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Showing 25 to 36 of 149 entries
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Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue.

Cancers

Gholiha AR, Hollander P, Löf L, Larsson A, Hashemi J, Ulfstedt JM, Molin D, Amini RM, Freyhult E, Kamali-Moghaddam M, Enblad G.
PMID: 35008176
Cancers (Basel). 2021 Dec 21;14(1). doi: 10.3390/cancers14010009.

In classical Hodgkin Lymphoma (cHL), immunoediting via protein signaling is key to evading tumor surveillance. We aimed to identify immune-related proteins that distinguish diagnostic cHL tissues (=diagnostic tumor lysates,

Development of a highly specific and sensitive VHH-based sandwich immunoassay for the detection of the SARS-CoV-2 nucleoprotein.

The Journal of biological chemistry

Gransagne M, Aymé G, Brier S, Chauveau-Le Friec G, Meriaux V, Nowakowski M, Dejardin F, Levallois S, Dias de Melo G, Donati F, Prot M, Brûlé S, Raynal B, Bellalou J, Goncalves P, Montagutelli X, Di Santo JP, Lazarini F, England P, Petres S, Escriou N, Lafaye P.
PMID: 34678315
J Biol Chem. 2021 Oct 20;298(1):101290. doi: 10.1016/j.jbc.2021.101290. Epub 2021 Oct 20.

The current COVID-19 pandemic illustrates the importance of obtaining reliable methods for the rapid detection of SARS-CoV-2. A highly specific and sensitive diagnostic test able to differentiate the SARS-CoV-2 virus from common human coronaviruses is therefore needed. Coronavirus nucleoprotein...

Incidence of Non-Syndromic and Syndromic Craniosynostosis in Sweden.

The Journal of craniofacial surgery

Tarnow P, Kölby L, Maltese G, Söfteland MB, Lewén A, Nilsson P, Enblad P, Nowinski D.
PMID: 35025825
J Craniofac Surg. 2022 Jan 12; doi: 10.1097/SCS.0000000000008457. Epub 2022 Jan 12.

ABSTRACT: Premature craniosynostosis is a rare condition, with a wide range of incidence estimations in the literature. The aim of this study was to establish the current incidence among the Swedish population. Since the surgical care for these children...

Cerebral Pressure Autoregulation in Brain Injury and Disorders-A Review on Monitoring, Management, and Future Directions.

World neurosurgery

Svedung Wettervik T, Fahlström M, Enblad P, Lewén A.
PMID: 34775084
World Neurosurg. 2021 Nov 11;158:118-131. doi: 10.1016/j.wneu.2021.11.027. Epub 2021 Nov 11.

The role of cerebral pressure autoregulation (CPA) in brain injury and disorders has gained increased interest. The CPA is often disturbed as a consequence of acute brain injury, which contributes to further brain damage and worse outcome. Specifically, in...

The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.

Cell

Sharma A, Zhang X, Dejnirattisai W, Dai X, Gong D, Wongwiwat W, Duquerroy S, Rouvinski A, Vaney MC, Guardado-Calvo P, Haouz A, England P, Sun R, Zhou ZH, Mongkolsapaya J, Screaton GR, Rey FA.
PMID: 34852239
Cell. 2021 Dec 09;184(25):6052-6066.e18. doi: 10.1016/j.cell.2021.11.010. Epub 2021 Nov 30.

The human monoclonal antibody C10 exhibits extraordinary cross-reactivity, potently neutralizing Zika virus (ZIKV) and the four serotypes of dengue virus (DENV1-DENV4). Here we describe a comparative structure-function analysis of C10 bound to the envelope (E) protein dimers of the...

Oecologia

Ekblad A, Nyberg G, Högberg P.
PMID: 28547692
Oecologia. 2002 Apr;131(2):245-249. doi: 10.1007/s00442-002-0869-9. Epub 2002 Apr 01.

We tested whether

High proportions of PD-1.

Blood advances

Hollander P, Kamper P, Smedby KE, Enblad G, Ludvigsen M, Mortensen J, Amini RM, Hamilton-Dutoit S, d'Amore F, Molin D, Glimelius I.
PMID: 29296784
Blood Adv. 2017 Aug 08;1(18):1427-1439. doi: 10.1182/bloodadvances.2017006346. eCollection 2017 Aug 08.

Immune checkpoint inhibition targeting the programmed death receptor (PD)-1 pathway is a novel treatment approach in relapsed and refractory classical Hodgkin lymphoma (cHL). Identifying patients with a high risk of treatment failure could support the use of PD-1 inhibitors...

To Increase Mental Health Literacy and Human Rights Among New-Coming, Low-Educated Mothers With Experience of War: A Culturally, Tailor-Made Group Health Promotion Intervention With Participatory Methodology Addressing Indirectly the Children.

Frontiers in psychiatry

Ekblad S.
PMID: 32733291
Front Psychiatry. 2020 Jul 08;11:611. doi: 10.3389/fpsyt.2020.00611. eCollection 2020.

Due to the increasing numbers of newcomers with impacts of war, civil war and persecution, at high risk of trauma-related mental health problems, there is a need for increase the poor mental health literacy (MHL) and human rights among...

Physical Interactions and Expression Quantitative Traits Loci Identify Regulatory Connections for Obesity and Type 2 Diabetes Associated SNPs.

Frontiers in genetics

Fadason T, Ekblad C, Ingram JR, Schierding WS, O'Sullivan JM.
PMID: 29081791
Front Genet. 2017 Oct 13;8:150. doi: 10.3389/fgene.2017.00150. eCollection 2017.

The mechanisms that underlie the association between obesity and type 2 diabetes are not fully understood. Here, we investigated the role of the 3D genome organization in the pathogeneses of obesity and type-2 diabetes. We interpreted the combined and...

Medical and licit drug use in an urban/rural study population with a refugee background, 7-8 years into resettlement.

Psycho-social medicine

Johansson Blight K, Persson JO, Ekblad S, Ekberg J.
PMID: 19742286
Psychosoc Med. 2008 Apr 23;5:Doc04.

OBJECTIVE: Research into medical and licit drug use in resettled refugee populations is scarce, despite the fact that mental health status often has been found to be poorer than in general populations. Hence the aim of this study was...

Comparison of metformin and insulin in the treatment of gestational diabetes: a retrospective, case-control study.

The review of diabetic studies : RDS

Tertti K, Ekblad U, Vahlberg T, Rönnemaa T.
PMID: 18795211
Rev Diabet Stud. 2008;5(2):95-101. doi: 10.1900/RDS.2008.5.95. Epub 2008 Aug 10.

OBJECTIVES: Limited data are available on metformin therapy in gestational diabetes. The aim of the study was to compare maternal and neonatal outcomes in patients with gestational diabetes mellitus (GDM) treated with metformin with those treated with insulin, or...

Erratum: Structural basis of potent Zika-dengue virus antibody cross-neutralization.

Nature

Barba-Spaeth G, Dejnirattisai W, Rouvinski A, Vaney MC, Medits I, Sharma A, Simon-Lorière E, Sakuntabhai A, Cao-Lormeau VM, Haouz A, England P, Stiasny K, Mongkolsapaya J, Heinz FX, Screaton GR, Rey FA.
PMID: 27626374
Nature. 2016 Nov 10;539(7628):314. doi: 10.1038/nature19780. Epub 2016 Sep 14.

No abstract available.

Showing 25 to 36 of 149 entries