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G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment.

Journal for immunotherapy of cancer

Martinez Sanz P, van Rees DJ, van Zogchel LMJ, Klein B, Bouti P, Olsman H, Schornagel K, Kok I, Sunak A, Leeuwenburg K, Timmerman I, Dierselhuis MP, Kholosy WM, Molenaar JJ, van Bruggen R, van den Berg TK, Kuijpers TW, Matlung HL, Tytgat GAM, Franke K.
PMID: 34049929
J Immunother Cancer. 2021 May;9(5). doi: 10.1136/jitc-2020-002259.

BACKGROUND: Current immunotherapy for patients with high-risk neuroblastoma involves the therapeutic antibody dinutuximab that targets GD2, a ganglioside expressed on the majority of neuroblastoma tumors. Opsonized tumor cells are killed through antibody-dependent cellular cytotoxicity (ADCC), a process mediated by...

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Martinez Sanz P, van Rees DJ, van Zogchel LMJ, et al. G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment. J Immunother Cancer. 2021;9(5)doi: 10.1136/jitc-2020-002259.
Martinez Sanz, P., van Rees, D. J., van Zogchel, L. M. J., Klein, B., Bouti, P., Olsman, H., Schornagel, K., Kok, I., Sunak, A., Leeuwenburg, K., Timmerman, I., Dierselhuis, M. P., Kholosy, W. M., Molenaar, J. J., van Bruggen, R., van den Berg, T. K., Kuijpers, T. W., Matlung, H. L., Tytgat, G. A. M., & Franke, K. (2021). G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment. Journal for immunotherapy of cancer, 9(5), . https://doi.org/10.1136/jitc-2020-002259
Martinez Sanz, Paula, et al. "G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment." Journal for immunotherapy of cancer vol. 9,5 (2021). doi: https://doi.org/10.1136/jitc-2020-002259
Martinez Sanz P, van Rees DJ, van Zogchel LMJ, Klein B, Bouti P, Olsman H, Schornagel K, Kok I, Sunak A, Leeuwenburg K, Timmerman I, Dierselhuis MP, Kholosy WM, Molenaar JJ, van Bruggen R, van den Berg TK, Kuijpers TW, Matlung HL, Tytgat GAM, Franke K. G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment. J Immunother Cancer. 2021 May;9(5). doi: 10.1136/jitc-2020-002259. PMID: 34049929; PMCID: PMC8166600.
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Active single cell encapsulation using SAW overcoming the limitations of Poisson distribution.

Lab on a chip

Link A, McGrath JS, Zaimagaoglu M, Franke T.
PMID: 34889927
Lab Chip. 2021 Dec 21;22(1):193-200. doi: 10.1039/d1lc00880c.

We demonstrate the use of an acoustic device to actively encapsulate single red blood cells into individual droplets in a T-junction. We compare the active encapsulation with the passive encapsulation depending on the number of loaded cells as well...

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Link A, McGrath JS, Zaimagaoglu M, et al. Active single cell encapsulation using SAW overcoming the limitations of Poisson distribution. Lab Chip. 2021;22(1):193-200doi: 10.1039/d1lc00880c.
Link, A., McGrath, J. S., Zaimagaoglu, M., & Franke, T. (2021). Active single cell encapsulation using SAW overcoming the limitations of Poisson distribution. Lab on a chip, 22(1), 193-200. https://doi.org/10.1039/d1lc00880c
Link, Andreas, et al. "Active single cell encapsulation using SAW overcoming the limitations of Poisson distribution." Lab on a chip vol. 22,1 (2021): 193-200. doi: https://doi.org/10.1039/d1lc00880c
Link A, McGrath JS, Zaimagaoglu M, Franke T. Active single cell encapsulation using SAW overcoming the limitations of Poisson distribution. Lab Chip. 2021 Dec 21;22(1):193-200. doi: 10.1039/d1lc00880c. PMID: 34889927.
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High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling.

Stem cells translational medicine

Manstein F, Ullmann K, Kropp C, Halloin C, Triebert W, Franke A, Farr CM, Sahabian A, Haase A, Breitkreuz Y, Peitz M, Brüstle O, Kalies S, Martin U, Olmer R, Zweigerdt R.
PMID: 33660952
Stem Cells Transl Med. 2021 Jul;10(7):1063-1080. doi: 10.1002/sctm.20-0453. Epub 2021 Mar 04.

To harness the full potential of human pluripotent stem cells (hPSCs) we combined instrumented stirred tank bioreactor (STBR) technology with the power of in silico process modeling to overcome substantial, hPSC-specific hurdles toward their mass production. Perfused suspension culture...

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Manstein F, Ullmann K, Kropp C, et al. High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling. Stem Cells Transl Med. 2021;10(7):1063-1080doi: 10.1002/sctm.20-0453.
Manstein, F., Ullmann, K., Kropp, C., Halloin, C., Triebert, W., Franke, A., Farr, C. M., Sahabian, A., Haase, A., Breitkreuz, Y., Peitz, M., Brüstle, O., Kalies, S., Martin, U., Olmer, R., & Zweigerdt, R. (2021). High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling. Stem cells translational medicine, 10(7), 1063-1080. https://doi.org/10.1002/sctm.20-0453
Manstein, Felix, et al. "High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling." Stem cells translational medicine vol. 10,7 (2021): 1063-1080. doi: https://doi.org/10.1002/sctm.20-0453
Manstein F, Ullmann K, Kropp C, Halloin C, Triebert W, Franke A, Farr CM, Sahabian A, Haase A, Breitkreuz Y, Peitz M, Brüstle O, Kalies S, Martin U, Olmer R, Zweigerdt R. High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling. Stem Cells Transl Med. 2021 Jul;10(7):1063-1080. doi: 10.1002/sctm.20-0453. Epub 2021 Mar 04. PMID: 33660952; PMCID: PMC8235132.
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Phantom epistasis between unlinked loci.

Nature

Hemani G, Powell JE, Wang H, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Martin NG, Metspalu A, Franke L, Montgomery GW, Goddard ME, Gibson G, Yang J, Visscher PM.
PMID: 34381229
Nature. 2021 Aug;596(7871):E1-E3. doi: 10.1038/s41586-021-03765-z. Epub 2021 Aug 11.

No abstract available.

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Hemani G, Powell JE, Wang H, et al. Phantom epistasis between unlinked loci. Nature. 2021;596(7871):E1-E3doi: 10.1038/s41586-021-03765-z.
Hemani, G., Powell, J. E., Wang, H., Shakhbazov, K., Westra, H. J., Esko, T., Henders, A. K., McRae, A. F., Martin, N. G., Metspalu, A., Franke, L., Montgomery, G. W., Goddard, M. E., Gibson, G., Yang, J., & Visscher, P. M. (2021). Phantom epistasis between unlinked loci. Nature, 596(7871), E1-E3. https://doi.org/10.1038/s41586-021-03765-z
Hemani, Gibran, et al. "Phantom epistasis between unlinked loci." Nature vol. 596,7871 (2021): E1-E3. doi: https://doi.org/10.1038/s41586-021-03765-z
Hemani G, Powell JE, Wang H, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Martin NG, Metspalu A, Franke L, Montgomery GW, Goddard ME, Gibson G, Yang J, Visscher PM. Phantom epistasis between unlinked loci. Nature. 2021 Aug;596(7871):E1-E3. doi: 10.1038/s41586-021-03765-z. Epub 2021 Aug 11. PMID: 34381229.
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Showing 1429 to 1432 of 1432 entries