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Showing 25 to 36 of 129 entries
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Anti-tumor effects of an ID antagonist with no observed acquired resistance.

NPJ breast cancer

Wojnarowicz PM, Escolano MG, Huang YH, Desai B, Chin Y, Shah R, Xu S, Yadav S, Yaklichkin S, Ouerfelli O, Soni RK, Philip J, Montrose DC, Healey JH, Rajasekhar VK, Garland WA, Ratiu J, Zhuang Y, Norton L, Rosen N, Hendrickson RC, Zhou XK, Iavarone A, Massague J, Dannenberg AJ, Lasorella A, Benezra R.
PMID: 34031428
NPJ Breast Cancer. 2021 May 24;7(1):58. doi: 10.1038/s41523-021-00266-0.

ID proteins are helix-loop-helix (HLH) transcriptional regulators frequently overexpressed in cancer. ID proteins inhibit basic-HLH transcription factors often blocking differentiation and sustaining proliferation. A small-molecule, AGX51, targets ID proteins for degradation and impairs ocular neovascularization in mouse models. Here...

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Wojnarowicz PM, Escolano MG, Huang YH, et al. Anti-tumor effects of an ID antagonist with no observed acquired resistance. NPJ Breast Cancer. 2021;7(1):58doi: 10.1038/s41523-021-00266-0.
Wojnarowicz, P. M., Escolano, M. G., Huang, Y. H., Desai, B., Chin, Y., Shah, R., Xu, S., Yadav, S., Yaklichkin, S., Ouerfelli, O., Soni, R. K., Philip, J., Montrose, D. C., Healey, J. H., Rajasekhar, V. K., Garland, W. A., Ratiu, J., Zhuang, Y., Norton, L., Rosen, N., Hendrickson, R. C., Zhou, X. K., Iavarone, A., Massague, J., Dannenberg, A. J., Lasorella, A., & Benezra, R. (2021). Anti-tumor effects of an ID antagonist with no observed acquired resistance. NPJ breast cancer, 7(1), 58. https://doi.org/10.1038/s41523-021-00266-0
Wojnarowicz, Paulina M, et al. "Anti-tumor effects of an ID antagonist with no observed acquired resistance." NPJ breast cancer vol. 7,1 (2021): 58. doi: https://doi.org/10.1038/s41523-021-00266-0
Wojnarowicz PM, Escolano MG, Huang YH, Desai B, Chin Y, Shah R, Xu S, Yadav S, Yaklichkin S, Ouerfelli O, Soni RK, Philip J, Montrose DC, Healey JH, Rajasekhar VK, Garland WA, Ratiu J, Zhuang Y, Norton L, Rosen N, Hendrickson RC, Zhou XK, Iavarone A, Massague J, Dannenberg AJ, Lasorella A, Benezra R. Anti-tumor effects of an ID antagonist with no observed acquired resistance. NPJ Breast Cancer. 2021 May 24;7(1):58. doi: 10.1038/s41523-021-00266-0. PMID: 34031428; PMCID: PMC8144414.
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Birthweight and subsequent risk for thyroid and autoimmune conditions in postmenopausal women.

Journal of developmental origins of health and disease

Monahan B, Farland LV, Shadyab AH, Hankinson SE, Manson JE, Spracklen CN.
PMID: 34658316
J Dev Orig Health Dis. 2021 Oct 18;1-8. doi: 10.1017/S204017442100057X. Epub 2021 Oct 18.

The objective of this study was to determine the association between birthweight and risk of thyroid and autoimmune conditions in a large sample of postmenopausal women. Baseline data from the Women's Health Initiative (n = 80,806) were used to...

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Monahan B, Farland LV, Shadyab AH, et al. Birthweight and subsequent risk for thyroid and autoimmune conditions in postmenopausal women. J Dev Orig Health Dis. 2021;1-8doi: 10.1017/S204017442100057X.
Monahan, B., Farland, L. V., Shadyab, A. H., Hankinson, S. E., Manson, J. E., & Spracklen, C. N. (2021). Birthweight and subsequent risk for thyroid and autoimmune conditions in postmenopausal women. Journal of developmental origins of health and disease, 1-8. https://doi.org/10.1017/S204017442100057X
Monahan, Brian, et al. "Birthweight and subsequent risk for thyroid and autoimmune conditions in postmenopausal women." Journal of developmental origins of health and disease vol. (2021): 1-8. doi: https://doi.org/10.1017/S204017442100057X
Monahan B, Farland LV, Shadyab AH, Hankinson SE, Manson JE, Spracklen CN. Birthweight and subsequent risk for thyroid and autoimmune conditions in postmenopausal women. J Dev Orig Health Dis. 2021 Oct 18;1-8. doi: 10.1017/S204017442100057X. Epub 2021 Oct 18. PMID: 34658316.
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Adverse Pregnancy Outcomes and Incident Heart Failure in the Women's Health Initiative.

JAMA network open

Hansen AL, Søndergaard MM, Hlatky MA, Vittinghof E, Nah G, Stefanick ML, Manson JE, Farland LV, Wells GL, Mongraw-Chaffin M, Gunderson EP, Van Horn L, Wild RA, Liu B, Shadyab AH, Allison MA, Liu S, Eaton CB, Honigberg MC, Parikh NI.
PMID: 34882182
JAMA Netw Open. 2021 Dec 01;4(12):e2138071. doi: 10.1001/jamanetworkopen.2021.38071.

IMPORTANCE: Some prior evidence suggests that adverse pregnancy outcomes (APOs) may be associated with heart failure (HF). Identifying unique factors associated with the risk of HF and studying HF subtypes are important next steps.OBJECTIVE: To investigate the association of...

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Hansen AL, Søndergaard MM, Hlatky MA, et al. Adverse Pregnancy Outcomes and Incident Heart Failure in the Women's Health Initiative. JAMA Netw Open. 2021;4(12):e2138071doi: 10.1001/jamanetworkopen.2021.38071.
Hansen, A. L., Søndergaard, M. M., Hlatky, M. A., Vittinghof, E., Nah, G., Stefanick, M. L., Manson, J. E., Farland, L. V., Wells, G. L., Mongraw-Chaffin, M., Gunderson, E. P., Van Horn, L., Wild, R. A., Liu, B., Shadyab, A. H., Allison, M. A., Liu, S., Eaton, C. B., Honigberg, M. C., & Parikh, N. I. (2021). Adverse Pregnancy Outcomes and Incident Heart Failure in the Women's Health Initiative. JAMA network open, 4(12), e2138071. https://doi.org/10.1001/jamanetworkopen.2021.38071
Hansen, Aleksander L, et al. "Adverse Pregnancy Outcomes and Incident Heart Failure in the Women's Health Initiative." JAMA network open vol. 4,12 (2021): e2138071. doi: https://doi.org/10.1001/jamanetworkopen.2021.38071
Hansen AL, Søndergaard MM, Hlatky MA, Vittinghof E, Nah G, Stefanick ML, Manson JE, Farland LV, Wells GL, Mongraw-Chaffin M, Gunderson EP, Van Horn L, Wild RA, Liu B, Shadyab AH, Allison MA, Liu S, Eaton CB, Honigberg MC, Parikh NI. Adverse Pregnancy Outcomes and Incident Heart Failure in the Women's Health Initiative. JAMA Netw Open. 2021 Dec 01;4(12):e2138071. doi: 10.1001/jamanetworkopen.2021.38071. PMID: 34882182; PMCID: PMC8662370.
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Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A.

Frontiers in cell and developmental biology

Stem C, Rodman C, Ramamurthy RM, George S, Meares D, Farland A, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada G.
PMID: 34447745
Front Cell Dev Biol. 2021 Aug 10;9:678117. doi: 10.3389/fcell.2021.678117. eCollection 2021.

Patients with the severe form of hemophilia A (HA) present with a severe phenotype, and can suffer from life-threatening, spontaneous hemorrhaging. While prophylactic FVIII infusions have revolutionized the clinical management of HA, this treatment is short-lived, expensive, and it...

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Stem C, Rodman C, Ramamurthy RM, et al. Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A. Front Cell Dev Biol. 2021;9:678117doi: 10.3389/fcell.2021.678117.
Stem, C., Rodman, C., Ramamurthy, R. M., George, S., Meares, D., Farland, A., Atala, A., Doering, C. B., Spencer, H. T., Porada, C. D., & Almeida-Porada, G. (2021). Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A. Frontiers in cell and developmental biology, 9678117. https://doi.org/10.3389/fcell.2021.678117
Stem, Christopher, et al. "Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A." Frontiers in cell and developmental biology vol. 9 (2021): 678117. doi: https://doi.org/10.3389/fcell.2021.678117
Stem C, Rodman C, Ramamurthy RM, George S, Meares D, Farland A, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada G. Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A. Front Cell Dev Biol. 2021 Aug 10;9:678117. doi: 10.3389/fcell.2021.678117. eCollection 2021. PMID: 34447745; PMCID: PMC8383113.
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Using evaluation to enhance a pre-exposure prophylaxis (PrEP) social marketing campaign in real time in Los Angeles County, California.

Evaluation and program planning

Nakelsky S, Moore L, Garland WH.
PMID: 34452743
Eval Program Plann. 2022 Feb;90:101988. doi: 10.1016/j.evalprogplan.2021.101988. Epub 2021 Aug 13.

OBJECTIVE: To describe the application of a formative evaluation conducted concurrently with implementation of a public health social marketing campaign to allow for substantive changes to the campaign messaging to subsequently improve acceptability.METHOD: A serial cross-sectional survey was used...

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Nakelsky S, Moore L, Garland WH. Using evaluation to enhance a pre-exposure prophylaxis (PrEP) social marketing campaign in real time in Los Angeles County, California. Eval Program Plann. 2021;90:101988doi: 10.1016/j.evalprogplan.2021.101988.
Nakelsky, S., Moore, L., & Garland, W. H. (2022). Using evaluation to enhance a pre-exposure prophylaxis (PrEP) social marketing campaign in real time in Los Angeles County, California. Evaluation and program planning, 90101988. https://doi.org/10.1016/j.evalprogplan.2021.101988
Nakelsky, Shoshanna, et al. "Using evaluation to enhance a pre-exposure prophylaxis (PrEP) social marketing campaign in real time in Los Angeles County, California." Evaluation and program planning vol. 90 (2022): 101988. doi: https://doi.org/10.1016/j.evalprogplan.2021.101988
Nakelsky S, Moore L, Garland WH. Using evaluation to enhance a pre-exposure prophylaxis (PrEP) social marketing campaign in real time in Los Angeles County, California. Eval Program Plann. 2022 Feb;90:101988. doi: 10.1016/j.evalprogplan.2021.101988. Epub 2021 Aug 13. PMID: 34452743.
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Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women.

Circulation

Honigberg MC, Zekavat SM, Niroula A, Griffin GK, Bick AG, Pirruccello JP, Nakao T, Whitsel EA, Farland LV, Laurie C, Kooperberg C, Manson JE, Gabriel S, Libby P, Reiner AP, Ebert BL, Natarajan P.
PMID: 33161765
Circulation. 2021 Feb 02;143(5):410-423. doi: 10.1161/CIRCULATIONAHA.120.051775. Epub 2020 Nov 09.

BACKGROUND: Premature menopause is an independent risk factor for cardiovascular disease in women, but mechanisms underlying this association remain unclear. Clonal hematopoiesis of indeterminate potential (CHIP), the age-related expansion of hematopoietic cells with leukemogenic mutations without detectable malignancy, is...

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Honigberg MC, Zekavat SM, Niroula A, et al. Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women. Circulation. 2020;143(5):410-423doi: 10.1161/CIRCULATIONAHA.120.051775.
Honigberg, M. C., Zekavat, S. M., Niroula, A., Griffin, G. K., Bick, A. G., Pirruccello, J. P., Nakao, T., Whitsel, E. A., Farland, L. V., Laurie, C., Kooperberg, C., Manson, J. E., Gabriel, S., Libby, P., Reiner, A. P., Ebert, B. L., & Natarajan, P. (2021). Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women. Circulation, 143(5), 410-423. https://doi.org/10.1161/CIRCULATIONAHA.120.051775
Honigberg, Michael C, et al. "Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women." Circulation vol. 143,5 (2021): 410-423. doi: https://doi.org/10.1161/CIRCULATIONAHA.120.051775
Honigberg MC, Zekavat SM, Niroula A, Griffin GK, Bick AG, Pirruccello JP, Nakao T, Whitsel EA, Farland LV, Laurie C, Kooperberg C, Manson JE, Gabriel S, Libby P, Reiner AP, Ebert BL, Natarajan P. Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women. Circulation. 2021 Feb 02;143(5):410-423. doi: 10.1161/CIRCULATIONAHA.120.051775. Epub 2020 Nov 09. PMID: 33161765; PMCID: PMC7911856.
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The epidemiology of gynaecologic health: contemporary opportunities and challenges.

Journal of epidemiology and community health

Hoffman SR, Farland LV, Doll KM, Nicholson WK, Wright MA, Robinson WR.
PMID: 33109525
J Epidemiol Community Health. 2020 Oct 27; doi: 10.1136/jech-2019-213149. Epub 2020 Oct 27.

The field of reproductive epidemiology has primarily focused on reproductive outcomes and gynaecologic cancers. The study of non-cancerous, gynaecologic conditions (eg, uterine fibroids, endometriosis) has not received serious treatment in existing epidemiology textbooks and reproductive epidemiology curricula. Further, these...

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Hoffman SR, Farland LV, Doll KM, et al. The epidemiology of gynaecologic health: contemporary opportunities and challenges. J Epidemiol Community Health. 2020;doi: 10.1136/jech-2019-213149.
Hoffman, S. R., Farland, L. V., Doll, K. M., Nicholson, W. K., Wright, M. A., & Robinson, W. R. (2020). The epidemiology of gynaecologic health: contemporary opportunities and challenges. Journal of epidemiology and community health, . https://doi.org/10.1136/jech-2019-213149
Hoffman, Sarah R, et al. "The epidemiology of gynaecologic health: contemporary opportunities and challenges." Journal of epidemiology and community health vol. (2020). doi: https://doi.org/10.1136/jech-2019-213149
Hoffman SR, Farland LV, Doll KM, Nicholson WK, Wright MA, Robinson WR. The epidemiology of gynaecologic health: contemporary opportunities and challenges. J Epidemiol Community Health. 2020 Oct 27; doi: 10.1136/jech-2019-213149. Epub 2020 Oct 27. PMID: 33109525; PMCID: PMC8095335.
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The importance of mediation in reproductive health studies.

Human reproduction (Oxford, England)

Farland LV, Correia KFB, Dodge LE, Modest AM, Williams PL, Smith LH, Toth TL, Hacker MR, Missmer SA.
PMID: 32424401
Hum Reprod. 2020 Jun 01;35(6):1262-1266. doi: 10.1093/humrep/deaa064.

A mediator is a factor that occurs after the exposure of interest, precedes the outcome of interest (i.e. between the exposure and the outcome) and is associated with both the exposure and the outcome of interest (i.e. is on...

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Farland LV, Correia KFB, Dodge LE, et al. The importance of mediation in reproductive health studies. Hum Reprod. 2020;35(6):1262-1266doi: 10.1093/humrep/deaa064.
Farland, L. V., Correia, K. F. B., Dodge, L. E., Modest, A. M., Williams, P. L., Smith, L. H., Toth, T. L., Hacker, M. R., & Missmer, S. A. (2020). The importance of mediation in reproductive health studies. Human reproduction (Oxford, England), 35(6), 1262-1266. https://doi.org/10.1093/humrep/deaa064
Farland, Leslie V, et al. "The importance of mediation in reproductive health studies." Human reproduction (Oxford, England) vol. 35,6 (2020): 1262-1266. doi: https://doi.org/10.1093/humrep/deaa064
Farland LV, Correia KFB, Dodge LE, Modest AM, Williams PL, Smith LH, Toth TL, Hacker MR, Missmer SA. The importance of mediation in reproductive health studies. Hum Reprod. 2020 Jun 01;35(6):1262-1266. doi: 10.1093/humrep/deaa064. PMID: 32424401; PMCID: PMC8453394.
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[Alson R. Kilgore].

California medicine

GARLAND LH.
PMID: 13662854
Calif Med. 1959 Jun;90(6):453.

No abstract available.

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GARLAND LH. [Alson R. Kilgore]. Calif Med. 1959;90(6):453
GARLAND, L. H. (1959). [Alson R. Kilgore]. California medicine, 90(6), 453.
GARLAND, L H. "[Alson R. Kilgore]." California medicine vol. 90,6 (1959): 453.
GARLAND LH. [Alson R. Kilgore]. Calif Med. 1959 Jun;90(6):453. Undetermined. PMID: 13662854; PMCID: PMC1577655.
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Doctors afield: Sir Charles Tupper.

The New England journal of medicine

HARLAND WA.
PMID: 13632917
N Engl J Med. 1959 Mar 05;260(10):489-90. doi: 10.1056/NEJM195903052601009.

No abstract available.

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HARLAND WA. Doctors afield: Sir Charles Tupper. N Engl J Med. 1959;260(10):489-90doi: 10.1056/NEJM195903052601009.
HARLAND, W. A. (1959). Doctors afield: Sir Charles Tupper. The New England journal of medicine, 260(10), 489-90. https://doi.org/10.1056/NEJM195903052601009
HARLAND, W A. "Doctors afield: Sir Charles Tupper." The New England journal of medicine vol. 260,10 (1959): 489-90. doi: https://doi.org/10.1056/NEJM195903052601009
HARLAND WA. Doctors afield: Sir Charles Tupper. N Engl J Med. 1959 Mar 05;260(10):489-90. doi: 10.1056/NEJM195903052601009. PMID: 13632917.
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Robert Reid Newell; an appreciation.

Stanford medical bulletin

GARLAND LH.
PMID: 13486325
Stanford Med Bull. 1957 Aug;15(3):115-6.

No abstract available.

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GARLAND LH. Robert Reid Newell; an appreciation. Stanford Med Bull. 1957;15(3):115-6
GARLAND, L. H. (1957). Robert Reid Newell; an appreciation. Stanford medical bulletin, 15(3), 115-6.
GARLAND, L H. "Robert Reid Newell; an appreciation." Stanford medical bulletin vol. 15,3 (1957): 115-6.
GARLAND LH. Robert Reid Newell; an appreciation. Stanford Med Bull. 1957 Aug;15(3):115-6. PMID: 13486325.
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Broken Minds and Beaten Bodies: Cultures of Harm and the Management of Mental Illness in Mid- to Late Nineteenth-century English and Irish Prisons.

Social history of medicine : the journal of the Society for the Social History of Medicine

Cox C, Marland H.
PMID: 30515019
Soc Hist Med. 2018 Nov;31(4):688-710. doi: 10.1093/shm/hky038. Epub 2018 Jun 15.

This article explores the relationship between the prison and mental illness, focusing on the ways in which the system of separate confinement was associated with mental breakdown and how maintaining the integrity of prison discipline mitigated against prisoners obtaining...

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Cox C, Marland H. Broken Minds and Beaten Bodies: Cultures of Harm and the Management of Mental Illness in Mid- to Late Nineteenth-century English and Irish Prisons. Soc Hist Med. 2018;31(4):688-710doi: 10.1093/shm/hky038.
Cox, C., & Marland, H. (2018). Broken Minds and Beaten Bodies: Cultures of Harm and the Management of Mental Illness in Mid- to Late Nineteenth-century English and Irish Prisons. Social history of medicine : the journal of the Society for the Social History of Medicine, 31(4), 688-710. https://doi.org/10.1093/shm/hky038
Cox, Catherine, and Marland, Hilary. "Broken Minds and Beaten Bodies: Cultures of Harm and the Management of Mental Illness in Mid- to Late Nineteenth-century English and Irish Prisons." Social history of medicine : the journal of the Society for the Social History of Medicine vol. 31,4 (2018): 688-710. doi: https://doi.org/10.1093/shm/hky038
Cox C, Marland H. Broken Minds and Beaten Bodies: Cultures of Harm and the Management of Mental Illness in Mid- to Late Nineteenth-century English and Irish Prisons. Soc Hist Med. 2018 Nov;31(4):688-710. doi: 10.1093/shm/hky038. Epub 2018 Jun 15. PMID: 30515019; PMCID: PMC6263209.
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Showing 25 to 36 of 129 entries