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Showing 157 to 161 of 161 entries
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High-throughput functional variant screens via in vivo production of single-stranded DNA.

Proceedings of the National Academy of Sciences of the United States of America

Schubert MG, Goodman DB, Wannier TM, Kaur D, Farzadfard F, Lu TK, Shipman SL, Church GM.
PMID: 33906944
Proc Natl Acad Sci U S A. 2021 May 04;118(18). doi: 10.1073/pnas.2018181118.

Creating and characterizing individual genetic variants remains limited in scale, compared to the tremendous variation both existing in nature and envisioned by genome engineers. Here we introduce retron library recombineering (RLR), a methodology for high-throughput functional screens that surpasses...

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Schubert MG, Goodman DB, Wannier TM, et al. High-throughput functional variant screens via in vivo production of single-stranded DNA. Proc Natl Acad Sci U S A. 2021;118(18)doi: 10.1073/pnas.2018181118.
Schubert, M. G., Goodman, D. B., Wannier, T. M., Kaur, D., Farzadfard, F., Lu, T. K., Shipman, S. L., & Church, G. M. (2021). High-throughput functional variant screens via in vivo production of single-stranded DNA. Proceedings of the National Academy of Sciences of the United States of America, 118(18), . https://doi.org/10.1073/pnas.2018181118
Schubert, Max G, et al. "High-throughput functional variant screens via in vivo production of single-stranded DNA." Proceedings of the National Academy of Sciences of the United States of America vol. 118,18 (2021). doi: https://doi.org/10.1073/pnas.2018181118
Schubert MG, Goodman DB, Wannier TM, Kaur D, Farzadfard F, Lu TK, Shipman SL, Church GM. High-throughput functional variant screens via in vivo production of single-stranded DNA. Proc Natl Acad Sci U S A. 2021 May 04;118(18). doi: 10.1073/pnas.2018181118. PMID: 33906944; PMCID: PMC8106316.
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Abatacept for GVHD prophylaxis can reduce racial disparities by abrogating the impact of mismatching in unrelated donor stem cell transplantation.

Blood advances

Qayed M, Watkins B, Gillespie S, Bratrude B, Betz KM, Choi SW, Davis JH, Duncan C, Giller RH, Grimley M, Harris AC, Jacobsohn DA, Lalefar NR, Norkin M, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Waller EK, Langston A, Kean LS, Horan JT.
PMID: 34753172
Blood Adv. 2021 Nov 09; doi: 10.1182/bloodadvances.2021005208. Epub 2021 Nov 09.

No abstract available.

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Qayed M, Watkins B, Gillespie S, et al. Abatacept for GVHD prophylaxis can reduce racial disparities by abrogating the impact of mismatching in unrelated donor stem cell transplantation. Blood Adv. 2021;doi: 10.1182/bloodadvances.2021005208.
Qayed, M., Watkins, B., Gillespie, S., Bratrude, B., Betz, K. M., Choi, S. W., Davis, J. H., Duncan, C., Giller, R. H., Grimley, M., Harris, A. C., Jacobsohn, D. A., Lalefar, N. R., Norkin, M., Farhadfar, N., Pulsipher, M. A., Shenoy, S., Petrovic, A., Schultz, K. R., Yanik, G. A., Waller, E. K., Langston, A., Kean, L. S., & Horan, J. T. (2021). Abatacept for GVHD prophylaxis can reduce racial disparities by abrogating the impact of mismatching in unrelated donor stem cell transplantation. Blood advances, . https://doi.org/10.1182/bloodadvances.2021005208
Qayed, Muna, et al. "Abatacept for GVHD prophylaxis can reduce racial disparities by abrogating the impact of mismatching in unrelated donor stem cell transplantation." Blood advances vol. (2021). doi: https://doi.org/10.1182/bloodadvances.2021005208
Qayed M, Watkins B, Gillespie S, Bratrude B, Betz KM, Choi SW, Davis JH, Duncan C, Giller RH, Grimley M, Harris AC, Jacobsohn DA, Lalefar NR, Norkin M, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Waller EK, Langston A, Kean LS, Horan JT. Abatacept for GVHD prophylaxis can reduce racial disparities by abrogating the impact of mismatching in unrelated donor stem cell transplantation. Blood Adv. 2021 Nov 09; doi: 10.1182/bloodadvances.2021005208. Epub 2021 Nov 09. PMID: 34753172.
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Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation.

Nature communications

Stender EGP, Ray S, Norrild RK, Larsen JA, Petersen D, Farzadfard A, Galvagnion C, Jensen H, Buell AK.
PMID: 34911929
Nat Commun. 2021 Dec 15;12(1):7289. doi: 10.1038/s41467-021-27433-y.

Liquid-liquid phase separation or LLPS of proteins is a field of mounting importance and the value of quantitative kinetic and thermodynamic characterization of LLPS is increasingly recognized. We present a method, Capflex, which allows rapid and accurate quantification of...

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Stender EGP, Ray S, Norrild RK, et al. Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation. Nat Commun. 2021;12(1):7289doi: 10.1038/s41467-021-27433-y.
Stender, E. G. P., Ray, S., Norrild, R. K., Larsen, J. A., Petersen, D., Farzadfard, A., Galvagnion, C., Jensen, H., & Buell, A. K. (2021). Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation. Nature communications, 12(1), 7289. https://doi.org/10.1038/s41467-021-27433-y
Stender, Emil G P, et al. "Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation." Nature communications vol. 12,1 (2021): 7289. doi: https://doi.org/10.1038/s41467-021-27433-y
Stender EGP, Ray S, Norrild RK, Larsen JA, Petersen D, Farzadfard A, Galvagnion C, Jensen H, Buell AK. Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation. Nat Commun. 2021 Dec 15;12(1):7289. doi: 10.1038/s41467-021-27433-y. PMID: 34911929; PMCID: PMC8674230.
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Variation in the Proportion of Adults in Need of Blood Pressure-Lowering Medications by Hypertension Care Guideline in Low- and Middle-Income Countries: A Cross-Sectional Study of 1 037 215 Individuals From 50 Nationally Representative Surveys.

Circulation

Sudharsanan N, Theilmann M, Kirschbaum TK, Manne-Goehler J, Azadnajafabad S, Bovet P, Chen S, Damasceno A, De Neve JW, Dorobantu M, Ebert C, Farzadfar F, Gathecha G, Gurung MS, Jamshidi K, Jørgensen JMA, Labadarios D, Lemp J, Lunet N, Mwangi JK, Moghaddam SS, Bahendeka SK, Zhumadilov Z, Bärnighausen T, Vollmer S, Atun R, Davies JI, Geldsetzer P.
PMID: 33554610
Circulation. 2021 Mar 09;143(10):991-1001. doi: 10.1161/CIRCULATIONAHA.120.051620. Epub 2021 Feb 08.

BACKGROUND: Current hypertension guidelines vary substantially in their definition of who should be offered blood pressure-lowering medications. Understanding the effect of guideline choice on the proportion of adults who require treatment is crucial for planning and scaling up hypertension...

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Sudharsanan N, Theilmann M, Kirschbaum TK, et al. Variation in the Proportion of Adults in Need of Blood Pressure-Lowering Medications by Hypertension Care Guideline in Low- and Middle-Income Countries: A Cross-Sectional Study of 1 037 215 Individuals From 50 Nationally Representative Surveys. Circulation. 2021;143(10):991-1001doi: 10.1161/CIRCULATIONAHA.120.051620.
Sudharsanan, N., Theilmann, M., Kirschbaum, T. K., Manne-Goehler, J., Azadnajafabad, S., Bovet, P., Chen, S., Damasceno, A., De Neve, J. W., Dorobantu, M., Ebert, C., Farzadfar, F., Gathecha, G., Gurung, M. S., Jamshidi, K., Jørgensen, J. M. A., Labadarios, D., Lemp, J., Lunet, N., Mwangi, J. K., Moghaddam, S. S., Bahendeka, S. K., Zhumadilov, Z., Bärnighausen, T., Vollmer, S., Atun, R., Davies, J. I., & Geldsetzer, P. (2021). Variation in the Proportion of Adults in Need of Blood Pressure-Lowering Medications by Hypertension Care Guideline in Low- and Middle-Income Countries: A Cross-Sectional Study of 1 037 215 Individuals From 50 Nationally Representative Surveys. Circulation, 143(10), 991-1001. https://doi.org/10.1161/CIRCULATIONAHA.120.051620
Sudharsanan, Nikkil, et al. "Variation in the Proportion of Adults in Need of Blood Pressure-Lowering Medications by Hypertension Care Guideline in Low- and Middle-Income Countries: A Cross-Sectional Study of 1 037 215 Individuals From 50 Nationally Representative Surveys." Circulation vol. 143,10 (2021): 991-1001. doi: https://doi.org/10.1161/CIRCULATIONAHA.120.051620
Sudharsanan N, Theilmann M, Kirschbaum TK, Manne-Goehler J, Azadnajafabad S, Bovet P, Chen S, Damasceno A, De Neve JW, Dorobantu M, Ebert C, Farzadfar F, Gathecha G, Gurung MS, Jamshidi K, Jørgensen JMA, Labadarios D, Lemp J, Lunet N, Mwangi JK, Moghaddam SS, Bahendeka SK, Zhumadilov Z, Bärnighausen T, Vollmer S, Atun R, Davies JI, Geldsetzer P. Variation in the Proportion of Adults in Need of Blood Pressure-Lowering Medications by Hypertension Care Guideline in Low- and Middle-Income Countries: A Cross-Sectional Study of 1 037 215 Individuals From 50 Nationally Representative Surveys. Circulation. 2021 Mar 09;143(10):991-1001. doi: 10.1161/CIRCULATIONAHA.120.051620. Epub 2021 Feb 08. PMID: 33554610; PMCID: PMC7940589.
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Glycemic Index (GI) Values for Major Sources of Dietary Carbohydrates in Iran.

International journal of endocrinology and metabolism

Kazemi F, Danaei G, Farzadfar F, Malik V, Parsaeian M, Pouraram H, Zamaninour N, Rahmani J, Dorosty Motlagh AR.
PMID: 33257904
Int J Endocrinol Metab. 2020 Jun 27;18(3):e99793. doi: 10.5812/ijem.99793. eCollection 2020 Jul.

BACKGROUND: The glycemic index (GI) values of staple foods are not available in a standardized method in Iran.OBJECTIVES: The aim of this study was to measure the GI values of the major carbohydrate sources in a typical Iranian diet.METHODS:...

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Kazemi F, Danaei G, Farzadfar F, et al. Glycemic Index (GI) Values for Major Sources of Dietary Carbohydrates in Iran. Int J Endocrinol Metab. 2020;18(3):e99793doi: 10.5812/ijem.99793.
Kazemi, F., Danaei, G., Farzadfar, F., Malik, V., Parsaeian, M., Pouraram, H., Zamaninour, N., Rahmani, J., & Dorosty Motlagh, A. R. (2020). Glycemic Index (GI) Values for Major Sources of Dietary Carbohydrates in Iran. International journal of endocrinology and metabolism, 18(3), e99793. https://doi.org/10.5812/ijem.99793
Kazemi, Fatemeh, et al. "Glycemic Index (GI) Values for Major Sources of Dietary Carbohydrates in Iran." International journal of endocrinology and metabolism vol. 18,3 (2020): e99793. doi: https://doi.org/10.5812/ijem.99793
Kazemi F, Danaei G, Farzadfar F, Malik V, Parsaeian M, Pouraram H, Zamaninour N, Rahmani J, Dorosty Motlagh AR. Glycemic Index (GI) Values for Major Sources of Dietary Carbohydrates in Iran. Int J Endocrinol Metab. 2020 Jun 27;18(3):e99793. doi: 10.5812/ijem.99793. eCollection 2020 Jul. PMID: 33257904; PMCID: PMC7695225.
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Showing 157 to 161 of 161 entries