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Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Wolchok JD, Chiarion-Sileni V, Gonzalez R, Grob JJ, Rutkowski P, Lao CD, Cowey CL, Schadendorf D, Wagstaff J, Dummer R, Ferrucci PF, Smylie M, Butler MO, Hill A, Márquez-Rodas I, Haanen JBAG, Guidoboni M, Maio M, Schöffski P, Carlino MS, Lebbé C, McArthur G, Ascierto PA, Daniels GA, Long GV, Bas T, Ritchings C, Larkin J, Hodi FS.
PMID: 34818112
J Clin Oncol. 2022 Jan 10;40(2):127-137. doi: 10.1200/JCO.21.02229. Epub 2021 Nov 24.

PURPOSE: In the phase III CheckMate 067 trial, durable clinical benefit was demonstrated previously with nivolumab plus ipilimumab and nivolumab alone versus ipilimumab. Here, we report 6.5-year efficacy and safety outcomes.PATIENTS AND METHODS: Patients with previously untreated unresectable stage...

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Wolchok JD, Chiarion-Sileni V, Gonzalez R, et al. Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma. J Clin Oncol. 2021;40(2):127-137doi: 10.1200/JCO.21.02229.
Wolchok, J. D., Chiarion-Sileni, V., Gonzalez, R., Grob, J. J., Rutkowski, P., Lao, C. D., Cowey, C. L., Schadendorf, D., Wagstaff, J., Dummer, R., Ferrucci, P. F., Smylie, M., Butler, M. O., Hill, A., Márquez-Rodas, I., Haanen, J. B. A. G., Guidoboni, M., Maio, M., Schöffski, P., Carlino, M. S., Lebbé, C., McArthur, G., Ascierto, P. A., Daniels, G. A., Long, G. V., Bas, T., Ritchings, C., Larkin, J., & Hodi, F. S. (2022). Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 40(2), 127-137. https://doi.org/10.1200/JCO.21.02229
Wolchok, Jedd D, et al. "Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma." Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 40,2 (2022): 127-137. doi: https://doi.org/10.1200/JCO.21.02229
Wolchok JD, Chiarion-Sileni V, Gonzalez R, Grob JJ, Rutkowski P, Lao CD, Cowey CL, Schadendorf D, Wagstaff J, Dummer R, Ferrucci PF, Smylie M, Butler MO, Hill A, Márquez-Rodas I, Haanen JBAG, Guidoboni M, Maio M, Schöffski P, Carlino MS, Lebbé C, McArthur G, Ascierto PA, Daniels GA, Long GV, Bas T, Ritchings C, Larkin J, Hodi FS. Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma. J Clin Oncol. 2022 Jan 10;40(2):127-137. doi: 10.1200/JCO.21.02229. Epub 2021 Nov 24. PMID: 34818112; PMCID: PMC8718224.
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Pharmacogenetics of Opioid Use and Implications for Pain Management.

The journal of applied laboratory medicine

Nerenz RD, Tsongalis GJ.
PMID: 33636885
J Appl Lab Med. 2018 Jan 01;2(4):622-632. doi: 10.1373/jalm.2017.023150.

BACKGROUND: Opioid analgesics are frequently prescribed to manage acute and chronic pain, but individual differences in opioid response make effective pain control in all patients an elusive goal. Furthermore, the risk of addiction following opioid consumption varies among individual...

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Nerenz RD, Tsongalis GJ. Pharmacogenetics of Opioid Use and Implications for Pain Management. J Appl Lab Med. 2018;2(4):622-632doi: 10.1373/jalm.2017.023150.
Nerenz, R. D., & Tsongalis, G. J. (2018). Pharmacogenetics of Opioid Use and Implications for Pain Management. The journal of applied laboratory medicine, 2(4), 622-632. https://doi.org/10.1373/jalm.2017.023150
Nerenz, Robert D, and Tsongalis, Gregory J. "Pharmacogenetics of Opioid Use and Implications for Pain Management." The journal of applied laboratory medicine vol. 2,4 (2018): 622-632. doi: https://doi.org/10.1373/jalm.2017.023150
Nerenz RD, Tsongalis GJ. Pharmacogenetics of Opioid Use and Implications for Pain Management. J Appl Lab Med. 2018 Jan 01;2(4):622-632. doi: 10.1373/jalm.2017.023150. PMID: 33636885.
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Characterizing Microbiomes via Sequencing of Marker Loci: Techniques To Improve Throughput, Account for Cross-Contamination, and Reduce Cost.

mSystems

Harrison JG, Randolph GD, Buerkle CA.
PMID: 34254828
mSystems. 2021 Aug 31;6(4):e0029421. doi: 10.1128/mSystems.00294-21. Epub 2021 Jul 13.

New approaches to characterizing microbiomes via high-throughput sequencing provide impressive gains in efficiency and cost reduction compared to approaches that were standard just a few years ago. However, the speed of method development has been such that staying abreast...

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Harrison JG, Randolph GD, Buerkle CA. Characterizing Microbiomes via Sequencing of Marker Loci: Techniques To Improve Throughput, Account for Cross-Contamination, and Reduce Cost. mSystems. 2021;6(4):e0029421doi: 10.1128/mSystems.00294-21.
Harrison, J. G., Randolph, G. D., & Buerkle, C. A. (2021). Characterizing Microbiomes via Sequencing of Marker Loci: Techniques To Improve Throughput, Account for Cross-Contamination, and Reduce Cost. mSystems, 6(4), e0029421. https://doi.org/10.1128/mSystems.00294-21
Harrison, Joshua G, et al. "Characterizing Microbiomes via Sequencing of Marker Loci: Techniques To Improve Throughput, Account for Cross-Contamination, and Reduce Cost." mSystems vol. 6,4 (2021): e0029421. doi: https://doi.org/10.1128/mSystems.00294-21
Harrison JG, Randolph GD, Buerkle CA. Characterizing Microbiomes via Sequencing of Marker Loci: Techniques To Improve Throughput, Account for Cross-Contamination, and Reduce Cost. mSystems. 2021 Aug 31;6(4):e0029421. doi: 10.1128/mSystems.00294-21. Epub 2021 Jul 13. PMID: 34254828; PMCID: PMC8409480.
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Multireader evaluation of radiologist performance for COVID-19 detection on emergency department chest radiographs.

Clinical imaging

Gichoya JW, Sinha P, Davis M, Dunkle JW, Hamlin SA, Herr KD, Hoff CN, Letter HP, McAdams CR, Puthoff GD, Smith KL, Steenburg SD, Banerjee I, Trivedi H.
PMID: 34798562
Clin Imaging. 2021 Nov 12;82:77-82. doi: 10.1016/j.clinimag.2021.10.018. Epub 2021 Nov 12.

BACKGROUND: Chest radiographs (CXR) are frequently used as a screening tool for patients with suspected COVID-19 infection pending reverse transcriptase polymerase chain reaction (RT-PCR) results, despite recommendations against this. We evaluated radiologist performance for COVID-19 diagnosis on CXR at...

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Gichoya JW, Sinha P, Davis M, et al. Multireader evaluation of radiologist performance for COVID-19 detection on emergency department chest radiographs. Clin Imaging. 2021;82:77-82doi: 10.1016/j.clinimag.2021.10.018.
Gichoya, J. W., Sinha, P., Davis, M., Dunkle, J. W., Hamlin, S. A., Herr, K. D., Hoff, C. N., Letter, H. P., McAdams, C. R., Puthoff, G. D., Smith, K. L., Steenburg, S. D., Banerjee, I., & Trivedi, H. (2021). Multireader evaluation of radiologist performance for COVID-19 detection on emergency department chest radiographs. Clinical imaging, 8277-82. https://doi.org/10.1016/j.clinimag.2021.10.018
Gichoya, Judy W, et al. "Multireader evaluation of radiologist performance for COVID-19 detection on emergency department chest radiographs." Clinical imaging vol. 82 (2021): 77-82. doi: https://doi.org/10.1016/j.clinimag.2021.10.018
Gichoya JW, Sinha P, Davis M, Dunkle JW, Hamlin SA, Herr KD, Hoff CN, Letter HP, McAdams CR, Puthoff GD, Smith KL, Steenburg SD, Banerjee I, Trivedi H. Multireader evaluation of radiologist performance for COVID-19 detection on emergency department chest radiographs. Clin Imaging. 2021 Nov 12;82:77-82. doi: 10.1016/j.clinimag.2021.10.018. Epub 2021 Nov 12. PMID: 34798562; PMCID: PMC8585957.
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Polycyclic aromatic hydrocarbon contamination in soils and sediments: Sustainable approaches for extraction and remediation.

Chemosphere

Kariyawasam T, Doran GS, Howitt JA, Prenzler PD.
PMID: 34826448
Chemosphere. 2021 Nov 23;132981. doi: 10.1016/j.chemosphere.2021.132981. Epub 2021 Nov 23.

Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic environmental pollutants that are extremely hydrophobic in nature and resistant to biological degradation. Extraction of PAHs from environmental matrices is the first and most crucial step in PAH quantification. Extraction followed by quantification...

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Kariyawasam T, Doran GS, Howitt JA, et al. Polycyclic aromatic hydrocarbon contamination in soils and sediments: Sustainable approaches for extraction and remediation. Chemosphere. 2021;132981doi: 10.1016/j.chemosphere.2021.132981.
Kariyawasam, T., Doran, G. S., Howitt, J. A., & Prenzler, P. D. (2021). Polycyclic aromatic hydrocarbon contamination in soils and sediments: Sustainable approaches for extraction and remediation. Chemosphere, 132981. https://doi.org/10.1016/j.chemosphere.2021.132981
Kariyawasam, Thiloka, et al. "Polycyclic aromatic hydrocarbon contamination in soils and sediments: Sustainable approaches for extraction and remediation." Chemosphere vol. (2021): 132981. doi: https://doi.org/10.1016/j.chemosphere.2021.132981
Kariyawasam T, Doran GS, Howitt JA, Prenzler PD. Polycyclic aromatic hydrocarbon contamination in soils and sediments: Sustainable approaches for extraction and remediation. Chemosphere. 2021 Nov 23;132981. doi: 10.1016/j.chemosphere.2021.132981. Epub 2021 Nov 23. PMID: 34826448.
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Philomatry in plants: why do so many species have limited seed dispersal?.

American journal of botany

Cheplick GP.
PMID: 34679185
Am J Bot. 2021 Oct 22; doi: 10.1002/ajb2.1791. Epub 2021 Oct 22.

Many have noted limited seed dispersal of plants in diverse environments and attempted evolutionary explanations for it. Although philopatric ("love of fatherland") is used by zoologists to describe organisms that remain near their place of origin, philomatric ("love of...

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Cheplick GP. Philomatry in plants: why do so many species have limited seed dispersal?. Am J Bot. 2021;doi: 10.1002/ajb2.1791.
Cheplick, G. P. (2021). Philomatry in plants: why do so many species have limited seed dispersal?. American journal of botany, . https://doi.org/10.1002/ajb2.1791
Cheplick, Gregory P. "Philomatry in plants: why do so many species have limited seed dispersal?." American journal of botany vol. (2021). doi: https://doi.org/10.1002/ajb2.1791
Cheplick GP. Philomatry in plants: why do so many species have limited seed dispersal?. Am J Bot. 2021 Oct 22; doi: 10.1002/ajb2.1791. Epub 2021 Oct 22. PMID: 34679185.
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Malaria parasite infection compromises colonization resistance to an enteric pathogen by reducing gastric acidity.

Science advances

Walker GT, Yang G, Tsai JY, Rodriguez JL, English BC, Faber F, Souvannaseng L, Butler BP, Tsolis RM.
PMID: 34193410
Sci Adv. 2021 Jun 30;7(27). doi: 10.1126/sciadv.abd6232. Print 2021 Jun.

Malaria parasite infection weakens colonization resistance against

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Walker GT, Yang G, Tsai JY, et al. Malaria parasite infection compromises colonization resistance to an enteric pathogen by reducing gastric acidity. Sci Adv. 2021;7(27)doi: 10.1126/sciadv.abd6232.
Walker, G. T., Yang, G., Tsai, J. Y., Rodriguez, J. L., English, B. C., Faber, F., Souvannaseng, L., Butler, B. P., & Tsolis, R. M. (2021). Malaria parasite infection compromises colonization resistance to an enteric pathogen by reducing gastric acidity. Science advances, 7(27), . https://doi.org/10.1126/sciadv.abd6232
Walker, Gregory T, et al. "Malaria parasite infection compromises colonization resistance to an enteric pathogen by reducing gastric acidity." Science advances vol. 7,27 (2021). doi: https://doi.org/10.1126/sciadv.abd6232
Walker GT, Yang G, Tsai JY, Rodriguez JL, English BC, Faber F, Souvannaseng L, Butler BP, Tsolis RM. Malaria parasite infection compromises colonization resistance to an enteric pathogen by reducing gastric acidity. Sci Adv. 2021 Jun 30;7(27). doi: 10.1126/sciadv.abd6232. Print 2021 Jun. PMID: 34193410; PMCID: PMC8245046.
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What Are the Health Consequences of Upward Mobility?.

Annual review of psychology

Chen E, Brody GH, Miller GE.
PMID: 34579546
Annu Rev Psychol. 2022 Jan 04;73:599-628. doi: 10.1146/annurev-psych-033020-122814. Epub 2021 Sep 27.

Health disparities by socioeconomic status (SES) have been extensively documented, but less is known about the physical health implications of achieving upward mobility. This article critically reviews the evolving literature in this area, concluding that upward mobility is associated...

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Chen E, Brody GH, Miller GE. What Are the Health Consequences of Upward Mobility?. Annu Rev Psychol. 2021;73:599-628doi: 10.1146/annurev-psych-033020-122814.
Chen, E., Brody, G. H., & Miller, G. E. (2022). What Are the Health Consequences of Upward Mobility?. Annual review of psychology, 73599-628. https://doi.org/10.1146/annurev-psych-033020-122814
Chen, Edith, et al. "What Are the Health Consequences of Upward Mobility?." Annual review of psychology vol. 73 (2022): 599-628. doi: https://doi.org/10.1146/annurev-psych-033020-122814
Chen E, Brody GH, Miller GE. What Are the Health Consequences of Upward Mobility?. Annu Rev Psychol. 2022 Jan 04;73:599-628. doi: 10.1146/annurev-psych-033020-122814. Epub 2021 Sep 27. PMID: 34579546.
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Anticoagulation in cancer-associated thromboembolism with thrombocytopenia: a prospective, multicenter cohort study.

Blood advances

Carney BJ, Wang TF, Ren S, George G, Al Homssi A, Gaddh M, Connolly GC, Shah VI, Bogue T, Bartosic A, Neuberg D, Baumann Kreuziger L, Zwicker JI.
PMID: 34662892
Blood Adv. 2021 Dec 28;5(24):5546-5553. doi: 10.1182/bloodadvances.2021005966.

Venous thromboembolism (VTE) with concurrent thrombocytopenia is frequently encountered in patients with cancer. Therapeutic anticoagulation in the setting of thrombocytopenia is associated with a high risk of hemorrhage. Retrospective analyses suggest the utility of modified-dose anticoagulation in this population....

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Carney BJ, Wang TF, Ren S, et al. Anticoagulation in cancer-associated thromboembolism with thrombocytopenia: a prospective, multicenter cohort study. Blood Adv. 2021;5(24):5546-5553doi: 10.1182/bloodadvances.2021005966.
Carney, B. J., Wang, T. F., Ren, S., George, G., Al Homssi, A., Gaddh, M., Connolly, G. C., Shah, V. I., Bogue, T., Bartosic, A., Neuberg, D., Baumann Kreuziger, L., Zwicker, J. I. (2021). Anticoagulation in cancer-associated thromboembolism with thrombocytopenia: a prospective, multicenter cohort study. Blood advances, 5(24), 5546-5553. https://doi.org/10.1182/bloodadvances.2021005966
Carney, Brian J, et al. "Anticoagulation in cancer-associated thromboembolism with thrombocytopenia: a prospective, multicenter cohort study." Blood advances vol. 5,24 (2021): 5546-5553. doi: https://doi.org/10.1182/bloodadvances.2021005966
Carney BJ, Wang TF, Ren S, George G, Al Homssi A, Gaddh M, Connolly GC, Shah VI, Bogue T, Bartosic A, Neuberg D, Baumann Kreuziger L, Zwicker JI. Anticoagulation in cancer-associated thromboembolism with thrombocytopenia: a prospective, multicenter cohort study. Blood Adv. 2021 Dec 28;5(24):5546-5553. doi: 10.1182/bloodadvances.2021005966. PMID: 34662892; PMCID: PMC8714719.
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Lumbar Spine and Lower Extremity Overuse Injuries.

Physical medicine and rehabilitation clinics of North America

Isidro T, Gregory E, Lachman L, Isidro S, Cortez AN.
PMID: 34799000
Phys Med Rehabil Clin N Am. 2022 Feb;33(1):201-214. doi: 10.1016/j.pmr.2021.08.014. Epub 2021 Oct 25.

Both lower extremities and lower back are common sources of injury for cyclists. For providers to optimize care within this area of sports medicine, they need to understand the most common sources of injury in this population. Cycling presents...

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Isidro T, Gregory E, Lachman L, et al. Lumbar Spine and Lower Extremity Overuse Injuries. Phys Med Rehabil Clin N Am. 2021;33(1):201-214doi: 10.1016/j.pmr.2021.08.014.
Isidro, T., Gregory, E., Lachman, L., Isidro, S., & Cortez, A. N. (2022). Lumbar Spine and Lower Extremity Overuse Injuries. Physical medicine and rehabilitation clinics of North America, 33(1), 201-214. https://doi.org/10.1016/j.pmr.2021.08.014
Isidro, Tracey, et al. "Lumbar Spine and Lower Extremity Overuse Injuries." Physical medicine and rehabilitation clinics of North America vol. 33,1 (2022): 201-214. doi: https://doi.org/10.1016/j.pmr.2021.08.014
Isidro T, Gregory E, Lachman L, Isidro S, Cortez AN. Lumbar Spine and Lower Extremity Overuse Injuries. Phys Med Rehabil Clin N Am. 2022 Feb;33(1):201-214. doi: 10.1016/j.pmr.2021.08.014. Epub 2021 Oct 25. PMID: 34799000.
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Intravenous fluids for pain management in head and neck cancer patients undergoing chemoradiation.

Annals of translational medicine

Rivers CI, Iovoli AJ, Chatterjee U, Hermann GM, Singh AK.
PMID: 34164546
Ann Transl Med. 2021 May;9(10):912. doi: 10.21037/atm-20-3910.

BACKGROUND: Pain due to oral mucositis affects the majority of patients receiving chemoradiation (CRT) for head and neck cancer (HNC), and often results in dehydration. Anecdotally, intravenous (IV) fluids administered during treatment for the resultant dehydration was found to...

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Rivers CI, Iovoli AJ, Chatterjee U, et al. Intravenous fluids for pain management in head and neck cancer patients undergoing chemoradiation. Ann Transl Med. 2021;9(10):912doi: 10.21037/atm-20-3910.
Rivers, C. I., Iovoli, A. J., Chatterjee, U., Hermann, G. M., & Singh, A. K. (2021). Intravenous fluids for pain management in head and neck cancer patients undergoing chemoradiation. Annals of translational medicine, 9(10), 912. https://doi.org/10.21037/atm-20-3910
Rivers, Charlotte I, et al. "Intravenous fluids for pain management in head and neck cancer patients undergoing chemoradiation." Annals of translational medicine vol. 9,10 (2021): 912. doi: https://doi.org/10.21037/atm-20-3910
Rivers CI, Iovoli AJ, Chatterjee U, Hermann GM, Singh AK. Intravenous fluids for pain management in head and neck cancer patients undergoing chemoradiation. Ann Transl Med. 2021 May;9(10):912. doi: 10.21037/atm-20-3910. PMID: 34164546; PMCID: PMC8184454.
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Patterns of Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Among 1.6 Million Blood Donors: Impact of Vaccination, United States, December 2020-June 2021.

The Journal of infectious diseases

Dodd RY, Notari EP, Brodsky JP, Foster GA, Xu M, Saá P, Stramer SL.
PMID: 34626465
J Infect Dis. 2022 Jan 05;225(1):5-9. doi: 10.1093/infdis/jiab514.

From December 2020 to June 2021, 1654487 blood donors were tested for antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) S1 protein, and 1028547 (62.17%) were reactive. A rapid increase in prevalence was due to vaccination. Among a...

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Dodd RY, Notari EP, Brodsky JP, et al. Patterns of Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Among 1.6 Million Blood Donors: Impact of Vaccination, United States, December 2020-June 2021. J Infect Dis. 2022;225(1):5-9doi: 10.1093/infdis/jiab514.
Dodd, R. Y., Notari, E. P., Brodsky, J. P., Foster, G. A., Xu, M., Saá, P., & Stramer, S. L. (2022). Patterns of Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Among 1.6 Million Blood Donors: Impact of Vaccination, United States, December 2020-June 2021. The Journal of infectious diseases, 225(1), 5-9. https://doi.org/10.1093/infdis/jiab514
Dodd, Roger Y, et al. "Patterns of Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Among 1.6 Million Blood Donors: Impact of Vaccination, United States, December 2020-June 2021." The Journal of infectious diseases vol. 225,1 (2022): 5-9. doi: https://doi.org/10.1093/infdis/jiab514
Dodd RY, Notari EP, Brodsky JP, Foster GA, Xu M, Saá P, Stramer SL. Patterns of Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Among 1.6 Million Blood Donors: Impact of Vaccination, United States, December 2020-June 2021. J Infect Dis. 2022 Jan 05;225(1):5-9. doi: 10.1093/infdis/jiab514. PMID: 34626465.
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Showing 9985 to 9996 of 12675 entries