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Neural network activation similarity: a new measure to assist decision making in chemical toxicology.

Chemical science

Allen TEH, Wedlake AJ, Gelžinytė E, Gong C, Goodman JM, Gutsell S, Russell PJ.
PMID: 34123016
Chem Sci. 2020 Jun 24;11(28):7335-7348. doi: 10.1039/d0sc01637c.

Deep learning neural networks, constructed for the prediction of chemical binding at 79 pharmacologically important human biological targets, show extremely high performance on test data (accuracy 92.2 ± 4.2%, MCC 0.814 ± 0.093 and ROC-AUC 0.96 ± 0.04). A...

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Allen TEH, Wedlake AJ, Gelžinytė E, et al. Neural network activation similarity: a new measure to assist decision making in chemical toxicology. Chem Sci. 2020;11(28):7335-7348doi: 10.1039/d0sc01637c.
Allen, T. E. H., Wedlake, A. J., Gelžinytė, E., Gong, C., Goodman, J. M., Gutsell, S., & Russell, P. J. (2020). Neural network activation similarity: a new measure to assist decision making in chemical toxicology. Chemical science, 11(28), 7335-7348. https://doi.org/10.1039/d0sc01637c
Allen, Timothy E H, et al. "Neural network activation similarity: a new measure to assist decision making in chemical toxicology." Chemical science vol. 11,28 (2020): 7335-7348. doi: https://doi.org/10.1039/d0sc01637c
Allen TEH, Wedlake AJ, Gelžinytė E, Gong C, Goodman JM, Gutsell S, Russell PJ. Neural network activation similarity: a new measure to assist decision making in chemical toxicology. Chem Sci. 2020 Jun 24;11(28):7335-7348. doi: 10.1039/d0sc01637c. PMID: 34123016; PMCID: PMC8159362.
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A Novel Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Biomarker-Anti-DSG2-Is Absent in Athletes With Right Ventricular Enlargement.

CJC open

Dorian D, Chatterjee D, Connelly KA, Goodman JM, Yan AT, Bentley RF, Banks L, Hamilton RM, Dorian P.
PMID: 34993452
CJC Open. 2021 Jul 14;3(12):1413-1418. doi: 10.1016/j.cjco.2021.07.002. eCollection 2021 Dec.

BACKGROUND: Right ventricular (RV) enlargement is common in endurance athletes. It is usually considered to be physiological, but it is possible that this remodelling is adverse, manifesting as a variant of arrhythmogenic right ventricular cardiomyopathy (ARVC), termed "exercise-induced ARVC."...

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Dorian D, Chatterjee D, Connelly KA, et al. A Novel Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Biomarker-Anti-DSG2-Is Absent in Athletes With Right Ventricular Enlargement. CJC Open. 2021;3(12):1413-1418doi: 10.1016/j.cjco.2021.07.002.
Dorian, D., Chatterjee, D., Connelly, K. A., Goodman, J. M., Yan, A. T., Bentley, R. F., Banks, L., Hamilton, R. M., & Dorian, P. (2021). A Novel Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Biomarker-Anti-DSG2-Is Absent in Athletes With Right Ventricular Enlargement. CJC open, 3(12), 1413-1418. https://doi.org/10.1016/j.cjco.2021.07.002
Dorian, David, et al. "A Novel Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Biomarker-Anti-DSG2-Is Absent in Athletes With Right Ventricular Enlargement." CJC open vol. 3,12 (2021): 1413-1418. doi: https://doi.org/10.1016/j.cjco.2021.07.002
Dorian D, Chatterjee D, Connelly KA, Goodman JM, Yan AT, Bentley RF, Banks L, Hamilton RM, Dorian P. A Novel Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Biomarker-Anti-DSG2-Is Absent in Athletes With Right Ventricular Enlargement. CJC Open. 2021 Jul 14;3(12):1413-1418. doi: 10.1016/j.cjco.2021.07.002. eCollection 2021 Dec. PMID: 34993452; PMCID: PMC8712542.
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VRAI-selectivity: calculation of selectivity beyond transition state theory.

Organic & biomolecular chemistry

Lee S, Goodman JM.
PMID: 33949564
Org Biomol Chem. 2021 May 05;19(17):3940-3947. doi: 10.1039/d1ob00234a.

In recent years, a growing number of organic reactions in the literature have shown selectivity controlled by reaction dynamics rather than by transition state theory. Such reactions are difficult to analyse because the transition state theory approach often does...

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Lee S, Goodman JM. VRAI-selectivity: calculation of selectivity beyond transition state theory. Org Biomol Chem. 2021;19(17):3940-3947doi: 10.1039/d1ob00234a.
Lee, S., & Goodman, J. M. (2021). VRAI-selectivity: calculation of selectivity beyond transition state theory. Organic & biomolecular chemistry, 19(17), 3940-3947. https://doi.org/10.1039/d1ob00234a
Lee, Sanha, and Goodman, Jonathan M. "VRAI-selectivity: calculation of selectivity beyond transition state theory." Organic & biomolecular chemistry vol. 19,17 (2021): 3940-3947. doi: https://doi.org/10.1039/d1ob00234a
Lee S, Goodman JM. VRAI-selectivity: calculation of selectivity beyond transition state theory. Org Biomol Chem. 2021 May 05;19(17):3940-3947. doi: 10.1039/d1ob00234a. PMID: 33949564.
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Optimizing the workforce: a proposal to improve regionalization of care and emergency preparedness by broader integration of pediatric emergency physicians certified by the American Board of Pediatrics.

Journal of the American College of Emergency Physicians open

Woolridge D, Homme JJ, Amato CS, Pauze D, Rose E, Valente J, Ishimine P, Friesen P, Baldwin S, Joseph M, Saidinejad M, Perina D, Goodloe JM.
PMID: 33392559
J Am Coll Emerg Physicians Open. 2020 Jul 08;1(6):1520-1526. doi: 10.1002/emp2.12114. eCollection 2020 Dec.

BACKGROUND: Emergency care in the United States faces notable challenges with regard to children. In some jurisdictions, available resources are not sufficient to meet local needs. Physicians with specialty training in pediatric emergency care are largely concentrated in children's...

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Woolridge D, Homme JJ, Amato CS, et al. Optimizing the workforce: a proposal to improve regionalization of care and emergency preparedness by broader integration of pediatric emergency physicians certified by the American Board of Pediatrics. J Am Coll Emerg Physicians Open. 2020;1(6):1520-1526doi: 10.1002/emp2.12114.
Woolridge, D., Homme, J. J., Amato, C. S., Pauze, D., Rose, E., Valente, J., Ishimine, P., Friesen, P., Baldwin, S., Joseph, M., Saidinejad, M., Perina, D., & Goodloe, J. M. (2020). Optimizing the workforce: a proposal to improve regionalization of care and emergency preparedness by broader integration of pediatric emergency physicians certified by the American Board of Pediatrics. Journal of the American College of Emergency Physicians open, 1(6), 1520-1526. https://doi.org/10.1002/emp2.12114
Woolridge, Dale, et al. "Optimizing the workforce: a proposal to improve regionalization of care and emergency preparedness by broader integration of pediatric emergency physicians certified by the American Board of Pediatrics." Journal of the American College of Emergency Physicians open vol. 1,6 (2020): 1520-1526. doi: https://doi.org/10.1002/emp2.12114
Woolridge D, Homme JJ, Amato CS, Pauze D, Rose E, Valente J, Ishimine P, Friesen P, Baldwin S, Joseph M, Saidinejad M, Perina D, Goodloe JM. Optimizing the workforce: a proposal to improve regionalization of care and emergency preparedness by broader integration of pediatric emergency physicians certified by the American Board of Pediatrics. J Am Coll Emerg Physicians Open. 2020 Jul 08;1(6):1520-1526. doi: 10.1002/emp2.12114. eCollection 2020 Dec. PMID: 33392559; PMCID: PMC7771807.
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Measles in the 21st Century: Progress Toward Achieving and Sustaining Elimination.

The Journal of infectious diseases

Gastañaduy PA, Goodson JL, Panagiotakopoulos L, Rota PA, Orenstein WA, Patel M.
PMID: 34590128
J Infect Dis. 2021 Sep 30;224(12):S420-S428. doi: 10.1093/infdis/jiaa793.

The global measles vaccination program has been extraordinarily successful in reducing measles-related disease and deaths worldwide. Eradication of measles is feasible because of several key attributes, including humans as the only reservoir for the virus, broad access to diagnostic...

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Gastañaduy PA, Goodson JL, Panagiotakopoulos L, et al. Measles in the 21st Century: Progress Toward Achieving and Sustaining Elimination. J Infect Dis. 2021;224(12):S420-S428doi: 10.1093/infdis/jiaa793.
Gastañaduy, P. A., Goodson, J. L., Panagiotakopoulos, L., Rota, P. A., Orenstein, W. A., & Patel, M. (2021). Measles in the 21st Century: Progress Toward Achieving and Sustaining Elimination. The Journal of infectious diseases, 224(12), S420-S428. https://doi.org/10.1093/infdis/jiaa793
Gastañaduy, Paul A, et al. "Measles in the 21st Century: Progress Toward Achieving and Sustaining Elimination." The Journal of infectious diseases vol. 224,12 (2021): S420-S428. doi: https://doi.org/10.1093/infdis/jiaa793
Gastañaduy PA, Goodson JL, Panagiotakopoulos L, Rota PA, Orenstein WA, Patel M. Measles in the 21st Century: Progress Toward Achieving and Sustaining Elimination. J Infect Dis. 2021 Sep 30;224(12):S420-S428. doi: 10.1093/infdis/jiaa793. PMID: 34590128; PMCID: PMC8482021.
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Amino acid primed mTOR activity is essential for heart regeneration.

iScience

Miklas JW, Levy S, Hofsteen P, Mex DI, Clark E, Muster J, Robitaille AM, Sivaram G, Abell L, Goodson JM, Pranoto I, Madan A, Chin MT, Tian R, Murry CE, Moon RT, Wang Y, Ruohola-Baker H.
PMID: 34988408
iScience. 2021 Dec 06;25(1):103574. doi: 10.1016/j.isci.2021.103574. eCollection 2022 Jan 21.

Heart disease is the leading cause of death with no method to repair damaged myocardium due to the limited proliferative capacity of adult cardiomyocytes. Curiously, mouse neonates and zebrafish can regenerate their hearts via cardiomyocyte de-differentiation and proliferation. However,...

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Miklas JW, Levy S, Hofsteen P, et al. Amino acid primed mTOR activity is essential for heart regeneration. iScience. 2021;25(1):103574doi: 10.1016/j.isci.2021.103574.
Miklas, J. W., Levy, S., Hofsteen, P., Mex, D. I., Clark, E., Muster, J., Robitaille, A. M., Sivaram, G., Abell, L., Goodson, J. M., Pranoto, I., Madan, A., Chin, M. T., Tian, R., Murry, C. E., Moon, R. T., Wang, Y., & Ruohola-Baker, H. (2022). Amino acid primed mTOR activity is essential for heart regeneration. iScience, 25(1), 103574. https://doi.org/10.1016/j.isci.2021.103574
Miklas, Jason W, et al. "Amino acid primed mTOR activity is essential for heart regeneration." iScience vol. 25,1 (2022): 103574. doi: https://doi.org/10.1016/j.isci.2021.103574
Miklas JW, Levy S, Hofsteen P, Mex DI, Clark E, Muster J, Robitaille AM, Sivaram G, Abell L, Goodson JM, Pranoto I, Madan A, Chin MT, Tian R, Murry CE, Moon RT, Wang Y, Ruohola-Baker H. Amino acid primed mTOR activity is essential for heart regeneration. iScience. 2021 Dec 06;25(1):103574. doi: 10.1016/j.isci.2021.103574. eCollection 2022 Jan 21. PMID: 34988408; PMCID: PMC8704488.
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Racial/Ethnic Inequities in Paid Parental Leave Access.

Health equity

Goodman JM, Williams C, Dow WH.
PMID: 34909544
Health Equity. 2021 Oct 13;5(1):738-749. doi: 10.1089/heq.2021.0001. eCollection 2021.

No abstract available.

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Goodman JM, Williams C, Dow WH. Racial/Ethnic Inequities in Paid Parental Leave Access. Health Equity. 2021;5(1):738-749doi: 10.1089/heq.2021.0001.
Goodman, J. M., Williams, C., & Dow, W. H. (2021). Racial/Ethnic Inequities in Paid Parental Leave Access. Health equity, 5(1), 738-749. https://doi.org/10.1089/heq.2021.0001
Goodman, Julia M, et al. "Racial/Ethnic Inequities in Paid Parental Leave Access." Health equity vol. 5,1 (2021): 738-749. doi: https://doi.org/10.1089/heq.2021.0001
Goodman JM, Williams C, Dow WH. Racial/Ethnic Inequities in Paid Parental Leave Access. Health Equity. 2021 Oct 13;5(1):738-749. doi: 10.1089/heq.2021.0001. eCollection 2021. PMID: 34909544; PMCID: PMC8665807.
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Showing 301 to 307 of 307 entries