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Showing 397 to 406 of 406 entries
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Micropattern platform promotes extracellular matrix remodeling by human PSC-derived cardiac fibroblasts and enhances contractility of co-cultured cardiomyocytes.

Physiological reports

Napiwocki BN, Stempien A, Lang D, Kruepke RA, Kim G, Zhang J, Eckhardt LL, Glukhov AV, Kamp TJ, Crone WC.
PMID: 34617673
Physiol Rep. 2021 Oct;9(19):e15045. doi: 10.14814/phy2.15045.

In native heart tissue, cardiac fibroblasts provide the structural framework of extracellular matrix (ECM) while also influencing the electrical and mechanical properties of cardiomyocytes. Recent advances in the field of stem cell differentiation have led to the availability of...

Sun Protection and Sunburn in Children Aged 1-10 Years in Germany: Prevalence and Determinants.

Children (Basel, Switzerland)

Görig T, Södel C, Pfahlberg AB, Gefeller O, Breitbart EW, Diehl K.
PMID: 34438559
Children (Basel). 2021 Jul 31;8(8). doi: 10.3390/children8080668.

Seeking shade, the use of textile sun protection and sunscreen, and protecting one's eyes by wearing sunglasses are recommended sun protection measures in children. We aimed to quantify the use of these measures as well as the prevalence of...

Shared Decision Making in Cardiac Electrophysiology Procedures and Arrhythmia Management.

Circulation. Arrhythmia and electrophysiology

Chung MK, Fagerlin A, Wang PJ, Ajayi TB, Allen LA, Baykaner T, Benjamin EJ, Branda M, Cavanaugh KL, Chen LY, Crossley GH, Delaney RK, Eckhardt LL, Grady KL, Hargraves IG, True Hills M, Kalscheur MM, Kramer DB, Kunneman M, Lampert R, Langford AT, Lewis KB, Lu Y, Mandrola JM, Martinez K, Matlock DD, McCarthy SR, Montori VM, Noseworthy PA, Orland KM, Ozanne E, Passman R, Pundi K, Roden DM, Saarel EV, Schmidt MM, Sears SF, Stacey D, Stafford RS, Steinberg BA, Youn Wass S, Wright JM.
PMID: 34865518
Circ Arrhythm Electrophysiol. 2021 Dec;14(12):e007958. doi: 10.1161/CIRCEP.121.007958. Epub 2021 Dec 06.

Shared decision making (SDM) has been advocated to improve patient care, patient decision acceptance, patient-provider communication, patient motivation, adherence, and patient reported outcomes. Documentation of SDM is endorsed in several society guidelines and is a condition of reimbursement for...

Shared Decision Making in Cardiac Electrophysiology Procedures and Arrhythmia Management.

Circulation. Arrhythmia and electrophysiology

Chung MK, Fagerlin A, Wang PJ, Ajayi TB, Allen LA, Baykaner T, Benjamin EJ, Branda M, Cavanaugh KL, Chen LY, Crossley GH, Delaney RK, Eckhardt LL, Grady KL, Hargraves IG, True Hills M, Kalscheur MM, Kramer DB, Kunneman M, Lampert R, Langford AT, Lewis KB, Lu Y, Mandrola JM, Martinez K, Matlock DD, McCarthy SR, Montori VM, Noseworthy PA, Orland KM, Ozanne E, Passman R, Pundi K, Roden DM, Saarel EV, Schmidt MM, Sears SF, Stacey D, Stafford RS, Steinberg BA, Youn Wass S, Wright JM.
PMID: 34865518
Circ Arrhythm Electrophysiol. 2021 Dec;14(12):e007958. doi: 10.1161/CIRCEP.121.007958. Epub 2021 Dec 06.

Shared decision making (SDM) has been advocated to improve patient care, patient decision acceptance, patient-provider communication, patient motivation, adherence, and patient reported outcomes. Documentation of SDM is endorsed in several society guidelines and is a condition of reimbursement for...

Long-Term Relapse-Free Survival by Interdisciplinary Collaboration in a Patient with Metastatic Pancreatic Cancer (UICC IV).

Case reports in oncology

Roehrig S, Wein A, Albrecht H, Maennlein G, Wolff K, Muskoski D, Amann K, Janka R, Hohenberger W, Hahn EG, Siebler J, Neurath MF, Boxberger F.
PMID: 21941491
Case Rep Oncol. 2011 May;4(2):413-9. doi: 10.1159/000331239. Epub 2011 Aug 24.

INTRODUCTION: The prognostic outlook for patients suffering from pancreatic cancer is generally poor. Particularly in cases of advanced and metastatic disease, long-term relapse-free survival may be achieved only in a few cases.CASE REPORT: A 45-year-old patient presented with metastatic...

Increased Collagen Crosslinking in Stiff Clubfoot Tissue: Implications for the Improvement of Therapeutic Strategies.

International journal of molecular sciences

Knitlova J, Doubkova M, Eckhardt A, Ostadal M, Musilkova J, Bacakova L, Novotny T.
PMID: 34769331
Int J Mol Sci. 2021 Nov 02;22(21). doi: 10.3390/ijms222111903.

Congenital clubfoot is a complex musculoskeletal deformity, in which a stiff, contracted tissue forms in the medial part of the foot. Fibrotic changes are associated with increased collagen deposition and lysyl oxidase (LOX)-mediated crosslinking, which impair collagen degradation and...

Anticoagulation, therapy of concomitant conditions, and early rhythm control therapy: a detailed analysis of treatment patterns in the EAST - AFNET 4 trial.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Metzner A, Suling A, Brandes A, Breithardt G, Camm AJ, Crijns HJGM, Eckardt L, Elvan A, Goette A, Haegeli LM, Heidbuchel H, Kautzner J, Kuck KH, Mont L, Ng AA, Szumowski L, Themistoclakis S, van Gelder IC, Vardas P, Wegscheider K, Willems S, Kirchhof P.
PMID: 34473249
Europace. 2021 Sep 02; doi: 10.1093/europace/euab200. Epub 2021 Sep 02.

AIMS: Treatment patterns were compared between randomized groups in EAST-AFNET 4 to assess whether differences in anticoagulation, therapy of concomitant diseases, or intensity of care can explain the clinical benefit achieved with early rhythm control in EAST-AFNET 4.METHODS AND...

Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S).

Critical care medicine

van Sleuwen M, Sun H, Eckhardt C, Neelagiri A, Tesh RA, Westmeijer M, Paixao L, Rajan S, Velpula Krishnamurthy P, Sikka P, Leone MJ, Panneerselvam E, Quadri SA, Akeju O, Kimchi EY, Westover MB.
PMID: 34582420
Crit Care Med. 2022 Jan 01;50(1):e11-e19. doi: 10.1097/CCM.0000000000005224.

OBJECTIVES: Delirium is a common and frequently underdiagnosed complication in acutely hospitalized patients, and its severity is associated with worse clinical outcomes. We propose a physiologically based method to quantify delirium severity as a tool that can help close...

Enhancing the Heterologous Fructosyltransferase Activity of .

Frontiers in bioengineering and biotechnology

Burghardt JP, Fan R, Baas M, Eckhardt D, Gerlach D, Czermak P.
PMID: 33324627
Front Bioeng Biotechnol. 2020 Nov 25;8:607507. doi: 10.3389/fbioe.2020.607507. eCollection 2020.

The enzymatic production of prebiotic fructo-oligosaccharides (FOS) from sucrose involves fructosyltransferases (FFTs) and invertases, both of which catalyze forward (transferase) and reverse (hydrolysis) reactions. FOS yields can therefore be increased by favoring the forward reaction. We investigated process conditions...

Early Rhythm Control Therapy in Patients With Atrial Fibrillation and Heart Failure.

Circulation

Rillig A, Magnussen C, Ozga AK, Suling A, Brandes A, Breithardt G, Camm AJ, Crijns HJGM, Eckardt L, Elvan A, Goette A, Gulizia M, Haegeli L, Heidbuchel H, Kuck KH, Ng A, Szumowski L, van Gelder I, Wegscheider K, Kirchhof P.
PMID: 34328366
Circulation. 2021 Sep 14;144(11):845-858. doi: 10.1161/CIRCULATIONAHA.121.056323. Epub 2021 Jul 30.

BACKGROUND: Even on optimal therapy, many patients with heart failure and atrial fibrillation experience cardiovascular complications. Additional treatments are needed to reduce these events, especially in patients with heart failure and preserved left ventricular ejection fraction.METHODS: This prespecified subanalysis...

Showing 397 to 406 of 406 entries