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Showing 13 to 24 of 56 entries
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A pair of new oxindole alkaloids isolated from .

Natural product research

Liang XX, Yang JX, Li JM, Huang JB, Yang LM, Sun TT, Luo RH, Xiao WL, Zheng YT, Li XL, Nesdale D.
PMID: 34738856
Nat Prod Res. 2021 Nov 05;1-7. doi: 10.1080/14786419.2021.2000982. Epub 2021 Nov 05.

A pair of new oxindole alkaloids, named macrophyllines C (

Late Quaternary dynamics of Arctic biota from ancient environmental genomics.

Nature

Wang Y, Pedersen MW, Alsos IG, De Sanctis B, Racimo F, Prohaska A, Coissac E, Owens HL, Merkel MKF, Fernandez-Guerra A, Rouillard A, Lammers Y, Alberti A, Denoeud F, Money D, Ruter AH, McColl H, Larsen NK, Cherezova AA, Edwards ME, Fedorov GB, Haile J, Orlando L, Vinner L, Korneliussen TS, Beilman DW, Bjørk AA, Cao J, Dockter C, Esdale J, Gusarova G, Kjeldsen KK, Mangerud J, Rasic JT, Skadhauge B, Svendsen JI, Tikhonov A, Wincker P, Xing Y, Zhang Y, Froese DG, Rahbek C, Nogues DB, Holden PB, Edwards NR, Durbin R, Meltzer DJ, Kjær KH, Möller P, Willerslev E.
PMID: 34671161
Nature. 2021 Dec;600(7887):86-92. doi: 10.1038/s41586-021-04016-x. Epub 2021 Oct 20.

During the last glacial-interglacial cycle, Arctic biotas experienced substantial climatic changes, yet the nature, extent and rate of their responses are not fully understood

A comparison of three strategies to reduce the burden of osteoarthritis: A population-based microsimulation study.

PloS one

Kopec JA, Sayre EC, Okhmatovskaia A, Cibere J, Li LC, Bansback N, Wong H, Ghanbarian S, Esdaile JM.
PMID: 34879102
PLoS One. 2021 Dec 08;16(12):e0261017. doi: 10.1371/journal.pone.0261017. eCollection 2021.

OBJECTIVES: The purpose of this study was to compare three strategies for reducing population health burden of osteoarthritis (OA): improved pharmacological treatment of OA-related pain, improved access to joint replacement surgery, and prevention of OA by reducing obesity and...

Follicular T-Helper Cells in Marginal Zone Lymphoma: Evidence of an Organoid Immune Response.

The American Journal of dermatopathology

Robson A, Bakr F, Rashidghamat E, Willsmore ZN, Ally M, Greenblatt D, Barlow R, Wain EM, Child F, Esdaile B, Kempf W.
PMID: 34231493
Am J Dermatopathol. 2021 Dec 01;43(12):e197-e203. doi: 10.1097/DAD.0000000000002017.

INTRODUCTION: Primary cutaneous marginal zone B-cell lymphoma (MZL) follows an indolent clinical course. Histopathologically, there is a polymorphous infiltrate that includes small lymphocyte-like and centrocyte-like B cells and plasma cells usually with a substantial T-cell fraction. Primary cutaneous CD4+...

First-line antiretroviral treatment failure and associated factors in HIV patients at the University of Gondar Teaching Hospital, Gondar, Northwest Ethiopia.

HIV/AIDS (Auckland, N.Z.)

Ayalew MB, Kumilachew D, Belay A, Getu S, Teju D, Endale D, Tsegaye Y, Wale Z.
PMID: 27621669
HIV AIDS (Auckl). 2016 Sep 02;8:141-6. doi: 10.2147/HIV.S112048. eCollection 2016.

BACKGROUND: Antiretroviral therapy (ART) restores immune function and reduces HIV-related adverse outcomes. But treatment failure erodes this advantage and leads to an increased morbidity and compromised quality of life in HIV patients. The aim of this study was to...

Capitalizing on the teachable moment: osteoarthritis physical activity and exercise net for improving physical activity in early knee osteoarthritis.

JMIR research protocols

Li LC, Lineker S, Cibere J, Crooks VA, Jones CA, Kopec JA, Lear SA, Pencharz J, Rhodes RE, Esdaile JM.
PMID: 23659903
JMIR Res Protoc. 2013 May 09;2(1):e17. doi: 10.2196/resprot.2553.

BACKGROUND: Practice guidelines emphasize the use of exercise and weight reduction as the first line of management for knee osteoarthritis (OA). However, less than half of the people with mild OA participate in moderate intensity physical activity. Given that...

An evaluation of the proposed OECD testing strategy for skin corrosion.

Alternatives to laboratory animals : ATLA

Worth AP, Fentem JH, Balls M, Botham PA, Curren RD, Earl LK, Esdaile DJ.
PMID: 26042494
Altern Lab Anim. 1998 Sep-Oct;26(5):709-20.

The use of testing strategies which incorporate a range of alternative methods and which use animals only as a last resort is widely considered to provide a reliable way of predicting chemical toxicity while minimising animal testing. The widespread...

Hopping versus Tunneling Mechanism for Long-Range Electron Transfer in Porphyrin Oligomer Bridged Donor-Acceptor Systems.

The journal of physical chemistry. B

Gilbert Gatty M, Kahnt A, Esdaile LJ, Hutin M, Anderson HL, Albinsson B.
PMID: 25751411
J Phys Chem B. 2015 Jun 18;119(24):7598-611. doi: 10.1021/jp5115064. Epub 2015 Mar 18.

Achieving long-range charge transport in molecular systems is interesting to foresee applications of molecules in practical devices. However, designing molecular systems with pre-defined wire-like properties remains difficult due to the lack of understanding of the mechanism for charge transfer....

Late Quaternary dynamics of Arctic biota from ancient environmental genomics.

Nature

Wang Y, Pedersen MW, Alsos IG, De Sanctis B, Racimo F, Prohaska A, Coissac E, Owens HL, Merkel MKF, Fernandez-Guerra A, Rouillard A, Lammers Y, Alberti A, Denoeud F, Money D, Ruter AH, McColl H, Larsen NK, Cherezova AA, Edwards ME, Fedorov GB, Haile J, Orlando L, Vinner L, Korneliussen TS, Beilman DW, Bjørk AA, Cao J, Dockter C, Esdale J, Gusarova G, Kjeldsen KK, Mangerud J, Rasic JT, Skadhauge B, Svendsen JI, Tikhonov A, Wincker P, Xing Y, Zhang Y, Froese DG, Rahbek C, Nogues DB, Holden PB, Edwards NR, Durbin R, Meltzer DJ, Kjær KH, Möller P, Willerslev E.
PMID: 34671161
Nature. 2021 Dec;600(7887):86-92. doi: 10.1038/s41586-021-04016-x. Epub 2021 Oct 20.

During the last glacial-interglacial cycle, Arctic biotas experienced substantial climatic changes, yet the nature, extent and rate of their responses are not fully understood

Azoporphyrin: the porphyrin analogue of azobenzene.

Angewandte Chemie (International ed. in English)

Esdaile LJ, Jensen P, McMurtrie JC, Arnold DP.
PMID: 17278161
Angew Chem Int Ed Engl. 2007;46(12):2090-3. doi: 10.1002/anie.200604658.

No abstract available.

Bias-Driven Conductance Increase with Length in Porphyrin Tapes.

Journal of the American Chemical Society

Leary E, Limburg B, Alanazy A, Sangtarash S, Grace I, Swada K, Esdaile LJ, Noori M, González MT, Rubio-Bollinger G, Sadeghi H, Hodgson A, Agraı T N, Higgins SJ, Lambert CJ, Anderson HL, Nichols RJ.
PMID: 30207150
J Am Chem Soc. 2018 Oct 10;140(40):12877-12883. doi: 10.1021/jacs.8b06338. Epub 2018 Sep 28.

A key goal in molecular electronics has been to find molecules that facilitate efficient charge transport over long distances. Normally, molecular wires become less conductive with increasing length. Here, we report a series of fused porphyrin oligomers for which...

Conformation and packing of porphyrin polymer chains deposited using electrospray on a gold surface.

Angewandte Chemie (International ed. in English)

Saywell A, Sprafke JK, Esdaile LJ, Britton AJ, Rienzo A, Anderson HL, O'Shea JN, Beton PH.
PMID: 20973016
Angew Chem Int Ed Engl. 2010 Nov 22;49(48):9136-9. doi: 10.1002/anie.201004896.

No abstract available.

Showing 13 to 24 of 56 entries