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Showing 169 to 172 of 172 entries
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Development of Persistent Opioid Use After Cardiac Surgery.

JAMA cardiology

Brown CR, Chen Z, Khurshan F, Groeneveld PW, Desai ND.
PMID: 32584934
JAMA Cardiol. 2020 Aug 01;5(8):889-896. doi: 10.1001/jamacardio.2020.1445.

IMPORTANCE: The overuse of opioids for acute pain management has led to an epidemic of persistent opioid use.OBJECTIVE: To determine the proportion of opioid-naive patients who develop persistent opioid use after cardiac surgery and investigate the association between the...

Kinetics of myelin breakdown products: A labeling study in patients with progressive multiple sclerosis.

Clinical and translational science

Kanhai KMS, Goulooze SC, van der Grond J, Harms AC, Hankemeier T, Verma A, Dent G, Chavez J, Meijering H, Groeneveld GJ.
PMID: 34799987
Clin Transl Sci. 2021 Nov 19; doi: 10.1111/cts.13181. Epub 2021 Nov 19.

The majority of disease modifying therapies for multiple sclerosis (MS) reduce inflammation, but do no't target remyelination. Development of remyelinating therapies will benefit from a method to quantify myelin kinetics in patients with MS. We labeled myelin in vivo...

Hospital-Level Percutaneous Coronary Intervention Performance With Simulated Risk Avoidance.

Journal of the American College of Cardiology

Nathan AS, Manandhar P, Wojdyla D, Nelson A, Fiorilli PN, Waldo S, Yeh RW, Rao SV, Fanaroff AC, Groeneveld PW, Wang TY, Giri J.
PMID: 34823664
J Am Coll Cardiol. 2021 Nov 30;78(22):2213-2217. doi: 10.1016/j.jacc.2021.09.862.

No abstract available.

Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury.

Blood

Poole LG, Kopec AK, Groeneveld DJ, Pant A, Baker KS, Cline-Fedewa HM, Flick MJ, Luyendyk JP.
PMID: 33569603
Blood. 2021 May 06;137(18):2520-2531. doi: 10.1182/blood.2020007415.

Intravascular fibrin clot formation follows a well-ordered series of reactions catalyzed by thrombin cleavage of fibrinogen leading to fibrin polymerization and cross-linking by factor XIIIa (FXIIIa). Extravascular fibrin(ogen) deposits are observed in injured tissues; however, the mechanisms regulating fibrin(ogen)...

Showing 169 to 172 of 172 entries