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Showing 181 to 192 of 192 entries
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Tonal Emergence: An agent-based model of tonal coordination.

Cognition

Setzler MD, Goldstone RL.
PMID: 34952223
Cognition. 2021 Dec 21;221:104968. doi: 10.1016/j.cognition.2021.104968. Epub 2021 Dec 21.

Humans have a remarkable capacity for coordination. Our ability to interact and act jointly in groups is crucial to our success as a species. Joint Action (JA) research has often concerned itself with simplistic behaviors in highly constrained laboratory...

Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts.

Gastroenterology

Bortolomeazzi M, Keddar MR, Montorsi L, Acha-Sagredo A, Benedetti L, Temelkovski D, Choi S, Petrov N, Todd K, Wai P, Kohl J, Denner T, Nye E, Goldstone R, Ward S, Wilson GA, Al Bakir M, Swanton C, John S, Miles J, Larijani B, Kunene V, Fontana E, Arkenau HT, Parker PJ, Rodriguez-Justo M, Shiu KK, Spencer J, Ciccarelli FD.
PMID: 34197832
Gastroenterology. 2021 Oct;161(4):1179-1193. doi: 10.1053/j.gastro.2021.06.064. Epub 2021 Jun 29.

BACKGROUND & AIMS: Colorectal cancer (CRC) shows variable response to immune checkpoint blockade, which can only partially be explained by high tumor mutational burden (TMB). We conducted an integrated study of the cancer tissue and associated tumor microenvironment (TME)...

Addressing diversity and complexity in the community engagement literature: The rationale for a realist review.

Wellcome open research

Richardson EZL, Bandewar SVS, Boulanger RF, Mehta R, Lin T, Vincent R, Molyneux S, Goldstone A, Lavery JV.
PMID: 34632082
Wellcome Open Res. 2020 Jan 07;5:1. doi: 10.12688/wellcomeopenres.15525.1. eCollection 2020.

In this research note we reflect on our failed attempt to synthesize the community engagement literature through a standard systematic review and explain our rationale for now embarking on a realist synthesis of community engagement in global health research....

Probing the Paradigm of Promiscuity for N-Heterocyclic Carbene Complexes and their Protein Adduct Formation.

Angewandte Chemie (International ed. in English)

Sullivan MP, Cziferszky M, Tolbatov I, Truong D, Mercadante D, Re N, Gust R, Goldstone DC, Hartinger CG.
PMID: 34196088
Angew Chem Int Ed Engl. 2021 Sep 01;60(36):19928-19932. doi: 10.1002/anie.202106906. Epub 2021 Jul 28.

Metal complexes can be considered a "paradigm of promiscuity" when it comes to their interactions with proteins. They often form adducts with a variety of donor atoms in an unselective manner. We have characterized the adducts formed between a...

Valve-sparing reoperations for failed pulmonary autografts.

JTCVS techniques

Goldstone AB, Woo YJ.
PMID: 34977766
JTCVS Tech. 2021 Feb 12;10:408-412. doi: 10.1016/j.xjtc.2021.01.041. eCollection 2021 Dec.

No abstract available.

Efficacy, immunogenicity, and safety of a quadrivalent HPV vaccine in men: results of an open-label, long-term extension of a randomised, placebo-controlled, phase 3 trial.

The Lancet. Infectious diseases

Goldstone SE, Giuliano AR, Palefsky JM, Lazcano-Ponce E, Penny ME, Cabello RE, Moreira ED, Baraldi E, Jessen H, Ferenczy A, Kurman R, Ronnett BM, Stoler MH, Bautista O, Das R, Group T, Luxembourg A, Zhou HJ, Saah A.
PMID: 34780705
Lancet Infect Dis. 2021 Nov 12; doi: 10.1016/S1473-3099(21)00327-3. Epub 2021 Nov 12.

BACKGROUND: The quadrivalent human papillomavirus (HPV) vaccine was shown to prevent infections and lesions related to HPV6, 11, 16, and 18 in a randomised, placebo-controlled study in men aged 16-26 years. We assessed the incidences of external genital warts...

Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish.

Communications biology

Brun NR, Panlilio JM, Zhang K, Zhao Y, Ivashkin E, Stegeman JJ, Goldstone JV.
PMID: 34561524
Commun Biol. 2021 Sep 24;4(1):1129. doi: 10.1038/s42003-021-02626-9.

The most abundant polychlorinated biphenyl (PCB) congeners found in the environment and in humans are neurotoxic. This is of particular concern for early life stages because the exposure of the more vulnerable developing nervous system to neurotoxic chemicals can...

Trauma-informed care for youth suicide prevention: A qualitative analysis of caregivers' perspectives.

Psychological trauma : theory, research, practice and policy

Inscoe AB, Donisch K, Cheek S, Stokes C, Goldston DB, Asarnow JR.
PMID: 34166044
Psychol Trauma. 2021 Jun 24; doi: 10.1037/tra0001054. Epub 2021 Jun 24.

OBJECTIVE: Research shows elevated rates of trauma exposure and traumatic stress among youth with suicidal thoughts and behaviors, underscoring the need for a trauma-informed approach to suicide prevention and intervention. The purpose of this study was to identify, from...

Risk for depression tripled during the COVID-19 pandemic in emerging adults followed for the last 8 years.

Psychological medicine

Alzueta E, Podhajsky S, Zhao Q, Tapert SF, Thompson WK, de Zambotti M, Yuksel D, Kiss O, Wang R, Volpe L, Prouty D, Colrain IM, Clark DB, Goldston DB, Nooner KB, De Bellis MD, Brown SA, Nagel BJ, Pfefferbaum A, Sullivan EV, Baker FC, Pohl KM.
PMID: 34726149
Psychol Med. 2021 Nov 02;1-8. doi: 10.1017/S0033291721004062. Epub 2021 Nov 02.

BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has significantly increased depression rates, particularly in emerging adults. The aim of this study was to examine longitudinal changes in depression risk before and during COVID-19 in a cohort of emerging adults...

Pioneers in Vascular Surgery: F. William Blaisdell.

Journal of vascular surgery

Goldstone J.
PMID: 34688400
J Vasc Surg. 2021 Nov;74(5):1763-1764. doi: 10.1016/j.jvs.2021.03.026.

No abstract available.

Hyponatremia in Children and Adults with Prader-Willi Syndrome: A Survey Involving Seven Countries.

Journal of clinical medicine

Coupaye M, Pellikaan K, Goldstone AP, Crinò A, Grugni G, Markovic TP, Høybye C, Caixàs A, Mosbah H, De Graaff LCG, Tauber M, Poitou C.
PMID: 34441851
J Clin Med. 2021 Aug 12;10(16). doi: 10.3390/jcm10163555.

In Prader-Willi syndrome (PWS), conditions that are associated with hyponatremia are common, such as excessive fluid intake (EFI), desmopressin use and syndrome of inappropriate antidiuretic hormone (SIADH) caused by psychotropic medication. However, the prevalence of hyponatremia in PWS has...

Orphan cytochrome P450 20a1 CRISPR/Cas9 mutants and neurobehavioral phenotypes in zebrafish.

Scientific reports

Brun NR, Salanga MC, Mora-Zamorano FX, Lamb DC, Goldstone JV, Stegeman JJ.
PMID: 34903767
Sci Rep. 2021 Dec 13;11(1):23892. doi: 10.1038/s41598-021-03068-3.

Orphan cytochrome P450 (CYP) enzymes are those for which biological substrates and function(s) are unknown. Cytochrome P450 20A1 (CYP20A1) is the last human orphan P450 enzyme, and orthologs occur as single genes in every vertebrate genome sequenced to date....

Showing 181 to 192 of 192 entries