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Showing 13 to 24 of 30 entries
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Reply to Chu, et al.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Zhang B, Huaman MA, Fichtenbaum CJ, Longenecker CT.
PMID: 34181726
Clin Infect Dis. 2021 Jun 28; doi: 10.1093/cid/ciab592. Epub 2021 Jun 28.

No abstract available.

Elevated Circulating Concentrations of Interferon-Gamma in Latent Tuberculosis Infection.

Pathogens & immunity

Huaman MA, Deepe GS, Fichtenbaum CJ.
PMID: 27853753
Pathog Immun. 2016 Fall-Winter;1(2):291-303. doi: 10.20411/pai.v1i2.149.

BACKGROUND: Latent tuberculosis infection (LTBI) has been associated with increased immune activation. We assessed circulating concentrations of interferon-gamma in persons with LTBI.METHODS: We used the 2011-2012 National Health Nutritional Examination Survey (NHANES) to identify adults with and without LTBI...

Assessment of Obesity and Cardiometabolic Status by Integrase Inhibitor Use in REPRIEVE: A Propensity-Weighted Analysis of a Multinational Primary Cardiovascular Prevention Cohort of People With Human Immunodeficiency Virus.

Open forum infectious diseases

Kileel EM, Lo J, Malvestutto C, Fitch KV, Zanni MV, Fichtenbaum CJ, Overton ET, Okeke NL, Kumar P, Joao E, Aberg JA, Martinez E, Currier JS, Douglas PS, Ribaudo HJ, Grinspoon SK.
PMID: 34888395
Open Forum Infect Dis. 2021 Nov 20;8(12):ofab537. doi: 10.1093/ofid/ofab537. eCollection 2021 Dec.

BACKGROUND: Emerging data demonstrate that the use of integrase inhibitor (INSTI)-based antiretroviral treatment (ART) is associated with increased weight, but the cardiometabolic health consequences of increased weight remains poorly understood.METHODS: This analysis examined INSTI use (>6 months) at entry...

Autoimmune Global Amnesia as Manifestation of AMPAR Encephalitis and Neuropathologic Findings.

Neurology(R) neuroimmunology & neuroinflammation

Ricken G, Zrzavy T, Macher S, Altmann P, Troger J, Falk KK, Kiefer A, Fichtenbaum A, Mitulovic G, Kubista H, Wandinger KP, Rommer P, Bartsch T, Berger T, Weber J, Leypoldt F, Höftberger R.
PMID: 34016735
Neurol Neuroimmunol Neuroinflamm. 2021 May 20;8(4). doi: 10.1212/NXI.0000000000001019. Print 2021 Jul.

OBJECTIVE: To report an unusual clinical phenotype of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) encephalitis and describe associated neuropathologic findings.METHODS: We retrospectively investigated 3 AMPAR encephalitis patients with autoimmune global hippocampal amnesia using comprehensive cognitive and neuropsychologic assessment, antibody testing by...

A Randomized, Placebo-Controlled Trial Assessing the Effect of VISBIOME ES Probiotic in People With HIV on Antiretroviral Therapy.

Open forum infectious diseases

Presti RM, Yeh E, Williams B, Landay A, Jacobson JM, Wilson C, Fichtenbaum CJ, Utay NS, Dube MP, Klingman KL, Estes JD, Flynn JK, Loftin A, Brenchley JM, Andrade A, Kitch DW, Overton ET.
PMID: 34888397
Open Forum Infect Dis. 2021 Dec 07;8(12):ofab550. doi: 10.1093/ofid/ofab550. eCollection 2021 Dec.

BACKGROUND: A5350, a phase II, randomized, double-blind study, evaluated the safety and tolerability of the probiotic Visbiome Extra Strength (ES) over 24 weeks and measured effects on inflammation and intestinal barrier function.METHODS: The primary outcome was change in soluble...

A Randomized Study of the Impact of a Corneal Pre-Cut During Cataract Surgery on Wound Architecture and Corneal Astigmatism.

Ophthalmology and therapy

Doeller B, Hirnschall N, Fichtenbaum M, Nguyen PM, Varsits R, Findl O.
PMID: 33709325
Ophthalmol Ther. 2021 Jun;10(2):313-320. doi: 10.1007/s40123-021-00339-0. Epub 2021 Mar 11.

INTRODUCTION: The aim of the current study was to assess the effect of a 600-µm corneal pre-cut on wound architecture and its impact on surgically induced astigmatism. The images were acquired intraoperatively and postoperatively with high-resolution spectral-domain optical coherence...

Lipoprotein Changes in HIV-Infected Antiretroviral-Naïve Individuals after Starting Antiretroviral Therapy: ACTG Study A5152s Stein: Lipoprotein Changes on Antiretroviral Therapy.

Journal of clinical lipidology

Stein JH, Komarow L, Cotter BR, Currier JS, Dubé MP, Fichtenbaum CJ, Gerschenson M, Mitchell CK, Murphy RL, Squires K, Parker RA, Torriani FJ.
PMID: 19956354
J Clin Lipidol. 2008 Dec;2(6):464-471. doi: 10.1016/j.jacl.2008.08.442.

BACKGROUND: Dyslipidemia is a frequent complication of antiretroviral therapy (ART) for patients with human immunodeficiency virus infection (HIV). The effects of ART on lipoproteins are less well-understood, and have not been investigated in a prospective study where assignment to...

Inflammatory Markers Associated with Coronary Heart Disease in Persons with HIV Infection.

Current infectious disease reports

Fichtenbaum CJ.
PMID: 21308460
Curr Infect Dis Rep. 2011 Feb;13(1):94-101. doi: 10.1007/s11908-010-0153-9.

Coronary heart disease (CHD) is an inflammatory process that takes decades to develop. In HIV-seronegative persons, high-sensitivity C-reactive protein is a biologic marker of CHD risk. HIV infection induces chronic inflammation, despite adequate suppression of HIV replication with antiretroviral...

Entrustment and mapping of observable practice activities for resident assessment.

Journal of general internal medicine

Warm EJ, Mathis BR, Held JD, Pai S, Tolentino J, Ashbrook L, Lee CK, Lee D, Wood S, Fichtenbaum CJ, Schauer D, Munyon R, Mueller C.
PMID: 24557518
J Gen Intern Med. 2014 Aug;29(8):1177-82. doi: 10.1007/s11606-014-2801-5. Epub 2014 Feb 21.

Entrustable Professional Activities (EPAs) and the Next Accreditation System reporting milestones reduce general competencies into smaller evaluable parts. However, some EPAs and reporting milestones may be too broad to use as direct assessment tools. We describe our internal medicine...

Assessment of Coronary Artery Disease With Computed Tomography Angiography and Inflammatory and Immune Activation Biomarkers Among Adults With HIV Eligible for Primary Cardiovascular Prevention.

JAMA network open

Hoffmann U, Lu MT, Foldyna B, Zanni MV, Karady J, Taron J, Zhai BK, Burdo T, Fitch KV, Kileel EM, Williams K, Fichtenbaum CJ, Overton ET, Malvestutto C, Aberg J, Currier J, Sponseller CA, Melbourne K, Floris-Moore M, Van Dam C, Keefer MC, Koletar SL, Douglas PS, Ribaudo H, Mayrhofer T, Grinspoon SK.
PMID: 34185068
JAMA Netw Open. 2021 Jun 01;4(6):e2114923. doi: 10.1001/jamanetworkopen.2021.14923.

IMPORTANCE: Cardiovascular disease (CVD) is increased among people with HIV (PWH), but little is known regarding the prevalence and extent of coronary artery disease (CAD) and associated biological factors in PWH with low to moderate traditional CVD risk.OBJECTIVES: To...

Corrigendum to: Patterns of Antiretroviral Therapy Use and Immunologic Profiles at Enrollment in the REPRIEVE Trial.

The Journal of infectious diseases

Fichtenbaum CJ, Ribaudo HJ, Leon-Cruz J, Overton ET, Zanni MV, Malvestutto CD, Aberg JA, Kileel EM, Fitch KV, Van Schalkwyk M, Kumarasamy N, Martinez E, Santos BR, Joseph Y, Lo J, Siminski S, Melbourne K, Sponseller CA, Desvigne-Nickens P, Bloomfield GS, Currier JS, Hoffmann U, Douglas PS, Grinspoon SK.
PMID: 33068427
J Infect Dis. 2021 Feb 03;223(2):352. doi: 10.1093/infdis/jiaa594.

No abstract available.

Serum Bovine Immunoglobulins Improve Inflammation and Gut Barrier Function in Persons with HIV and Enteropathy on Suppressive ART.

Pathogens & immunity

Utay NS, Somasunderam A, Hinkle JE, Petschow BW, Detzel CJ, Somsouk M, Fichtenbaum CJ, Weaver EM, Shaw AL, Asmuth DM.
PMID: 31139758
Pathog Immun. 2019 May 03;4(1):124-146. doi: 10.20411/pai.v4i1.276. eCollection 2019.

BACKGROUND: Systemic inflammation persists in chronic HIV infection and is associated with increased rates of non-AIDS events such as cardiovascular and liver disease. Increased gut permeability and systemic exposure to microbial products are key drivers of this inflammation. Serum-derived...

Showing 13 to 24 of 30 entries