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Showing 25 to 36 of 133 entries
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Distance sampling surveys reveal 17 million vertebrates directly killed by the 2020's wildfires in the Pantanal, Brazil.

Scientific reports

Tomas WM, Berlinck CN, Chiaravalloti RM, Faggioni GP, Strüssmann C, Libonati R, Abrahão CR, do Valle Alvarenga G, de Faria Bacellar AE, de Queiroz Batista FR, Bornato TS, Camilo AR, Castedo J, Fernando AME, de Freitas GO, Garcia CM, Gonçalves HS, de Freitas Guilherme MB, Layme VMG, Lustosa APG, De Oliveira AC, da Rosa Oliveira M, de Matos Martins Pereira A, Rodrigues JA, Semedo TBF, de Souza RAD, Tortato FR, Viana DFP, Vicente-Silva L, Morato R.
PMID: 34916541
Sci Rep. 2021 Dec 16;11(1):23547. doi: 10.1038/s41598-021-02844-5.

Anthropogenic factors have significantly influenced the frequency, duration, and intensity of meteorological drought in many regions of the globe, and the increased frequency of wildfires is among the most visible consequences of human-induced climate change. Despite the fire role...

The falling teacup: a curious stroke case.

Arquivos de neuro-psiquiatria

Rachão A, Geraldes T, Guarda C.
PMID: 34932645
Arq Neuropsiquiatr. 2021 Dec 17; doi: 10.1590/0004-282X-ANP-2021-0163. Epub 2021 Dec 17.

No abstract available.

Immune microenvironment characterisation and dynamics during anti-HER2-based neoadjuvant treatment in HER2-positive breast cancer.

NPJ precision oncology

Griguolo G, Serna G, Pascual T, Fasani R, Guardia X, Chic N, Paré L, Pernas S, Muñoz M, Oliveira M, Vidal M, Llombart-Cussac A, Cortés J, Galván P, Bermejo B, Martínez N, López R, Morales S, Garau I, Manso L, Alarcón J, Martínez E, Villagrasa P, Prat A, Nuciforo P.
PMID: 33742063
NPJ Precis Oncol. 2021 Mar 19;5(1):23. doi: 10.1038/s41698-021-00163-6.

Despite their recognised role in HER2-positive (HER2+) breast cancer (BC), the composition, localisation and functional orientation of immune cells within tumour microenvironment, as well as its dynamics during anti-HER2 treatment, is largely unknown. We here investigate changes in tumour-immune...

Endothelial Nitric Oxide Synthase (-786T>C) and Endothelin-1 (5665G>T) Gene Polymorphisms as Vascular Dysfunction Risk Factors in Sickle Cell Anemia.

Gene regulation and systems biology

Vilas-Boas W, Figueiredo CV, Pitanga TN, Carvalho MO, Santiago RP, Santana SS, Guarda CC, Zanette AM, Cerqueira BA, Gonçalves MS.
PMID: 27486304
Gene Regul Syst Bio. 2016 Jul 28;10:67-72. doi: 10.4137/GRSB.S38276. eCollection 2016.

Sickle cell anemia (SCA) patients have vascular complications, and polymorphisms in endothelin-1 (ET-1) and endothelial nitric oxide synthase (eNOS) genes were associated with ET-1 and nitric oxide disturbance. We investigate the association of ET-1 5665G>T and eNOS -786T>C polymorphisms...

Appraisal and coping as mediators of the effects of cumulative risk on preadolescent adjustment.

Journal of child and family studies

Thompson SF, Lengua LJ, Garcia CM.
PMID: 27110087
J Child Fam Stud. 2016 May 01;25(5):1416-1429. doi: 10.1007/s10826-015-0338-9. Epub 2015 Dec 09.

This study examined the concurrent and longitudinal relations among cumulative risk, appraisal, coping, and adjustment. Longitudinal path models were tested in a community sample of 316 children in preadolescence to examine hypotheses that threat appraisal and avoidant coping mediate...

A survey study examining the motivations, concerns, and perspectives of medical students engaging in neurosurgical research.

Surgical neurology international

Barrios-Anderson A, Wu E, Liu DD, Snead J, Lee DJ, Robbins J, Aguirre J, Tang O, Garcia CM, Pucci F, Anderson MN, Syed S, Shaaya E, Gokaslan ZL.
PMID: 34754540
Surg Neurol Int. 2021 Sep 30;12:490. doi: 10.25259/SNI_742_2021. eCollection 2021.

BACKGROUND: In a competitive landscape for neurosurgical residency admission, research productivity is increasingly important. Medical school applicants to neurosurgery report high numbers of "scholarly products" as published by the National Residency Match Program. Despite increased student involvement in research...

The autophagy protein ATG9A enables lipid mobilization from lipid droplets.

Nature communications

Mailler E, Guardia CM, Bai X, Jarnik M, Williamson CD, Li Y, Maio N, Golden A, Bonifacino JS.
PMID: 34799570
Nat Commun. 2021 Nov 19;12(1):6750. doi: 10.1038/s41467-021-26999-x.

The multispanning membrane protein ATG9A is a scramblase that flips phospholipids between the two membrane leaflets, thus contributing to the expansion of the phagophore membrane in the early stages of autophagy. Herein, we show that depletion of ATG9A does...

Effect of lysed and non-lysed sickle red cells on the activation of NLRP3 inflammasome and LTB4 production by mononuclear cells.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Pitanga TN, Santana SS, Zanette DL, Guarda CC, Santiago RP, Maffili VV, Lima JB, Carvalho GQ, Filho JR, Ferreira JRD, Aleluia MM, Nascimento VML, Carvalho MOS, Lyra IM, Borges VM, Oliveira RR, Goncalves MS.
PMID: 34196737
Inflamm Res. 2021 Jul;70(7):823-834. doi: 10.1007/s00011-021-01461-2. Epub 2021 Jul 01.

OBJECTIVE AND DESIGN: This study tested the hypothesis that sickle red blood cell (SS-RBC) can induce inflammasome NLRP3 components gene expression in peripheral blood mononuclear cells (PBMCs) as well as interleukin-1β (IL-1β) and leukotriene B4 (LTB4) production. Additionally, we...

RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery.

Molecular biology of the cell

Guardia CM, Jain A, Mattera R, Friefeld A, Li Y, Bonifacino JS.
PMID: 34432492
Mol Biol Cell. 2021 Nov 01;32(21):ar25. doi: 10.1091/mbc.E21-06-0295. Epub 2021 Aug 25.

Autophagy-related protein 9 (ATG9) is a transmembrane protein component of the autophagy machinery that cycles between the

Chemically exfoliated MoS₂ nanosheets as an efficient catalyst for reduction reactions in the aqueous phase.

ACS applied materials & interfaces

Guardia L, Paredes JI, Munuera JM, Villar-Rodil S, Ayán-Varela M, Martínez-Alonso A, Tascón JM.
PMID: 25405770
ACS Appl Mater Interfaces. 2014 Dec 10;6(23):21702-10. doi: 10.1021/am506922q. Epub 2014 Nov 26.

Chemically exfoliated MoS2 (ce-MoS2) nanosheets that incorporate a large fraction of metallic 1T phase have been recently shown to possess a high electrocatalytic activity in the hydrogen evolution reaction, but the potential of this two-dimensional material as a catalyst...

Giant obscurin regulates migration and metastasis via RhoA-dependent cytoskeletal remodeling in pancreatic cancer.

Cancer letters

Tuntithavornwat S, Shea DJ, Wong BS, Guardia T, Lee SJ, Yankaskas CL, Zheng L, Kontrogianni-Konstantopoulos A, Konstantopoulos K.
PMID: 34826548
Cancer Lett. 2022 Feb 01;526:155-167. doi: 10.1016/j.canlet.2021.11.016. Epub 2021 Nov 23.

Obscurins, encoded by the OBSCN gene, are giant cytoskeletal proteins with structural and regulatory roles. Large scale omics analyses reveal that OBSCN is highly mutated across different types of cancer, exhibiting a 5-8% mutation frequency in pancreatic cancer. Yet,...

A Direct Z-Scheme for the Photocatalytic Hydrogen Production from a Water Ethanol Mixture on CoTiO.

ACS applied materials & interfaces

Xing C, Liu Y, Zhang Y, Wang X, Guardia P, Yao L, Han X, Zhang T, Arbiol J, Soler L, Chen Y, Sivula K, Guijarro N, Cabot A, Llorca J.
PMID: 33386057
ACS Appl Mater Interfaces. 2021 Jan 13;13(1):449-457. doi: 10.1021/acsami.0c17004. Epub 2021 Jan 01.

Photocatalytic H

Showing 25 to 36 of 133 entries