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Showing 541 to 546 of 546 entries
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Cost-effectiveness of an 8-week supervised education and exercise therapy programme for knee and hip osteoarthritis: a pre-post analysis of 16 255 patients participating in Good Life with osteoArthritis in Denmark (GLA:D).

BMJ open

Grønne DT, Roos EM, Ibsen R, Kjellberg J, Skou ST.
PMID: 34903537
BMJ Open. 2021 Dec 13;11(12):e049541. doi: 10.1136/bmjopen-2021-049541.

OBJECTIVES: To evaluate 1-year cost-effectiveness of an 8-week supervised education and exercise programme delivered in primary care to patients with symptomatic knee or hip osteoarthritis (OA).DESIGN: A registry-based pre-post study linking patient-level data from the Good Life with osteoArthritis...

Trehalose, a natural disaccharide, reduces stroke occurrence in the stroke-prone spontaneously hypertensive rat.

Pharmacological research

Forte M, Marchitti S, Cotugno M, Di Nonno F, Stanzione R, Bianchi F, Schirone L, Schiavon S, Vecchio D, Sarto G, Scioli M, Raffa S, Tocci G, Relucenti M, Torrisi MR, Valenti V, Versaci F, Vecchione C, Volpe M, Frati G, Rubattu S, Sciarretta S.
PMID: 34500062
Pharmacol Res. 2021 Nov;173:105875. doi: 10.1016/j.phrs.2021.105875. Epub 2021 Sep 07.

Cerebrovascular disease, a frequent complication of hypertension, is a major public health issue for which novel therapeutic and preventive approaches are needed. Autophagy activation is emerging as a potential therapeutic and preventive strategy toward stroke. Among usual activators of...

Diagnostic reasoning: relationships among expertise, accuracy, and ways that nurse practitioner students self-explain.

Diagnosis (Berlin, Germany)

Burt L, Finnegan L, Schwartz A, Corte C, Quinn L, Clark L, Corbridge S.
PMID: 33901388
Diagnosis (Berl). 2021 Apr 26; doi: 10.1515/dx-2020-0137. Epub 2021 Apr 26.

OBJECTIVES: To improve diagnostic ability, educators should employ multifocal strategies. One promising strategy is self-explanation, the purposeful technique of generating self-directed explanations during problem-solving. Students self-explain information in ways that range from simple restatements to multidimensional thoughts. Successful problem-solvers...

Atraumatic femoral head necrosis: a biomechanical, histological and radiological examination compared to primary hip osteoarthritis.

Archives of orthopaedic and trauma surgery

Hofmann A, Fischer B, Schleifenbaum S, Kurz S, Edel M, Borte G, Lehmann G, Roth A.
PMID: 33970320
Arch Orthop Trauma Surg. 2021 May 10; doi: 10.1007/s00402-021-03890-4. Epub 2021 May 10.

INTRODUCTION: Atraumatic necrosis of the femoral head (AFHN) is a common disease with an incidence of 5000-7000 middle-aged adults in Germany. There is no uniform consensus in the literature regarding the configuration of the bone in AFHN. The clinical...

Effects of exposure to single and multiple parabens on asthma development in an experimental mouse model and a prospective cohort study.

The Science of the total environment

Junge KM, Buchenauer L, Strunz S, Seiwert B, Thürmann L, Rolle-Kampczyk UE, Röder S, Borte M, Kiess W, von Bergen M, Simon JC, Zenclussen AC, Schöneberg T, Stangl GI, Herberth G, Lehmann I, Reemtsma T, Polte T.
PMID: 34973317
Sci Total Environ. 2021 Dec 30;814:152676. doi: 10.1016/j.scitotenv.2021.152676. Epub 2021 Dec 30.

Parabens are widely used preservatives present in consumer products like cosmetics and food. Although several epidemiological studies suggest that early-life exposure to parabens might alter the immune response and allergy risk in childhood, the evidence with respect to asthma...

The Implementation of Protocol-Based Utilization of Neuromuscular Blocking Agent Using Clinical Variables in Acute Respiratory Distress Syndrome Patients.

Critical care explorations

Hadique S, Badami V, Forte M, Kovacic N, Umer A, Shigle A, Gardo J, Sangani R.
PMID: 33786447
Crit Care Explor. 2021 Mar 19;3(3):e0371. doi: 10.1097/CCE.0000000000000371. eCollection 2021 Mar.

OBJECTIVES: The recent conflicting data on the mortality benefit of neuromuscular blocking agents in acute respiratory distress syndrome and the potential adverse effects of continuous neuromuscular blocking agent necessitates that these medications should be used judiciously with dose reduction...

Showing 541 to 546 of 546 entries