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Showing 25 to 36 of 36 entries
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The plasma metabolome of Atlantic salmon as studied by .

Metabolomics : Official journal of the Metabolomic Society

Aru V, Khakimov B, Sørensen KM, Chikwati EM, Kortner TM, Midtlyng P, Krogdahl Å, Engelsen SB.
PMID: 33999285
Metabolomics. 2021 May 17;17(6):50. doi: 10.1007/s11306-021-01797-0.

INTRODUCTION: Metabolomics applications to the aquaculture research are increasing steadily. The use of standardized proton nuclear magnetic resonance (OBJECTIVE: Standard operating procedures developed for analysing (human) plasma by METHODS: A total of 72 salmon were collected from three aquaculture...

Adaptive mechanisms of resistance to anti-neoplastic agents.

MedChemComm

Ferreira BI, Lie MK, Engelsen AST, Machado S, Link W, Lorens JB.
PMID: 30108690
Medchemcomm. 2016 Oct 21;8(1):53-66. doi: 10.1039/c6md00394j. eCollection 2017 Jan 01.

Intrinsic and acquired resistance to conventional and targeted therapeutics is a fundamental reason for treatment failure in many cancer patients. Targeted approaches to overcome chemoresistance as well as resistance to targeted approaches require in depth understanding of the underlying...

Human Fecal Metabolome Reflects Differences in Body Mass Index, Physical Fitness, and Blood Lipoproteins in Healthy Older Adults.

Metabolites

Cui M, Trimigno A, Castro-Mejía JL, Reitelseder S, Bülow J, Bechshøft RL, Nielsen DS, Holm L, Engelsen SB, Khakimov B.
PMID: 34822375
Metabolites. 2021 Oct 21;11(11). doi: 10.3390/metabo11110717.

This study investigated how body mass index (BMI), physical fitness, and blood plasma lipoprotein levels are related to the fecal metabolome in older adults. The fecal metabolome data were acquired using proton nuclear magnetic resonance spectroscopy and gas chromatography-mass...

Data on the changes of the mussels׳ metabolic profile under different cold storage conditions.

Data in brief

Aru V, Pisano MB, Savorani F, Engelsen SB, Cosentino S, Cesare Marincola F.
PMID: 27081673
Data Brief. 2016 Mar 19;7:951-7. doi: 10.1016/j.dib.2016.03.051. eCollection 2016 Jun.

One of the main problems of seafood marketing is the ease with which fish and shellfish undergo deterioration after death. (1)H NMR spectroscopy and microbiological analysis were applied to get in depth insight into the effects of cold storage...

Induction of alveolar and bronchiolar phenotypes in human lung organoids.

Physiological reports

Hoareau L, Engelsen AST, Aanerud M, Ramnefjell MP, Salminen PR, Gärtner F, Halvorsen T, Raeder H, Bentsen MHL.
PMID: 34110705
Physiol Rep. 2021 Jun;9(11):e14857. doi: 10.14814/phy2.14857.

Patient-derived organoids have revolutionized biomedical research and therapies by "transferring the patient into the Petri dish". In vitro access to human lung organoids representing distal lung tissue, i.e. alveolar organoids, would facilitate research pertaining to a wide range of...

Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival.

Cancers

Zaarour RF, Azakir B, Hajam EY, Nawafleh H, Zeinelabdin NA, Engelsen AST, Thiery J, Jamora C, Chouaib S.
PMID: 33573362
Cancers (Basel). 2021 Jan 30;13(3). doi: 10.3390/cancers13030533.

Programmed cell death or type I apoptosis has been extensively studied and its contribution to the pathogenesis of disease is well established. However, autophagy functions together with apoptosis to determine the overall fate of the cell. The cross talk...

Light scattering and light absorbance separated by extended multiplicative signal correction. application to near-infrared transmission analysis of powder mixtures.

Analytical chemistry

Martens H, Nielsen JP, Engelsen SB.
PMID: 12585463
Anal Chem. 2003 Feb 01;75(3):394-404. doi: 10.1021/ac020194w.

The extended multiplicative signal correction (EMSC) preprocessing method allows a separation of physical light-scattering effects from chemical (vibrational) light absorbance effects in spectra from, for example, powders or turbid solutions. It is here applied to diffuse near infrared transmission...

Forecasting individual breast cancer risk using plasma metabolomics and biocontours.

Metabolomics : Official journal of the Metabolomic Society

Bro R, Kamstrup-Nielsen MH, Engelsen SB, Savorani F, Rasmussen MA, Hansen L, Olsen A, Tjønneland A, Dragsted LO.
PMID: 26366139
Metabolomics. 2015;11(5):1376-1380. doi: 10.1007/s11306-015-0793-8. Epub 2015 Mar 10.

Breast cancer is a major cause of death for women. To improve treatment, current oncology research focuses on discovering and validating new biomarkers for early detection of cancer; so far with limited success. Metabolic profiling of plasma samples and...

Prediction of water-holding capacity and composition of porcine meat by comparative spectroscopy.

Meat science

Brøndum J, Munck L, Henckel P, Karlsson A, Tornberg E, Engelsen SB.
PMID: 22061083
Meat Sci. 2000 Jun;55(2):177-85. doi: 10.1016/s0309-1740(99)00141-2.

Four spectroscopic instruments, a fibre optical probe (FOP), a visual (VIS) and near infrared (NIR) reflectance spectrophotometer, a reflectance spectrofluorometer and a low-field (1)H nuclear magnetic resonance (LF-NMR) instrument were used to perform measurements on two muscles (longissimus dorsi...

Monitoring of the Rioja red wine production process by .

Journal of the science of food and agriculture

López-Rituerto E, Sørensen KM, Savorani F, Engelsen SB, Avenoza A, Peregrina JM, Busto JH.
PMID: 34921687
J Sci Food Agric. 2021 Dec 18; doi: 10.1002/jsfa.11729. Epub 2021 Dec 18.

BACKGROUND: As an inherently quantitative and unbiased analytical technique, proton nuclear magnetic resonance (RESULTS: By using NMR, it is possible to monitor quantitative changes in wine metabolites (amino acids, organic acids and some phenolic compounds) during the winemaking process,...

Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance.

Frontiers in cell and developmental biology

Jokela TA, Engelsen AST, Rybicka A, Pelissier Vatter FA, Garbe JC, Miyano M, Tiron C, Ferariu D, Akslen LA, Stampfer MR, Lorens JB, LaBarge MA.
PMID: 29719832
Front Cell Dev Biol. 2018 Apr 17;6:41. doi: 10.3389/fcell.2018.00041. eCollection 2018.

The existence of rare cancer cells that sporadically acquire drug-tolerance through epigenetic mechanisms is proposed as one mechanism that drives cancer therapy failure. Here we provide evidence that specific microenvironments impose non-sporadic expression of proteins related to epithelial plasticity...

Plasma Metabolomics to Evaluate Progression of Necrotising Enterocolitis in Preterm Pigs.

Metabolites

Jiang YN, Ye YX, Sangild PT, Thymann T, Engelsen SB, Khakimov B, Jiang PP.
PMID: 33946896
Metabolites. 2021 Apr 29;11(5). doi: 10.3390/metabo11050283.

Necrotising enterocolitis (NEC) is a microbiome-dependent gut disease in preterm infants in early life. Antibiotic treatment is a common intervention for NEC. How NEC lesions, with or without antibiotics, affect plasma metabolome was explored in this study. Formula-fed preterm...

Showing 25 to 36 of 36 entries