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Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth.

Cancer research

Cook DR, Kang M, Martin TD, Galanko JA, Loeza GH, Trembath DG, Justilien V, Pickering KA, Vincent DF, Jarosch A, Jurmeister P, Waters AM, Hibshman PS, Campbell AD, Ford CA, Keku TO, Yeh JJ, Lee MS, Cox AD, Fields AP, Sandler RS, Sansom OJ, Sers C, Schaefer A, Der CJ.
PMID: 34737214
Cancer Res. 2021 Nov 04; doi: 10.1158/0008-5472.CAN-20-4218. Epub 2021 Nov 04.

ECT2 is an activator of RHO GTPases that is essential for cytokinesis. Additionally, ECT2 was identified as an oncoprotein when expressed ectopically in NIH/3T3 fibroblasts. However, oncogenic activation of ECT2 resulted from N-terminal truncation, and such truncated ECT2 proteins...

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Cook DR, Kang M, Martin TD, et al. Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth. Cancer Res. 2021;doi: 10.1158/0008-5472.CAN-20-4218.
Cook, D. R., Kang, M., Martin, T. D., Galanko, J. A., Loeza, G. H., Trembath, D. G., Justilien, V., Pickering, K. A., Vincent, D. F., Jarosch, A., Jurmeister, P., Waters, A. M., Hibshman, P. S., Campbell, A. D., Ford, C. A., Keku, T. O., Yeh, J. J., Lee, M. S., Cox, A. D., Fields, A. P., Sandler, R. S., Sansom, O. J., Sers, C., Schaefer, A., & Der, C. J. (2021). Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth. Cancer research, . https://doi.org/10.1158/0008-5472.CAN-20-4218
Cook, Danielle R, et al. "Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth." Cancer research vol. (2021). doi: https://doi.org/10.1158/0008-5472.CAN-20-4218
Cook DR, Kang M, Martin TD, Galanko JA, Loeza GH, Trembath DG, Justilien V, Pickering KA, Vincent DF, Jarosch A, Jurmeister P, Waters AM, Hibshman PS, Campbell AD, Ford CA, Keku TO, Yeh JJ, Lee MS, Cox AD, Fields AP, Sandler RS, Sansom OJ, Sers C, Schaefer A, Der CJ. Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth. Cancer Res. 2021 Nov 04; doi: 10.1158/0008-5472.CAN-20-4218. Epub 2021 Nov 04. PMID: 34737214.
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Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension.

Journal of the mechanical behavior of biomedical materials

Werbner B, Lee M, Lee A, Yang L, Habib M, Fields AJ, O'Connell GD.
PMID: 34864399
J Mech Behav Biomed Mater. 2021 Nov 20;126:104992. doi: 10.1016/j.jmbbm.2021.104992. Epub 2021 Nov 20.

Advanced-glycation end products (AGEs) are known to accumulate in biological tissues with age and at an accelerated rate in patients with diabetes and chronic kidney disease. Clinically, diabetes has been linked to increased frequency and severity of back pain,...

Cite
Werbner B, Lee M, Lee A, et al. Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. J Mech Behav Biomed Mater. 2021;126:104992doi: 10.1016/j.jmbbm.2021.104992.
Werbner, B., Lee, M., Lee, A., Yang, L., Habib, M., Fields, A. J., & O'Connell, G. D. (2021). Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. Journal of the mechanical behavior of biomedical materials, 126104992. https://doi.org/10.1016/j.jmbbm.2021.104992
Werbner, Benjamin, et al. "Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension." Journal of the mechanical behavior of biomedical materials vol. 126 (2021): 104992. doi: https://doi.org/10.1016/j.jmbbm.2021.104992
Werbner B, Lee M, Lee A, Yang L, Habib M, Fields AJ, O'Connell GD. Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. J Mech Behav Biomed Mater. 2021 Nov 20;126:104992. doi: 10.1016/j.jmbbm.2021.104992. Epub 2021 Nov 20. PMID: 34864399.
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Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a.

PLoS genetics

Fields CJ, Li L, Hiers NM, Li T, Sheng P, Huda T, Shan J, Gay L, Gu T, Bian J, Kilberg MS, Renne R, Xie M.
PMID: 34914716
PLoS Genet. 2021 Dec 16;17(12):e1009934. doi: 10.1371/journal.pgen.1009934. eCollection 2021 Dec.

MicroRNAs (miRNA) are short non-coding RNAs widely implicated in gene regulation. Most metazoan miRNAs utilize the RNase III enzymes Drosha and Dicer for biogenesis. One notable exception is the RNA polymerase II transcription start sites (TSS) miRNAs whose biogenesis...

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Fields CJ, Li L, Hiers NM, et al. Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a. PLoS Genet. 2021;17(12):e1009934doi: 10.1371/journal.pgen.1009934.
Fields, C. J., Li, L., Hiers, N. M., Li, T., Sheng, P., Huda, T., Shan, J., Gay, L., Gu, T., Bian, J., Kilberg, M. S., Renne, R., & Xie, M. (2021). Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a. PLoS genetics, 17(12), e1009934. https://doi.org/10.1371/journal.pgen.1009934
Fields, Christopher J, et al. "Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a." PLoS genetics vol. 17,12 (2021): e1009934. doi: https://doi.org/10.1371/journal.pgen.1009934
Fields CJ, Li L, Hiers NM, Li T, Sheng P, Huda T, Shan J, Gay L, Gu T, Bian J, Kilberg MS, Renne R, Xie M. Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a. PLoS Genet. 2021 Dec 16;17(12):e1009934. doi: 10.1371/journal.pgen.1009934. eCollection 2021 Dec. PMID: 34914716; PMCID: PMC8675727.
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Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension.

Journal of the mechanical behavior of biomedical materials

Werbner B, Lee M, Lee A, Yang L, Habib M, Fields AJ, O'Connell GD.
PMID: 34864399
J Mech Behav Biomed Mater. 2021 Nov 20;126:104992. doi: 10.1016/j.jmbbm.2021.104992. Epub 2021 Nov 20.

Advanced-glycation end products (AGEs) are known to accumulate in biological tissues with age and at an accelerated rate in patients with diabetes and chronic kidney disease. Clinically, diabetes has been linked to increased frequency and severity of back pain,...

Cite
Werbner B, Lee M, Lee A, et al. Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. J Mech Behav Biomed Mater. 2021;126:104992doi: 10.1016/j.jmbbm.2021.104992.
Werbner, B., Lee, M., Lee, A., Yang, L., Habib, M., Fields, A. J., & O'Connell, G. D. (2021). Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. Journal of the mechanical behavior of biomedical materials, 126104992. https://doi.org/10.1016/j.jmbbm.2021.104992
Werbner, Benjamin, et al. "Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension." Journal of the mechanical behavior of biomedical materials vol. 126 (2021): 104992. doi: https://doi.org/10.1016/j.jmbbm.2021.104992
Werbner B, Lee M, Lee A, Yang L, Habib M, Fields AJ, O'Connell GD. Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. J Mech Behav Biomed Mater. 2021 Nov 20;126:104992. doi: 10.1016/j.jmbbm.2021.104992. Epub 2021 Nov 20. PMID: 34864399.
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Telemedicine-based sleep services for a complex child: optimizing care during a pandemic and beyond.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Donskoy I, Loghmanee D, Fields BG, Troester M, Martin W.
PMID: 34402782
J Clin Sleep Med. 2022 Jan 01;18(1):325-327. doi: 10.5664/jcsm.9616.

A 12-year-old male with nonverbal autism and morbid obesity was referred to a pediatric sleep center during the SARS-CoV-2 pandemic for complaints of snoring with tonsillar hypertrophy and difficulty falling asleep. Due to social challenges, the family had not...

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Donskoy I, Loghmanee D, Fields BG, et al. Telemedicine-based sleep services for a complex child: optimizing care during a pandemic and beyond. J Clin Sleep Med. 2022;18(1):325-327doi: 10.5664/jcsm.9616.
Donskoy, I., Loghmanee, D., Fields, B. G., Troester, M., & Martin, W. (2022). Telemedicine-based sleep services for a complex child: optimizing care during a pandemic and beyond. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 18(1), 325-327. https://doi.org/10.5664/jcsm.9616
Donskoy, Innessa, et al. "Telemedicine-based sleep services for a complex child: optimizing care during a pandemic and beyond." Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine vol. 18,1 (2022): 325-327. doi: https://doi.org/10.5664/jcsm.9616
Donskoy I, Loghmanee D, Fields BG, Troester M, Martin W. Telemedicine-based sleep services for a complex child: optimizing care during a pandemic and beyond. J Clin Sleep Med. 2022 Jan 01;18(1):325-327. doi: 10.5664/jcsm.9616. PMID: 34402782.
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Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth.

Cancer research

Cook DR, Kang M, Martin TD, Galanko JA, Loeza GH, Trembath DG, Justilien V, Pickering KA, Vincent DF, Jarosch A, Jurmeister P, Waters AM, Hibshman PS, Campbell AD, Ford CA, Keku TO, Yeh JJ, Lee MS, Cox AD, Fields AP, Sandler RS, Sansom OJ, Sers C, Schaefer A, Der CJ.
PMID: 34737214
Cancer Res. 2022 Jan 01;82(1):90-104. doi: 10.1158/0008-5472.CAN-20-4218. Epub 2021 Nov 04.

ECT2 is an activator of RHO GTPases that is essential for cytokinesis. In addition, ECT2 was identified as an oncoprotein when expressed ectopically in NIH/3T3 fibroblasts. However, oncogenic activation of ECT2 resulted from N-terminal truncation, and such truncated ECT2...

Cite
Cook DR, Kang M, Martin TD, et al. Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth. Cancer Res. 2021;82(1):90-104doi: 10.1158/0008-5472.CAN-20-4218.
Cook, D. R., Kang, M., Martin, T. D., Galanko, J. A., Loeza, G. H., Trembath, D. G., Justilien, V., Pickering, K. A., Vincent, D. F., Jarosch, A., Jurmeister, P., Waters, A. M., Hibshman, P. S., Campbell, A. D., Ford, C. A., Keku, T. O., Yeh, J. J., Lee, M. S., Cox, A. D., Fields, A. P., Sandler, R. S., Sansom, O. J., Sers, C., Schaefer, A., & Der, C. J. (2022). Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth. Cancer research, 82(1), 90-104. https://doi.org/10.1158/0008-5472.CAN-20-4218
Cook, Danielle R, et al. "Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth." Cancer research vol. 82,1 (2022): 90-104. doi: https://doi.org/10.1158/0008-5472.CAN-20-4218
Cook DR, Kang M, Martin TD, Galanko JA, Loeza GH, Trembath DG, Justilien V, Pickering KA, Vincent DF, Jarosch A, Jurmeister P, Waters AM, Hibshman PS, Campbell AD, Ford CA, Keku TO, Yeh JJ, Lee MS, Cox AD, Fields AP, Sandler RS, Sansom OJ, Sers C, Schaefer A, Der CJ. Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth. Cancer Res. 2022 Jan 01;82(1):90-104. doi: 10.1158/0008-5472.CAN-20-4218. Epub 2021 Nov 04. PMID: 34737214.
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Survival Outcomes for Malignant Peritoneal Mesothelioma at Academic Versus Community Hospitals.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Welten VM, Fields AC, Malizia RA, Yoo J, Irani JL, Goldberg JE, Bleday R, Melnitchouk N.
PMID: 34287781
J Gastrointest Surg. 2022 Jan;26(1):161-170. doi: 10.1007/s11605-021-05084-0. Epub 2021 Jul 21.

BACKGROUND: Malignant peritoneal mesothelioma is a rare disease with poor outcomes. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy is the cornerstone of therapy. We aim to compare outcomes of malignant peritoneal mesothelioma treated at academic versus community hospitals.METHODS: This was...

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Welten VM, Fields AC, Malizia RA, et al. Survival Outcomes for Malignant Peritoneal Mesothelioma at Academic Versus Community Hospitals. J Gastrointest Surg. 2021;26(1):161-170doi: 10.1007/s11605-021-05084-0.
Welten, V. M., Fields, A. C., Malizia, R. A., Yoo, J., Irani, J. L., Goldberg, J. E., Bleday, R., & Melnitchouk, N. (2022). Survival Outcomes for Malignant Peritoneal Mesothelioma at Academic Versus Community Hospitals. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 26(1), 161-170. https://doi.org/10.1007/s11605-021-05084-0
Welten, Vanessa M, et al. "Survival Outcomes for Malignant Peritoneal Mesothelioma at Academic Versus Community Hospitals." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract vol. 26,1 (2022): 161-170. doi: https://doi.org/10.1007/s11605-021-05084-0
Welten VM, Fields AC, Malizia RA, Yoo J, Irani JL, Goldberg JE, Bleday R, Melnitchouk N. Survival Outcomes for Malignant Peritoneal Mesothelioma at Academic Versus Community Hospitals. J Gastrointest Surg. 2022 Jan;26(1):161-170. doi: 10.1007/s11605-021-05084-0. Epub 2021 Jul 21. PMID: 34287781.
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Equivalence class formation when responding is separated from sample and comparison stimuli: Working memory, priming, and sorting.

Journal of the experimental analysis of behavior

Fields L, Doran E, Foxe JJ.
PMID: 33289111
J Exp Anal Behav. 2020 Dec 02; doi: 10.1002/jeab.651. Epub 2020 Dec 02.

The experiment determined whether equivalence class formation required overlap of comparison stimuli and responding. Each trial contained a sample first, a single, nonoverlapping comparison second, and a nonoverlapping response-window (RW) third, during which the participant made one of two...

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Fields L, Doran E, Foxe JJ. Equivalence class formation when responding is separated from sample and comparison stimuli: Working memory, priming, and sorting. J Exp Anal Behav. 2020;doi: 10.1002/jeab.651.
Fields, L., Doran, E., & Foxe, J. J. (2020). Equivalence class formation when responding is separated from sample and comparison stimuli: Working memory, priming, and sorting. Journal of the experimental analysis of behavior, . https://doi.org/10.1002/jeab.651
Fields, Lanny, et al. "Equivalence class formation when responding is separated from sample and comparison stimuli: Working memory, priming, and sorting." Journal of the experimental analysis of behavior vol. (2020). doi: https://doi.org/10.1002/jeab.651
Fields L, Doran E, Foxe JJ. Equivalence class formation when responding is separated from sample and comparison stimuli: Working memory, priming, and sorting. J Exp Anal Behav. 2020 Dec 02; doi: 10.1002/jeab.651. Epub 2020 Dec 02. PMID: 33289111.
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Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension.

Journal of the mechanical behavior of biomedical materials

Werbner B, Lee M, Lee A, Yang L, Habib M, Fields AJ, O'Connell GD.
PMID: 34864399
J Mech Behav Biomed Mater. 2021 Nov 20;126:104992. doi: 10.1016/j.jmbbm.2021.104992. Epub 2021 Nov 20.

Advanced-glycation end products (AGEs) are known to accumulate in biological tissues with age and at an accelerated rate in patients with diabetes and chronic kidney disease. Clinically, diabetes has been linked to increased frequency and severity of back pain,...

Cite
Werbner B, Lee M, Lee A, et al. Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. J Mech Behav Biomed Mater. 2021;126:104992doi: 10.1016/j.jmbbm.2021.104992.
Werbner, B., Lee, M., Lee, A., Yang, L., Habib, M., Fields, A. J., & O'Connell, G. D. (2021). Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. Journal of the mechanical behavior of biomedical materials, 126104992. https://doi.org/10.1016/j.jmbbm.2021.104992
Werbner, Benjamin, et al. "Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension." Journal of the mechanical behavior of biomedical materials vol. 126 (2021): 104992. doi: https://doi.org/10.1016/j.jmbbm.2021.104992
Werbner B, Lee M, Lee A, Yang L, Habib M, Fields AJ, O'Connell GD. Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. J Mech Behav Biomed Mater. 2021 Nov 20;126:104992. doi: 10.1016/j.jmbbm.2021.104992. Epub 2021 Nov 20. PMID: 34864399.
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Showing 229 to 237 of 237 entries