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Showing 409 to 418 of 418 entries
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Detecting Corticospinal Tract Impairment in Tumor Patients With Fiber Density and Tensor-Based Metrics.

Frontiers in oncology

Fekonja LS, Wang Z, Aydogan DB, Roine T, Engelhardt M, Dreyer FR, Vajkoczy P, Picht T.
PMID: 33585250
Front Oncol. 2021 Jan 27;10:622358. doi: 10.3389/fonc.2020.622358. eCollection 2020.

Tumors infiltrating the motor system lead to significant disability, often caused by corticospinal tract injury. The delineation of the healthy-pathological white matter (WM) interface area, for which diffusion magnetic resonance imaging (dMRI) has shown promising potential, may improve treatment...

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Fekonja LS, Wang Z, Aydogan DB, et al. Detecting Corticospinal Tract Impairment in Tumor Patients With Fiber Density and Tensor-Based Metrics. Front Oncol. 2021;10:622358doi: 10.3389/fonc.2020.622358.
Fekonja, L. S., Wang, Z., Aydogan, D. B., Roine, T., Engelhardt, M., Dreyer, F. R., Vajkoczy, P., & Picht, T. (2020). Detecting Corticospinal Tract Impairment in Tumor Patients With Fiber Density and Tensor-Based Metrics. Frontiers in oncology, 10622358. https://doi.org/10.3389/fonc.2020.622358
Fekonja, Lucius S, et al. "Detecting Corticospinal Tract Impairment in Tumor Patients With Fiber Density and Tensor-Based Metrics." Frontiers in oncology vol. 10 (2020): 622358. doi: https://doi.org/10.3389/fonc.2020.622358
Fekonja LS, Wang Z, Aydogan DB, Roine T, Engelhardt M, Dreyer FR, Vajkoczy P, Picht T. Detecting Corticospinal Tract Impairment in Tumor Patients With Fiber Density and Tensor-Based Metrics. Front Oncol. 2021 Jan 27;10:622358. doi: 10.3389/fonc.2020.622358. eCollection 2020. PMID: 33585250; PMCID: PMC7873606.
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MicroRNA-21-Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload.

Circulation

Ramanujam D, Schön AP, Beck C, Vaccarello P, Felician G, Dueck A, Esfandyari D, Meister G, Meitinger T, Schulz C, Engelhardt S.
PMID: 33550817
Circulation. 2021 Apr 13;143(15):1513-1525. doi: 10.1161/CIRCULATIONAHA.120.050682. Epub 2021 Feb 08.

BACKGROUND: Cardiac macrophages (cMPs) are increasingly recognized as important regulators of myocardial homeostasis and disease, yet the role of noncoding RNA in these cells is largely unknown. Small RNA sequencing of the entire miRNomes of the major cardiac cell...

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Ramanujam D, Schön AP, Beck C, et al. MicroRNA-21-Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload. Circulation. 2021;143(15):1513-1525doi: 10.1161/CIRCULATIONAHA.120.050682.
Ramanujam, D., Schön, A. P., Beck, C., Vaccarello, P., Felician, G., Dueck, A., Esfandyari, D., Meister, G., Meitinger, T., Schulz, C., & Engelhardt, S. (2021). MicroRNA-21-Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload. Circulation, 143(15), 1513-1525. https://doi.org/10.1161/CIRCULATIONAHA.120.050682
Ramanujam, Deepak, et al. "MicroRNA-21-Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload." Circulation vol. 143,15 (2021): 1513-1525. doi: https://doi.org/10.1161/CIRCULATIONAHA.120.050682
Ramanujam D, Schön AP, Beck C, Vaccarello P, Felician G, Dueck A, Esfandyari D, Meister G, Meitinger T, Schulz C, Engelhardt S. MicroRNA-21-Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload. Circulation. 2021 Apr 13;143(15):1513-1525. doi: 10.1161/CIRCULATIONAHA.120.050682. Epub 2021 Feb 08. PMID: 33550817; PMCID: PMC8032214.
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Frequent FGFR1 hotspot alterations in driver-unknown low-grade glioma and mixed neuronal-glial tumors.

Journal of cancer research and clinical oncology

Engelhardt S, Behling F, Beschorner R, Eckert F, Kohlhof P, Tatagiba M, Tabatabai G, Schuhmann MU, Ebinger M, Schittenhelm J.
PMID: 35018490
J Cancer Res Clin Oncol. 2022 Jan 11; doi: 10.1007/s00432-021-03906-x. Epub 2022 Jan 11.

PURPOSE: Low-grade gliomas (LGG) and mixed neuronal-glial tumors (MNGT) show frequent MAPK pathway alterations. Oncogenic fibroblast growth factor receptor 1 (FGFR1) tyrosinase kinase domain has been reported in brain tumors of various histologies. We sought to determine the frequency...

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Engelhardt S, Behling F, Beschorner R, et al. Frequent FGFR1 hotspot alterations in driver-unknown low-grade glioma and mixed neuronal-glial tumors. J Cancer Res Clin Oncol. 2022;doi: 10.1007/s00432-021-03906-x.
Engelhardt, S., Behling, F., Beschorner, R., Eckert, F., Kohlhof, P., Tatagiba, M., Tabatabai, G., Schuhmann, M. U., Ebinger, M., & Schittenhelm, J. (2022). Frequent FGFR1 hotspot alterations in driver-unknown low-grade glioma and mixed neuronal-glial tumors. Journal of cancer research and clinical oncology, . https://doi.org/10.1007/s00432-021-03906-x
Engelhardt, Sophie, et al. "Frequent FGFR1 hotspot alterations in driver-unknown low-grade glioma and mixed neuronal-glial tumors." Journal of cancer research and clinical oncology vol. (2022). doi: https://doi.org/10.1007/s00432-021-03906-x
Engelhardt S, Behling F, Beschorner R, Eckert F, Kohlhof P, Tatagiba M, Tabatabai G, Schuhmann MU, Ebinger M, Schittenhelm J. Frequent FGFR1 hotspot alterations in driver-unknown low-grade glioma and mixed neuronal-glial tumors. J Cancer Res Clin Oncol. 2022 Jan 11; doi: 10.1007/s00432-021-03906-x. Epub 2022 Jan 11. PMID: 35018490.
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Nano-scale architecture of blood-brain barrier tight-junctions.

eLife

Sasson E, Anzi S, Bell B, Yakovian O, Zorsky M, Deutsch U, Engelhardt B, Sherman E, Vatine G, Dzikowski R, Ben-Zvi A.
PMID: 34951586
Elife. 2021 Dec 24;10. doi: 10.7554/eLife.63253.

Tight junctions (TJs) between blood-brain barrier (BBB) endothelial cells construct a robust physical barrier, whose damage underlies BBB dysfunctions related to several neurodegenerative diseases. What makes these highly specialized BBB-TJs extremely restrictive remains unknown. Here, we use super-resolution microscopy...

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Sasson E, Anzi S, Bell B, et al. Nano-scale architecture of blood-brain barrier tight-junctions. Elife. 2021;10doi: 10.7554/eLife.63253.
Sasson, E., Anzi, S., Bell, B., Yakovian, O., Zorsky, M., Deutsch, U., Engelhardt, B., Sherman, E., Vatine, G., Dzikowski, R., & Ben-Zvi, A. (2021). Nano-scale architecture of blood-brain barrier tight-junctions. eLife, 10. https://doi.org/10.7554/eLife.63253
Sasson, Esther, et al. "Nano-scale architecture of blood-brain barrier tight-junctions." eLife vol. 10 (2021). doi: https://doi.org/10.7554/eLife.63253
Sasson E, Anzi S, Bell B, Yakovian O, Zorsky M, Deutsch U, Engelhardt B, Sherman E, Vatine G, Dzikowski R, Ben-Zvi A. Nano-scale architecture of blood-brain barrier tight-junctions. Elife. 2021 Dec 24;10. doi: 10.7554/eLife.63253. PMID: 34951586.
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A self-exciting point process to study multicellular spatial signaling patterns.

Proceedings of the National Academy of Sciences of the United States of America

Verma A, Jena SG, Isakov DR, Aoki K, Toettcher JE, Engelhardt BE.
PMID: 34362843
Proc Natl Acad Sci U S A. 2021 Aug 10;118(32). doi: 10.1073/pnas.2026123118.

Multicellular organisms rely on spatial signaling among cells to drive their organization, development, and response to stimuli. Several models have been proposed to capture the behavior of spatial signaling in multicellular systems, but existing approaches fail to capture both...

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Verma A, Jena SG, Isakov DR, et al. A self-exciting point process to study multicellular spatial signaling patterns. Proc Natl Acad Sci U S A. 2021;118(32)doi: 10.1073/pnas.2026123118.
Verma, A., Jena, S. G., Isakov, D. R., Aoki, K., Toettcher, J. E., & Engelhardt, B. E. (2021). A self-exciting point process to study multicellular spatial signaling patterns. Proceedings of the National Academy of Sciences of the United States of America, 118(32), . https://doi.org/10.1073/pnas.2026123118
Verma, Archit, et al. "A self-exciting point process to study multicellular spatial signaling patterns." Proceedings of the National Academy of Sciences of the United States of America vol. 118,32 (2021). doi: https://doi.org/10.1073/pnas.2026123118
Verma A, Jena SG, Isakov DR, Aoki K, Toettcher JE, Engelhardt BE. A self-exciting point process to study multicellular spatial signaling patterns. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32). doi: 10.1073/pnas.2026123118. PMID: 34362843; PMCID: PMC8364135.
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Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells.

eLife

Gastfriend BD, Nishihara H, Canfield SG, Foreman KL, Engelhardt B, Palecek SP, Shusta EV.
PMID: 34755601
Elife. 2021 Nov 10;10. doi: 10.7554/eLife.70992.

Endothelial cells (ECs) in the central nervous system (CNS) acquire their specialized blood-brain barrier (BBB) properties in response to extrinsic signals, with Wnt/β-catenin signaling coordinating multiple aspects of this process. Our knowledge of CNS EC development has been advanced...

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Gastfriend BD, Nishihara H, Canfield SG, et al. Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells. Elife. 2021;10doi: 10.7554/eLife.70992.
Gastfriend, B. D., Nishihara, H., Canfield, S. G., Foreman, K. L., Engelhardt, B., Palecek, S. P., & Shusta, E. V. (2021). Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells. eLife, 10. https://doi.org/10.7554/eLife.70992
Gastfriend, Benjamin D, et al. "Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells." eLife vol. 10 (2021). doi: https://doi.org/10.7554/eLife.70992
Gastfriend BD, Nishihara H, Canfield SG, Foreman KL, Engelhardt B, Palecek SP, Shusta EV. Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells. Elife. 2021 Nov 10;10. doi: 10.7554/eLife.70992. PMID: 34755601; PMCID: PMC8664294.
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Dynamical Symmetries and Symmetry-Protected Selection Rules in Periodically Driven Quantum Systems.

Physical review letters

Engelhardt G, Cao J.
PMID: 33750178
Phys Rev Lett. 2021 Mar 05;126(9):090601. doi: 10.1103/PhysRevLett.126.090601.

In recent experiments, the light-matter interaction has reached the ultrastrong coupling limit, which can give rise to dynamical generalizations of spatial symmetries in periodically driven systems. Here, we present a unified framework of dynamical-symmetry-protected selection rules based on Floquet...

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Engelhardt G, Cao J. Dynamical Symmetries and Symmetry-Protected Selection Rules in Periodically Driven Quantum Systems. Phys Rev Lett. 2021;126(9):090601doi: 10.1103/PhysRevLett.126.090601.
Engelhardt, G., & Cao, J. (2021). Dynamical Symmetries and Symmetry-Protected Selection Rules in Periodically Driven Quantum Systems. Physical review letters, 126(9), 090601. https://doi.org/10.1103/PhysRevLett.126.090601
Engelhardt, Georg, and Cao, Jianshu. "Dynamical Symmetries and Symmetry-Protected Selection Rules in Periodically Driven Quantum Systems." Physical review letters vol. 126,9 (2021): 090601. doi: https://doi.org/10.1103/PhysRevLett.126.090601
Engelhardt G, Cao J. Dynamical Symmetries and Symmetry-Protected Selection Rules in Periodically Driven Quantum Systems. Phys Rev Lett. 2021 Mar 05;126(9):090601. doi: 10.1103/PhysRevLett.126.090601. PMID: 33750178.
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Hierarchical Gaussian Processes and Mixtures of Experts to Model COVID-19 Patient Trajectories.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing

Cui S, Yoo EC, Li D, Laudanski K, Engelhardt BE.
PMID: 34890155
Pac Symp Biocomput. 2022;27:266-277.

Gaussian processes (GPs) are a versatile nonparametric model for nonlinear regression and have been widely used to study spatiotemporal phenomena. However, standard GPs offer limited interpretability and generalizability for datasets with naturally occurring hierarchies. With large-scale, rapidly-updating electronic health...

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Cui S, Yoo EC, Li D, et al. Hierarchical Gaussian Processes and Mixtures of Experts to Model COVID-19 Patient Trajectories. Pac Symp Biocomput. 2022;27:266-277
Cui, S., Yoo, E. C., Li, D., Laudanski, K., & Engelhardt, B. E. (2022). Hierarchical Gaussian Processes and Mixtures of Experts to Model COVID-19 Patient Trajectories. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 27266-277.
Cui, Sunny, et al. "Hierarchical Gaussian Processes and Mixtures of Experts to Model COVID-19 Patient Trajectories." Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing vol. 27 (2022): 266-277.
Cui S, Yoo EC, Li D, Laudanski K, Engelhardt BE. Hierarchical Gaussian Processes and Mixtures of Experts to Model COVID-19 Patient Trajectories. Pac Symp Biocomput. 2022;27:266-277. PMID: 34890155.
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Compliance With Vaccination Recommendations Among Patients With Multiple Myeloma: A Real World Experience.

HemaSphere

Ludwig H, Meckl A, Engelhardt M.
PMID: 34235399
Hemasphere. 2021 Jun 25;5(7):e597. doi: 10.1097/HS9.0000000000000597. eCollection 2021 Jul.

No abstract available.

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Ludwig H, Meckl A, Engelhardt M. Compliance With Vaccination Recommendations Among Patients With Multiple Myeloma: A Real World Experience. Hemasphere. 2021;5(7):e597doi: 10.1097/HS9.0000000000000597.
Ludwig, H., Meckl, A., & Engelhardt, M. (2021). Compliance With Vaccination Recommendations Among Patients With Multiple Myeloma: A Real World Experience. HemaSphere, 5(7), e597. https://doi.org/10.1097/HS9.0000000000000597
Ludwig, Heinz, et al. "Compliance With Vaccination Recommendations Among Patients With Multiple Myeloma: A Real World Experience." HemaSphere vol. 5,7 (2021): e597. doi: https://doi.org/10.1097/HS9.0000000000000597
Ludwig H, Meckl A, Engelhardt M. Compliance With Vaccination Recommendations Among Patients With Multiple Myeloma: A Real World Experience. Hemasphere. 2021 Jun 25;5(7):e597. doi: 10.1097/HS9.0000000000000597. eCollection 2021 Jul. PMID: 34235399; PMCID: PMC8232067.
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The blood-CSF-brain route of neurological disease: The indirect pathway into the brain.

Neuropathology and applied neurobiology

Cousins O, Hodges A, Schubert J, Veronese M, Turkheimer F, Miyan J, Engelhardt B, Roncaroli F.
PMID: 34935179
Neuropathol Appl Neurobiol. 2021 Dec 21;e12789. doi: 10.1111/nan.12789. Epub 2021 Dec 21.

The brain is protected by the endothelial blood-brain barrier (BBB) that limits the access of micro-organisms, tumour cells, immune cells and autoantibodies to the parenchyma. However, the classic model of disease spread across a disrupted BBB does not explain...

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Cousins O, Hodges A, Schubert J, et al. The blood-CSF-brain route of neurological disease: The indirect pathway into the brain. Neuropathol Appl Neurobiol. 2021;e12789doi: 10.1111/nan.12789.
Cousins, O., Hodges, A., Schubert, J., Veronese, M., Turkheimer, F., Miyan, J., Engelhardt, B., & Roncaroli, F. (2021). The blood-CSF-brain route of neurological disease: The indirect pathway into the brain. Neuropathology and applied neurobiology, e12789. https://doi.org/10.1111/nan.12789
Cousins, Oliver, et al. "The blood-CSF-brain route of neurological disease: The indirect pathway into the brain." Neuropathology and applied neurobiology vol. (2021): e12789. doi: https://doi.org/10.1111/nan.12789
Cousins O, Hodges A, Schubert J, Veronese M, Turkheimer F, Miyan J, Engelhardt B, Roncaroli F. The blood-CSF-brain route of neurological disease: The indirect pathway into the brain. Neuropathol Appl Neurobiol. 2021 Dec 21;e12789. doi: 10.1111/nan.12789. Epub 2021 Dec 21. PMID: 34935179.
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Showing 409 to 418 of 418 entries