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Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Buckles VD, Xiong C, Bateman RJ, Hassenstab J, Allegri R, Berman SB, Chhatwal JP, Danek A, Fagan AM, Ghetti B, Goate A, Graff-Radford N, Jucker M, Levin J, Marcus DS, Masters CL, McCue L, McDade E, Mori H, Moulder KL, Noble JM, Paumier K, Preische O, Ringman JM, Fox NC, Salloway S, Schofield PR, Martins R, Vöglein J, Morris JC.
PMID: 34854530
Alzheimers Dement. 2021 Dec 02; doi: 10.1002/alz.12505. Epub 2021 Dec 02.

As prevention trials advance with autosomal dominant Alzheimer disease (ADAD) participants, understanding the similarities and differences between ADAD and "sporadic" late-onset AD (LOAD) is critical to determine generalizability of findings between these cohorts. Cognitive trajectories of ADAD mutation carriers...

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Buckles VD, Xiong C, Bateman RJ, et al. Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease. Alzheimers Dement. 2021;doi: 10.1002/alz.12505.
Buckles, V. D., Xiong, C., Bateman, R. J., Hassenstab, J., Allegri, R., Berman, S. B., Chhatwal, J. P., Danek, A., Fagan, A. M., Ghetti, B., Goate, A., Graff-Radford, N., Jucker, M., Levin, J., Marcus, D. S., Masters, C. L., McCue, L., McDade, E., Mori, H., Moulder, K. L., Noble, J. M., Paumier, K., Preische, O., Ringman, J. M., Fox, N. C., Salloway, S., Schofield, P. R., Martins, R., Vöglein, J., Morris, J. C. (2021). Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease. Alzheimer's & dementia : the journal of the Alzheimer's Association, . https://doi.org/10.1002/alz.12505
Buckles, Virginia D, et al. "Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. (2021). doi: https://doi.org/10.1002/alz.12505
Buckles VD, Xiong C, Bateman RJ, Hassenstab J, Allegri R, Berman SB, Chhatwal JP, Danek A, Fagan AM, Ghetti B, Goate A, Graff-Radford N, Jucker M, Levin J, Marcus DS, Masters CL, McCue L, McDade E, Mori H, Moulder KL, Noble JM, Paumier K, Preische O, Ringman JM, Fox NC, Salloway S, Schofield PR, Martins R, Vöglein J, Morris JC. Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease. Alzheimers Dement. 2021 Dec 02; doi: 10.1002/alz.12505. Epub 2021 Dec 02. PMID: 34854530.
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Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

Browne JE, Cannon LM, Fagan AJ, Cournane S.
PMID: 34998134
Phys Med. 2022 Jan 05;94:65-74. doi: 10.1016/j.ejmp.2021.12.019. Epub 2022 Jan 05.

PURPOSE: Contrast-detail (C-D) and anechoic-target (A-T) detectability are measures of an ultrasound scanner's ability to image lesions of varying contrast and size from background tissue and, as such, they are important tools for grading the imaging capabilities of ultrasound...

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Browne JE, Cannon LM, Fagan AJ, et al. Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners. Phys Med. 2022;94:65-74doi: 10.1016/j.ejmp.2021.12.019.
Browne, J. E., Cannon, L. M., Fagan, A. J., & Cournane, S. (2022). Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners. Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), 9465-74. https://doi.org/10.1016/j.ejmp.2021.12.019
Browne, J E, et al. "Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners." Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) vol. 94 (2022): 65-74. doi: https://doi.org/10.1016/j.ejmp.2021.12.019
Browne JE, Cannon LM, Fagan AJ, Cournane S. Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners. Phys Med. 2022 Jan 05;94:65-74. doi: 10.1016/j.ejmp.2021.12.019. Epub 2022 Jan 05. PMID: 34998134.
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Evaluation of the Recovery Engagement and Coordination for Health-Veterans Enhanced Treatment Suicide Risk Modeling Clinical Program in the Veterans Health Administration.

JAMA network open

McCarthy JF, Cooper SA, Dent KR, Eagan AE, Matarazzo BB, Hannemann CM, Reger MA, Landes SJ, Trafton JA, Schoenbaum M, Katz IR.
PMID: 34661661
JAMA Netw Open. 2021 Oct 01;4(10):e2129900. doi: 10.1001/jamanetworkopen.2021.29900.

IMPORTANCE: The Veterans Health Administration (VHA) implemented a national clinical program using a suicide risk prediction algorithm, Recovery Engagement and Coordination for Health-Veterans Enhanced Treatment (REACH VET), in which clinicians facilitate care enhancements for individuals identified in local top...

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McCarthy JF, Cooper SA, Dent KR, et al. Evaluation of the Recovery Engagement and Coordination for Health-Veterans Enhanced Treatment Suicide Risk Modeling Clinical Program in the Veterans Health Administration. JAMA Netw Open. 2021;4(10):e2129900doi: 10.1001/jamanetworkopen.2021.29900.
McCarthy, J. F., Cooper, S. A., Dent, K. R., Eagan, A. E., Matarazzo, B. B., Hannemann, C. M., Reger, M. A., Landes, S. J., Trafton, J. A., Schoenbaum, M., & Katz, I. R. (2021). Evaluation of the Recovery Engagement and Coordination for Health-Veterans Enhanced Treatment Suicide Risk Modeling Clinical Program in the Veterans Health Administration. JAMA network open, 4(10), e2129900. https://doi.org/10.1001/jamanetworkopen.2021.29900
McCarthy, John F, et al. "Evaluation of the Recovery Engagement and Coordination for Health-Veterans Enhanced Treatment Suicide Risk Modeling Clinical Program in the Veterans Health Administration." JAMA network open vol. 4,10 (2021): e2129900. doi: https://doi.org/10.1001/jamanetworkopen.2021.29900
McCarthy JF, Cooper SA, Dent KR, Eagan AE, Matarazzo BB, Hannemann CM, Reger MA, Landes SJ, Trafton JA, Schoenbaum M, Katz IR. Evaluation of the Recovery Engagement and Coordination for Health-Veterans Enhanced Treatment Suicide Risk Modeling Clinical Program in the Veterans Health Administration. JAMA Netw Open. 2021 Oct 01;4(10):e2129900. doi: 10.1001/jamanetworkopen.2021.29900. PMID: 34661661; PMCID: PMC8524305.
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Limited Longitudinal Change in Self-reported Spatial Navigation Ability in Preclinical Alzheimer Disease.

Alzheimer disease and associated disorders

Levine TF, Roe CM, Babulal GM, Fagan AM, Head D.
PMID: 34966024
Alzheimer Dis Assoc Disord. 2021 Dec 30; doi: 10.1097/WAD.0000000000000487. Epub 2021 Dec 30.

Subtle changes in objective spatial navigation ability have been observed in the preclinical stage of Alzheimer disease (AD) cross-sectionally and have been found to predict clinical progression. However, longitudinal change in self-reported spatial navigation ability in preclinical AD has...

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Levine TF, Roe CM, Babulal GM, et al. Limited Longitudinal Change in Self-reported Spatial Navigation Ability in Preclinical Alzheimer Disease. Alzheimer Dis Assoc Disord. 2021;doi: 10.1097/WAD.0000000000000487.
Levine, T. F., Roe, C. M., Babulal, G. M., Fagan, A. M., & Head, D. (2021). Limited Longitudinal Change in Self-reported Spatial Navigation Ability in Preclinical Alzheimer Disease. Alzheimer disease and associated disorders, . https://doi.org/10.1097/WAD.0000000000000487
Levine, Taylor F, et al. "Limited Longitudinal Change in Self-reported Spatial Navigation Ability in Preclinical Alzheimer Disease." Alzheimer disease and associated disorders vol. (2021). doi: https://doi.org/10.1097/WAD.0000000000000487
Levine TF, Roe CM, Babulal GM, Fagan AM, Head D. Limited Longitudinal Change in Self-reported Spatial Navigation Ability in Preclinical Alzheimer Disease. Alzheimer Dis Assoc Disord. 2021 Dec 30; doi: 10.1097/WAD.0000000000000487. Epub 2021 Dec 30. PMID: 34966024.
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Interaction of bacterial metagenome and virome in patients with cirrhosis and hepatic encephalopathy.

Gut

Bajaj JS, Sikaroodi M, Shamsaddini A, Henseler Z, Santiago-Rodriguez T, Acharya C, Fagan A, Hylemon PB, Fuchs M, Gavis E, Ward T, Knights D, Gillevet PM.
PMID: 32998876
Gut. 2021 Jun;70(6):1162-1173. doi: 10.1136/gutjnl-2020-322470. Epub 2020 Sep 30.

OBJECTIVE: Altered bacterial composition is associated with disease progression in cirrhosis but the role of virome, especially phages, is unclear.DESIGN: Cross-sectional and pre/post rifaximin cohorts were enrolled. Cross-sectional: controls and cirrhotic outpatients (compensated, on lactulose (Cirr-L), on rifaximin (Cirr-LR))...

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Bajaj JS, Sikaroodi M, Shamsaddini A, et al. Interaction of bacterial metagenome and virome in patients with cirrhosis and hepatic encephalopathy. Gut. 2020;70(6):1162-1173doi: 10.1136/gutjnl-2020-322470.
Bajaj, J. S., Sikaroodi, M., Shamsaddini, A., Henseler, Z., Santiago-Rodriguez, T., Acharya, C., Fagan, A., Hylemon, P. B., Fuchs, M., Gavis, E., Ward, T., Knights, D., & Gillevet, P. M. (2021). Interaction of bacterial metagenome and virome in patients with cirrhosis and hepatic encephalopathy. Gut, 70(6), 1162-1173. https://doi.org/10.1136/gutjnl-2020-322470
Bajaj, Jasmohan S, et al. "Interaction of bacterial metagenome and virome in patients with cirrhosis and hepatic encephalopathy." Gut vol. 70,6 (2021): 1162-1173. doi: https://doi.org/10.1136/gutjnl-2020-322470
Bajaj JS, Sikaroodi M, Shamsaddini A, Henseler Z, Santiago-Rodriguez T, Acharya C, Fagan A, Hylemon PB, Fuchs M, Gavis E, Ward T, Knights D, Gillevet PM. Interaction of bacterial metagenome and virome in patients with cirrhosis and hepatic encephalopathy. Gut. 2021 Jun;70(6):1162-1173. doi: 10.1136/gutjnl-2020-322470. Epub 2020 Sep 30. PMID: 32998876.
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African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants.

Neurology. Genetics

Schindler SE, Cruchaga C, Joseph A, McCue L, Farias FHG, Wilkins CH, Deming Y, Henson RL, Mikesell RJ, Piccio L, Llibre-Guerra JJ, Moulder KL, Fagan AM, Ances BM, Benzinger TLS, Xiong C, Holtzman DM, Morris JC.
PMID: 33884297
Neurol Genet. 2021 Mar 04;7(2):e571. doi: 10.1212/NXG.0000000000000571. eCollection 2021 Apr.

OBJECTIVE: To evaluate for racial differences in triggering receptor expressed on myeloid cells 2 (TREM2), a key immune mediator in Alzheimer disease, the levels of CSF soluble TREM2 (sTREM2), and the frequency of associated genetic variants were compared in...

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Schindler SE, Cruchaga C, Joseph A, et al. African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants. Neurol Genet. 2021;7(2):e571doi: 10.1212/NXG.0000000000000571.
Schindler, S. E., Cruchaga, C., Joseph, A., McCue, L., Farias, F. H. G., Wilkins, C. H., Deming, Y., Henson, R. L., Mikesell, R. J., Piccio, L., Llibre-Guerra, J. J., Moulder, K. L., Fagan, A. M., Ances, B. M., Benzinger, T. L. S., Xiong, C., Holtzman, D. M., & Morris, J. C. (2021). African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants. Neurology. Genetics, 7(2), e571. https://doi.org/10.1212/NXG.0000000000000571
Schindler, Suzanne E, et al. "African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants." Neurology. Genetics vol. 7,2 (2021): e571. doi: https://doi.org/10.1212/NXG.0000000000000571
Schindler SE, Cruchaga C, Joseph A, McCue L, Farias FHG, Wilkins CH, Deming Y, Henson RL, Mikesell RJ, Piccio L, Llibre-Guerra JJ, Moulder KL, Fagan AM, Ances BM, Benzinger TLS, Xiong C, Holtzman DM, Morris JC. African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants. Neurol Genet. 2021 Mar 04;7(2):e571. doi: 10.1212/NXG.0000000000000571. eCollection 2021 Apr. PMID: 33884297; PMCID: PMC8054965.
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Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing.

Journal of clinical and experimental neuropsychology

Wilks H, Aschenbrenner AJ, Gordon BA, Balota DA, Fagan AM, Musiek E, Balls-Berry J, Benzinger TLS, Cruchaga C, Morris JC, Hassenstab J.
PMID: 35037593
J Clin Exp Neuropsychol. 2022 Jan 16;1-13. doi: 10.1080/13803395.2021.2009447. Epub 2022 Jan 16.

Decades of research has established a shift from an "eveningness" preference to a "morningness" preference with increasing age. Accordingly, older adults typically have better cognition in morning hours compared to evening hours. We present the first known attempt to...

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Wilks H, Aschenbrenner AJ, Gordon BA, et al. Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing. J Clin Exp Neuropsychol. 2022;1-13doi: 10.1080/13803395.2021.2009447.
Wilks, H., Aschenbrenner, A. J., Gordon, B. A., Balota, D. A., Fagan, A. M., Musiek, E., Balls-Berry, J., Benzinger, T. L. S., Cruchaga, C., Morris, J. C., & Hassenstab, J. (2022). Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing. Journal of clinical and experimental neuropsychology, 1-13. https://doi.org/10.1080/13803395.2021.2009447
Wilks, Hannah, et al. "Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing." Journal of clinical and experimental neuropsychology vol. (2022): 1-13. doi: https://doi.org/10.1080/13803395.2021.2009447
Wilks H, Aschenbrenner AJ, Gordon BA, Balota DA, Fagan AM, Musiek E, Balls-Berry J, Benzinger TLS, Cruchaga C, Morris JC, Hassenstab J. Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing. J Clin Exp Neuropsychol. 2022 Jan 16;1-13. doi: 10.1080/13803395.2021.2009447. Epub 2022 Jan 16. PMID: 35037593.
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Late papillary muscle rupture and tricuspid regurgitation related to transvenous endocardial lead extraction.

HeartRhythm case reports

Beccarino NJ, Pagan EA, Henry S, Yu PJ, John RM.
PMID: 34552845
HeartRhythm Case Rep. 2021 May 26;7(9):577-580. doi: 10.1016/j.hrcr.2021.05.013. eCollection 2021 Sep.

No abstract available.

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Beccarino NJ, Pagan EA, Henry S, et al. Late papillary muscle rupture and tricuspid regurgitation related to transvenous endocardial lead extraction. HeartRhythm Case Rep. 2021;7(9):577-580doi: 10.1016/j.hrcr.2021.05.013.
Beccarino, N. J., Pagan, E. A., Henry, S., Yu, P. J., & John, R. M. (2021). Late papillary muscle rupture and tricuspid regurgitation related to transvenous endocardial lead extraction. HeartRhythm case reports, 7(9), 577-580. https://doi.org/10.1016/j.hrcr.2021.05.013
Beccarino, Nicholas J, et al. "Late papillary muscle rupture and tricuspid regurgitation related to transvenous endocardial lead extraction." HeartRhythm case reports vol. 7,9 (2021): 577-580. doi: https://doi.org/10.1016/j.hrcr.2021.05.013
Beccarino NJ, Pagan EA, Henry S, Yu PJ, John RM. Late papillary muscle rupture and tricuspid regurgitation related to transvenous endocardial lead extraction. HeartRhythm Case Rep. 2021 May 26;7(9):577-580. doi: 10.1016/j.hrcr.2021.05.013. eCollection 2021 Sep. PMID: 34552845; PMCID: PMC8441198.
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Biventricular diastolic dysfunction, thrombocytopenia, and red blood cell macrocytosis in experimental pulmonary arterial hypertension.

Pulmonary circulation

Lee JY, Fagan KA, Zhou C, Batten L, Cohen MV, Stevens T.
PMID: 32518619
Pulm Circ. 2020 May 26;10(2):2045894020908787. doi: 10.1177/2045894020908787. eCollection 2020.

Pulmonary arterial hypertension is a fatal disease, where death is associated with right heart failure and reduced cardiorespiratory reserve. The Sugen 5416, hypoxia and normoxia Fischer rat model mimics human pulmonary arterial hypertension, although the cause(s) of death remains...

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Lee JY, Fagan KA, Zhou C, et al. Biventricular diastolic dysfunction, thrombocytopenia, and red blood cell macrocytosis in experimental pulmonary arterial hypertension. Pulm Circ. 2020;10(2):2045894020908787doi: 10.1177/2045894020908787.
Lee, J. Y., Fagan, K. A., Zhou, C., Batten, L., Cohen, M. V., & Stevens, T. (2020). Biventricular diastolic dysfunction, thrombocytopenia, and red blood cell macrocytosis in experimental pulmonary arterial hypertension. Pulmonary circulation, 10(2), 2045894020908787. https://doi.org/10.1177/2045894020908787
Lee, Ji Young, et al. "Biventricular diastolic dysfunction, thrombocytopenia, and red blood cell macrocytosis in experimental pulmonary arterial hypertension." Pulmonary circulation vol. 10,2 (2020): 2045894020908787. doi: https://doi.org/10.1177/2045894020908787
Lee JY, Fagan KA, Zhou C, Batten L, Cohen MV, Stevens T. Biventricular diastolic dysfunction, thrombocytopenia, and red blood cell macrocytosis in experimental pulmonary arterial hypertension. Pulm Circ. 2020 May 26;10(2):2045894020908787. doi: 10.1177/2045894020908787. eCollection 2020. PMID: 32518619; PMCID: PMC7252389.
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Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25.

Neurobiology of aging

Butt OH, Long JM, Henson RL, Herries E, Sutphen CL, Fagan AM, Cruchaga C, Ladenson JH, Holtzman DM, Morris JC, Ances BM, Schindler SE.
PMID: 33765432
Neurobiol Aging. 2021 Jun;102:64-72. doi: 10.1016/j.neurobiolaging.2021.02.008. Epub 2021 Feb 11.

Cerebrospinal fluid (CSF) synaptosomal-associated protein 25 (SNAP-25) and neurogranin (Ng) are recently described biomarkers for pre- and postsynaptic integrity known to be elevated in symptomatic Alzheimer disease (AD). Their relationship with Apolipoprotein E (APOE) ε4 carrier status, the major...

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Butt OH, Long JM, Henson RL, et al. Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25. Neurobiol Aging. 2021;102:64-72doi: 10.1016/j.neurobiolaging.2021.02.008.
Butt, O. H., Long, J. M., Henson, R. L., Herries, E., Sutphen, C. L., Fagan, A. M., Cruchaga, C., Ladenson, J. H., Holtzman, D. M., Morris, J. C., Ances, B. M., Schindler, S. E. (2021). Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25. Neurobiology of aging, 10264-72. https://doi.org/10.1016/j.neurobiolaging.2021.02.008
Butt, Omar H, et al. "Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25." Neurobiology of aging vol. 102 (2021): 64-72. doi: https://doi.org/10.1016/j.neurobiolaging.2021.02.008
Butt OH, Long JM, Henson RL, Herries E, Sutphen CL, Fagan AM, Cruchaga C, Ladenson JH, Holtzman DM, Morris JC, Ances BM, Schindler SE. Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25. Neurobiol Aging. 2021 Jun;102:64-72. doi: 10.1016/j.neurobiolaging.2021.02.008. Epub 2021 Feb 11. PMID: 33765432.
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Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

Browne JE, Cannon LM, Fagan AJ, Cournane S.
PMID: 34998134
Phys Med. 2022 Jan 05;94:65-74. doi: 10.1016/j.ejmp.2021.12.019. Epub 2022 Jan 05.

PURPOSE: Contrast-detail (C-D) and anechoic-target (A-T) detectability are measures of an ultrasound scanner's ability to image lesions of varying contrast and size from background tissue and, as such, they are important tools for grading the imaging capabilities of ultrasound...

Cite
Browne JE, Cannon LM, Fagan AJ, et al. Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners. Phys Med. 2022;94:65-74doi: 10.1016/j.ejmp.2021.12.019.
Browne, J. E., Cannon, L. M., Fagan, A. J., & Cournane, S. (2022). Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners. Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), 9465-74. https://doi.org/10.1016/j.ejmp.2021.12.019
Browne, J E, et al. "Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners." Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) vol. 94 (2022): 65-74. doi: https://doi.org/10.1016/j.ejmp.2021.12.019
Browne JE, Cannon LM, Fagan AJ, Cournane S. Development of a focal lesion phantom with clinically relevant lesion characteristics for image quality evaluation of breast ultrasound scanners. Phys Med. 2022 Jan 05;94:65-74. doi: 10.1016/j.ejmp.2021.12.019. Epub 2022 Jan 05. PMID: 34998134.
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Leadless pacemaker implant, anticoagulation status, and outcomes: Results from the Micra Transcatheter Pacing System Post-Approval Registry.

Heart rhythm

El-Chami MF, Garweg C, Iacopino S, Al-Samadi F, Martinez-Sande JL, Tondo C, Johansen JB, Prat XV, Piccini JP, Cha YM, Grubman E, Bordachar P, Roberts PR, Soejima K, Stromberg K, Fagan DH, Clementy N.
PMID: 34757189
Heart Rhythm. 2021 Oct 29; doi: 10.1016/j.hrthm.2021.10.023. Epub 2021 Oct 29.

BACKGROUND: Early results from the Micra investigational trial and Micra Post-Approval Registry (PAR) demonstrated excellent safety and device performance; however, outcomes based on anticoagulation (AC) status at implant have not been evaluated.OBJECTIVE: The purpose of this study was to...

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El-Chami MF, Garweg C, Iacopino S, et al. Leadless pacemaker implant, anticoagulation status, and outcomes: Results from the Micra Transcatheter Pacing System Post-Approval Registry. Heart Rhythm. 2021;doi: 10.1016/j.hrthm.2021.10.023.
El-Chami, M. F., Garweg, C., Iacopino, S., Al-Samadi, F., Martinez-Sande, J. L., Tondo, C., Johansen, J. B., Prat, X. V., Piccini, J. P., Cha, Y. M., Grubman, E., Bordachar, P., Roberts, P. R., Soejima, K., Stromberg, K., Fagan, D. H., & Clementy, N. (2021). Leadless pacemaker implant, anticoagulation status, and outcomes: Results from the Micra Transcatheter Pacing System Post-Approval Registry. Heart rhythm, . https://doi.org/10.1016/j.hrthm.2021.10.023
El-Chami, Mikhael F, et al. "Leadless pacemaker implant, anticoagulation status, and outcomes: Results from the Micra Transcatheter Pacing System Post-Approval Registry." Heart rhythm vol. (2021). doi: https://doi.org/10.1016/j.hrthm.2021.10.023
El-Chami MF, Garweg C, Iacopino S, Al-Samadi F, Martinez-Sande JL, Tondo C, Johansen JB, Prat XV, Piccini JP, Cha YM, Grubman E, Bordachar P, Roberts PR, Soejima K, Stromberg K, Fagan DH, Clementy N. Leadless pacemaker implant, anticoagulation status, and outcomes: Results from the Micra Transcatheter Pacing System Post-Approval Registry. Heart Rhythm. 2021 Oct 29; doi: 10.1016/j.hrthm.2021.10.023. Epub 2021 Oct 29. PMID: 34757189.
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