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Heating it up: Oncolytic viruses make tumors 'hot' and suitable for checkpoint blockade immunotherapies.

Oncoimmunology

Gujar S, Pol JG, Kroemer G.
PMID: 30221036
Oncoimmunology. 2018 Mar 13;7(8):e1442169. doi: 10.1080/2162402X.2018.1442169. eCollection 2018.

Immune checkpoint blockade is less efficient in patients bearing immunologically 'cold' tumors. Oncolytic viruses, which were originally discovered for their ability to preferentially kill malignant cells, can recondition the tumor microenvironment. Supporting this hypothesis, two new studies published in

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Gujar S, Pol JG, Kroemer G. Heating it up: Oncolytic viruses make tumors 'hot' and suitable for checkpoint blockade immunotherapies. Oncoimmunology. 2018;7(8):e1442169doi: 10.1080/2162402X.2018.1442169.
Gujar, S., Pol, J. G., & Kroemer, G. (2018). Heating it up: Oncolytic viruses make tumors 'hot' and suitable for checkpoint blockade immunotherapies. Oncoimmunology, 7(8), e1442169. https://doi.org/10.1080/2162402X.2018.1442169
Gujar, Shashi, et al. "Heating it up: Oncolytic viruses make tumors 'hot' and suitable for checkpoint blockade immunotherapies." Oncoimmunology vol. 7,8 (2018): e1442169. doi: https://doi.org/10.1080/2162402X.2018.1442169
Gujar S, Pol JG, Kroemer G. Heating it up: Oncolytic viruses make tumors 'hot' and suitable for checkpoint blockade immunotherapies. Oncoimmunology. 2018 Mar 13;7(8):e1442169. doi: 10.1080/2162402X.2018.1442169. eCollection 2018. PMID: 30221036; PMCID: PMC6136862.
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Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis.

Stem cells international

Vasyliev RG, Gubar OS, Gordiienko IM, Litvinova LS, Rodnichenko AE, Shupletsova VV, Zlatska AV, Yurova KA, Todosenko NM, Khadzhynova VE, Shulha MV, Novikova SN, Zubov DO.
PMID: 30915126
Stem Cells Int. 2019 Feb 19;2019:9640790. doi: 10.1155/2019/9640790. eCollection 2019.

INTRODUCTION: The adult neural crest-derived stem cells (NCSCs) have significant perspectives for use in regenerative medicine. The most attractive sources for adult NCSC isolation are the hair follicles (HF) and skin dermis (SD) because of easy access and minimally...

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Vasyliev RG, Gubar OS, Gordiienko IM, et al. Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis. Stem Cells Int. 2019;2019:9640790doi: 10.1155/2019/9640790.
Vasyliev, R. G., Gubar, O. S., Gordiienko, I. M., Litvinova, L. S., Rodnichenko, A. E., Shupletsova, V. V., Zlatska, A. V., Yurova, K. A., Todosenko, N. M., Khadzhynova, V. E., Shulha, M. V., Novikova, S. N., & Zubov, D. O. (2019). Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis. Stem cells international, 20199640790. https://doi.org/10.1155/2019/9640790
Vasyliev, Roman G, et al. "Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis." Stem cells international vol. 2019 (2019): 9640790. doi: https://doi.org/10.1155/2019/9640790
Vasyliev RG, Gubar OS, Gordiienko IM, Litvinova LS, Rodnichenko AE, Shupletsova VV, Zlatska AV, Yurova KA, Todosenko NM, Khadzhynova VE, Shulha MV, Novikova SN, Zubov DO. Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis. Stem Cells Int. 2019 Feb 19;2019:9640790. doi: 10.1155/2019/9640790. eCollection 2019. PMID: 30915126; PMCID: PMC6399535.
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A Selective Turn off Fluorescence Sensor Based on Propranolol-SDS Assemblies for Fe.

Journal of fluorescence

Gujar V, Sangale V, Ottoor D.
PMID: 30361859
J Fluoresc. 2019 Jan;29(1):91-100. doi: 10.1007/s10895-018-2313-5. Epub 2018 Oct 25.

A fluorophore modulation with sodium dodecyl sulphate (SDS) assemblies for the selective and sensitive sensing of Fe

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Gujar V, Sangale V, Ottoor D. A Selective Turn off Fluorescence Sensor Based on Propranolol-SDS Assemblies for Fe. J Fluoresc. 2018;29(1):91-100doi: 10.1007/s10895-018-2313-5.
Gujar, V., Sangale, V., & Ottoor, D. (2019). A Selective Turn off Fluorescence Sensor Based on Propranolol-SDS Assemblies for Fe. Journal of fluorescence, 29(1), 91-100. https://doi.org/10.1007/s10895-018-2313-5
Gujar, Varsha, et al. "A Selective Turn off Fluorescence Sensor Based on Propranolol-SDS Assemblies for Fe." Journal of fluorescence vol. 29,1 (2019): 91-100. doi: https://doi.org/10.1007/s10895-018-2313-5
Gujar V, Sangale V, Ottoor D. A Selective Turn off Fluorescence Sensor Based on Propranolol-SDS Assemblies for Fe. J Fluoresc. 2019 Jan;29(1):91-100. doi: 10.1007/s10895-018-2313-5. Epub 2018 Oct 25. PMID: 30361859.
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Optimization of submerged .

Food science and biotechnology

Naili B, Sahnoun M, Bejar S, Kammoun R.
PMID: 30263256
Food Sci Biotechnol. 2016 Feb 29;25(1):185-192. doi: 10.1007/s10068-016-0028-4. eCollection 2016.

Use of 4 agro-industrial by products and organic materials as nitrogen sources for production of

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Naili B, Sahnoun M, Bejar S, et al. Optimization of submerged . Food Sci Biotechnol. 2016;25(1):185-192doi: 10.1007/s10068-016-0028-4.
Naili, B., Sahnoun, M., Bejar, S., & Kammoun, R. (2016). Optimization of submerged . Food science and biotechnology, 25(1), 185-192. https://doi.org/10.1007/s10068-016-0028-4
Naili, Belgacem, et al. "Optimization of submerged ." Food science and biotechnology vol. 25,1 (2016): 185-192. doi: https://doi.org/10.1007/s10068-016-0028-4
Naili B, Sahnoun M, Bejar S, Kammoun R. Optimization of submerged . Food Sci Biotechnol. 2016 Feb 29;25(1):185-192. doi: 10.1007/s10068-016-0028-4. eCollection 2016. PMID: 30263256; PMCID: PMC6049366.
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A Large PROP1 Gene Deletion in a Turkish Pedigree.

Case reports in endocrinology

Gorar S, Turkkahraman D, Yararbas K.
PMID: 30112224
Case Rep Endocrinol. 2018 Mar 14;2018:2403430. doi: 10.1155/2018/2403430. eCollection 2018.

Pituitary-specific paired-like homeodomain transcription factor, PROP1, is associated with multiple pituitary hormone deficiency. Alteration of the gene encoding the PROP1 may affect somatotropes, thyrotropes, and lactotropes, as well as gonadotropes and corticotropes. We performed genetic analysis of PROP1 gene...

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Gorar S, Turkkahraman D, Yararbas K. A Large PROP1 Gene Deletion in a Turkish Pedigree. Case Rep Endocrinol. 2018;2018:2403430doi: 10.1155/2018/2403430.
Gorar, S., Turkkahraman, D., & Yararbas, K. (2018). A Large PROP1 Gene Deletion in a Turkish Pedigree. Case reports in endocrinology, 20182403430. https://doi.org/10.1155/2018/2403430
Gorar, Suheyla, et al. "A Large PROP1 Gene Deletion in a Turkish Pedigree." Case reports in endocrinology vol. 2018 (2018): 2403430. doi: https://doi.org/10.1155/2018/2403430
Gorar S, Turkkahraman D, Yararbas K. A Large PROP1 Gene Deletion in a Turkish Pedigree. Case Rep Endocrinol. 2018 Mar 14;2018:2403430. doi: 10.1155/2018/2403430. eCollection 2018. PMID: 30112224; PMCID: PMC6077661.
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Ethical issues in conducting international research studies.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Geller S, Naik V, Patel A, Goudar S, Edlavitch S, Kodkany B, Derman R.
PMID: 29644689
Int J Gynaecol Obstet. 2006 Nov;94:S129-S130. doi: 10.1016/S0020-7292(06)60008-8.

No abstract available.

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Geller S, Naik V, Patel A, et al. Ethical issues in conducting international research studies. Int J Gynaecol Obstet. 2006;94:S129-S130doi: 10.1016/S0020-7292(06)60008-8.
Geller, S., Naik, V., Patel, A., Goudar, S., Edlavitch, S., Kodkany, B., & Derman, R. (2006). Ethical issues in conducting international research studies. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 94S129-S130. https://doi.org/10.1016/S0020-7292(06)60008-8
Geller, Stacie, et al. "Ethical issues in conducting international research studies." International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics vol. 94 (2006): S129-S130. doi: https://doi.org/10.1016/S0020-7292(06)60008-8
Geller S, Naik V, Patel A, Goudar S, Edlavitch S, Kodkany B, Derman R. Ethical issues in conducting international research studies. Int J Gynaecol Obstet. 2006 Nov;94:S129-S130. doi: 10.1016/S0020-7292(06)60008-8. PMID: 29644689.
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Advanced heart failure with reduced ejection fraction.

Proceedings (Baylor University. Medical Center)

Hicks A, Velazco JF, Gohar S, Seliem A, Hall SA, Michel JB.
PMID: 32675952
Proc (Bayl Univ Med Cent). 2020 Jun 02;33(3):350-356. doi: 10.1080/08998280.2020.1765663. eCollection 2020 Jul.

Patients suffering advanced heart failure with reduced ejection fraction (HFrEF) account for a large portion of patients admitted to hospitals worldwide. Mortality and 30-day readmission rates for HFrEF are now a focus of value-based payment models, making management of...

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Hicks A, Velazco JF, Gohar S, et al. Advanced heart failure with reduced ejection fraction. Proc (Bayl Univ Med Cent). 2020;33(3):350-356doi: 10.1080/08998280.2020.1765663.
Hicks, A., Velazco, J. F., Gohar, S., Seliem, A., Hall, S. A., & Michel, J. B. (2020). Advanced heart failure with reduced ejection fraction. Proceedings (Baylor University. Medical Center), 33(3), 350-356. https://doi.org/10.1080/08998280.2020.1765663
Hicks, Albert, et al. "Advanced heart failure with reduced ejection fraction." Proceedings (Baylor University. Medical Center) vol. 33,3 (2020): 350-356. doi: https://doi.org/10.1080/08998280.2020.1765663
Hicks A, Velazco JF, Gohar S, Seliem A, Hall SA, Michel JB. Advanced heart failure with reduced ejection fraction. Proc (Bayl Univ Med Cent). 2020 Jun 02;33(3):350-356. doi: 10.1080/08998280.2020.1765663. eCollection 2020 Jul. PMID: 32675952; PMCID: PMC7340451.
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Bioinformatics drives discovery in Biomedicine.

Bioinformation

Gujar R, Panwar B, Dhanda SK.
PMID: 32025155
Bioinformation. 2020 Jan 01;16(1):13-16. doi: 10.6026/97320630016013. eCollection 2020.

Bioinformatics has evolved from providing basic solutions, such as sequence alignment, structure predictions, and phylogenetic analysis to an independent data-driven field. The unprecedented growth of genomic technologies and the enormous data have opened an avenue for bioinformaticians (Bioinformatics professionals)...

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Gujar R, Panwar B, Dhanda SK. Bioinformatics drives discovery in Biomedicine. Bioinformation. 2020;16(1):13-16doi: 10.6026/97320630016013.
Gujar, R., Panwar, B., & Dhanda, S. K. (2020). Bioinformatics drives discovery in Biomedicine. Bioinformation, 16(1), 13-16. https://doi.org/10.6026/97320630016013
Gujar, Ravindra, et al. "Bioinformatics drives discovery in Biomedicine." Bioinformation vol. 16,1 (2020): 13-16. doi: https://doi.org/10.6026/97320630016013
Gujar R, Panwar B, Dhanda SK. Bioinformatics drives discovery in Biomedicine. Bioinformation. 2020 Jan 01;16(1):13-16. doi: 10.6026/97320630016013. eCollection 2020. PMID: 32025155; PMCID: PMC6986933.
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Simultaneous removal of arsenic and toxic metals from contaminated soil: Laboratory development and pilot scale demonstration.

Environmental pollution (Barking, Essex : 1987)

Morales Arteaga JF, Gluhar S, Kaurin A, Lestan D.
PMID: 34890746
Environ Pollut. 2021 Dec 07;294:118656. doi: 10.1016/j.envpol.2021.118656. Epub 2021 Dec 07.

Soil chemistry of toxic metalloids and metals differs, making their simultaneous removal difficult. Soil contaminated with As, Pb, Zn and Cd was washed with oxalic acid, Na-dithionite and EDTA solution. Toxic elements were removed from the washing solution by...

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Morales Arteaga JF, Gluhar S, Kaurin A, et al. Simultaneous removal of arsenic and toxic metals from contaminated soil: Laboratory development and pilot scale demonstration. Environ Pollut. 2021;294:118656doi: 10.1016/j.envpol.2021.118656.
Morales Arteaga, J. F., Gluhar, S., Kaurin, A., & Lestan, D. (2021). Simultaneous removal of arsenic and toxic metals from contaminated soil: Laboratory development and pilot scale demonstration. Environmental pollution (Barking, Essex : 1987), 294118656. https://doi.org/10.1016/j.envpol.2021.118656
Morales Arteaga, Juan Francisco, et al. "Simultaneous removal of arsenic and toxic metals from contaminated soil: Laboratory development and pilot scale demonstration." Environmental pollution (Barking, Essex : 1987) vol. 294 (2021): 118656. doi: https://doi.org/10.1016/j.envpol.2021.118656
Morales Arteaga JF, Gluhar S, Kaurin A, Lestan D. Simultaneous removal of arsenic and toxic metals from contaminated soil: Laboratory development and pilot scale demonstration. Environ Pollut. 2021 Dec 07;294:118656. doi: 10.1016/j.envpol.2021.118656. Epub 2021 Dec 07. PMID: 34890746.
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Desmoplastic Small Round Cell Tumor: A Review of Main Molecular Abnormalities and Emerging Therapy.

Cancers

Mello CA, Campos FAB, Santos TG, Silva MLG, Torrezan GT, Costa FD, Formiga MN, Nicolau U, Nascimento AG, Silva C, Curado MP, Nakagawa SA, Lopes A, Aguiar S.
PMID: 33525546
Cancers (Basel). 2021 Jan 28;13(3). doi: 10.3390/cancers13030498.

Desmoplastic small round cell tumor (DSRCT) is an extremely rare, aggressive sarcoma affecting adolescents and young adults with male predominance. Generally, it originates from the serosal surface of the abdominal cavity. The hallmark characteristic of DSRCT is the EWSR1-WT1...

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Mello CA, Campos FAB, Santos TG, et al. Desmoplastic Small Round Cell Tumor: A Review of Main Molecular Abnormalities and Emerging Therapy. Cancers (Basel). 2021;13(3)doi: 10.3390/cancers13030498.
Mello, C. A., Campos, F. A. B., Santos, T. G., Silva, M. L. G., Torrezan, G. T., Costa, F. D., Formiga, M. N., Nicolau, U., Nascimento, A. G., Silva, C., Curado, M. P., Nakagawa, S. A., Lopes, A., & Aguiar, S. (2021). Desmoplastic Small Round Cell Tumor: A Review of Main Molecular Abnormalities and Emerging Therapy. Cancers, 13(3), . https://doi.org/10.3390/cancers13030498
Mello, Celso Abdon, et al. "Desmoplastic Small Round Cell Tumor: A Review of Main Molecular Abnormalities and Emerging Therapy." Cancers vol. 13,3 (2021). doi: https://doi.org/10.3390/cancers13030498
Mello CA, Campos FAB, Santos TG, Silva MLG, Torrezan GT, Costa FD, Formiga MN, Nicolau U, Nascimento AG, Silva C, Curado MP, Nakagawa SA, Lopes A, Aguiar S. Desmoplastic Small Round Cell Tumor: A Review of Main Molecular Abnormalities and Emerging Therapy. Cancers (Basel). 2021 Jan 28;13(3). doi: 10.3390/cancers13030498. PMID: 33525546; PMCID: PMC7865637.
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Dietary Management of Children With Super-Refractory Status Epilepticus: A Systematic Review and Experience in a Single UK Tertiary Centre.

Frontiers in neurology

Schoeler NE, Simpson Z, Zhou R, Pujar S, Eltze C, Cross JH.
PMID: 33776895
Front Neurol. 2021 Mar 12;12:643105. doi: 10.3389/fneur.2021.643105. eCollection 2021.

Ketogenic diet therapies (KDT) are high-fat, low carbohydrate diets used as an effective treatment option for drug-resistant epilepsy. There is limited research on the efficacy of KDT for super-refractory status epilepticus (SRSE). We systematically review evidence for use of...

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Schoeler NE, Simpson Z, Zhou R, et al. Dietary Management of Children With Super-Refractory Status Epilepticus: A Systematic Review and Experience in a Single UK Tertiary Centre. Front Neurol. 2021;12:643105doi: 10.3389/fneur.2021.643105.
Schoeler, N. E., Simpson, Z., Zhou, R., Pujar, S., Eltze, C., & Cross, J. H. (2021). Dietary Management of Children With Super-Refractory Status Epilepticus: A Systematic Review and Experience in a Single UK Tertiary Centre. Frontiers in neurology, 12643105. https://doi.org/10.3389/fneur.2021.643105
Schoeler, Natasha E, et al. "Dietary Management of Children With Super-Refractory Status Epilepticus: A Systematic Review and Experience in a Single UK Tertiary Centre." Frontiers in neurology vol. 12 (2021): 643105. doi: https://doi.org/10.3389/fneur.2021.643105
Schoeler NE, Simpson Z, Zhou R, Pujar S, Eltze C, Cross JH. Dietary Management of Children With Super-Refractory Status Epilepticus: A Systematic Review and Experience in a Single UK Tertiary Centre. Front Neurol. 2021 Mar 12;12:643105. doi: 10.3389/fneur.2021.643105. eCollection 2021. PMID: 33776895; PMCID: PMC7994594.
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Immune Checkpoint Blockade Augments Changes Within Oncolytic Virus-induced Cancer MHC-I Peptidome, Creating Novel Antitumor CD8 T Cell Reactivities.

Molecular & cellular proteomics : MCP

Kim Y, Konda P, Murphy JP, Paulo JA, Gygi SP, Gujar S.
PMID: 34922008
Mol Cell Proteomics. 2021 Dec 16;21(2):100182. doi: 10.1016/j.mcpro.2021.100182. Epub 2021 Dec 16.

The combination cancer immunotherapies with oncolytic virus (OV) and immune checkpoint blockade (ICB) reinstate otherwise dysfunctional antitumor CD8 T cell responses. One major mechanism that aids such reinstatement of antitumor CD8 T cells involves the availability of new class...

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Kim Y, Konda P, Murphy JP, et al. Immune Checkpoint Blockade Augments Changes Within Oncolytic Virus-induced Cancer MHC-I Peptidome, Creating Novel Antitumor CD8 T Cell Reactivities. Mol Cell Proteomics. 2021;21(2):100182doi: 10.1016/j.mcpro.2021.100182.
Kim, Y., Konda, P., Murphy, J. P., Paulo, J. A., Gygi, S. P., & Gujar, S. (2021). Immune Checkpoint Blockade Augments Changes Within Oncolytic Virus-induced Cancer MHC-I Peptidome, Creating Novel Antitumor CD8 T Cell Reactivities. Molecular & cellular proteomics : MCP, 21(2), 100182. https://doi.org/10.1016/j.mcpro.2021.100182
Kim, Youra, et al. "Immune Checkpoint Blockade Augments Changes Within Oncolytic Virus-induced Cancer MHC-I Peptidome, Creating Novel Antitumor CD8 T Cell Reactivities." Molecular & cellular proteomics : MCP vol. 21,2 (2021): 100182. doi: https://doi.org/10.1016/j.mcpro.2021.100182
Kim Y, Konda P, Murphy JP, Paulo JA, Gygi SP, Gujar S. Immune Checkpoint Blockade Augments Changes Within Oncolytic Virus-induced Cancer MHC-I Peptidome, Creating Novel Antitumor CD8 T Cell Reactivities. Mol Cell Proteomics. 2021 Dec 16;21(2):100182. doi: 10.1016/j.mcpro.2021.100182. Epub 2021 Dec 16. PMID: 34922008.
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Showing 13 to 24 of 214 entries