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Showing 1681 to 1689 of 1689 entries
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Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2.

bioRxiv : the preprint server for biology

Clark SA, Clark LE, Pan J, Coscia A, McKay LGA, Shankar S, Johnson RI, Griffiths A, Abraham J.
PMID: 33200128
bioRxiv. 2020 Nov 13; doi: 10.1101/2020.11.13.381533.

The SARS-CoV-2 viral spike (S) protein mediates attachment and entry into host cells and is a major target of vaccine and drug design. Potent SARS-CoV-2 neutralizing antibodies derived from closely related antibody heavy chain genes (IGHV3-53 or 3-66) have...

The Impact of a Centralised Pancreatic Cancer Service: a Case Study of Wales, UK.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Mowbray NG, Griffiths R, Akbari A, Hutchings H, Jenkins G, Al-Sarireh B.
PMID: 34506014
J Gastrointest Surg. 2021 Sep 10; doi: 10.1007/s11605-020-04612-8. Epub 2021 Sep 10.

INTRODUCTION: The centralisation of pancreatic cancer (PC) services still varies worldwide. This study aimed to assess the impact that a centralisation has had on patients in South Wales, UK.METHODS: A retrospective cohort analysis of patients in South Wales, UK,...

Metacognitive training modified for negative symptoms: A feasibility study.

Clinical psychology & psychotherapy

Swanson L, Schwannauer M, Bird T, Eliasson E, Millar A, Moritz S, Griffiths H.
PMID: 34792834
Clin Psychol Psychother. 2021 Nov 18; doi: 10.1002/cpp.2692. Epub 2021 Nov 18.

OBJECTIVE: Although patients often prioritize the treatment of negative symptoms, few psychological interventions targeting negative symptoms exist. This study attempts to fill this gap by piloting a modified metacognitive training programme, specifically targeted at negative symptoms (MCT-N), with a...

Trace Metal Residues in Marine Mussels: A Global Survey.

Environmental toxicology and chemistry

Cledon M, Tremblay LA, Griffiths C, Fadhlaoui M, Champeau O, Albentosa M, Besada V, Fernandez VH, McKindsey CW, Bendell LI, Zhang B, Garcia-Esquivel Z, Curiel S, Brar SK, Kumar P, Laroche O, Couture P.
PMID: 34606656
Environ Toxicol Chem. 2021 Dec;40(12):3434-3440. doi: 10.1002/etc.5228. Epub 2021 Nov 08.

Pressures from anthropogenic activities are causing degradation of estuarine and coastal ecosystems around the world. Trace metals are key pollutants that are released and can partition in a range of environmental compartments, to be ultimately accumulated in exposed biota....

Fecal SARS-CoV-2 RNA is associated with decreased COVID-19 survival.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Das Adhikari U, Eng G, Farcasanu M, Avena LE, Choudhary MC, Triant VA, Flagg M, Schiff AE, Gomez I, Froehle LM, Diefenbach TJ, Ronsard L, Lingwood D, Lee GC, Rabi SA, Erstad D, Velmahos G, Li JZ, Hodin R, Stone JR, Honko AN, Griffiths A, Yilmaz O, Kwon DS.
PMID: 34245255
Clin Infect Dis. 2021 Jul 10; doi: 10.1093/cid/ciab623. Epub 2021 Jul 10.

The clinical significance of SARS CoV-2 RNA in stool remains uncertain. We found that extrapulmonary dissemination of infection to the gastrointestinal (GI) tract, assessed by the presence of SARS-CoV-2 RNA in stool, is associated with decreased COVID-19 survival. Measurement...

Improving safety and reducing error in endoscopy (ISREE): a survey of UK services.

Frontline gastroenterology

Ravindran S, Bassett P, Shaw T, Dron M, Broughton R, Griffiths H, Keen D, Wood E, Healey CJ, Green J, Ashrafian H, Darzi A, Coleman M, Thomas-Gibson S.
PMID: 34917317
Frontline Gastroenterol. 2020 Aug 19;12(7):593-600. doi: 10.1136/flgastro-2020-101561. eCollection 2021.

BACKGROUND: The Joint Advisory Group on Gastrointestinal Endoscopy (JAG) 'Improving Safety and Reducing Error in Endoscopy' (ISREE) strategy was developed in 2018. In line with the strategy, a survey was conducted within the JAG census in 2019 to gain...

The Mediating Effects of Fear of COVID-19 and Depression on the Association Between Intolerance of Uncertainty and Emotional Eating During the COVID-19 Pandemic in Turkey.

International journal of mental health and addiction

Pak H, Süsen Y, Denizci Nazlıgül M, Griffiths M.
PMID: 33564278
Int J Ment Health Addict. 2021 Feb 04;1-15. doi: 10.1007/s11469-021-00489-z. Epub 2021 Feb 04.

The COVID-19 pandemic has greatly affected the mental health of individuals due to severe changes in their normal life routines. These changes might give rise to stress-induced factors and result in developing maladaptive behaviors. Therefore, the present study tested...

Feedback on feedback: a two-way street between residents and preceptors.

Canadian medical education journal

Griffiths J, Schultz K, Han H, Dalgarno N.
PMID: 33680229
Can Med Educ J. 2021 Feb 26;12(1):e32-e45. doi: 10.36834/cmej.69913. eCollection 2021 Feb.

BACKGROUND: Workplace-based assessment (WBA), foundational to competency-based medical education, relies on preceptors providing feedback to residents. Preceptors however get little timely, formative, specific, actionable feedback on the effectiveness of that feedback. Our study aimed to identify useful qualities of...

Experiences of pregnant women and healthcare professionals of participating in a digital antenatal CMV education intervention.

Midwifery

Montague A, Vandrevala T, Calvert A, Yeh LL, Star C, Khalil A, Griffiths P, Heath PT, Jones CE.
PMID: 35032932
Midwifery. 2022 Jan 06;106:103249. doi: 10.1016/j.midw.2022.103249. Epub 2022 Jan 06.

OBJECTIVE: The study aimed to explore the perspectives of participating pregnant women and Health Care Professionals (HCPs) towards receiving and providing cytomegalovirus (CMV) education so that barriers and facilitators towards incorporating CMV in routine antenatal care could be better...

Showing 1681 to 1689 of 1689 entries