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Showing 13 to 24 of 133 entries
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Mobilization of Hematopoietic Stem Cells into Peripheral Blood for Autologous Transplantation Seems Less Efficacious in Poor Mobilizers with the Use of a Biosimilar of Filgrastim and Plerixafor: A Retrospective Comparative Analysis.

Oncology and therapy

Parody R, Sánchez-Ortega I, Ferrá C, Guardia R, Talarn C, Encuentra M, Fort E, López D, Morgades M, Alonso E, Ortega S, Sarrá J, Gallardo D, Ribera JM, Sureda A.
PMID: 32700041
Oncol Ther. 2020 Dec;8(2):311-324. doi: 10.1007/s40487-020-00115-3. Epub 2020 May 14.

INTRODUCTION: Biosimilars of granulocyte colony-stimulating factors (G-CSF) have shown similar efficacy to originator filgrastim (Neupogen® [NEU]; Amgen Inc.) as prophylaxis in neutropenia and in the mobilization of stem cells in patients receiving combination chemotherapy with G-CSF.METHODS: This was a...

Tin Diselenide Molecular Precursor for Solution-Processable Thermoelectric Materials.

Angewandte Chemie (International ed. in English)

Zhang Y, Liu Y, Lim KH, Xing C, Li M, Zhang T, Tang P, Arbiol J, Llorca J, Ng KM, Ibáñez M, Guardia P, Prato M, Cadavid D, Cabot A.
PMID: 30398301
Angew Chem Int Ed Engl. 2018 Dec 21;57(52):17063-17068. doi: 10.1002/anie.201809847. Epub 2018 Nov 25.

In the present work, we detail a fast and simple solution-based method to synthesize hexagonal SnSe

Free Thyroxine Concentrations Moderate the Response to a Cognitive Remediation Therapy in People With Early Psychosis: A Pilot Randomized Clinical Trial.

Frontiers in psychiatry

Estrada F, Crosas JM, Ahuir M, Pérez-Muñoz S, Zabala W, Aguayo R, Barbero JD, Montalvo I, Tost M, Llauradó L, Guardia A, Palao D, Monreal JA, Labad J.
PMID: 32733292
Front Psychiatry. 2020 Jul 07;11:636. doi: 10.3389/fpsyt.2020.00636. eCollection 2020.

INTRODUCTION: Cognitive deficits are a cause of functional disability in psychotic disorders. Cognitive remediation therapy (CRT) might be applied to improve these deficits. We conducted a pilot study to explore whether thyroid hormones might predict the response to CRT...

One pot synthesis of monodisperse water soluble iron oxide nanocrystals with high values of the specific absorption rate.

Journal of materials chemistry. B

Guardia P, Riedinger A, Nitti S, Pugliese G, Marras S, Genovese A, Materia ME, Lefevre C, Manna L, Pellegrino T.
PMID: 32261543
J Mater Chem B. 2014 Jul 28;2(28):4426-4434. doi: 10.1039/c4tb00061g. Epub 2014 Jun 13.

We report a highly reproducible route to synthesize iron oxide nanoparticles (IONPs) with control over size and shape and with size dispersions around 10%. By tuning the relative ratio of squalane to dibenzyl ether, which were used as solvents...

Distance sampling surveys reveal 17 million vertebrates directly killed by the 2020's wildfires in the Pantanal, Brazil.

Scientific reports

Tomas WM, Berlinck CN, Chiaravalloti RM, Faggioni GP, Strüssmann C, Libonati R, Abrahão CR, do Valle Alvarenga G, de Faria Bacellar AE, de Queiroz Batista FR, Bornato TS, Camilo AR, Castedo J, Fernando AME, de Freitas GO, Garcia CM, Gonçalves HS, de Freitas Guilherme MB, Layme VMG, Lustosa APG, De Oliveira AC, da Rosa Oliveira M, de Matos Martins Pereira A, Rodrigues JA, Semedo TBF, de Souza RAD, Tortato FR, Viana DFP, Vicente-Silva L, Morato R.
PMID: 34916541
Sci Rep. 2021 Dec 16;11(1):23547. doi: 10.1038/s41598-021-02844-5.

Anthropogenic factors have significantly influenced the frequency, duration, and intensity of meteorological drought in many regions of the globe, and the increased frequency of wildfires is among the most visible consequences of human-induced climate change. Despite the fire role...

Insulin-degrading enzyme: an ally against metabolic and neurodegenerative diseases.

The Journal of pathology

Sousa L, Guarda M, Meneses MJ, Macedo MP, Vicente Miranda H.
PMID: 34396529
J Pathol. 2021 Dec;255(4):346-361. doi: 10.1002/path.5777. Epub 2021 Sep 17.

Insulin-degrading enzyme (IDE) function goes far beyond its known proteolytic role as a regulator of insulin levels. IDE has a wide substrate promiscuity, degrading several proteins such as amyloid-β peptide, glucagon, islet amyloid polypeptide (IAPP), and insulin-like growth factors,...

Preclinical and Clinical Characterization of Fibroblast-derived Neuregulin-1 on Trastuzumab and Pertuzumab Activity in HER2-positive Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Guardia C, Bianchini G, Arpí-LLucià O, Menendez S, Casadevall D, Galbardi B, Dugo M, Servitja S, Montero JC, Soria-Jiménez L, Sabbaghi M, Peña R, Madoz-Gúrpide J, Lloveras B, Lluch A, Eroles P, Arribas J, Pandiella A, Gianni L, Rojo F, Rovira A, Albanell J.
PMID: 34385295
Clin Cancer Res. 2021 Sep 15;27(18):5096-5108. doi: 10.1158/1078-0432.CCR-20-2915. Epub 2021 Aug 12.

PURPOSE: To characterize expression of neuregulin-1 (NRG1), an HER3 ligand, in HER2-positive breast cancer and its relation with the efficacy of trastuzumab with or without pertuzumab.EXPERIMENTAL DESIGN: Characterization of NRG1 expression in tumor cell lines, in tumor specimens, and...

Combined Effect of Temperature and Oil and Salt Contents on the Variation of Dielectric Properties of a Tomato-Based Homogenate.

Foods (Basel, Switzerland)

Abea A, Gou P, Guardia MD, Bañon S, Muñoz I.
PMID: 34945675
Foods. 2021 Dec 16;10(12). doi: 10.3390/foods10123124.

Tomato-based processed foods are a key component of modern diets, usually combined with salt and olive oil in different ratios. For the design of radiofrequency (RF) and microwave (MW) heating processes of tomato-based products, it is of importance to...

Insulin-degrading enzyme: an ally against metabolic and neurodegenerative diseases.

The Journal of pathology

Sousa L, Guarda M, Meneses MJ, Macedo MP, Vicente Miranda H.
PMID: 34396529
J Pathol. 2021 Dec;255(4):346-361. doi: 10.1002/path.5777. Epub 2021 Sep 17.

Insulin-degrading enzyme (IDE) function goes far beyond its known proteolytic role as a regulator of insulin levels. IDE has a wide substrate promiscuity, degrading several proteins such as amyloid-β peptide, glucagon, islet amyloid polypeptide (IAPP), and insulin-like growth factors,...

On the Different Faces of the Supercritical Phase of Water at a Near-Critical Temperature: Pressure-Induced Structural Transitions Ranging from a Gaslike Fluid to a Plastic Crystal Polymorph.

The journal of physical chemistry. B

Skarmoutsos I, Henao A, Guardia E, Samios J.
PMID: 34491748
J Phys Chem B. 2021 Sep 16;125(36):10260-10272. doi: 10.1021/acs.jpcb.1c05053. Epub 2021 Sep 07.

The present study reports a systematic analysis of a wide variety of structural, thermodynamic, and dynamic properties of supercritical water along the near-critical isotherm of

Solvation structure and dynamics of the dimethylammonium cation diluted in liquid water: A molecular dynamics approach.

The Journal of chemical physics

Skarmoutsos I, Guardia E.
PMID: 32571039
J Chem Phys. 2020 Jun 21;152(23):234501. doi: 10.1063/5.0004204.

Classical molecular dynamics simulation techniques were employed to investigate the local solvation structure and related dynamics of the dimethylammonium cation diluted in liquid water at ambient conditions. The translational and orientational order around the dimethylammonium cation was investigated in...

Photodehydrogenation of Ethanol over Cu.

Nanomaterials (Basel, Switzerland)

Xing C, Zhang Y, Liu Y, Wang X, Li J, Martínez-Alanis PR, Spadaro MC, Guardia P, Arbiol J, Llorca J, Cabot A.
PMID: 34070566
Nanomaterials (Basel). 2021 May 25;11(6). doi: 10.3390/nano11061399.

The photodehydrogenation of ethanol is a sustainable and potentially cost-effective strategy to produce hydrogen and acetaldehyde from renewable resources. The optimization of this process requires the use of highly active, stable and selective photocatalytic materials based on abundant elements...

Showing 13 to 24 of 133 entries