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Showing 25 to 36 of 191 entries
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Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice.

Current developments in nutrition

Beaver LM, Lӧhr CV, Clarke JD, Glasser ST, Watson GW, Wong CP, Zhang Z, Williams DE, Dashwood RH, Shannon J, Thuillier P, Ho E.
PMID: 30019025
Curr Dev Nutr. 2017 Dec 26;2(3):nzy002. doi: 10.1093/cdn/nzy002. eCollection 2018 Mar.

BACKGROUND: Cruciferous vegetables have been associated with the chemoprevention of cancer. Epigenetic regulators have been identified as important targets for prostate cancer chemoprevention. Treatment of human prostate cancer cells with sulforaphane (SFN), a chemical from broccoli and broccoli sprouts,...

Editorial for "Long-Term Health Effects of the 9/11 Disaster" in .

International journal of environmental research and public health

Brackbill RM, Graber JM, Robison WAA.
PMID: 31500226
Int J Environ Res Public Health. 2019 Sep 07;16(18). doi: 10.3390/ijerph16183289.

The call for articles on the long term health effects of the 11 September 2001 terrorist attacks (9/11) has resulted in twenty-three papers that add a significant amount of information to the growing body of research on the effects...

Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer.

Molecular therapy : the journal of the American Society of Gene Therapy

Schirmer AU, Driver LM, Zhao MT, Wells CI, Pickett JE, O'Bryne SN, Eduful BJ, Yang X, Howard L, You S, Devi GR, DiGiovanni J, Freedland SJ, Chi JT, Drewry DH, Macias E.
PMID: 34450249
Mol Ther. 2022 Jan 05;30(1):485-500. doi: 10.1016/j.ymthe.2021.08.029. Epub 2021 Aug 25.

Serine/threonine kinase 3 (STK3) is an essential member of the highly conserved Hippo tumor suppressor pathway that regulates Yes-associated protein 1 (YAP1) and TAZ. STK3 and its paralog STK4 initiate a phosphorylation cascade that regulates YAP1/TAZ inhibition and degradation,...

Fundamental Biomaterial Considerations in the Development of a 3D Model Representative of Primary Open Angle Glaucoma.

Bioengineering (Basel, Switzerland)

Lamont HC, Masood I, Grover LM, El Haj AJ, Hill LJ.
PMID: 34821713
Bioengineering (Basel). 2021 Oct 20;8(11). doi: 10.3390/bioengineering8110147.

Glaucoma is a leading cause of irreversible blindness globally, with primary open angle glaucoma (POAG) being the most common subset. Raised intraocular pressure is an important risk factor for POAG and is caused by a reduction in aqueous humour...

The effect of primary care policy changes on hospitalisation for ambulatory care sensitive conditions: notes from Brazil.

Public health

Mendonça Guimarães R, Pimenta Ribeiro Dos Santos L, Gonçalves Pereira A, Graever L.
PMID: 34742114
Public Health. 2021 Dec;201:26-34. doi: 10.1016/j.puhe.2021.09.028. Epub 2021 Nov 02.

OBJECTIVES: The aim of this study was to assess the effect of the Primary Health Care Reform and the impact of recent national policy changes on the trend in hospitalisation rates for Ambulatory Conditions Sensitive to Primary Care (ACSC)...

A Review of Systemic Minocycline Side Effects and Topical Minocycline as a Safer Alternative for Treating Acne and Rosacea.

Antibiotics (Basel, Switzerland)

Martins AM, Marto JM, Johnson JL, Graber EM.
PMID: 34206485
Antibiotics (Basel). 2021 Jun 22;10(7). doi: 10.3390/antibiotics10070757.

Resistance of

Dysgeusia induced and resolved by focused ultrasound thalamotomy: case report.

Journal of neurosurgery

De Vloo P, Boutet A, Elias GJB, Gramer RM, Joel SE, Llinas M, Kucharczyk W, Fasano A, Hamani C, Lozano AM.
PMID: 34144526
J Neurosurg. 2021 Jun 18;136(1):215-220. doi: 10.3171/2020.11.JNS202882. Print 2022 Jan 01.

Dysgeusia, or distorted taste, has recently been acknowledged as a complication of thalamic ablation or thalamic deep brain stimulation as a treatment of tremor. In a unique patient, left-sided MR-guided focused ultrasound thalamotomy improved right-sided essential tremor but also...

Formulation of a reactive oxygen producing calcium sulphate cement as an anti-bacterial hard tissue scaffold.

Scientific reports

Hall TJ, Hughes EAB, Sajjad H, Kuehne SA, Grant MM, Grover LM, Cox SC.
PMID: 33627825
Sci Rep. 2021 Feb 24;11(1):4491. doi: 10.1038/s41598-021-84060-9.

Prophylactic antibiotic bone cements are extensively used in orthopaedics. However, the development of antimicrobial resistance to antibiotics, demonstrates a need to find alternative treatments. Herein, an antimicrobial honey (SurgihoneyRO-SHRO) has been successfully incorporated into a calcium sulphate (CS) based...

NUAK family kinase 2 is a novel therapeutic target for prostate cancer.

Molecular carcinogenesis

Fu W, Zhao MT, Driver LM, Schirmer AU, Yin Q, You S, Freedland SJ, DiGiovanni J, Drewry DH, Macias E.
PMID: 34818445
Mol Carcinog. 2021 Nov 24; doi: 10.1002/mc.23374. Epub 2021 Nov 24.

Current advancements in prostate cancer (PC) therapies have been successful in slowing PC progression and increasing life expectancy; however, there is still no curative treatment for advanced metastatic castration resistant PC (mCRPC). Most treatment options target the androgen receptor,...

Commentary on: Dror IE, Melinek J, Arden JL, Kukucka J, Hawkins S, Carter J, et al. Cognitive bias in forensic pathology decisions. J Forensic Sci. https://doi.org/10.1111/1556-4029.14697. Epub 2021 Feb 20.

Journal of forensic sciences

Graber ML.
PMID: 34498751
J Forensic Sci. 2021 Nov;66(6):2574. doi: 10.1111/1556-4029.14857. Epub 2021 Sep 09.

No abstract available.

Hybrid reflection retrieval method for terahertz dielectric imaging of human bone.

Biomedical optics express

Freer S, Sui C, Hanham SM, Grover LM, Navarro-Cía M.
PMID: 34513226
Biomed Opt Express. 2021 Jul 12;12(8):4807-4820. doi: 10.1364/BOE.427648. eCollection 2021 Aug 01.

Terahertz imaging is becoming a biological imaging modality in its own right, alongside the more mature infrared and X-ray techniques. Nevertheless, extraction of hyperspectral, biometric information of samples is limited by experimental challenges. Terahertz time domain spectroscopy reflection measurements...

Osteoblast-Derived Vesicle Protein Content Is Temporally Regulated During Osteogenesis: Implications for Regenerative Therapies.

Frontiers in bioengineering and biotechnology

Davies OG, Cox SC, Azoidis I, McGuinness AJA, Cooke M, Heaney LM, Davis ET, Jones SW, Grover LM.
PMID: 31119130
Front Bioeng Biotechnol. 2019 May 01;7:92. doi: 10.3389/fbioe.2019.00092. eCollection 2019.

Osteoblast-derived extracellular vesicles (EV) are a collection of secreted (sEVs) and matrix-bound nanoparticles that function as foci for mineral nucleation and accumulation. Due to the fact sEVs can be isolated directly from the culture medium of mineralizing osteoblasts, there...

Showing 25 to 36 of 191 entries