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Showing 229 to 236 of 236 entries
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Association of Apparent Treatment-Resistant Hypertension With Differential Risk of End-Stage Kidney Disease Across Racial Groups in the Million Veteran Program.

Hypertension (Dallas, Tex. : 1979)

Akwo EA, Robinson-Cohen C, Chung CP, Shah SC, Brown NJ, Ikizler TA, Wilson OD, Rowan BX, Shuey MM, Siew ED, Luther JM, Giri A, Hellwege JN, Velez Edwards DR, Roumie CL, Tao R, Tsao PS, Gaziano JM, Wilson PWF, O'Donnell CJ, Edwards TL, Kovesdy CP, Hung AM.
PMID: 34148359
Hypertension. 2021 Aug;78(2):376-386. doi: 10.1161/HYPERTENSIONAHA.120.16181. Epub 2021 Jun 21.

[Figure: see text].

Functional and Radiological Improvement in a COVID-19 Pneumonia Patient Treated With Steroids.

Cureus

Singh R, Gaziano D.
PMID: 34188995
Cureus. 2021 May 26;13(5):e15257. doi: 10.7759/cureus.15257.

Like its predecessors, coronavirus disease 2019 (COVID-19) can lead to long-term health-related consequences in a significant segment of the afflicted population. Although the medical community has developed multiple vaccines by now, COVID-19 has affected over 100 million individuals worldwide...

Trajectories of Frailty in the 5 Years Prior to Death Among U.S. Veterans Born 1927-1934.

The journals of gerontology. Series A, Biological sciences and medical sciences

Ward RE, Orkaby AR, Dumontier C, Charest B, Hawley CE, Yaksic E, Quach L, Kim DH, Gagnon DR, Gaziano JM, Cho K, Djousse L, Driver JA.
PMID: 34244759
J Gerontol A Biol Sci Med Sci. 2021 Oct 13;76(11):e347-e353. doi: 10.1093/gerona/glab196.

BACKGROUND: Electronic frailty indices (eFIs) are increasingly used to identify patients at risk for morbidity and mortality. Whether eFIs capture the spectrum of frailty change, including decline, stability, and improvement, is unknown.METHODS: In a nationwide retrospective birth cohort of...

Risk factors and prediction models for incident heart failure with reduced and preserved ejection fraction.

ESC heart failure

Gaziano L, Cho K, Djousse L, Schubert P, Galloway A, Ho YL, Kurgansky K, Gagnon DR, Russo JP, Di Angelantonio E, Wood AM, Danesh J, Gaziano JM, Butterworth AS, Wilson PWF, Joseph J.
PMID: 34528757
ESC Heart Fail. 2021 Dec;8(6):4893-4903. doi: 10.1002/ehf2.13429. Epub 2021 Sep 16.

AIMS: This study aims to develop the first race-specific and sex-specific risk prediction models for heart failure with preserved (HFpEF) and reduced ejection fraction (HFrEF).METHODS AND RESULTS: We created a cohort of 1.8 million individuals who had an outpatient...

Evaluation of the Usage and Dosing of Guideline-Directed Medical Therapy for Heart Failure With Reduced Ejection Fraction Patients in Clinical Practice.

Journal of pharmacy practice

Smith KV, Dunning JR, Fischer CM, MacLean TE, Bosque-Hamilton JW, Fera LE, Grant JY, Zelle DJ, Matta L, Gaziano TA, MacRae CA, Scirica BM, Desai AS.
PMID: 33813934
J Pharm Pract. 2021 Apr 05;8971900211004840. doi: 10.1177/08971900211004840. Epub 2021 Apr 05.

BACKGROUND: Although strategies for optimization of pharmacologic therapy in patients with heart failure with reduced ejection fraction (HFrEF) are scripted by guidelines, data from HF registries suggests that guideline-directed medical therapies (GDMT) are underutilized among eligible patients. Whether this...

Comparative Effectiveness of BNT162b2 and mRNA-1273 Vaccines in U.S. Veterans.

The New England journal of medicine

Dickerman BA, Gerlovin H, Madenci AL, Kurgansky KE, Ferolito BR, Figueroa Muñiz MJ, Gagnon DR, Gaziano JM, Cho K, Casas JP, Hernán MA.
PMID: 34942066
N Engl J Med. 2022 Jan 13;386(2):105-115. doi: 10.1056/NEJMoa2115463. Epub 2021 Dec 01.

BACKGROUND: The messenger RNA (mRNA)-based vaccines BNT162b2 and mRNA-1273 are more than 90% effective against coronavirus disease 2019 (Covid-19). However, their comparative effectiveness for a range of outcomes across diverse populations is unknown.METHODS: We emulated a target trial using...

Population health management of low-density lipoprotein cholesterol via a remote, algorithmic, navigator-executed program.

American heart journal

Plutzky J, Benson MD, Chaney K, Bui TV, Kraft M, Matta L, McPartlin M, Zelle D, Cannon CP, Dodek A, Gaziano TA, Desai AS, MacRae CA, Scirica BM.
PMID: 34481756
Am Heart J. 2022 Jan;243:15-27. doi: 10.1016/j.ahj.2021.08.017. Epub 2021 Sep 03.

BACKGROUND: Implementation of guideline-directed cholesterol management remains low despite definitive evidence establishing such measures reduce cardiovascular (CV) events, especially in high atherosclerotic CV disease (ASCVD) risk patients. Modern electronic resources now exist that may help improve health care delivery....

Rapid establishment of a frontline field laboratory in response to an imported outbreak of Ebola virus disease in western Uganda, June 2019.

PLoS neglected tropical diseases

Schuh AJ, Kyondo J, Graziano J, Balinandi S, Kainulainen MH, Tumusiime A, Nyakarahuka L, Mulei S, Baluku J, Lonergan W, Mayer O, Masereka R, Masereka F, Businge E, Gatare A, Kabyanga L, Muhindo S, Mugabe R, Makumbi I, Kayiwa J, Wetaka MM, Brown V, Ojwang J, Nelson L, Millard M, Nichol ST, Montgomery JM, Taboy CH, Lutwama JJ, Klena JD.
PMID: 34860831
PLoS Negl Trop Dis. 2021 Dec 03;15(12):e0009967. doi: 10.1371/journal.pntd.0009967. eCollection 2021 Dec.

The Democratic Republic of the Congo (DRC) declared an Ebola virus disease (EVD) outbreak in North Kivu in August 2018. By June 2019, the outbreak had spread to 26 health zones in northeastern DRC, causing >2,000 reported cases and...

Showing 229 to 236 of 236 entries