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Showing 25 to 36 of 247 entries
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A Review on the Role of AFAP1-AS1 in the Pathoetiology of Cancer.

Frontiers in oncology

Ghafouri-Fard S, Khoshbakht T, Hussen BM, Taheri M, Mokhtari M.
PMID: 34912717
Front Oncol. 2021 Nov 29;11:777849. doi: 10.3389/fonc.2021.777849. eCollection 2021.

AFAP1-AS1 is a long non-coding RNA which partakes in the pathoetiology of several cancers. The sense protein coding gene from this locus partakes in the regulation of cytophagy, cell motility, invasive characteristics of cells and metastatic ability. In addition...

Perspectives on the Role of Non-Coding RNAs in the Regulation of Expression and Function of the Estrogen Receptor.

Cancers

Taheri M, Shoorei H, Dinger ME, Ghafouri-Fard S.
PMID: 32759784
Cancers (Basel). 2020 Aug 04;12(8). doi: 10.3390/cancers12082162.

Estrogen receptors (ERs) comprise several nuclear and membrane-bound receptors with different tissue-specific functions. ERα and ERβ are two nuclear members of this family, whereas G protein-coupled estrogen receptor (GPER), ER-X, and Gq-coupled membrane estrogen receptor (Gq-mER) are membrane-bound G...

The Role of Long Non-coding RNAs in Cancer Metabolism: A Concise Review.

Frontiers in oncology

Ghafouri-Fard S, Shoorei H, Taheri M.
PMID: 33123468
Front Oncol. 2020 Oct 06;10:555825. doi: 10.3389/fonc.2020.555825. eCollection 2020.

Dysregulation of metabolic pathways in cancer cells is regarded as a hallmark of cancer. Identification of these abnormalities in cancer cells dates back to more than six decades, far before discovery of oncogenes and tumor suppressor genes. Based on...

Signaling pathways modulated by miRNAs in breast cancer angiogenesis and new therapeutics.

Pathology, research and practice

Hussen BM, Salihi A, Abdullah ST, Rasul MF, Hidayat HJ, Hajiesmaeili M, Ghafouri-Fard S.
PMID: 35032831
Pathol Res Pract. 2022 Jan 10;230:153764. doi: 10.1016/j.prp.2022.153764. Epub 2022 Jan 10.

MicroRNAs (miRNAs) act as oncogenes or tumor suppressors by suppressing the expression of target genes, some of which are engaged in angiogenic signaling pathways directly or indirectly. Tumor development and metastasis are dependent on angiogenesis, and it is the...

The emerging roles of NGS in clinical oncology and personalized medicine.

Pathology, research and practice

Hussen BM, Abdullah ST, Salihi A, Sabir DK, Sidiq KR, Rasul MF, Hidayat HJ, Ghafouri-Fard S, Taheri M, Jamali E.
PMID: 35033746
Pathol Res Pract. 2022 Jan 10;230:153760. doi: 10.1016/j.prp.2022.153760. Epub 2022 Jan 10.

Next-generation sequencing (NGS) has been increasingly popular in genomics studies over the last decade, as new sequencing technology has been created and improved. Recently, NGS started to be used in clinical oncology to improve cancer therapy through diverse modalities...

Abnormal expression of NF-κB-related transcripts in blood of patients with inflammatory peripheral nerve disorders.

Metabolic brain disease

Azimi T, Ghafouri-Fard S, Badrlou E, Omrani MD, Nazer N, Sayad A, Taheri M.
PMID: 34410580
Metab Brain Dis. 2021 Dec;36(8):2369-2376. doi: 10.1007/s11011-021-00778-5. Epub 2021 Aug 19.

The NF-κB family includes some transcription factors which have important functions in the regulation of immune responses, therefore participating in the pathophysiology of inflammatory conditions such as peripheral neuropathies. We have quantified expression of a number of NF-κB-related transcripts...

LncRNA signature in colorectal cancer.

Pathology, research and practice

Ghafouri-Fard S, Hussen BM, Gharebaghi A, Eghtedarian R, Taheri M.
PMID: 33857856
Pathol Res Pract. 2021 Jun;222:153432. doi: 10.1016/j.prp.2021.153432. Epub 2021 Apr 07.

Colorectal cancer (CRC) is among the most frequent cancers and is associated with high mortality particularly when being diagnosed in advanced stages. Although several environmental and intrinsic risk factors have been identified, the underlying cause of CRC is not...

The lncRNA .

Non-coding RNA research

Gholami L, Ghafouri-Fard S, Mirzajani S, Arsang-Jang S, Taheri M, Dehbani Z, Dehghani S, Houshmand B, Amid R, Sayad A, Shams B.
PMID: 32346660
Noncoding RNA Res. 2020 Apr 17;5(2):60-66. doi: 10.1016/j.ncrna.2020.04.001. eCollection 2020 Jun.

Long non-coding RNAs (lncRNAs) have crucial roles in lncRNAs in periodontal development and disorders of this tissue. A number of lncRNAs especially those regulating immune responses contribute in the pathophysiology of periodontitis. In the current case-control study, we assessed...

Long Non-coding RNA RMRP in the Pathogenesis of Human Disorders.

Frontiers in cell and developmental biology

Hussen BM, Azimi T, Hidayat HJ, Taheri M, Ghafouri-Fard S.
PMID: 33996836
Front Cell Dev Biol. 2021 Apr 30;9:676588. doi: 10.3389/fcell.2021.676588. eCollection 2021.

RNA component of mitochondrial RNA processing endoribonuclease (RMRP) is a non-coding transcript firstly acknowledged for its association with the cartilage-hair hypoplasia (CHH) syndrome, a rare autosomal recessive condition. This transcript has been spotted in both nucleus and mitochondria. In...

Assessment of ACE1 variants and ACE1/ACE2 expression in COVID-19 patients.

Vascular pharmacology

Akbari M, Taheri M, Mehrpoor G, Eslami S, Hussen BM, Ghafouri-Fard S, Arefian N.
PMID: 34774774
Vascul Pharmacol. 2021 Nov 10;142:106934. doi: 10.1016/j.vph.2021.106934. Epub 2021 Nov 10.

Contribution of the renin-angiotensinogen system in the risk of COVID-19 and related complications have been assessed by several groups. However, the results are not consistent. We examined levels of ACE1 and ACE2 in the circulation of two groups of...

Stress Granules Involved in Formation, Progression and Metastasis of Cancer: A Scoping Review.

Frontiers in cell and developmental biology

Asadi MR, Rahmanpour D, Moslehian MS, Sabaie H, Hassani M, Ghafouri-Fard S, Taheri M, Rezazadeh M.
PMID: 34604242
Front Cell Dev Biol. 2021 Sep 17;9:745394. doi: 10.3389/fcell.2021.745394. eCollection 2021.

The assembly of stress granules (SGs) is a well-known cellular strategy for reducing stress-related damage and promoting cell survival. SGs have become important players in human health, in addition to their fundamental role in the stress response. The critical...

A Review on the Role of AFAP1-AS1 in the Pathoetiology of Cancer.

Frontiers in oncology

Ghafouri-Fard S, Khoshbakht T, Hussen BM, Taheri M, Mokhtari M.
PMID: 34912717
Front Oncol. 2021 Nov 29;11:777849. doi: 10.3389/fonc.2021.777849. eCollection 2021.

AFAP1-AS1 is a long non-coding RNA which partakes in the pathoetiology of several cancers. The sense protein coding gene from this locus partakes in the regulation of cytophagy, cell motility, invasive characteristics of cells and metastatic ability. In addition...

Showing 25 to 36 of 247 entries