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Showing 253 to 255 of 255 entries
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Combinatorial Pharmacogenomic Testing Improves Outcomes for Older Adults With Depression.

Focus (American Psychiatric Publishing)

Forester BP, Parikh SV, Weisenbach S, Ajilore O, Vahia I, Rothschild AJ, Thase ME, Dunlop BW, DeBattista C, Conway CR, Shelton RC, Macaluso M, Li J, Traxler P, Logan J, Brown L, Dechairo B, Greden JF.
PMID: 34483773
Focus (Am Psychiatr Publ). 2021 Jan;19(1):76-85. doi: 10.1176/appi.focus.19107. Epub 2021 Jan 25.

(Reprinted with permission from

Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1.

Cell chemical biology

Persaud R, Li SC, Chao JD, Forestieri R, Donohue E, Balgi AD, Zheng X, Chao JT, Yashiroda Y, Yoshimura M, Loewen CJR, Gingras AC, Boone C, Av-Gay Y, Roberge M, Andersen RJ.
PMID: 34520745
Cell Chem Biol. 2021 Sep 11; doi: 10.1016/j.chembiol.2021.07.017. Epub 2021 Sep 11.

The pathogen Mycobacterium tuberculosis (Mtb) evades the innate immune system by interfering with autophagy and phagosomal maturation in macrophages, and, as a result, small molecule stimulation of autophagy represents a host-directed therapeutics (HDTs) approach for treatment of tuberculosis (TB)....

Low Dose Lithium Treatment of Behavioral Complications in Alzheimer's Disease: Lit-AD Randomized Clinical Trial.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Devanand DP, Crocco E, Forester BP, Husain MM, Lee S, Vahia IV, Andrews H, Simon-Pearson L, Imran N, Luca L, Huey ED, Deliyannides DA, Pelton GH.
PMID: 34059401
Am J Geriatr Psychiatry. 2022 Jan;30(1):32-42. doi: 10.1016/j.jagp.2021.04.014. Epub 2021 May 12.

BACKGROUND: A case series suggested efficacy for lithium to treat agitation in dementia, but no placebo-controlled trials have been conducted.OBJECTIVES: To evaluate low-dose lithium treatment of agitation in Alzheimer's disease (AD).METHOD: In a four-site trial, patients with AD and...

Showing 253 to 255 of 255 entries