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Showing 25 to 33 of 33 entries
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Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells.

Frontiers in immunology

Drabek D, Janssens R, de Boer E, Rademaker R, Kloess J, Skehel J, Grosveld F.
PMID: 28066429
Front Immunol. 2016 Dec 19;7:619. doi: 10.3389/fimmu.2016.00619. eCollection 2016.

Several technologies have been developed to isolate human antibodies against different target antigens as a source of potential therapeutics, including hybridoma technology, phage and yeast display systems. For conventional antibodies, this involves either random pairing of VH and variable...

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Drabek D, Janssens R, de Boer E, et al. Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells. Front Immunol. 2016;7:619doi: 10.3389/fimmu.2016.00619.
Drabek, D., Janssens, R., de Boer, E., Rademaker, R., Kloess, J., Skehel, J., & Grosveld, F. (2016). Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells. Frontiers in immunology, 7619. https://doi.org/10.3389/fimmu.2016.00619
Drabek, Dubravka, et al. "Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells." Frontiers in immunology vol. 7 (2016): 619. doi: https://doi.org/10.3389/fimmu.2016.00619
Drabek D, Janssens R, de Boer E, Rademaker R, Kloess J, Skehel J, Grosveld F. Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells. Front Immunol. 2016 Dec 19;7:619. doi: 10.3389/fimmu.2016.00619. eCollection 2016. PMID: 28066429; PMCID: PMC5165034.
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Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis.

JCI insight

Fukuda Y, Wang Y, Lian S, Lynch J, Nagai S, Fanshawe B, Kandilci A, Janke LJ, Neale G, Fan Y, Sorrentino BP, Roussel MF, Grosveld G, Schuetz JD.
PMID: 28768907
JCI Insight. 2017 Aug 03;2(15). doi: 10.1172/jci.insight.92409. eCollection 2017 Aug 03.

The increased heme biosynthesis long observed in leukemia was previously of unknown significance. Heme, synthesized from porphyrin precursors, plays a central role in oxygen metabolism and mitochondrial function, yet little is known about its role in leukemogenesis. Here, we...

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Fukuda Y, Wang Y, Lian S, et al. Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. JCI Insight. 2017;2(15)doi: 10.1172/jci.insight.92409.
Fukuda, Y., Wang, Y., Lian, S., Lynch, J., Nagai, S., Fanshawe, B., Kandilci, A., Janke, L. J., Neale, G., Fan, Y., Sorrentino, B. P., Roussel, M. F., Grosveld, G., & Schuetz, J. D. (2017). Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. JCI insight, 2(15), . https://doi.org/10.1172/jci.insight.92409
Fukuda, Yu, et al. "Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis." JCI insight vol. 2,15 (2017). doi: https://doi.org/10.1172/jci.insight.92409
Fukuda Y, Wang Y, Lian S, Lynch J, Nagai S, Fanshawe B, Kandilci A, Janke LJ, Neale G, Fan Y, Sorrentino BP, Roussel MF, Grosveld G, Schuetz JD. Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. JCI Insight. 2017 Aug 03;2(15). doi: 10.1172/jci.insight.92409. eCollection 2017 Aug 03. PMID: 28768907; PMCID: PMC5543914.
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Magnetic-related States and Order Parameter Induced in a Conventional Superconductor by Nonmagnetic Chiral Molecules.

Nano letters

Alpern H, Yavilberg K, Dvir T, Sukenik N, Klang M, Yochelis S, Cohen H, Grosfeld E, Steinberg H, Paltiel Y, Millo O.
PMID: 31361954
Nano Lett. 2019 Aug 14;19(8):5167-5175. doi: 10.1021/acs.nanolett.9b01552. Epub 2019 Aug 05.

Hybrid ferromagnetic/superconducting systems are well-known for hosting intriguing phenomena such as emergent triplet superconductivity at their interfaces and the appearance of in-gap, spin-polarized Yu-Shiba-Rusinov (YSR) states bound to magnetic impurities on a superconducting surface. In this work we demonstrate...

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Alpern H, Yavilberg K, Dvir T, et al. Magnetic-related States and Order Parameter Induced in a Conventional Superconductor by Nonmagnetic Chiral Molecules. Nano Lett. 2019;19(8):5167-5175doi: 10.1021/acs.nanolett.9b01552.
Alpern, H., Yavilberg, K., Dvir, T., Sukenik, N., Klang, M., Yochelis, S., Cohen, H., Grosfeld, E., Steinberg, H., Paltiel, Y., & Millo, O. (2019). Magnetic-related States and Order Parameter Induced in a Conventional Superconductor by Nonmagnetic Chiral Molecules. Nano letters, 19(8), 5167-5175. https://doi.org/10.1021/acs.nanolett.9b01552
Alpern, Hen, et al. "Magnetic-related States and Order Parameter Induced in a Conventional Superconductor by Nonmagnetic Chiral Molecules." Nano letters vol. 19,8 (2019): 5167-5175. doi: https://doi.org/10.1021/acs.nanolett.9b01552
Alpern H, Yavilberg K, Dvir T, Sukenik N, Klang M, Yochelis S, Cohen H, Grosfeld E, Steinberg H, Paltiel Y, Millo O. Magnetic-related States and Order Parameter Induced in a Conventional Superconductor by Nonmagnetic Chiral Molecules. Nano Lett. 2019 Aug 14;19(8):5167-5175. doi: 10.1021/acs.nanolett.9b01552. Epub 2019 Aug 05. PMID: 31361954.
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Publisher Correction: A human monoclonal antibody blocking SARS-CoV-2 infection.

Nature communications

Wang C, Li W, Drabek D, Okba NMA, van Haperen R, Osterhaus ADME, van Kuppeveld FJM, Haagmans BL, Grosveld F, Bosch BJ.
PMID: 32409714
Nat Commun. 2020 May 14;11(1):2511. doi: 10.1038/s41467-020-16452-w.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Wang C, Li W, Drabek D, et al. Publisher Correction: A human monoclonal antibody blocking SARS-CoV-2 infection. Nat Commun. 2020;11(1):2511doi: 10.1038/s41467-020-16452-w.
Wang, C., Li, W., Drabek, D., Okba, N. M. A., van Haperen, R., Osterhaus, A. D. M. E., van Kuppeveld, F. J. M., Haagmans, B. L., Grosveld, F., & Bosch, B. J. (2020). Publisher Correction: A human monoclonal antibody blocking SARS-CoV-2 infection. Nature communications, 11(1), 2511. https://doi.org/10.1038/s41467-020-16452-w
Wang, Chunyan, et al. "Publisher Correction: A human monoclonal antibody blocking SARS-CoV-2 infection." Nature communications vol. 11,1 (2020): 2511. doi: https://doi.org/10.1038/s41467-020-16452-w
Wang C, Li W, Drabek D, Okba NMA, van Haperen R, Osterhaus ADME, van Kuppeveld FJM, Haagmans BL, Grosveld F, Bosch BJ. Publisher Correction: A human monoclonal antibody blocking SARS-CoV-2 infection. Nat Commun. 2020 May 14;11(1):2511. doi: 10.1038/s41467-020-16452-w. PMID: 32409714; PMCID: PMC7224291.
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The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes.

Epigenetics & chromatin

Knoch TA, Wachsmuth M, Kepper N, Lesnussa M, Abuseiris A, Ali Imam AM, Kolovos P, Zuin J, Kockx CEM, Brouwer RWW, van de Werken HJG, van IJcken WFJ, Wendt KS, Grosveld FG.
PMID: 28035242
Epigenetics Chromatin. 2016 Dec 24;9:58. doi: 10.1186/s13072-016-0089-x. eCollection 2016.

BACKGROUND: The dynamic three-dimensional chromatin architecture of genomes and its co-evolutionary connection to its function-the storage, expression, and replication of genetic information-is still one of the central issues in biology. Here, we describe the much debated 3D architecture of...

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Knoch TA, Wachsmuth M, Kepper N, et al. The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes. Epigenetics Chromatin. 2016;9:58doi: 10.1186/s13072-016-0089-x.
Knoch, T. A., Wachsmuth, M., Kepper, N., Lesnussa, M., Abuseiris, A., Ali Imam, A. M., Kolovos, P., Zuin, J., Kockx, C. E. M., Brouwer, R. W. W., van de Werken, H. J. G., van IJcken, W. F. J., Wendt, K. S., & Grosveld, F. G. (2016). The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes. Epigenetics & chromatin, 958. https://doi.org/10.1186/s13072-016-0089-x
Knoch, Tobias A, et al. "The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes." Epigenetics & chromatin vol. 9 (2016): 58. doi: https://doi.org/10.1186/s13072-016-0089-x
Knoch TA, Wachsmuth M, Kepper N, Lesnussa M, Abuseiris A, Ali Imam AM, Kolovos P, Zuin J, Kockx CEM, Brouwer RWW, van de Werken HJG, van IJcken WFJ, Wendt KS, Grosveld FG. The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes. Epigenetics Chromatin. 2016 Dec 24;9:58. doi: 10.1186/s13072-016-0089-x. eCollection 2016. PMID: 28035242; PMCID: PMC5192698.
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Parent-Child Dyadic Coping and Quality of Life in Chronically Diseased Children.

Frontiers in psychology

Nap-van der Vlist MM, van der Wal RC, Grosfeld E, van de Putte EM, Dalmeijer GW, Grootenhuis MA, van der Ent CK, van den Heuvel-Eibrink MM, Swart JF, Bodenmann G, Finkenauer C, Nijhof SL.
PMID: 34393938
Front Psychol. 2021 Jul 28;12:701540. doi: 10.3389/fpsyg.2021.701540. eCollection 2021.

Different forms of dyadic coping are associated with positive outcomes in partner relationships, yet little is known about dyadic coping in parent-child relationships. The current research explored the association between parent-child dyadic coping and children's quality of life in...

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Nap-van der Vlist MM, van der Wal RC, Grosfeld E, et al. Parent-Child Dyadic Coping and Quality of Life in Chronically Diseased Children. Front Psychol. 2021;12:701540doi: 10.3389/fpsyg.2021.701540.
Nap-van der Vlist, M. M., van der Wal, R. C., Grosfeld, E., van de Putte, E. M., Dalmeijer, G. W., Grootenhuis, M. A., van der Ent, C. K., van den Heuvel-Eibrink, M. M., Swart, J. F., Bodenmann, G., Finkenauer, C., & Nijhof, S. L. (2021). Parent-Child Dyadic Coping and Quality of Life in Chronically Diseased Children. Frontiers in psychology, 12701540. https://doi.org/10.3389/fpsyg.2021.701540
Nap-van der Vlist, Merel M, et al. "Parent-Child Dyadic Coping and Quality of Life in Chronically Diseased Children." Frontiers in psychology vol. 12 (2021): 701540. doi: https://doi.org/10.3389/fpsyg.2021.701540
Nap-van der Vlist MM, van der Wal RC, Grosfeld E, van de Putte EM, Dalmeijer GW, Grootenhuis MA, van der Ent CK, van den Heuvel-Eibrink MM, Swart JF, Bodenmann G, Finkenauer C, Nijhof SL. Parent-Child Dyadic Coping and Quality of Life in Chronically Diseased Children. Front Psychol. 2021 Jul 28;12:701540. doi: 10.3389/fpsyg.2021.701540. eCollection 2021. PMID: 34393938; PMCID: PMC8355494.
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Lysosomes and Cancer Progression: A Malignant Liaison.

Frontiers in cell and developmental biology

Machado ER, Annunziata I, van de Vlekkert D, Grosveld GC, d'Azzo A.
PMID: 33718382
Front Cell Dev Biol. 2021 Feb 26;9:642494. doi: 10.3389/fcell.2021.642494. eCollection 2021.

During primary tumorigenesis isolated cancer cells may undergo genetic or epigenetic changes that render them responsive to additional intrinsic or extrinsic cues, so that they enter a transitional state and eventually acquire an aggressive, metastatic phenotype. Among these changes...

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Machado ER, Annunziata I, van de Vlekkert D, et al. Lysosomes and Cancer Progression: A Malignant Liaison. Front Cell Dev Biol. 2021;9:642494doi: 10.3389/fcell.2021.642494.
Machado, E. R., Annunziata, I., van de Vlekkert, D., Grosveld, G. C., & d'Azzo, A. (2021). Lysosomes and Cancer Progression: A Malignant Liaison. Frontiers in cell and developmental biology, 9642494. https://doi.org/10.3389/fcell.2021.642494
Machado, Eda R, et al. "Lysosomes and Cancer Progression: A Malignant Liaison." Frontiers in cell and developmental biology vol. 9 (2021): 642494. doi: https://doi.org/10.3389/fcell.2021.642494
Machado ER, Annunziata I, van de Vlekkert D, Grosveld GC, d'Azzo A. Lysosomes and Cancer Progression: A Malignant Liaison. Front Cell Dev Biol. 2021 Feb 26;9:642494. doi: 10.3389/fcell.2021.642494. eCollection 2021. PMID: 33718382; PMCID: PMC7952443.
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PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells.

Biomaterials

Cruz LJ, van Dijk T, Vepris O, Li TMWY, Schomann T, Baldazzi F, Kurita R, Nakamura Y, Grosveld F, Philipsen S, Eich C.
PMID: 33321292
Biomaterials. 2021 Jan;268:120580. doi: 10.1016/j.biomaterials.2020.120580. Epub 2020 Dec 07.

Ex vivo gene editing of CD34

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Cruz LJ, van Dijk T, Vepris O, et al. PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells. Biomaterials. 2020;268:120580doi: 10.1016/j.biomaterials.2020.120580.
Cruz, L. J., van Dijk, T., Vepris, O., Li, T. M. W. Y., Schomann, T., Baldazzi, F., Kurita, R., Nakamura, Y., Grosveld, F., Philipsen, S., & Eich, C. (2021). PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells. Biomaterials, 268120580. https://doi.org/10.1016/j.biomaterials.2020.120580
Cruz, Luis J, et al. "PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells." Biomaterials vol. 268 (2021): 120580. doi: https://doi.org/10.1016/j.biomaterials.2020.120580
Cruz LJ, van Dijk T, Vepris O, Li TMWY, Schomann T, Baldazzi F, Kurita R, Nakamura Y, Grosveld F, Philipsen S, Eich C. PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells. Biomaterials. 2021 Jan;268:120580. doi: 10.1016/j.biomaterials.2020.120580. Epub 2020 Dec 07. PMID: 33321292.
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Handshape monitoring: Evaluation of linguistic and perceptual factors in the processing of American Sign Language.

Language and cognitive processes

Grosvald M, Lachaud C, Corina D.
PMID: 22822282
Lang Cogn Process. 2012 Jan 01;27(1):117-141. doi: 10.1080/01690965.2010.549667. Epub 2011 Nov 18.

We investigated the relevance of linguistic and perceptual factors to sign processing by comparing hearing individuals and deaf signers as they performed a handshape monitoring task, a sign-language analogue to the phoneme-monitoring paradigms used in many spoken-language studies. Each...

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Grosvald M, Lachaud C, Corina D. Handshape monitoring: Evaluation of linguistic and perceptual factors in the processing of American Sign Language. Lang Cogn Process. 2011;27(1):117-141doi: 10.1080/01690965.2010.549667.
Grosvald, M., Lachaud, C., & Corina, D. (2012). Handshape monitoring: Evaluation of linguistic and perceptual factors in the processing of American Sign Language. Language and cognitive processes, 27(1), 117-141. https://doi.org/10.1080/01690965.2010.549667
Grosvald, Michael, et al. "Handshape monitoring: Evaluation of linguistic and perceptual factors in the processing of American Sign Language." Language and cognitive processes vol. 27,1 (2012): 117-141. doi: https://doi.org/10.1080/01690965.2010.549667
Grosvald M, Lachaud C, Corina D. Handshape monitoring: Evaluation of linguistic and perceptual factors in the processing of American Sign Language. Lang Cogn Process. 2012 Jan 01;27(1):117-141. doi: 10.1080/01690965.2010.549667. Epub 2011 Nov 18. PMID: 22822282; PMCID: PMC3399660.
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Showing 25 to 33 of 33 entries