Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 181 to 189 of 189 entries
Sorted by: Best Match Show Resources per page
Probing the mechanisms of two exonuclease domain mutators of DNA polymerase ϵ.

Nucleic acids research

Dahl JM, Thomas N, Tracy MA, Hearn BL, Perera L, Kennedy SR, Herr AJ, Kunkel TA.
PMID: 35037018
Nucleic Acids Res. 2022 Jan 17; doi: 10.1093/nar/gkab1255. Epub 2022 Jan 17.

We report the properties of two mutations in the exonuclease domain of the Saccharomyces cerevisiae DNA polymerase ϵ. One, pol2-Y473F, increases the mutation rate by about 20-fold, similar to the catalytically dead pol2-D290A/E290A mutant. The other, pol2-N378K, is a...

Preoperative hematocrit and platelet count are associated with blood loss during spinal fusion for children with neuromuscular scoliosis.

Journal of perioperative practice

Lewen MO, Berry J, Johnson C, Grace R, Glader L, Crofton C, Leahy I, Pallikonda N, Litvinova A, Staffa SJ, Glotzbecker M, Emans J, Hresko MT, Ellen M, Troy M, Singer SJ, Ferrari L.
PMID: 33826437
J Perioper Pract. 2021 Apr 07;1750458920962634. doi: 10.1177/1750458920962634. Epub 2021 Apr 07.

AIM: To assess the relationship of preoperative hematology laboratory results with intraoperative estimated blood loss and transfusion volumes during posterior spinal fusion for pediatric neuromuscular scoliosis.METHODS: Retrospective chart review of 179 children with neuromuscular scoliosis undergoing spinal fusion at...

Factors Affecting Incidence Rate of Exertional Heat Illnesses: Analysis of 6 Years of High School Football Practices in North Central Florida.

Orthopaedic journal of sports medicine

Tripp BL, Winkelmann ZK, Eberman LE, Smith MS.
PMID: 34568503
Orthop J Sports Med. 2021 Sep 22;9(9):23259671211026627. doi: 10.1177/23259671211026627. eCollection 2021 Sep.

BACKGROUND: Although experts have advocated for regionally specific heat safety guidelines for decades, guidelines have not been universally adopted.PURPOSE: To describe the rate and risk factors associated with exertional heat illness (EHI).STUDY DESIGN: Descriptive epidemiology study.METHODS: For a 3-month...

The compressive, shear, biochemical, and histological characteristics of diabetic and non-diabetic plantar skin are minimally different.

Journal of biomechanics

Brady L, Pai S, Iaquinto JM, Wang YN, Ledoux WR.
PMID: 34688066
J Biomech. 2021 Dec 02;129:110797. doi: 10.1016/j.jbiomech.2021.110797. Epub 2021 Oct 07.

Diabetes is associated with lower limb co-morbidities, including ulceration and subsequent amputation. As a systemic disease, diabetes affects the microstructure of soft tissues, and material microstructural changes are known to affect the macroscale mechanics. However, the associations between diabetes-related...

The compressive, shear, biochemical, and histological characteristics of diabetic and non-diabetic plantar skin are minimally different.

Journal of biomechanics

Brady L, Pai S, Iaquinto JM, Wang YN, Ledoux WR.
PMID: 34688066
J Biomech. 2021 Dec 02;129:110797. doi: 10.1016/j.jbiomech.2021.110797. Epub 2021 Oct 07.

Diabetes is associated with lower limb co-morbidities, including ulceration and subsequent amputation. As a systemic disease, diabetes affects the microstructure of soft tissues, and material microstructural changes are known to affect the macroscale mechanics. However, the associations between diabetes-related...

The Families and Schools for Health Project: A Longitudinal Cluster Randomized Controlled Trial Targeting Children with Overweight and Obesity.

International journal of environmental research and public health

Topham GL, Washburn IJ, Hubbs-Tait L, Kennedy TS, Rutledge JM, Page MC, Swindle T, Shriver LH, Harrist AW.
PMID: 34444492
Int J Environ Res Public Health. 2021 Aug 19;18(16). doi: 10.3390/ijerph18168744.

This cluster randomized controlled trial aimed at overweight and obese children compared three treatments. Two psychoeducation interventions for parents and children were conducted: Family Lifestyle (FL) focused on food and physical activity; Family Dynamics (FD) added parenting and healthy...

The Role of Glomerular Epithelial Injury in Kidney Function Decline in Patients With Diabetic Kidney Disease in the TRIDENT Cohort.

Kidney international reports

Palmer MB, Abedini A, Jackson C, Blady S, Chatterjee S, Sullivan KM, Townsend RR, Brodbeck J, Almaani S, Srivastava A, Avasare R, Ross MJ, Mottl AK, Argyropoulos C, Hogan J, Susztak K.
PMID: 33912757
Kidney Int Rep. 2021 Feb 03;6(4):1066-1080. doi: 10.1016/j.ekir.2021.01.025. eCollection 2021 Apr.

INTRODUCTION: Although diabetic kidney disease (DKD) is responsible for more than half of all chronic and end-stage kidney disease (ESKD), the association of light (LM) and electron microscopic (EM) structural changes with clinical parameters and prognosis in DKD is...

Induced point mutations in the phytoene synthase 1 gene cause differences in carotenoid content during tomato fruit ripening.

Molecular breeding : new strategies in plant improvement

Gady AL, Vriezen WH, Van de Wal MH, Huang P, Bovy AG, Visser RG, Bachem CW.
PMID: 22408384
Mol Breed. 2012 Mar;29(3):801-812. doi: 10.1007/s11032-011-9591-9. Epub 2011 Jun 12.

In tomato, carotenoids are important with regard to major breeding traits such as fruit colour and human health. The enzyme phytoene synthase (PSY1) directs metabolic flux towards carotenoid synthesis. Through TILLING (Targeting Induced Local Lesions IN Genomes), we have...

Using systemic interventions to reduce intimate partner violence or child maltreatment: A systematic review of publications between 2010 and 2019.

Journal of marital and family therapy

Stith SM, Topham GL, Spencer C, Jones B, Coburn K, Kelly L, Langston Z.
PMID: 34697816
J Marital Fam Ther. 2022 Jan;48(1):231-250. doi: 10.1111/jmft.12566. Epub 2021 Oct 26.

This systematic review seeks to understand the effectiveness of systemic interventions to reduce Intimate Partner Violence (IPV) or child maltreatment published between January 2010 and December 2019. We found nine studies reviewing systemic interventions for IPV and 12 studies...

Showing 181 to 189 of 189 entries