Lond). 2021 Mar;21(2):e243. doi: 10.7861/clinmed.Let.21.2.5.

No abstract available.

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Eccles JA, Davies KA. Response. Clin Med (Lond). 2021;21(2):e243doi: 10.7861/clinmed.Let.21.2.5.
Eccles, J. A., & Davies, K. A. (2021). Response. Clinical medicine (London, England), 21(2), e243. https://doi.org/10.7861/clinmed.Let.21.2.5
Eccles, Jessica A, and Davies, Kevin A. "Response." Clinical medicine (London, England) vol. 21,2 (2021): e243. doi: https://doi.org/10.7861/clinmed.Let.21.2.5
Eccles JA, Davies KA. Response. Clin Med (Lond). 2021 Mar;21(2):e243. doi: 10.7861/clinmed.Let.21.2.5. PMID: 33762400; PMCID: PMC8002804.
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Structured career pathways in academic primary care.

Foy R, Eccles M.
UIID-AD: 995
2008;25:63-67. doi: 10.1093/fampra/cmn004.

Research in primary care has much to offer researchers and ultimately efforts to improve population health and health care. There is a need for capacity building and efforts to improve the science of research in this field. This article...

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Foy R, Eccles M. Structured career pathways in academic primary care. 2008;25:63-67doi: 10.1093/fampra/cmn004.
Foy, R., & Eccles, M. (2008). Structured career pathways in academic primary care. 2563-67. https://doi.org/10.1093/fampra/cmn004
Foy, R, and Eccles, M. "Structured career pathways in academic primary care." vol. 25 (2008): 63-67. doi: https://doi.org/10.1093/fampra/cmn004
Foy R, Eccles M. Structured career pathways in academic primary care. 2008;25:63-67. doi: 10.1093/fampra/cmn004. UIID-AD: 995.
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Showing 361 to 368 of 368 entries