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Showing 109 to 116 of 116 entries
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The demographic and serological characteristics of COVID-19 convalescent plasma donors: Identification of basic criteria for optimal donor selection.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

Fazeli A, Sharifi S, Mohammadi S, Bahraini M, Arabkhazaeli A, Jelveh N, Eshghi P.
PMID: 34774440
Transfus Apher Sci. 2021 Oct 29;103302. doi: 10.1016/j.transci.2021.103302. Epub 2021 Oct 29.

BACKGROUND AND OBJECTIVES: Convalescent plasma has attracted significant attention as a therapeutic option against infectious agents for more than a century. In March 2020, the use of Convalescent COVID-19 plasma (CCP) as a new research drug for COVID-19 treatment...

Extracellular vesicle research in reproductive science- Paving the way for clinical achievements.

Biology of reproduction

Aleksejeva E, Zarovni N, Dissanayake K, Godakumara K, Vigano P, Fazeli A, Jaakma Ü, Salumets A.
PMID: 34982163
Biol Reprod. 2022 Jan 04; doi: 10.1093/biolre/ioab245. Epub 2022 Jan 04.

Mammalian conception involves a multitude of reciprocal interactions via a molecular dialogue between mother and conceptus. Extracellular vesicles (EVs) are secreted membrane-encapsulated particles that mediate cell-to-cell communication in various contexts. EVs, which are present in seminal, follicular, oviductal, and...

Improvement of thermostability of cholesterol oxidase from streptomyces Sp. SA-COO by random mutagenesis.

Protein expression and purification

Fazaeli A, Fana SE, Golestani A, Aminian M.
PMID: 34863881
Protein Expr Purif. 2021 Dec 01;191:106028. doi: 10.1016/j.pep.2021.106028. Epub 2021 Dec 01.

To enhance the thermal stability of Streptomyces Sp. SA-COO cholesterol oxidase, random mutagenesis was used. A random mutant library was generated using two types of error-prone PCR (single step and serial dilution) and two mutants (ChOA-M1 and ChOA-M2) with...

SIO: A Spatioimageomics Pipeline to Identify Prognostic Biomarkers Associated with the Ovarian Tumor Microenvironment.

Cancers

Zhu Y, Ferri-Borgogno S, Sheng J, Yeung TL, Burks JK, Cappello P, Jazaeri AA, Kim JH, Han GH, Birrer MJ, Mok SC, Wong STC.
PMID: 33917869
Cancers (Basel). 2021 Apr 08;13(8). doi: 10.3390/cancers13081777.

Stromal and immune cells in the tumor microenvironment (TME) have been shown to directly affect high-grade serous ovarian cancer (HGSC) malignant phenotypes, however, how these cells interact to influence HGSC patients' survival remains largely unknown. To investigate the cell-cell...

Pembrolizumab in vaginal and vulvar squamous cell carcinoma: a case series from a phase II basket trial.

Scientific reports

How JA, Jazaeri AA, Soliman PT, Fleming ND, Gong J, Piha-Paul SA, Janku F, Stephen B, Naing A.
PMID: 33574401
Sci Rep. 2021 Feb 11;11(1):3667. doi: 10.1038/s41598-021-83317-7.

Vaginal and vulvar squamous cell carcinoma (SCC) are rare tumors that can be challenging to treat in the recurrent or metastatic setting. We present a case series of patients with vaginal or vulvar SCC who were treated with single-agent...

Years of life lost (YLL) associated with COVID-19 deaths in Khorasan-RAZAVI province, Iran.

Journal of public health (Oxford, England)

Yousefi M, Fazaeli S, Mohammad-Pour S.
PMID: 34927698
J Public Health (Oxf). 2021 Dec 20; doi: 10.1093/pubmed/fdab392. Epub 2021 Dec 20.

BACKGROUND: The number of deaths among people with coronavirus disease 2019 (COVID-19) does not show the true impact of the disease on communities. Therefore, this study aimed to calculate years of life lost (YLL) due to premature death in...

Modification of Homologous Recombination Deficiency Score Threshold and Association with Long-Term Survival in Epithelial Ovarian Cancer.

Cancers

How JA, Jazaeri AA, Fellman B, Daniels MS, Penn S, Solimeno C, Yuan Y, Schmeler K, Lanchbury JS, Timms K, Lu KH, Yates MS.
PMID: 33668244
Cancers (Basel). 2021 Feb 24;13(5). doi: 10.3390/cancers13050946.

New therapies, such as poly-ADP ribose polymerase inhibitors (PARPi), and immunotherapy treatments have generated great interest in enhancing individualized molecular profiling of epithelial ovarian cancer (EOC) to improve management of the disease. In EOC patients, putative biomarkers for homologous...

Improvement of thermostability of cholesterol oxidase from streptomyces Sp. SA-COO by random mutagenesis.

Protein expression and purification

Fazaeli A, Fana SE, Golestani A, Aminian M.
PMID: 34863881
Protein Expr Purif. 2022 Mar;191:106028. doi: 10.1016/j.pep.2021.106028. Epub 2021 Dec 01.

To enhance the thermal stability of Streptomyces Sp. SA-COO cholesterol oxidase, random mutagenesis was used. A random mutant library was generated using two types of error-prone PCR (single step and serial dilution) and two mutants (ChOA-M1 and ChOA-M2) with...

Showing 109 to 116 of 116 entries