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Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study.

Alzheimer's & dementia (Amsterdam, Netherlands)

Petersen ME, Zhang F, Schupf N, Krinsky-McHale SJ, Hall J, Mapstone M, Cheema A, Silverman W, Lott I, Rafii MS, Handen B, Klunk W, Head E, Christian B, Foroud T, Lai F, Rosas HD, Zaman S, Ances BM, Wang MC, Tycko B, Lee JH, O'Bryant S.
PMID: 32626817
Alzheimers Dement (Amst). 2020 Jun 30;12(1):e12039. doi: 10.1002/dad2.12039. eCollection 2020.

INTRODUCTION: Previously generated serum and plasma proteomic profiles were examined among adults with Down syndrome (DS) to determine whether these profiles could discriminate those with mild cognitive impairment (MCI-DS) and Alzheimer's disease (DS-AD) from those cognitively stable (CS).METHODS: Data...

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Petersen ME, Zhang F, Schupf N, et al. Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study. Alzheimers Dement (Amst). 2020;12(1):e12039doi: 10.1002/dad2.12039.
Petersen, M. E., Zhang, F., Schupf, N., Krinsky-McHale, S. J., Hall, J., Mapstone, M., Cheema, A., Silverman, W., Lott, I., Rafii, M. S., Handen, B., Klunk, W., Head, E., Christian, B., Foroud, T., Lai, F., Rosas, H. D., Zaman, S., Ances, B. M., Wang, M. C., Tycko, B., Lee, J. H., O'Bryant, S. (2020). Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study. Alzheimer's & dementia (Amsterdam, Netherlands), 12(1), e12039. https://doi.org/10.1002/dad2.12039
Petersen, Melissa E, et al. "Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study." Alzheimer's & dementia (Amsterdam, Netherlands) vol. 12,1 (2020): e12039. doi: https://doi.org/10.1002/dad2.12039
Petersen ME, Zhang F, Schupf N, Krinsky-McHale SJ, Hall J, Mapstone M, Cheema A, Silverman W, Lott I, Rafii MS, Handen B, Klunk W, Head E, Christian B, Foroud T, Lai F, Rosas HD, Zaman S, Ances BM, Wang MC, Tycko B, Lee JH, O'Bryant S. Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study. Alzheimers Dement (Amst). 2020 Jun 30;12(1):e12039. doi: 10.1002/dad2.12039. eCollection 2020. PMID: 32626817; PMCID: PMC7327223.
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Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome.

Alzheimer's & dementia (Amsterdam, Netherlands)

Henson RL, Doran E, Christian BT, Handen BL, Klunk WE, Lai F, Lee JH, Rosas HD, Schupf N, Zaman SH, Lott IT, Fagan AM.
PMID: 32671183
Alzheimers Dement (Amst). 2020 Jul 09;12(1):e12057. doi: 10.1002/dad2.12057. eCollection 2020.

INTRODUCTION: Virtually all individuals with Down syndrome (DS) will develop Alzheimer's disease (AD) pathology by age 40. Cerebrospinal fluid (CSF) biomarkers have characterized AD pathology in cohorts of late-onset AD (LOAD) and autosomal-dominant AD (ADAD). Few studies have evaluated...

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Henson RL, Doran E, Christian BT, et al. Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome. Alzheimers Dement (Amst). 2020;12(1):e12057doi: 10.1002/dad2.12057.
Henson, R. L., Doran, E., Christian, B. T., Handen, B. L., Klunk, W. E., Lai, F., Lee, J. H., Rosas, H. D., Schupf, N., Zaman, S. H., Lott, I. T., & Fagan, A. M. (2020). Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands), 12(1), e12057. https://doi.org/10.1002/dad2.12057
Henson, Rachel L, et al. "Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome." Alzheimer's & dementia (Amsterdam, Netherlands) vol. 12,1 (2020): e12057. doi: https://doi.org/10.1002/dad2.12057
Henson RL, Doran E, Christian BT, Handen BL, Klunk WE, Lai F, Lee JH, Rosas HD, Schupf N, Zaman SH, Lott IT, Fagan AM. Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome. Alzheimers Dement (Amst). 2020 Jul 09;12(1):e12057. doi: 10.1002/dad2.12057. eCollection 2020. PMID: 32671183; PMCID: PMC7346867.
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Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase.

European journal of organic chemistry

Zacharova MK, Tulloch LB, Gould ER, Fraser AL, King EF, Menzies SK, Smith TK, Florence GJ.
PMID: 31598093
European J Org Chem. 2019 Sep 01;2019(31):5434-5440. doi: 10.1002/ejoc.201900541. Epub 2019 May 29.

The protozoan parasites

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Zacharova MK, Tulloch LB, Gould ER, et al. Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase. European J Org Chem. 2019;2019(31):5434-5440doi: 10.1002/ejoc.201900541.
Zacharova, M. K., Tulloch, L. B., Gould, E. R., Fraser, A. L., King, E. F., Menzies, S. K., Smith, T. K., & Florence, G. J. (2019). Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase. European journal of organic chemistry, 2019(31), 5434-5440. https://doi.org/10.1002/ejoc.201900541
Zacharova, Marija K, et al. "Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase." European journal of organic chemistry vol. 2019,31 (2019): 5434-5440. doi: https://doi.org/10.1002/ejoc.201900541
Zacharova MK, Tulloch LB, Gould ER, Fraser AL, King EF, Menzies SK, Smith TK, Florence GJ. Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase. European J Org Chem. 2019 Sep 01;2019(31):5434-5440. doi: 10.1002/ejoc.201900541. Epub 2019 May 29. PMID: 31598093; PMCID: PMC6774295.
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Heat Transfer and Residence Time Distribution in Plug Flow Continuous Oscillatory Baffled Crystallizers.

ACS omega

Briggs NEB, McGinty J, McCabe C, Raval V, Sefcik J, Florence AJ.
PMID: 34308066
ACS Omega. 2021 Jul 09;6(28):18352-18363. doi: 10.1021/acsomega.1c02215. eCollection 2021 Jul 20.

Heat transfer coefficients in a continuous oscillatory baffled crystallizer (COBC) with a nominal internal diameter of 15 mm have been determined as a function of flow and oscillatory conditions typically used under processing conditions. Residence time distribution measurements show...

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Briggs NEB, McGinty J, McCabe C, et al. Heat Transfer and Residence Time Distribution in Plug Flow Continuous Oscillatory Baffled Crystallizers. ACS Omega. 2021;6(28):18352-18363doi: 10.1021/acsomega.1c02215.
Briggs, N. E. B., McGinty, J., McCabe, C., Raval, V., Sefcik, J., & Florence, A. J. (2021). Heat Transfer and Residence Time Distribution in Plug Flow Continuous Oscillatory Baffled Crystallizers. ACS omega, 6(28), 18352-18363. https://doi.org/10.1021/acsomega.1c02215
Briggs, Naomi E B, et al. "Heat Transfer and Residence Time Distribution in Plug Flow Continuous Oscillatory Baffled Crystallizers." ACS omega vol. 6,28 (2021): 18352-18363. doi: https://doi.org/10.1021/acsomega.1c02215
Briggs NEB, McGinty J, McCabe C, Raval V, Sefcik J, Florence AJ. Heat Transfer and Residence Time Distribution in Plug Flow Continuous Oscillatory Baffled Crystallizers. ACS Omega. 2021 Jul 09;6(28):18352-18363. doi: 10.1021/acsomega.1c02215. eCollection 2021 Jul 20. PMID: 34308066; PMCID: PMC8296600.
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Email Patient-Provider Communication and Cancer Screenings Among US Adults: Cross-sectional Study.

JMIR cancer

Kindratt TB, Allicock M, Atem F, Dallo FJ, Balasubramanian BA.
PMID: 34328421
JMIR Cancer. 2021 Jul 30;7(3):e23790. doi: 10.2196/23790.

BACKGROUND: The growth of electronic medical records and use of patient portals have allowed for patients and health care providers to communicate via email and direct messaging between health care visits. Email patient-provider communication (PPC) may enhance traditional face-to-face...

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Kindratt TB, Allicock M, Atem F, et al. Email Patient-Provider Communication and Cancer Screenings Among US Adults: Cross-sectional Study. JMIR Cancer. 2021;7(3):e23790doi: 10.2196/23790.
Kindratt, T. B., Allicock, M., Atem, F., Dallo, F. J., & Balasubramanian, B. A. (2021). Email Patient-Provider Communication and Cancer Screenings Among US Adults: Cross-sectional Study. JMIR cancer, 7(3), e23790. https://doi.org/10.2196/23790
Kindratt, Tiffany B, et al. "Email Patient-Provider Communication and Cancer Screenings Among US Adults: Cross-sectional Study." JMIR cancer vol. 7,3 (2021): e23790. doi: https://doi.org/10.2196/23790
Kindratt TB, Allicock M, Atem F, Dallo FJ, Balasubramanian BA. Email Patient-Provider Communication and Cancer Screenings Among US Adults: Cross-sectional Study. JMIR Cancer. 2021 Jul 30;7(3):e23790. doi: 10.2196/23790. PMID: 34328421; PMCID: PMC8367146.
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Overview of imaging in adult- and childhood-onset Takayasu arteritis.

The Journal of rheumatology

Aeschlimann FA, Raimondi F, Leiner T, Aquaro GD, Saadoun D, Grotenhuis HB.
PMID: 34853087
J Rheumatol. 2021 Dec 01; doi: 10.3899/jrheum.210368. Epub 2021 Dec 01.

Takayasu Arteritis is an idiopathic large vessel vasculitis, that affects young adults and children and can lead to ischemia and end-organ damage. Vascular imaging is crucial for diagnosis, assessment of disease extent and management of the disease. In this...

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Aeschlimann FA, Raimondi F, Leiner T, et al. Overview of imaging in adult- and childhood-onset Takayasu arteritis. J Rheumatol. 2021;doi: 10.3899/jrheum.210368.
Aeschlimann, F. A., Raimondi, F., Leiner, T., Aquaro, G. D., Saadoun, D., & Grotenhuis, H. B. (2021). Overview of imaging in adult- and childhood-onset Takayasu arteritis. The Journal of rheumatology, . https://doi.org/10.3899/jrheum.210368
Aeschlimann, Florence A, et al. "Overview of imaging in adult- and childhood-onset Takayasu arteritis." The Journal of rheumatology vol. (2021). doi: https://doi.org/10.3899/jrheum.210368
Aeschlimann FA, Raimondi F, Leiner T, Aquaro GD, Saadoun D, Grotenhuis HB. Overview of imaging in adult- and childhood-onset Takayasu arteritis. J Rheumatol. 2021 Dec 01; doi: 10.3899/jrheum.210368. Epub 2021 Dec 01. PMID: 34853087.
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Evolving ischemic stroke subtypes in 15 years: A hospital-based observational study.

International journal of stroke : official journal of the International Stroke Society

Ip B, Au L, Chan A, Fan F, Ip V, Ma SH, Ma K, Mok V, Lau A, Leng X, Leung H, Wong A, Abrigo J, Wong J, Yu S, Wong L, Soo Y, Leung T.
PMID: 33724087
Int J Stroke. 2021 Apr 07;17474930211005953. doi: 10.1177/17474930211005953. Epub 2021 Apr 07.

BACKGROUND: Depicting the time trends of ischemic stroke subtypes may inform healthcare resource allocation on etiology-based stroke prevention and treatment.AIM: To reveal the evolving ischemic stroke subtypes from 2004 to 2018.METHODS: We determined the stroke etiologies of consecutive first-ever...

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Ip B, Au L, Chan A, et al. Evolving ischemic stroke subtypes in 15 years: A hospital-based observational study. Int J Stroke. 2021;17474930211005953doi: 10.1177/17474930211005953.
Ip, B., Au, L., Chan, A., Fan, F., Ip, V., Ma, S. H., Ma, K., Mok, V., Lau, A., Leng, X., Leung, H., Wong, A., Abrigo, J., Wong, J., Yu, S., Wong, L., Soo, Y., & Leung, T. (2021). Evolving ischemic stroke subtypes in 15 years: A hospital-based observational study. International journal of stroke : official journal of the International Stroke Society, 17474930211005953. https://doi.org/10.1177/17474930211005953
Ip, Bonaventure, et al. "Evolving ischemic stroke subtypes in 15 years: A hospital-based observational study." International journal of stroke : official journal of the International Stroke Society vol. (2021): 17474930211005953. doi: https://doi.org/10.1177/17474930211005953
Ip B, Au L, Chan A, Fan F, Ip V, Ma SH, Ma K, Mok V, Lau A, Leng X, Leung H, Wong A, Abrigo J, Wong J, Yu S, Wong L, Soo Y, Leung T. Evolving ischemic stroke subtypes in 15 years: A hospital-based observational study. Int J Stroke. 2021 Apr 07;17474930211005953. doi: 10.1177/17474930211005953. Epub 2021 Apr 07. PMID: 33724087.
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Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models.

Brain sciences

Hom CL, Kirby KA, Ricks-Oddie J, Keator DB, Krinsky-McHale SJ, Pulsifer MB, Rosas HD, Lai F, Schupf N, Lott IT, Silverman W.
PMID: 34573242
Brain Sci. 2021 Sep 16;11(9). doi: 10.3390/brainsci11091220.

Accurate identification of the prodromal stage of Alzheimer's disease (AD), known as mild cognitive impairment (MCI), in adults with Down syndrome (MCI-DS) has been challenging because there are no established diagnostic criteria that can be applied for people with...

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Hom CL, Kirby KA, Ricks-Oddie J, et al. Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models. Brain Sci. 2021;11(9)doi: 10.3390/brainsci11091220.
Hom, C. L., Kirby, K. A., Ricks-Oddie, J., Keator, D. B., Krinsky-McHale, S. J., Pulsifer, M. B., Rosas, H. D., Lai, F., Schupf, N., Lott, I. T., & Silverman, W. (2021). Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models. Brain sciences, 11(9), . https://doi.org/10.3390/brainsci11091220
Hom, Christy L, et al. "Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models." Brain sciences vol. 11,9 (2021). doi: https://doi.org/10.3390/brainsci11091220
Hom CL, Kirby KA, Ricks-Oddie J, Keator DB, Krinsky-McHale SJ, Pulsifer MB, Rosas HD, Lai F, Schupf N, Lott IT, Silverman W. Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models. Brain Sci. 2021 Sep 16;11(9). doi: 10.3390/brainsci11091220. PMID: 34573242; PMCID: PMC8471085.
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Altered connectivity of the default mode network in cognitively stable adults with Down syndrome: "Accelerated aging" or a prelude to Alzheimer's disease?.

Alzheimer's & dementia (Amsterdam, Netherlands)

Rosas HD, Lewis LR, Mercaldo ND, Nasr S, Brickman AM, Siless V, Yassa M, Sathishkumar M, Lott I, Schupf N, Silverman W, Lai F.
PMID: 34027014
Alzheimers Dement (Amst). 2021 May 20;13(1):e12105. doi: 10.1002/dad2.12105. eCollection 2021.

INTRODUCTION: Most individuals with Down syndrome (DS) have the neuropathological changes of Alzheimer's disease (AD) by age 40 and will have developed dementia by age 60. Alterations of the intrinsic connectivity of the default mode network (DMN) are associated...

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Rosas HD, Lewis LR, Mercaldo ND, et al. Altered connectivity of the default mode network in cognitively stable adults with Down syndrome: "Accelerated aging" or a prelude to Alzheimer's disease?. Alzheimers Dement (Amst). 2021;13(1):e12105doi: 10.1002/dad2.12105.
Rosas, H. D., Lewis, L. R., Mercaldo, N. D., Nasr, S., Brickman, A. M., Siless, V., Yassa, M., Sathishkumar, M., Lott, I., Schupf, N., Silverman, W., Lai, F. (2021). Altered connectivity of the default mode network in cognitively stable adults with Down syndrome: "Accelerated aging" or a prelude to Alzheimer's disease?. Alzheimer's & dementia (Amsterdam, Netherlands), 13(1), e12105. https://doi.org/10.1002/dad2.12105
Rosas, H Diana, et al. "Altered connectivity of the default mode network in cognitively stable adults with Down syndrome: "Accelerated aging" or a prelude to Alzheimer's disease?." Alzheimer's & dementia (Amsterdam, Netherlands) vol. 13,1 (2021): e12105. doi: https://doi.org/10.1002/dad2.12105
Rosas HD, Lewis LR, Mercaldo ND, Nasr S, Brickman AM, Siless V, Yassa M, Sathishkumar M, Lott I, Schupf N, Silverman W, Lai F. Altered connectivity of the default mode network in cognitively stable adults with Down syndrome: "Accelerated aging" or a prelude to Alzheimer's disease?. Alzheimers Dement (Amst). 2021 May 20;13(1):e12105. doi: 10.1002/dad2.12105. eCollection 2021. PMID: 34027014; PMCID: PMC8136300.
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Cognitive Disability Among Arab Americans by Nativity Status and Arrival Year: Lack of Evidence for the Healthy Migrant Effect.

Journal of racial and ethnic health disparities

Kindratt TB, Dallo FJ, Zahodne LB.
PMID: 34505264
J Racial Ethn Health Disparities. 2021 Sep 09; doi: 10.1007/s40615-021-01144-y. Epub 2021 Sep 09.

Limited research exists on cognitive disabilities among Arab Americans, especially as it relates to arrival year among the foreign-born. The objectives of this study were to estimate the age- and sex-adjusted prevalence and associations of cognitive disability by (1)...

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Kindratt TB, Dallo FJ, Zahodne LB. Cognitive Disability Among Arab Americans by Nativity Status and Arrival Year: Lack of Evidence for the Healthy Migrant Effect. J Racial Ethn Health Disparities. 2021;doi: 10.1007/s40615-021-01144-y.
Kindratt, T. B., Dallo, F. J., & Zahodne, L. B. (2021). Cognitive Disability Among Arab Americans by Nativity Status and Arrival Year: Lack of Evidence for the Healthy Migrant Effect. Journal of racial and ethnic health disparities, . https://doi.org/10.1007/s40615-021-01144-y
Kindratt, Tiffany B, et al. "Cognitive Disability Among Arab Americans by Nativity Status and Arrival Year: Lack of Evidence for the Healthy Migrant Effect." Journal of racial and ethnic health disparities vol. (2021). doi: https://doi.org/10.1007/s40615-021-01144-y
Kindratt TB, Dallo FJ, Zahodne LB. Cognitive Disability Among Arab Americans by Nativity Status and Arrival Year: Lack of Evidence for the Healthy Migrant Effect. J Racial Ethn Health Disparities. 2021 Sep 09; doi: 10.1007/s40615-021-01144-y. Epub 2021 Sep 09. PMID: 34505264.
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Best Practices for Engaging Pregnant and Postpartum Women at Risk of Substance Use in Longitudinal Research Studies: a Qualitative Examination of Participant Preferences.

Adversity and resilience science

Beasley LO, Ciciolla L, Jespersen JE, Chiaf AL, Schmidt M, Shreffler KM, Breslin FJ, Bakhireva LN, Sanjuan PM, Stephen JM, Coles CD, Chambers CD, Kable JA, Leeman L, Singer LT, Zellner J, Morris AS, Croff JM.
PMID: 33134976
Advers Resil Sci. 2020 Oct 28;1-12. doi: 10.1007/s42844-020-00019-1. Epub 2020 Oct 28.

There are significant barriers in engaging pregnant and postpartum women that are considered high-risk (e.g., those experiencing substance use and/or substance use disorders (SUD)) into longitudinal research studies. To improve recruitment and retention of this population in studies spanning...

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Beasley LO, Ciciolla L, Jespersen JE, et al. Best Practices for Engaging Pregnant and Postpartum Women at Risk of Substance Use in Longitudinal Research Studies: a Qualitative Examination of Participant Preferences. Advers Resil Sci. 2020;1-12doi: 10.1007/s42844-020-00019-1.
Beasley, L. O., Ciciolla, L., Jespersen, J. E., Chiaf, A. L., Schmidt, M., Shreffler, K. M., Breslin, F. J., Bakhireva, L. N., Sanjuan, P. M., Stephen, J. M., Coles, C. D., Chambers, C. D., Kable, J. A., Leeman, L., Singer, L. T., Zellner, J., Morris, A. S., & Croff, J. M. (2020). Best Practices for Engaging Pregnant and Postpartum Women at Risk of Substance Use in Longitudinal Research Studies: a Qualitative Examination of Participant Preferences. Adversity and resilience science, 1-12. https://doi.org/10.1007/s42844-020-00019-1
Beasley, Lana O, et al. "Best Practices for Engaging Pregnant and Postpartum Women at Risk of Substance Use in Longitudinal Research Studies: a Qualitative Examination of Participant Preferences." Adversity and resilience science vol. (2020): 1-12. doi: https://doi.org/10.1007/s42844-020-00019-1
Beasley LO, Ciciolla L, Jespersen JE, Chiaf AL, Schmidt M, Shreffler KM, Breslin FJ, Bakhireva LN, Sanjuan PM, Stephen JM, Coles CD, Chambers CD, Kable JA, Leeman L, Singer LT, Zellner J, Morris AS, Croff JM. Best Practices for Engaging Pregnant and Postpartum Women at Risk of Substance Use in Longitudinal Research Studies: a Qualitative Examination of Participant Preferences. Advers Resil Sci. 2020 Oct 28;1-12. doi: 10.1007/s42844-020-00019-1. Epub 2020 Oct 28. PMID: 33134976; PMCID: PMC7592139.
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Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation.

Mucosal immunology

Motta JP, Rolland C, Edir A, Florence AC, Sagnat D, Bonnart C, Rousset P, Guiraud L, Quaranta-Nicaise M, Mas E, Bonnet D, Verdu EF, McKay DM, Buscail E, Alric L, Vergnolle N, Deraison C.
PMID: 33674762
Mucosal Immunol. 2021 May;14(3):667-678. doi: 10.1038/s41385-021-00375-w. Epub 2021 Mar 05.

Imbalance between proteases and their inhibitors plays a crucial role in the development of Inflammatory Bowel Diseases (IBD). Increased elastolytic activity is observed in the colon of patients suffering from IBD. Here, we aimed at identifying the players involved...

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Motta JP, Rolland C, Edir A, et al. Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation. Mucosal Immunol. 2021;14(3):667-678doi: 10.1038/s41385-021-00375-w.
Motta, J. P., Rolland, C., Edir, A., Florence, A. C., Sagnat, D., Bonnart, C., Rousset, P., Guiraud, L., Quaranta-Nicaise, M., Mas, E., Bonnet, D., Verdu, E. F., McKay, D. M., Buscail, E., Alric, L., Vergnolle, N., & Deraison, C. (2021). Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation. Mucosal immunology, 14(3), 667-678. https://doi.org/10.1038/s41385-021-00375-w
Motta, Jean-Paul, et al. "Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation." Mucosal immunology vol. 14,3 (2021): 667-678. doi: https://doi.org/10.1038/s41385-021-00375-w
Motta JP, Rolland C, Edir A, Florence AC, Sagnat D, Bonnart C, Rousset P, Guiraud L, Quaranta-Nicaise M, Mas E, Bonnet D, Verdu EF, McKay DM, Buscail E, Alric L, Vergnolle N, Deraison C. Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation. Mucosal Immunol. 2021 May;14(3):667-678. doi: 10.1038/s41385-021-00375-w. Epub 2021 Mar 05. PMID: 33674762; PMCID: PMC8075934.
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