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Showing 1501 to 1508 of 1508 entries
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Prognostic value of heart rate reserve in patients with suspected coronary artery disease undergoing stress myocardial perfusion imaging.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Nappi C, Petretta M, Assante R, Zampella E, Gaudieri V, Cantoni V, Green R, Volpe F, Piscopo L, Mainolfi CG, Nicolai E, Acampa W, Cuocolo A.
PMID: 34346030
J Nucl Cardiol. 2021 Aug 03; doi: 10.1007/s12350-021-02743-2. Epub 2021 Aug 03.

BACKGROUND: Chronotropic incompetence is common in patients with cardiovascular disease and is associated with increased risk of adverse events. We assessed the incremental prognostic value of heart rate reserve (HRR) over stress myocardial perfusion single-photon emission computed tomography (MPS)...

Impact of Risk-Stratified Therapy on Health Status in Survivors of Childhood Acute Lymphoblastic Leukemia: A Report from the Childhood Cancer Survivor Study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Dixon SB, Chen Y, Yasui Y, Pui CH, Hunger SP, Silverman LB, Ness KK, Green DM, Howell RM, Leisenring WM, Kadan-Lottick NS, Krull KR, Oeffinger KC, Neglia JP, Hudson MM, Robison LL, Mertens AC, Armstrong GT, Nathan PC.
PMID: 34697055
Cancer Epidemiol Biomarkers Prev. 2022 Jan;31(1):150-160. doi: 10.1158/1055-9965.EPI-21-0667. Epub 2021 Oct 25.

BACKGROUND: Prior studies have identified that survivors of childhood acute lymphoblastic leukemia (ALL) report poor health status. It is unknown how risk-stratified therapy impacts the health status of ALL survivors.METHODS: We estimated and compared the prevalence of self-reported poor...

The evolution of regulated cell death pathways in animals and their evasion by pathogens.

Physiological reviews

Tummers B, Green DR.
PMID: 34898294
Physiol Rev. 2022 Jan 01;102(1):411-454. doi: 10.1152/physrev.00002.2021.

The coevolution of host-pathogen interactions underlies many human physiological traits associated with protection from or susceptibility to infections. Among the mechanisms that animals utilize to control infections are the regulated cell death pathways of pyroptosis, apoptosis, and necroptosis. Over...

Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.

Journal of medicinal chemistry

Wilson C, Ray P, Zuccotto F, Hernandez J, Aggarwal A, Mackenzie C, Caldwell N, Taylor M, Huggett M, Mathieson M, Murugesan D, Smith A, Davis S, Cocco M, Parai MK, Acharya A, Tamaki F, Scullion P, Epemolu O, Riley J, Stojanovski L, Lopez-Román EM, Torres-Gómez PA, Toledo AM, Guijarro-Lopez L, Camino I, Engelhart CA, Schnappinger D, Massoudi LM, Lenaerts A, Robertson GT, Walpole C, Matthews D, Floyd D, Sacchettini JC, Read KD, Encinas L, Bates RH, Green SR, Wyatt PG.
PMID: 34910486
J Med Chem. 2022 Jan 13;65(1):409-423. doi: 10.1021/acs.jmedchem.1c01586. Epub 2021 Dec 15.

With increasing drug resistance in tuberculosis (TB) patient populations, there is an urgent need for new drugs. Ideally, new agents should work through novel targets so that they are unencumbered by preexisting clinical resistance to current treatments. Benzofuran

EZH2 inhibits NK cell-mediated antitumor immunity by suppressing CXCL10 expression in an HDAC10-dependent manner.

Proceedings of the National Academy of Sciences of the United States of America

Bugide S, Gupta R, Green MR, Wajapeyee N.
PMID: 34301901
Proc Natl Acad Sci U S A. 2021 Jul 27;118(30). doi: 10.1073/pnas.2102718118.

Enhancer of zeste homolog 2 (EZH2) is a histone H3 lysine 27 methyltransferase that has been shown to function as an oncogene in some cancers. Previous reports have largely focused on the ability of EZH2 to regulate cell-intrinsic tumor...

Early Operative Versus Delayed Operative Versus Nonoperative Treatment of Pediatric and Adolescent Anterior Cruciate Ligament Injuries: A Systematic Review and Meta-analysis.

The American journal of sports medicine

James EW, Dawkins BJ, Schachne JM, Ganley TJ, Kocher MS, Anderson CN, Busch MT, Chambers HG, Christino MA, Cordasco FA, Edmonds EW, Green DW, Heyworth BE, Lawrence JTR, Micheli LJ, Milewski MD, Matava MJ, Nepple JJ, Parikh SN, Pennock AT, Perkins CA, Saluan PM, Shea KG, Wall EJ, Willimon SC, Fabricant PD.
PMID: 33720764
Am J Sports Med. 2021 Dec;49(14):4008-4017. doi: 10.1177/0363546521990817. Epub 2021 Mar 15.

BACKGROUND: Treatment options for pediatric and adolescent anterior cruciate ligament (ACL) injuries include early operative, delayed operative, and nonoperative management. Currently, there is a lack of consensus regarding the optimal treatment for these injuries.PURPOSE/HYPOTHESIS: The purpose was to determine...

Clinical psychology students' perceptions of diversity training: a study of exposure and satisfaction.

Green D, Callands TA, Radcliffe AM, Luebbe AM, Klonoff EA.
UIID-AD: 3007
2009;65:1056-70. doi: 10.1002/jclp.20605.

This study examined clinical psychology graduate students' definitions of diversity and their perceptions of their exposure to and satisfaction regarding their level of diversity training. Four hundred and ninety-one students from Counsel of University Directors of Clinical Psychology (CUDCP)...

Designing and implementing a cultural competence OSCE: Lessons learned from interviews with medical students.

Krupat E, Green AR, Miller E, White A, Taylor WC, Hirsh DA, Wilson RP, Betancourt JR.
UIID-AD: 448
2007;17:344-350.

Purpose: Objective structured clinical examinations (OSCEs) use standardized patients (SPs) to teach and evaluate medical students ' skills. Few studies describe using OSCEs for cultural competence education, now a Liaison Committee on Medical Education accreditation standard for medical schools....

Showing 1501 to 1508 of 1508 entries