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Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome.

Genome biology

Troskie RL, Jafrani Y, Mercer TR, Ewing AD, Faulkner GJ, Cheetham SW.
PMID: 33971925
Genome Biol. 2021 May 10;22(1):146. doi: 10.1186/s13059-021-02369-0.

Pseudogenes are gene copies presumed to mainly be functionless relics of evolution due to acquired deleterious mutations or transcriptional silencing. Using deep full-length PacBio cDNA sequencing of normal human tissues and cancer cell lines, we identify here hundreds of...

Showing 157 to 157 of 157 entries