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Showing 13 to 24 of 132 entries
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A Systematic Review of Surgical interventions for the Treatment of Bladder Pain Syndrome/Interstitial Cystitis.

European urology focus

Osman NI, Bratt DG, Downey AP, Esperto F, Inman RD, Chapple CR.
PMID: 32127327
Eur Urol Focus. 2021 Jul;7(4):877-885. doi: 10.1016/j.euf.2020.02.014. Epub 2020 Mar 01.

CONTEXT: Bladder pain syndrome/interstitial cystitis (BPS/IC) is a poorly understood chronic debilitating condition. Surgery is reserved for severe refractory cases; however, there is no consensus on patient selection or optimal approach.OBJECTIVE: To evaluate the evidence relating to the safety...

Metastatic Small-Cell Lung Cancer Presenting as Primary Adrenal Insufficiency.

Case reports in oncological medicine

Esperti S, Stoelting A, Scibelli N, Moccia D, Patel D, Haughton M, Mangano A.
PMID: 32257478
Case Rep Oncol Med. 2020 Mar 11;2020:7018619. doi: 10.1155/2020/7018619. eCollection 2020.

A 40-year-old male smoker with HIV was admitted for cough, hypotension, and abdominal pain for 5 days. Chest radiography showed a right lower lobe consolidation. CT of the chest, abdomen, and pelvis revealed paratracheal adenopathy, a 5.8 × 4.5...

The NLRP3 p.A441V Mutation in .

ACR open rheumatology

Awad F, Assrawi E, Jumeau C, Odent S, Despert V, Cam G, Perdriger A, Louvrier C, Cobret L, Copin B, Chantot-Bastaraud S, Duquesnoy P, Piterboth W, Le Jeunne C, Quenum-Miraillet G, Siffroi JP, Georgin-Lavialle S, Grateau G, Legendre M, Giurgea I, Karabina SA, Amselem S.
PMID: 31777803
ACR Open Rheumatol. 2019 Jun 06;1(4):267-276. doi: 10.1002/acr2.1039. eCollection 2019 Jun.

OBJECTIVE: To determine the molecular and cellular bases of autoinflammatory syndromes in a multigenerational French family with Muckle-Wells syndrome and in a patient originating from Portugal with familial cold autoinflammatory syndrome.METHODS: Sequencing of RESULTS: The same heterozygous mutation (c.1322C>T,...

L'autophagie sélective au cours des infections virales.

Virologie (Montrouge, France)

Daussy CF, Espert L.
PMID: 32260032
Virologie (Montrouge). 2016 Aug 01;20(4):196-206. doi: 10.1684/vir.2016.0665.

Autophagy is a major catabolic pathway involved in several important cellular functions including homeostasis, development, differentiation and immunity. Consequently, deregulations of this process have been observed in several pathologies. Autophagy leads to the lysosomal degradation of cellular components after...

SOCS2 expression in hematopoietic and non-hematopoietic cells during Trypanosoma cruzi infection: Correlation with immune response and cardiac dysfunction.

Clinical immunology (Orlando, Fla.)

Gaio P, Gualdrón-López M, Cramer A, Esper L, de Menezes Filho JER, Cruz JS, Teixeira MM, Machado FS.
PMID: 34954347
Clin Immunol. 2021 Dec 23;234:108913. doi: 10.1016/j.clim.2021.108913. Epub 2021 Dec 23.

Chagas disease has a complex pathogenesis wherein the host immune response is essential for controlling its development. Suppressor of cytokine signaling(SOCS)2 is a crucial protein that regulates cytokine production. In this study, SOCS2 deficiency resulted in an initial imbalance...

Monitoring single-cell dynamics of entry into quiescence during an unperturbed life cycle.

eLife

Jacquel B, Aspert T, Laporte D, Sagot I, Charvin G.
PMID: 34723791
Elife. 2021 Nov 01;10. doi: 10.7554/eLife.73186.

The life cycle of microorganisms is associated with dynamic metabolic transitions and complex cellular responses. In yeast, how metabolic signals control the progressive choreography of structural reorganizations observed in quiescent cells during a natural life cycle remains unclear. We...

Reductions in motoneuron excitability during sustained isometric contractions are dependent on stimulus and contraction intensity.

Journal of neurophysiology

Brownstein CG, Espeit L, Royer N, Ansdell P, Škarabot J, Souron R, Lapole T, Millet GY.
PMID: 33788627
J Neurophysiol. 2021 May 01;125(5):1636-1646. doi: 10.1152/jn.00070.2021. Epub 2021 Mar 31.

Cervicomedullary stimulation provides a means of assessing motoneuron excitability. Previous studies demonstrated that during low-intensity sustained contractions, small cervicomedullary evoked potentials (CMEPs) conditioned using transcranial magnetic stimulation (TMS-CMEPs) are reduced, whereas large TMS-CMEPs are less affected. As small TMS-CMEPs...

Acute Plasma Cell Leukemia Presenting as Primary Hyperammonemic Encephalopathy.

Journal of medical cases

Patel D, Mangano A, Moccia D, Esperti S, Udani K, Henderson J, Balanchivadze N.
PMID: 34434338
J Med Cases. 2020 Oct;11(10):320-323. doi: 10.14740/jmc3559. Epub 2020 Aug 28.

Primary plasma cell leukemia (PPCL) is a rare form of multiple myeloma (MM) and is a rare aggressive disease with a median overall survival of 6 - 11 months. We present a case of acute hyperammonemic encephalopathy as the...

Is urologist burnout different on the other side of the pond? A European perspective.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Pang KH, Webb TE, Esperto F, Osman NI.
PMID: 34406927
Can Urol Assoc J. 2021 Jun;15(6):S25-S30. doi: 10.5489/cuaj.7227.

The rate of burnout among physicians appears to be on the rise and urologist are no exception. In fact, urology appears to be one of the specialties most affected, with European urologists reporting burnout rates of up to 54%...

Development of Structured Sunflower Oil Systems for Decreasing Trans and Saturated Fatty Acid Content in Bakery Creams.

Foods (Basel, Switzerland)

Espert M, Sanz T, Salvador A.
PMID: 33652856
Foods. 2021 Feb 26;10(3). doi: 10.3390/foods10030505.

In this work, the design of low moisture (10%) oil/water emulsions based on sunflower oil were investigated, as well as their application in a bakery cream as a conventional fat replacer. The emulsions were dehydrated to reach 10% moisture...

Data Mining of Free-Text Responses: An Innovative Approach to Analyzing Patient Perspectives on Treatment for Chronic Rhinosinusitis with Nasal Polyps in a Phase IIa Proof-of-Concept Study for Dupilumab.

Patient preference and adherence

Khan AH, Abbe A, Falissard B, Carita P, Bachert C, Mullol J, Reaney M, Chao J, Mannent LP, Amin N, Mahajan P, Pirozzi G, Eckert L.
PMID: 34848949
Patient Prefer Adherence. 2021 Nov 19;15:2577-2586. doi: 10.2147/PPA.S320242. eCollection 2021.

PURPOSE: Patient perspective is an important and increasingly sought-after complement to clinical assessment. The aim of this study was to transcribe individual patients' experience of treatment in a dupilumab clinical trial through free-text responses with analysis using natural language...

Central fatigue aetiology in prolonged trail running races.

Experimental physiology

Espeit L, Brownstein CG, Royer N, Besson T, Martin V, Millet GY, Lapole T.
PMID: 33428289
Exp Physiol. 2021 Mar;106(3):663-672. doi: 10.1113/EP089177. Epub 2021 Jan 18.

NEW FINDINGS: What is the central question of this study? Are spinal and/or supraspinal perturbations implicated in central fatigue induced in the plantar flexor muscles following prolonged trail running races? What is the main finding and its importance? The...

Showing 13 to 24 of 132 entries