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Showing 25 to 36 of 142 entries
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The onco-immunological implications of Fusobacterium nucleatum in breast cancer.

Immunology letters

Van der Merwe M, Van Niekerk G, Botha A, Engelbrecht AM.
PMID: 33647328
Immunol Lett. 2021 Apr;232:60-66. doi: 10.1016/j.imlet.2021.02.007. Epub 2021 Feb 26.

Breast cancer is a leading cause of death worldwide and a better understanding of this disease is needed to improve treatment outcomes. Recent evidence indicates that bacterial dysbiosis is associated with breast cancer, but the bacteria involved remain poorly...

Theoretical and Experimental Study of the Excess Thermodynamic Properties of Highly Nonideal Liquid Mixtures of Butanol Isomers + DBE.

The journal of physical chemistry. B

Engelbrecht LV, Farris R, Vasiliu T, Demurtas M, Piras A, Cesare Marincola F, Laaksonen A, Porcedda S, Mocci F.
PMID: 33428423
J Phys Chem B. 2021 Jan 21;125(2):587-600. doi: 10.1021/acs.jpcb.0c10076. Epub 2021 Jan 11.

Binary alcohol + ether liquid mixtures are of significant importance as potential biofuels or additives for internal combustion engines and attract considerable fundamental interest as model systems containing one strongly H-bonded self-associating component (alcohol) and one that is unable...

Stereodivergent Nitrocyclopropane Formation during Biosynthesis of Belactosins and Hormaomycins.

Journal of the American Chemical Society

Shimo S, Ushimaru R, Engelbrecht A, Harada M, Miyamoto K, Kulik A, Uchiyama M, Kaysser L, Abe I, Chapman RS.
PMID: 34710328
J Am Chem Soc. 2021 Nov 10;143(44):18413-18418. doi: 10.1021/jacs.1c10201. Epub 2021 Oct 28.

Belactosins and hormaomycins are peptide natural products containing 3-(2-aminocyclopropyl)alanine and 3-(2-nitrocyclopropyl)alanine residues, respectively, with opposite stereoconfigurations of the cyclopropane ring. Herein we demonstrate that the heme oxygenase-like enzymes BelK and HrmI catalyze the N-oxygenation of l-lysine to generate 6-nitronorleucine....

Test for Covid-19 seasonality and the risk of second waves.

One health (Amsterdam, Netherlands)

Engelbrecht FA, Scholes RJ.
PMID: 33283035
One Health. 2021 Jun;12:100202. doi: 10.1016/j.onehlt.2020.100202. Epub 2020 Nov 29.

Ten months into the Covid-19 pandemic it remains unclear whether transmission of SARS-CoV-2 is affected by climate factors. Using a dynamic epidemiological model with Covid-19 climate sensitivity in the likely range, we demonstrate why attempts to detect a climate...

Rethinking the Plant Economics Spectrum for Annuals: A Multi-Species Study.

Frontiers in plant science

Kurze S, Engelbrecht BMJ, Bilton MC, Tielbörger K, Álvarez-Cansino L.
PMID: 33841468
Front Plant Sci. 2021 Mar 26;12:640862. doi: 10.3389/fpls.2021.640862. eCollection 2021.

The plant economics spectrum hypothesizes a correlation among resource-use related traits along one single axis, which determines species' growth rates and their ecological filtering along resource gradients. This concept has been mostly investigated and shown in perennial species, but...

Amino Acid Starvation Sensitizes Resistant Breast Cancer to Doxorubicin-Induced Cell Death.

Frontiers in cell and developmental biology

Thomas M, Davis T, Nell T, Sishi B, Engelbrecht AM.
PMID: 33178685
Front Cell Dev Biol. 2020 Oct 15;8:565915. doi: 10.3389/fcell.2020.565915. eCollection 2020.

Many clinical trials are beginning to assess the effectiveness of compounds known to regulate autophagy in patients receiving anti-cancer chemotherapy. However, autophagy inhibition, through exogenous inhibitors, or activation, through starvation, has revealed conflicting roles in cancer management and chemotherapeutic...

Case Report: Safe Tourniquet Removal in Black Mamba (Dendroaspis polylepis) Bites.

The American journal of tropical medicine and hygiene

Pelle RP, Engelbrecht A, Lalloo V.
PMID: 34724630
Am J Trop Med Hyg. 2021 Nov 01;106(1):338-341. doi: 10.4269/ajtmh.21-0374.

The black mamba is known for its notorious potent neurotoxic venom. For this reason, their bites are often erroneously treated in the field with the application of a tourniquet in the hope of delaying systemic spread of the venom....

Endothelial-Specific Loss of Sphingosine-1-Phosphate Receptor 1 Increases Vascular Permeability and Exacerbates Bleomycin-Induced Pulmonary Fibrosis.

American journal of respiratory cell and molecular biology

Knipe RS, Spinney JJ, Abe EA, Probst CK, Franklin A, Logue A, Giacona F, Drummond M, Griffith J, Brazee PL, Hariri LP, Montesi SB, Black KE, Hla T, Kuo A, Cartier A, Engelbrecht E, Christoffersen C, Shea BS, Tager AM, Medoff BD.
PMID: 34343038
Am J Respir Cell Mol Biol. 2021 Aug 03; doi: 10.1165/rcmb.2020-0408OC. Epub 2021 Aug 03.

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease which leads to significant morbidity and mortality from respiratory failure. The two drugs currently approved for clinical use slow the rate of decline in lung function but have not been...

Enhanced Therapeutic Efficacy in Cancer Patients by Short-term Fasting: The Autophagy Connection.

Frontiers in oncology

van Niekerk G, Hattingh SM, Engelbrecht AM.
PMID: 27896219
Front Oncol. 2016 Nov 14;6:242. doi: 10.3389/fonc.2016.00242. eCollection 2016.

Preclinical studies suggest that fasting prior to chemotherapy may be an effective strategy to protect patients against the adverse effects of chemo-toxicity. Fasting may also sensitize cancer cells to chemotherapy. It is further suggested that fasting may similarly augment...

A case report of detecting subclinical coagulopathy in a patient with boomslang (Dipholidus typus) bite.

South African family practice : official journal of the South African Academy of Family Practice/Primary Care

Tambwe MJ, Lalloo V, Engelbrecht A, Pelle P.
PMID: 34476966
S Afr Fam Pract (2004). 2021 Aug 11;63(1):e1-e5. doi: 10.4102/safp.v63i1.5299.

The boomslang (Dipholidus typus) has a predominantly haemotoxic venom. Because of the consumptive nature of the coagulopathy, signs and symptoms are usually delayed by up to 72 h after the bite. Traditional laboratory coagulation assays have a long turnaround...

Ellipsometric investigation of rough zinc arsenide epilayers.

Applied optics

Brink DJ, Engelbrecht JA.
PMID: 11936787
Appl Opt. 2002 Apr 01;41(10):1894-8. doi: 10.1364/ao.41.001894.

We report single-wavelength ellipsometric measurements of the complex index of refraction of rough Zn3As2 films on InP substrates. What we believe to be a novel technique, based on surface roughness measurements by atomic-force microscopy, is discussed to extract useful...

[CME in Germany--the voluntary CME-certification of the Chambers of Physicians].

Deutsche medizinische Wochenschrift (1946)

Eckel H, Engelbrecht J.
PMID: 12673534
Dtsch Med Wochenschr. 2003 Apr 04;128(14):757-8. doi: 10.1055/s-2003-38421.

No abstract available.

Showing 25 to 36 of 142 entries