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Showing 25 to 36 of 196 entries
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Leptospirosis infections among hospital patients, Sarawak, Malaysia.

Tropical diseases, travel medicine and vaccines

Hii KC, Robie ER, Saihidi I, Berita A, Alarja NA, Xiu L, Merchant JA, Binder RA, Goh JK, Guernier-Cambert V, Galán D, Gregory MJ, Gray GC.
PMID: 34719397
Trop Dis Travel Med Vaccines. 2021 Nov 01;7(1):32. doi: 10.1186/s40794-021-00154-2.

BACKGROUND: Leptospirosis diagnoses have increased in Sarawak, Malaysia in recent years.METHODS: To better understand the burden of disease and associated risk factors, we evaluated 147 patients presenting with clinical leptospirosis to local hospitals in Sarawak, Malaysia for the presence...

Tracking tick-borne diseases in Mongolian livestock using next generation sequencing (NGS).

Ticks and tick-borne diseases

Chaorattanakawee S, Wofford RN, Takhampunya R, Katherine Poole-Smith B, Boldbaatar B, Lkhagvatseren S, Altantogtokh D, Musih E, Nymadawa P, Davidson S, Hertz J, Fiorenzano J, Gray GC, von Fricken ME.
PMID: 34689003
Ticks Tick Borne Dis. 2022 Jan;13(1):101845. doi: 10.1016/j.ttbdis.2021.101845. Epub 2021 Oct 10.

The livestock industry in Mongolia accounts for 24% of national revenue, with one third of the population maintaining a pastoral lifestyle. This close connection between Mongolian population and livestock is a major concern for pathogen transfer, especially given the...

Testing Black-White disparities in biological aging in older adults in the United States: analysis of DNA-methylation and blood-chemistry methods.

American journal of epidemiology

Graf GH, Crowe CL, Kothari M, Kwon D, Manly JJ, Turney IC, Valeri L, Belsky DW.
PMID: 34850809
Am J Epidemiol. 2021 Dec 01; doi: 10.1093/aje/kwab281. Epub 2021 Dec 01.

Biological aging is a proposed mechanism through which social determinants drive health disparities. We conducted proof-of-concept testing of eight DNA-methylation and blood-chemistry quantifications of biological aging as mediators of disparities in healthspan between Black and White participants in the...

Animals as potential reservoirs for dengue transmission: A systematic review.

One health (Amsterdam, Netherlands)

Gwee SXW, St John AL, Gray GC, Pang J.
PMID: 33598525
One Health. 2021 Jan 20;12:100216. doi: 10.1016/j.onehlt.2021.100216. eCollection 2021 Jun.

Dengue is a rapidly spreading mosquito-borne flavivirus infection that is prevalent in tropical and sub-tropical regions. Humans are known to be the main reservoir host maintaining the epidemic cycles of dengue but it is unclear if dengue virus is...

Are In Vitro Human Blood-Brain-Tumor-Barriers Suitable Replacements for In Vivo Models of Brain Permeability for Novel Therapeutics?.

Cancers

Prashanth A, Donaghy H, Stoner SP, Hudson AL, Wheeler HR, Diakos CI, Howell VM, Grau GE, McKelvey KJ.
PMID: 33668807
Cancers (Basel). 2021 Feb 25;13(5). doi: 10.3390/cancers13050955.

BACKGROUND: High grade gliomas (HGG) are incapacitating and prematurely fatal diseases. To overcome the poor prognosis, novel therapies must overcome the selective and restricted permeability of the blood-brain barrier (BBB). This study critically evaluated whether in vitro human normal...

Calculated parenteral initial treatment of bacterial infections: Introduction and antibiotics.

GMS infectious diseases

Bodmann KF, Kresken M, Grabein B, Dohmen PM, Wilke M.
PMID: 32373444
GMS Infect Dis. 2020 Mar 26;8:Doc19. doi: 10.3205/id000063. eCollection 2020.

This is the first chapter of the guideline "Calculated initial parenteral treatment of bacterial infections in adults - update 2018" in the 2

S2k guideline "Calculated parenteral initial treatment of bacterial infections in adults - update 2018", 2.

GMS infectious diseases

Bodmann KF, Grabein B, Kresken M.
PMID: 32373445
GMS Infect Dis. 2020 Mar 26;8:Doc20. doi: 10.3205/id000064. eCollection 2020.

No abstract available.

Calculated parenteral initial treatment of bacterial infections: Microbiology.

GMS infectious diseases

Kresken M, Grabein B, Becker K, Straube E, Wichelhaus TA, Willinger B.
PMID: 32373443
GMS Infect Dis. 2020 Mar 26;8:Doc18. doi: 10.3205/id000062. eCollection 2020.

This is the second chapter of the guideline "Calculated initial parenteral treatment of bacterial infections in adults - update 2018" in the 2

Role of Protein-Water Interface in the Stacking Interactions of Granum Thylakoid Membranes-As Revealed by the Effects of Hofmeister Salts.

Frontiers in plant science

Zsiros O, Ünnep R, Nagy G, Almásy L, Patai R, Székely NK, Kohlbrecher J, Garab G, Dér A, Kovács L.
PMID: 32922427
Front Plant Sci. 2020 Aug 14;11:1257. doi: 10.3389/fpls.2020.01257. eCollection 2020.

The thylakoid membranes of vascular plants are differentiated into stacked granum and unstacked stroma regions. The formation of grana is triggered by the macrodomain formation of photosystem II and light-harvesting complex II (PSII-LHCII) and thus their lateral segregation from...

Organotypic Co-Cultures as a Novel 3D Model for Head and Neck Squamous Cell Carcinoma.

Cancers

Engelmann L, Thierauf J, Koerich Laureano N, Stark HJ, Prigge ES, Horn D, Freier K, Grabe N, Rong C, Federspil P, Zaoui K, Plinkert PK, Rotter N, von Knebel Doeberitz M, Hess J, Affolter A.
PMID: 32824777
Cancers (Basel). 2020 Aug 18;12(8). doi: 10.3390/cancers12082330.

No abstract available.

Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma.

Cancers

Hoefflin R, Harlander S, Abhari BA, Peighambari A, Adlesic M, Seidel P, Zodel K, Haug S, Göcmen B, Li Y, Lahrmann B, Grabe N, Heide D, Boerries M, Köttgen A, Heikenwalder M, Frew IJ.
PMID: 34638286
Cancers (Basel). 2021 Sep 25;13(19). doi: 10.3390/cancers13194801.

Specific inhibitors of HIF-2α have recently been approved for the treatment of ccRCC in VHL disease patients and have shown encouraging results in clinical trials for metastatic sporadic ccRCC. However, not all patients respond to therapy and pre-clinical and...

Cognitive Impairment and Physical Frailty in Patients With Cirrhosis.

Hepatology communications

Berry K, Duarte-Rojo A, Grab JD, Dunn MA, Boyarsky BJ, Verna EC, Kappus MR, Volk ML, McAdams-DeMarco M, Segev DL, Ganger DR, Ladner DP, Shui A, Tincopa MA, Rahimi RS, Lai JC.
PMID: 34558844
Hepatol Commun. 2022 Jan;6(1):237-246. doi: 10.1002/hep4.1796. Epub 2021 Aug 24.

Physical frailty and impaired cognition are common in patients with cirrhosis. Physical frailty can be assessed using performance-based tests, but the extent to which impaired cognition may impact performance is not well characterized. We assessed the relationship between impaired...

Showing 25 to 36 of 196 entries