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Showing 25 to 36 of 180 entries
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Structure, function and pharmacology of human itch GPCRs.

Nature

Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL.
PMID: 34789874
Nature. 2021 Dec;600(7887):170-175. doi: 10.1038/s41586-021-04126-6. Epub 2021 Nov 17.

The MRGPRX family of receptors (MRGPRX1-4) is a family of mas-related G-protein-coupled receptors that have evolved relatively recently

Cite
Cao C, Kang HJ, Singh I, et al. Structure, function and pharmacology of human itch GPCRs. Nature. 2021;600(7887):170-175doi: 10.1038/s41586-021-04126-6.
Cao, C., Kang, H. J., Singh, I., Chen, H., Zhang, C., Ye, W., Hayes, B. W., Liu, J., Gumpper, R. H., Bender, B. J., Slocum, S. T., Krumm, B. E., Lansu, K., McCorvy, J. D., Kroeze, W. K., English, J. G., DiBerto, J. F., Olsen, R. H. J., Huang, X. P., Zhang, S., Liu, Y., Kim, K., Karpiak, J., Jan, L. Y., Abraham, S. N., Jin, J., Shoichet, B. K., Fay, J. F., & Roth, B. L. (2021). Structure, function and pharmacology of human itch GPCRs. Nature, 600(7887), 170-175. https://doi.org/10.1038/s41586-021-04126-6
Cao, Can, et al. "Structure, function and pharmacology of human itch GPCRs." Nature vol. 600,7887 (2021): 170-175. doi: https://doi.org/10.1038/s41586-021-04126-6
Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL. Structure, function and pharmacology of human itch GPCRs. Nature. 2021 Dec;600(7887):170-175. doi: 10.1038/s41586-021-04126-6. Epub 2021 Nov 17. PMID: 34789874.
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Outcomes of perineal urethrostomy for penile cancer: A 20-year international multicenter experience.

Urologic oncology

de Vries HM, Chipollini J, Slongo J, Boyd F, Korkes F, Albersen M, Roussel E, Zhu Y, Ye DW, Master V, Le TL, Johnstone PA, Muneer A, Brouwer OR, Spiess PE.
PMID: 34134926
Urol Oncol. 2021 Aug;39(8):500.e9-500.e13. doi: 10.1016/j.urolonc.2021.04.023. Epub 2021 Jun 13.

PURPOSE: Perineal urethrostomy (PU) is often the definitive form of urinary diversion in patients with locally-advanced or anatomically unfavorable penile cancer (PC) requiring total penectomy. Here, we report post-operative PU-related complications and PU stenosis rates after total penectomy with...

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de Vries HM, Chipollini J, Slongo J, et al. Outcomes of perineal urethrostomy for penile cancer: A 20-year international multicenter experience. Urol Oncol. 2021;39(8):500.e9-500.e13doi: 10.1016/j.urolonc.2021.04.023.
de Vries, H. M., Chipollini, J., Slongo, J., Boyd, F., Korkes, F., Albersen, M., Roussel, E., Zhu, Y., Ye, D. W., Master, V., Le, T. L., Johnstone, P. A., Muneer, A., Brouwer, O. R., & Spiess, P. E. (2021). Outcomes of perineal urethrostomy for penile cancer: A 20-year international multicenter experience. Urologic oncology, 39(8), 500.e9-500.e13. https://doi.org/10.1016/j.urolonc.2021.04.023
de Vries, Hielke M, et al. "Outcomes of perineal urethrostomy for penile cancer: A 20-year international multicenter experience." Urologic oncology vol. 39,8 (2021): 500.e9-500.e13. doi: https://doi.org/10.1016/j.urolonc.2021.04.023
de Vries HM, Chipollini J, Slongo J, Boyd F, Korkes F, Albersen M, Roussel E, Zhu Y, Ye DW, Master V, Le TL, Johnstone PA, Muneer A, Brouwer OR, Spiess PE. Outcomes of perineal urethrostomy for penile cancer: A 20-year international multicenter experience. Urol Oncol. 2021 Aug;39(8):500.e9-500.e13. doi: 10.1016/j.urolonc.2021.04.023. Epub 2021 Jun 13. PMID: 34134926.
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A life cycle alteration can correct molting defects in Caenorhabditis elegans.

Developmental biology

Binti S, Melinda RV, Joseph BB, Edeen PT, Miller SD, Fay DS.
PMID: 35038442
Dev Biol. 2022 Jan 14; doi: 10.1016/j.ydbio.2022.01.001. Epub 2022 Jan 14.

Molting is a widespread feature in the development of many invertebrates, including nematodes and arthropods. In Caenorhabditis elegans, the highly conserved protein kinases NEKL-2/NEK8/9 and NEKL-3/NEK6/7 (NEKLs) promote molting through their involvement in the uptake and intracellular trafficking of...

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Binti S, Melinda RV, Joseph BB, et al. A life cycle alteration can correct molting defects in Caenorhabditis elegans. Dev Biol. 2022;doi: 10.1016/j.ydbio.2022.01.001.
Binti, S., Melinda, R. V., Joseph, B. B., Edeen, P. T., Miller, S. D., & Fay, D. S. (2022). A life cycle alteration can correct molting defects in Caenorhabditis elegans. Developmental biology, . https://doi.org/10.1016/j.ydbio.2022.01.001
Binti, Shaonil, et al. "A life cycle alteration can correct molting defects in Caenorhabditis elegans." Developmental biology vol. (2022). doi: https://doi.org/10.1016/j.ydbio.2022.01.001
Binti S, Melinda RV, Joseph BB, Edeen PT, Miller SD, Fay DS. A life cycle alteration can correct molting defects in Caenorhabditis elegans. Dev Biol. 2022 Jan 14; doi: 10.1016/j.ydbio.2022.01.001. Epub 2022 Jan 14. PMID: 35038442.
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Structure, function and pharmacology of human itch GPCRs.

Nature

Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL.
PMID: 34789874
Nature. 2021 Dec;600(7887):170-175. doi: 10.1038/s41586-021-04126-6. Epub 2021 Nov 17.

The MRGPRX family of receptors (MRGPRX1-4) is a family of mas-related G-protein-coupled receptors that have evolved relatively recently

Cite
Cao C, Kang HJ, Singh I, et al. Structure, function and pharmacology of human itch GPCRs. Nature. 2021;600(7887):170-175doi: 10.1038/s41586-021-04126-6.
Cao, C., Kang, H. J., Singh, I., Chen, H., Zhang, C., Ye, W., Hayes, B. W., Liu, J., Gumpper, R. H., Bender, B. J., Slocum, S. T., Krumm, B. E., Lansu, K., McCorvy, J. D., Kroeze, W. K., English, J. G., DiBerto, J. F., Olsen, R. H. J., Huang, X. P., Zhang, S., Liu, Y., Kim, K., Karpiak, J., Jan, L. Y., Abraham, S. N., Jin, J., Shoichet, B. K., Fay, J. F., & Roth, B. L. (2021). Structure, function and pharmacology of human itch GPCRs. Nature, 600(7887), 170-175. https://doi.org/10.1038/s41586-021-04126-6
Cao, Can, et al. "Structure, function and pharmacology of human itch GPCRs." Nature vol. 600,7887 (2021): 170-175. doi: https://doi.org/10.1038/s41586-021-04126-6
Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL. Structure, function and pharmacology of human itch GPCRs. Nature. 2021 Dec;600(7887):170-175. doi: 10.1038/s41586-021-04126-6. Epub 2021 Nov 17. PMID: 34789874.
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Assessing Medicare Health Plan Performance in Serving Beneficiary Subpopulations.

Health care financing review

Cox DF, Langwell KM, Eckert B.
PMID: 25372773
Health Care Financ Rev. 2001;22(3):85-99.

In this analysis, the authors examined differences in managed care health plan performance ratings between selected subgroups of the Medicare population who may have exceptional health care needs (EHCNs) or may require special plan efforts to facilitate effective service...

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Cox DF, Langwell KM, Eckert B. Assessing Medicare Health Plan Performance in Serving Beneficiary Subpopulations. Health Care Financ Rev. 2001;22(3):85-99
Cox, D. F., Langwell, K. M., & Eckert, B. (2001). Assessing Medicare Health Plan Performance in Serving Beneficiary Subpopulations. Health care financing review, 22(3), 85-99.
Cox, Donald F, et al. "Assessing Medicare Health Plan Performance in Serving Beneficiary Subpopulations." Health care financing review vol. 22,3 (2001): 85-99.
Cox DF, Langwell KM, Eckert B. Assessing Medicare Health Plan Performance in Serving Beneficiary Subpopulations. Health Care Financ Rev. 2001;22(3):85-99. PMID: 25372773; PMCID: PMC4194703.
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Impact of radiation therapy on perineal urethrostomy for penile cancer.

Clinical and translational radiation oncology

A S Johnstone P, de Vries HM, Chipollini J, Daniel Grass G, Boyd F, Korkes F, Albersen M, Roussel E, Zhu Y, Ye DW, Master V, Le TL, Muneer A, Brouwer OR, Spiess PE.
PMID: 34430718
Clin Transl Radiat Oncol. 2021 Aug 09;30:84-87. doi: 10.1016/j.ctro.2021.08.005. eCollection 2021 Sep.

OBJECTIVE: A lack of demonstrated clinical benefit precludes radiotherapy (RT) from being recommended for pN1/pN2 penile cancer (PeCa) lesions; but it may be recommended in case of extranodal (pN3) disease or for positive resection margins. Perineal urethrostomy (PU) is...

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A S Johnstone P, de Vries HM, Chipollini J, et al. Impact of radiation therapy on perineal urethrostomy for penile cancer. Clin Transl Radiat Oncol. 2021;30:84-87doi: 10.1016/j.ctro.2021.08.005.
A S Johnstone, P., de Vries, H. M., Chipollini, J., Daniel Grass, G., Boyd, F., Korkes, F., Albersen, M., Roussel, E., Zhu, Y., Ye, D. W., Master, V., Le, T. L., Muneer, A., Brouwer, O. R., & Spiess, P. E. (2021). Impact of radiation therapy on perineal urethrostomy for penile cancer. Clinical and translational radiation oncology, 3084-87. https://doi.org/10.1016/j.ctro.2021.08.005
A S Johnstone, Peter, et al. "Impact of radiation therapy on perineal urethrostomy for penile cancer." Clinical and translational radiation oncology vol. 30 (2021): 84-87. doi: https://doi.org/10.1016/j.ctro.2021.08.005
A S Johnstone P, de Vries HM, Chipollini J, Daniel Grass G, Boyd F, Korkes F, Albersen M, Roussel E, Zhu Y, Ye DW, Master V, Le TL, Muneer A, Brouwer OR, Spiess PE. Impact of radiation therapy on perineal urethrostomy for penile cancer. Clin Transl Radiat Oncol. 2021 Aug 09;30:84-87. doi: 10.1016/j.ctro.2021.08.005. eCollection 2021 Sep. PMID: 34430718; PMCID: PMC8367760.
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How students experience and navigate transitions in undergraduate medical education: an application of Bourdieu's theoretical model.

Advances in health sciences education : theory and practice

Balmer DF, Richards BF, Varpio L.
PMID: 25633168
Adv Health Sci Educ Theory Pract. 2015 Oct;20(4):1073-85. doi: 10.1007/s10459-015-9588-y. Epub 2015 Jan 30.

Using Bourdieu's theoretical model as a lens for analysis, we sought to understand how students experience the undergraduate medical education (UME) milieu, focusing on how they navigate transitions from the preclinical phase, to the major clinical year (MCY), and...

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Balmer DF, Richards BF, Varpio L. How students experience and navigate transitions in undergraduate medical education: an application of Bourdieu's theoretical model. Adv Health Sci Educ Theory Pract. 2015;20(4):1073-85doi: 10.1007/s10459-015-9588-y.
Balmer, D. F., Richards, B. F., & Varpio, L. (2015). How students experience and navigate transitions in undergraduate medical education: an application of Bourdieu's theoretical model. Advances in health sciences education : theory and practice, 20(4), 1073-85. https://doi.org/10.1007/s10459-015-9588-y
Balmer, Dorene F, et al. "How students experience and navigate transitions in undergraduate medical education: an application of Bourdieu's theoretical model." Advances in health sciences education : theory and practice vol. 20,4 (2015): 1073-85. doi: https://doi.org/10.1007/s10459-015-9588-y
Balmer DF, Richards BF, Varpio L. How students experience and navigate transitions in undergraduate medical education: an application of Bourdieu's theoretical model. Adv Health Sci Educ Theory Pract. 2015 Oct;20(4):1073-85. doi: 10.1007/s10459-015-9588-y. Epub 2015 Jan 30. PMID: 25633168.
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A CDPK type protein kinase is involved in rice SPS light modulation.

Physiologia plantarum

Pagnussat GC, Fiol DF, Salerno GL.
PMID: 12060234
Physiol Plant. 2002 Jun;115(2):183-189. doi: 10.1034/j.1399-3054.2002.1150202.x.

A protein kinase activity that can phosphorylate and inactivate rice (Oryza sativa) sucrose-phosphate synthase (SPS; UDP-glucose: d-fructose-6-phosphate-2-glucosyl transferase, EC 2.4.1.14) was measured in extracts prepared from leaves exposed to light-dark transitions. Enzyme activity present in extracts from dark leaves...

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Pagnussat GC, Fiol DF, Salerno GL. A CDPK type protein kinase is involved in rice SPS light modulation. Physiol Plant. 2002;115(2):183-189doi: 10.1034/j.1399-3054.2002.1150202.x.
Pagnussat, G. C., Fiol, D. F., & Salerno, G. L. (2002). A CDPK type protein kinase is involved in rice SPS light modulation. Physiologia plantarum, 115(2), 183-189. https://doi.org/10.1034/j.1399-3054.2002.1150202.x
Pagnussat, Gabriela C, et al. "A CDPK type protein kinase is involved in rice SPS light modulation." Physiologia plantarum vol. 115,2 (2002): 183-189. doi: https://doi.org/10.1034/j.1399-3054.2002.1150202.x
Pagnussat GC, Fiol DF, Salerno GL. A CDPK type protein kinase is involved in rice SPS light modulation. Physiol Plant. 2002 Jun;115(2):183-189. doi: 10.1034/j.1399-3054.2002.1150202.x. PMID: 12060234.
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N3'-->P5' Oligodeoxyribonucleotide Phosphoramidates: A New Method of Synthesis Based on a Phosphoramidite Amine-Exchange Reaction.

The Journal of organic chemistry

Nelson JS, Fearon KL, Nguyen MQ, McCurdy SN, Frediani JE, Foy MF, Hirschbein BL.
PMID: 11671841
J Org Chem. 1997 Oct 17;62(21):7278-7287. doi: 10.1021/jo970801t.

A new method for the synthesis of N3'-->P5' phosphoramidate oligodeoxynucleotides is demonstrated. Described herein is the synthesis of the monomers utilized in the phosphoramidite amine-exchange process and the experimental details pertaining to this new mode of chain assembly. The...

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Nelson JS, Fearon KL, Nguyen MQ, et al. N3'-->P5' Oligodeoxyribonucleotide Phosphoramidates: A New Method of Synthesis Based on a Phosphoramidite Amine-Exchange Reaction. J Org Chem. 1997;62(21):7278-7287doi: 10.1021/jo970801t.
Nelson, J. S., Fearon, K. L., Nguyen, M. Q., McCurdy, S. N., Frediani, J. E., Foy, M. F., & Hirschbein, B. L. (1997). N3'-->P5' Oligodeoxyribonucleotide Phosphoramidates: A New Method of Synthesis Based on a Phosphoramidite Amine-Exchange Reaction. The Journal of organic chemistry, 62(21), 7278-7287. https://doi.org/10.1021/jo970801t
Nelson, Jeffrey S., et al. "N3'-->P5' Oligodeoxyribonucleotide Phosphoramidates: A New Method of Synthesis Based on a Phosphoramidite Amine-Exchange Reaction." The Journal of organic chemistry vol. 62,21 (1997): 7278-7287. doi: https://doi.org/10.1021/jo970801t
Nelson JS, Fearon KL, Nguyen MQ, McCurdy SN, Frediani JE, Foy MF, Hirschbein BL. N3'-->P5' Oligodeoxyribonucleotide Phosphoramidates: A New Method of Synthesis Based on a Phosphoramidite Amine-Exchange Reaction. J Org Chem. 1997 Oct 17;62(21):7278-7287. doi: 10.1021/jo970801t. PMID: 11671841.
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HDAC inhibitors suppressed small cell lung cancer cell growth and enhanced the suppressive effects of receptor-targeting cytotoxins via upregulating somatostatin receptor II.

American journal of translational research

Sun L, He Q, Tsai C, Lei J, Chen J, Vienna Makcey L, Coy DH.
PMID: 29511449
Am J Transl Res. 2018 Feb 15;10(2):545-553. eCollection 2018.

Small cell lung cancer (SCLC) is a malignant human cancer and patients have very limited benefit from traditional anticancer treatments, with a poor five-year survival rate being 10% less. In present study, we observed that Notch signalling activation induced...

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Sun L, He Q, Tsai C, et al. HDAC inhibitors suppressed small cell lung cancer cell growth and enhanced the suppressive effects of receptor-targeting cytotoxins via upregulating somatostatin receptor II. Am J Transl Res. 2018;10(2):545-553
Sun, L., He, Q., Tsai, C., Lei, J., Chen, J., Vienna Makcey, L., & Coy, D. H. (2018). HDAC inhibitors suppressed small cell lung cancer cell growth and enhanced the suppressive effects of receptor-targeting cytotoxins via upregulating somatostatin receptor II. American journal of translational research, 10(2), 545-553.
Sun, Lichun, et al. "HDAC inhibitors suppressed small cell lung cancer cell growth and enhanced the suppressive effects of receptor-targeting cytotoxins via upregulating somatostatin receptor II." American journal of translational research vol. 10,2 (2018): 545-553.
Sun L, He Q, Tsai C, Lei J, Chen J, Vienna Makcey L, Coy DH. HDAC inhibitors suppressed small cell lung cancer cell growth and enhanced the suppressive effects of receptor-targeting cytotoxins via upregulating somatostatin receptor II. Am J Transl Res. 2018 Feb 15;10(2):545-553. eCollection 2018. PMID: 29511449; PMCID: PMC5835820.
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Roles of cytochromes P450 in plant reproductive development.

The International journal of developmental biology

Distéfano AM, Setzes N, Cascallares M, Fiol DF, Zabaleta E, Pagnussat GC.
PMID: 32930346
Int J Dev Biol. 2021;65(4):187-194. doi: 10.1387/ijdb.200100gp.

The cytochrome P450 superfamily is a large enzymatic protein family that is widely distributed along diverse kingdoms. In plants, cytochrome P450 monooxygenases (CYPs) participate in a vast array of pathways leading to the synthesis and modification of multiple metabolites...

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Distéfano AM, Setzes N, Cascallares M, et al. Roles of cytochromes P450 in plant reproductive development. Int J Dev Biol. 2021;65(4):187-194doi: 10.1387/ijdb.200100gp.
Distéfano, A. M., Setzes, N., Cascallares, M., Fiol, D. F., Zabaleta, E., & Pagnussat, G. C. (2021). Roles of cytochromes P450 in plant reproductive development. The International journal of developmental biology, 65(4), 187-194. https://doi.org/10.1387/ijdb.200100gp
Distéfano, Ayelén M, et al. "Roles of cytochromes P450 in plant reproductive development." The International journal of developmental biology vol. 65,4 (2021): 187-194. doi: https://doi.org/10.1387/ijdb.200100gp
Distéfano AM, Setzes N, Cascallares M, Fiol DF, Zabaleta E, Pagnussat GC. Roles of cytochromes P450 in plant reproductive development. Int J Dev Biol. 2021;65(4):187-194. doi: 10.1387/ijdb.200100gp. PMID: 32930346.
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Periodic nonlinear sliding modes for two uniformly magnetized spheres.

Chaos (Woodbury, N.Y.)

Edwards BF, Edwards JM.
PMID: 28576112
Chaos. 2017 May;27(5):053107. doi: 10.1063/1.4982202.

A uniformly magnetized sphere slides without friction along the surface of a second, identical sphere that is held fixed in space, subject to the magnetic force and torque of the fixed sphere and the normal force. The free sphere...

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Edwards BF, Edwards JM. Periodic nonlinear sliding modes for two uniformly magnetized spheres. Chaos. 2017;27(5):053107doi: 10.1063/1.4982202.
Edwards, B. F., & Edwards, J. M. (2017). Periodic nonlinear sliding modes for two uniformly magnetized spheres. Chaos (Woodbury, N.Y.), 27(5), 053107. https://doi.org/10.1063/1.4982202
Edwards, Boyd F, and Edwards, John M. "Periodic nonlinear sliding modes for two uniformly magnetized spheres." Chaos (Woodbury, N.Y.) vol. 27,5 (2017): 053107. doi: https://doi.org/10.1063/1.4982202
Edwards BF, Edwards JM. Periodic nonlinear sliding modes for two uniformly magnetized spheres. Chaos. 2017 May;27(5):053107. doi: 10.1063/1.4982202. PMID: 28576112.
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Showing 25 to 36 of 180 entries