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Showing 385 to 389 of 389 entries
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Radiation Therapy without Anesthesia for a 2-Year Old Child using Audio-Visual Assisted Therapeutic Ambience in Radiotherapy (AVATAR).

Practical radiation oncology

Prasad RN, Baliga S, Banner J, Cadieux C, Centnar A, Degnan M, Depinet M, Ewing A, Hobbs N, Jiang AL, Manring I, Perlow HK, Rock A, Skinner LB, Tenney L, Walls V, Hiniker SM, Palmer JD.
PMID: 34971793
Pract Radiat Oncol. 2021 Dec 28; doi: 10.1016/j.prro.2021.12.009. Epub 2021 Dec 28.

Radiation therapy (RT) is essential to managing many pediatric malignancies, but can be anxiety, fear, and discomfort provoking for children due to prolonged treatment time, extended course, and restrictive immobilization. Patients under 10 years frequently require daily general anesthesia...

Positive margins after mastectomy in patients with invasive lobular carcinoma of the breast: Incidence and management strategies.

American journal of surgery

Hewitt KC, Miller P, Piper M, Prionas N, Son JD, Alvarado M, Esserman LJ, Wong JM, Ewing C, Mukhtar RA.
PMID: 34148670
Am J Surg. 2021 Jun 10; doi: 10.1016/j.amjsurg.2021.05.021. Epub 2021 Jun 10.

BACKGROUND: Surgical treatment of invasive lobular carcinoma (ILC) is challenging due to its diffuse growth pattern, and the positive margin rate after mastectomy is poorly described.METHODS: We retrospectively determined the positive margin rate in those with stage I-III ILC...

STATegra: Multi-Omics Data Integration - A Conceptual Scheme With a Bioinformatics Pipeline.

Frontiers in genetics

Planell N, Lagani V, Sebastian-Leon P, van der Kloet F, Ewing E, Karathanasis N, Urdangarin A, Arozarena I, Jagodic M, Tsamardinos I, Tarazona S, Conesa A, Tegner J, Gomez-Cabrero D.
PMID: 33747045
Front Genet. 2021 Mar 04;12:620453. doi: 10.3389/fgene.2021.620453. eCollection 2021.

Technologies for profiling samples using different omics platforms have been at the forefront since the human genome project. Large-scale multi-omics data hold the promise of deciphering different regulatory layers. Yet, while there is a myriad of bioinformatics tools, each...

Vesicular release dynamics are altered by the interaction between the chemical cargo and vesicle membrane lipids.

Chemical science

Asadpour F, Zhang XW, Mazloum-Ardakani M, Mirzaei M, Majdi S, Ewing AG.
PMID: 34447531
Chem Sci. 2021 Jun 25;12(30):10273-10278. doi: 10.1039/d1sc02247d. eCollection 2021 Aug 04.

The release of the cargo from soft vesicles, an essential process for chemical delivery, is mediated by multiple factors. Among them, the regulation by the interaction between the chemical cargo species and the vesicular membrane, widely existing in all...

Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome.

Genome biology

Troskie RL, Jafrani Y, Mercer TR, Ewing AD, Faulkner GJ, Cheetham SW.
PMID: 33971925
Genome Biol. 2021 May 10;22(1):146. doi: 10.1186/s13059-021-02369-0.

Pseudogenes are gene copies presumed to mainly be functionless relics of evolution due to acquired deleterious mutations or transcriptional silencing. Using deep full-length PacBio cDNA sequencing of normal human tissues and cancer cell lines, we identify here hundreds of...

Showing 385 to 389 of 389 entries