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Showing 25 to 36 of 41 entries
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Student performance on the Test of Scientific Literacy Skills (TOSLS) does not change with assignment of a low-stakes grade.

BMC research notes

Segarra VA, Hughes NM, Ackerman KM, Grider MH, Lyda T, Vigueira PA.
PMID: 29970190
BMC Res Notes. 2018 Jul 03;11(1):422. doi: 10.1186/s13104-018-3545-9.

OBJECTIVE: Response-validated multiple-choice assessments are used in college courses to assess student learning gains. The ability of a test to accurately reflect student learning gains is highly dependent on the students' effort. Within our institution, lackluster student effort is...

OpenMPIData: An initiative for freely accessible magnetic particle imaging data.

Data in brief

Knopp T, Szwargulski P, Griese F, Gräser M.
PMID: 31890809
Data Brief. 2019 Dec 11;28:104971. doi: 10.1016/j.dib.2019.104971. eCollection 2020 Feb.

Magnetic particle imaging is a tomographic imaging technique capable of measuring the local concentration of magnetic nanoparticles that can be used as tracers in biomedical applications. Since MPI is still at a very early stage of development, there are...

Quantitative evaluation of variance in secondary dentition eruption among ethnic groups in Hawai'i.

Hawaii dental journal

Greer MH, Loo KJ.
PMID: 18711874
Hawaii Dent J. 2008 Mar-Apr;39(2):4-9; quiz 17.

Though little scientific evidence existed to support the belief among dentists who treat Pacific Islander populations that many children of the region erupt secondary teeth earlier and at an eruption rate which exceeds Caucasian children. Based upon a data...

Random walk and directed movement: Comparison between inert particles and self-organized molecular machines.

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics

Franke K, Gruler H, Schienbein M.
PMID: 9961873
Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1994 Jun;49(6):5462-5471. doi: 10.1103/physreve.49.5462.

No abstract available.

Chemical amplifier, self-ignition mechanism, and amoeboid cell migration.

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics

Gruler H, Schienbein M.
PMID: 9963890
Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1995 Oct;52(4):4183-4197. doi: 10.1103/physreve.52.4183.

No abstract available.

Intracellularly Released Cholesterol from Polymer-Based Delivery Systems Alters Cellular Responses to Pneumolysin and Promotes Cell Survival.

Metabolites

Kammann T, Hoff J, Yildirim I, Shkodra B, Müller T, Weber C, Gräler MH, Maus UA, Paton JC, Singer M, Traeger A, Schubert US, Bauer M, Press AT.
PMID: 34940579
Metabolites. 2021 Nov 30;11(12). doi: 10.3390/metabo11120821.

Cholesterol is highly abundant within all human body cells and modulates critical cellular functions related to cellular plasticity, metabolism, and survival. The cholesterol-binding toxin pneumolysin represents an essential virulence factor of

Intracellularly Released Cholesterol from Polymer-Based Delivery Systems Alters Cellular Responses to Pneumolysin and Promotes Cell Survival.

Metabolites

Kammann T, Hoff J, Yildirim I, Shkodra B, Müller T, Weber C, Gräler MH, Maus UA, Paton JC, Singer M, Traeger A, Schubert US, Bauer M, Press AT.
PMID: 34940579
Metabolites. 2021 Nov 30;11(12). doi: 10.3390/metabo11120821.

Cholesterol is highly abundant within all human body cells and modulates critical cellular functions related to cellular plasticity, metabolism, and survival. The cholesterol-binding toxin pneumolysin represents an essential virulence factor of

Potential Impact of Statins on Neuronal Stress Responses in Patients at Risk for Cardiovascular Disease.

Journal of personalized medicine

Diggelmann F, Bengs S, Haider A, Epprecht G, Beeler AL, Etter D, Wijnen WJ, Portmann A, Warnock GI, Treyer V, Grämer M, Todorov A, Mikail N, Rossi A, Fuchs TA, Pazhenkottil AP, Buechel RR, Tanner FC, Kaufmann PA, Gebhard C, Fiechter M.
PMID: 33916056
J Pers Med. 2021 Apr 01;11(4). doi: 10.3390/jpm11040261.

BACKGROUND: Recent studies indicate that enhanced neuronal stress responses are associated with adverse cardiovascular outcomes. A chronic inflammatory state seems to mediate this detrimental neuro-cardiac communication. Statins are among the most widely prescribed medications in primary and secondary cardiovascular...

Immunoreactivity of the SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in murine models of hormonal manipulation, ageing, and cardiac injury.

Scientific reports

Bengs S, Rossi A, Haberecker M, Mikail N, Meisel A, Haider A, Grämer M, Portmann A, Todorov A, Schönenberger C, Gebhard CE, Kuster GM, Regitz-Zagrosek V, Gebhard C.
PMID: 34907257
Sci Rep. 2021 Dec 14;11(1):23993. doi: 10.1038/s41598-021-03181-3.

Previous work indicates that SARS-CoV-2 virus entry proteins angiotensin-converting enzyme 2 (ACE-2) and the cell surface transmembrane protease serine 2 (TMPRSS-2) are regulated by sex hormones. However, clinical studies addressing this association have yielded conflicting results. We sought to...

Sphingolipidomics in Translational Sepsis Research-Biomedical Considerations and Perspectives.

Frontiers in medicine

Claus RA, Graeler MH.
PMID: 33553212
Front Med (Lausanne). 2021 Jan 20;7:616578. doi: 10.3389/fmed.2020.616578. eCollection 2020.

No abstract available.

Activation of Sphingomyelinase-Ceramide-Pathway in COVID-19 Purposes Its Inhibition for Therapeutic Strategies.

Frontiers in immunology

Abusukhun M, Winkler MS, Pöhlmann S, Moerer O, Meissner K, Tampe B, Hofmann-Winkler H, Bauer M, Gräler MH, Claus RA.
PMID: 34987511
Front Immunol. 2021 Dec 20;12:784989. doi: 10.3389/fimmu.2021.784989. eCollection 2021.

Effective treatment strategies for severe coronavirus disease (COVID-19) remain scarce. Hydrolysis of membrane-embedded, inert sphingomyelin by stress responsive sphingomyelinases is a hallmark of adaptive responses and cellular repair. As demonstrated in experimental and observational clinical studies, the transient and...

The role of sphingosine 1-phosphate in immunity and sepsis.

American journal of clinical and experimental immunology

Gräler MH.
PMID: 23885318
Am J Clin Exp Immunol. 2012 Sep 27;1(2):90-100. Print 2012.

Sphingosine 1-phosphate (S1P) is a lipid metabolite with intra- and extracellular signalling properties. It activates five G protein-coupled cell surface receptors designated S1P-receptors type 1-5 (S1P1-5) that transmit extracellular signals into cells, and it modulates intracellular signalling as a...

Showing 25 to 36 of 41 entries