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Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH.

ACS medicinal chemistry letters

Xiao H, Li P, Li X, He H, Wang J, Guo F, Zhang J, Wei L, Zhang H, Shi Y, Hou L, Shen L, Chen Z, Du C, Fu S, Zhang P, Hao F, Wang P, Xu D, Liang W, Tian X, Zhang A, Cheng X, Yang L, Wang X, Zhang X, Li J, Chen S.
PMID: 29259742
ACS Med Chem Lett. 2017 Oct 31;8(12):1246-1251. doi: 10.1021/acsmedchemlett.7b00318. eCollection 2017 Dec 14.

Farnesoid X receptor (FXR) has become a particularly attractive target for the discovery of drugs for the treatment of liver and metabolic diseases. Obeticholic acid (

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Xiao H, Li P, Li X, et al. Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH. ACS Med Chem Lett. 2017;8(12):1246-1251doi: 10.1021/acsmedchemlett.7b00318.
Xiao, H., Li, P., Li, X., He, H., Wang, J., Guo, F., Zhang, J., Wei, L., Zhang, H., Shi, Y., Hou, L., Shen, L., Chen, Z., Du, C., Fu, S., Zhang, P., Hao, F., Wang, P., Xu, D., Liang, W., Tian, X., Zhang, A., Cheng, X., Yang, L., Wang, X., Zhang, X., Li, J., & Chen, S. (2017). Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH. ACS medicinal chemistry letters, 8(12), 1246-1251. https://doi.org/10.1021/acsmedchemlett.7b00318
Xiao, Hualing, et al. "Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH." ACS medicinal chemistry letters vol. 8,12 (2017): 1246-1251. doi: https://doi.org/10.1021/acsmedchemlett.7b00318
Xiao H, Li P, Li X, He H, Wang J, Guo F, Zhang J, Wei L, Zhang H, Shi Y, Hou L, Shen L, Chen Z, Du C, Fu S, Zhang P, Hao F, Wang P, Xu D, Liang W, Tian X, Zhang A, Cheng X, Yang L, Wang X, Zhang X, Li J, Chen S. Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH. ACS Med Chem Lett. 2017 Oct 31;8(12):1246-1251. doi: 10.1021/acsmedchemlett.7b00318. eCollection 2017 Dec 14. PMID: 29259742; PMCID: PMC5733277.
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PSMD7 downregulation induces apoptosis and suppresses tumorigenesis of esophageal squamous cell carcinoma .

FEBS open bio

Shi K, Zhang JZ, Zhao RL, Yang L, Guo D.
PMID: 29632807
FEBS Open Bio. 2018 Mar 07;8(4):533-543. doi: 10.1002/2211-5463.12394. eCollection 2018 Apr.

PSMD7, a 19S proteasome subunit, is overexpressed in most carcinoma cells. It forms a dimer with PSMD14 that functions in the removal of attached ubiquitin chain. However, there is little knowledge about the cellular mechanism of PSMD7 and its...

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Shi K, Zhang JZ, Zhao RL, et al. PSMD7 downregulation induces apoptosis and suppresses tumorigenesis of esophageal squamous cell carcinoma . FEBS Open Bio. 2018;8(4):533-543doi: 10.1002/2211-5463.12394.
Shi, K., Zhang, J. Z., Zhao, R. L., Yang, L., & Guo, D. (2018). PSMD7 downregulation induces apoptosis and suppresses tumorigenesis of esophageal squamous cell carcinoma . FEBS open bio, 8(4), 533-543. https://doi.org/10.1002/2211-5463.12394
Shi, Ke, et al. "PSMD7 downregulation induces apoptosis and suppresses tumorigenesis of esophageal squamous cell carcinoma ." FEBS open bio vol. 8,4 (2018): 533-543. doi: https://doi.org/10.1002/2211-5463.12394
Shi K, Zhang JZ, Zhao RL, Yang L, Guo D. PSMD7 downregulation induces apoptosis and suppresses tumorigenesis of esophageal squamous cell carcinoma . FEBS Open Bio. 2018 Mar 07;8(4):533-543. doi: 10.1002/2211-5463.12394. eCollection 2018 Apr. PMID: 29632807; PMCID: PMC5881544.
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Discrimination of Oil Slicks and Lookalikes in Polarimetric SAR Images Using CNN.

Sensors (Basel, Switzerland)

Guo H, Wu D, An J.
PMID: 28792477
Sensors (Basel). 2017 Aug 09;17(8). doi: 10.3390/s17081837.

Oil slicks and lookalikes (e.g., plant oil and oil emulsion) all appear as dark areas in polarimetric Synthetic Aperture Radar (SAR) images and are highly heterogeneous, so it is very difficult to use a single feature that can allow...

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Guo H, Wu D, An J. Discrimination of Oil Slicks and Lookalikes in Polarimetric SAR Images Using CNN. Sensors (Basel). 2017;17(8)doi: 10.3390/s17081837.
Guo, H., Wu, D., & An, J. (2017). Discrimination of Oil Slicks and Lookalikes in Polarimetric SAR Images Using CNN. Sensors (Basel, Switzerland), 17(8), . https://doi.org/10.3390/s17081837
Guo, Hao, et al. "Discrimination of Oil Slicks and Lookalikes in Polarimetric SAR Images Using CNN." Sensors (Basel, Switzerland) vol. 17,8 (2017). doi: https://doi.org/10.3390/s17081837
Guo H, Wu D, An J. Discrimination of Oil Slicks and Lookalikes in Polarimetric SAR Images Using CNN. Sensors (Basel). 2017 Aug 09;17(8). doi: 10.3390/s17081837. PMID: 28792477; PMCID: PMC5579578.
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A photochromic zinc-based coordination polymer for a Li-ion battery anode with high capacity and stable cycling stability.

Dalton transactions (Cambridge, England : 2003)

Xia SB, Li FS, Shen X, Li X, Cheng FX, Sun CK, Guo H, Liu JJ.
PMID: 30179244
Dalton Trans. 2018 Oct 07;47(37):13222-13228. doi: 10.1039/c8dt02930j. Epub 2018 Sep 04.

Rechargeable Li-ion batteries (LIBs) are currently the dominant power source for electric vehicles and portable electronic devices, and for small-scale stationary energy storage. However, one bottleneck of the anode materials for LIBs is the poor cycling performance caused by...

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Xia SB, Li FS, Shen X, et al. A photochromic zinc-based coordination polymer for a Li-ion battery anode with high capacity and stable cycling stability. Dalton Trans. 2018;47(37):13222-13228doi: 10.1039/c8dt02930j.
Xia, S. B., Li, F. S., Shen, X., Li, X., Cheng, F. X., Sun, C. K., Guo, H., & Liu, J. J. (2018). A photochromic zinc-based coordination polymer for a Li-ion battery anode with high capacity and stable cycling stability. Dalton transactions (Cambridge, England : 2003), 47(37), 13222-13228. https://doi.org/10.1039/c8dt02930j
Xia, Shu-Biao, et al. "A photochromic zinc-based coordination polymer for a Li-ion battery anode with high capacity and stable cycling stability." Dalton transactions (Cambridge, England : 2003) vol. 47,37 (2018): 13222-13228. doi: https://doi.org/10.1039/c8dt02930j
Xia SB, Li FS, Shen X, Li X, Cheng FX, Sun CK, Guo H, Liu JJ. A photochromic zinc-based coordination polymer for a Li-ion battery anode with high capacity and stable cycling stability. Dalton Trans. 2018 Oct 07;47(37):13222-13228. doi: 10.1039/c8dt02930j. Epub 2018 Sep 04. PMID: 30179244.
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Evaluation of ITS2 for intraspecific identification of .

Biotechnology reports (Amsterdam, Netherlands)

Li Q, Xu J, Han L, Gao C, Lu J, Du G, Sun X.
PMID: 28765814
Biotechnol Rep (Amst). 2017 Jul 08;15:101-106. doi: 10.1016/j.btre.2017.07.003. eCollection 2017 Sep.

Herbaceous peony (

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Li Q, Xu J, Han L, et al. Evaluation of ITS2 for intraspecific identification of . Biotechnol Rep (Amst). 2017;15:101-106doi: 10.1016/j.btre.2017.07.003.
Li, Q., Xu, J., Han, L., Gao, C., Lu, J., Du, G., & Sun, X. (2017). Evaluation of ITS2 for intraspecific identification of . Biotechnology reports (Amsterdam, Netherlands), 15101-106. https://doi.org/10.1016/j.btre.2017.07.003
Li, Qian, et al. "Evaluation of ITS2 for intraspecific identification of ." Biotechnology reports (Amsterdam, Netherlands) vol. 15 (2017): 101-106. doi: https://doi.org/10.1016/j.btre.2017.07.003
Li Q, Xu J, Han L, Gao C, Lu J, Du G, Sun X. Evaluation of ITS2 for intraspecific identification of . Biotechnol Rep (Amst). 2017 Jul 08;15:101-106. doi: 10.1016/j.btre.2017.07.003. eCollection 2017 Sep. PMID: 28765814; PMCID: PMC5526438.
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Alginate and polyethyleneimine dually mediated synthesis of nanosilver-containing composites for efficient p-nitrophenol reduction.

Carbohydrate polymers

Gao C, An Q, Xiao Z, Zhai S, Zhai B, Shi Z.
PMID: 29254031
Carbohydr Polym. 2018 Feb 01;181:744-751. doi: 10.1016/j.carbpol.2017.11.083. Epub 2017 Nov 28.

Three-dimensional silver/polyethyleneimine/alginate hydrogel beads have been prepared successfully via a facile and simple one-pot assembly method, which can be used efficiently in catalytic hydrogenation reaction of p-nitrophenol under batch and fixed-bed experiment. Polyethyleneimine is used to reduce and limit...

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Gao C, An Q, Xiao Z, et al. Alginate and polyethyleneimine dually mediated synthesis of nanosilver-containing composites for efficient p-nitrophenol reduction. Carbohydr Polym. 2017;181:744-751doi: 10.1016/j.carbpol.2017.11.083.
Gao, C., An, Q., Xiao, Z., Zhai, S., Zhai, B., & Shi, Z. (2018). Alginate and polyethyleneimine dually mediated synthesis of nanosilver-containing composites for efficient p-nitrophenol reduction. Carbohydrate polymers, 181744-751. https://doi.org/10.1016/j.carbpol.2017.11.083
Gao, Ce, et al. "Alginate and polyethyleneimine dually mediated synthesis of nanosilver-containing composites for efficient p-nitrophenol reduction." Carbohydrate polymers vol. 181 (2018): 744-751. doi: https://doi.org/10.1016/j.carbpol.2017.11.083
Gao C, An Q, Xiao Z, Zhai S, Zhai B, Shi Z. Alginate and polyethyleneimine dually mediated synthesis of nanosilver-containing composites for efficient p-nitrophenol reduction. Carbohydr Polym. 2018 Feb 01;181:744-751. doi: 10.1016/j.carbpol.2017.11.083. Epub 2017 Nov 28. PMID: 29254031.
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Long non-coding RNA AFAP1-AS1 is a novel biomarker in various cancers: a systematic review and meta-analysis based on the literature and GEO datasets.

Oncotarget

Wang Y, Mo Y, Yang X, Zhou R, Wu Z, He Y, Yang X, Zhong Y, Du Y, Zhou H, Li X, Li Y, Li G, Zeng Z, Guo C, Xiong W.
PMID: 29254250
Oncotarget. 2017 Oct 11;8(60):102346-102360. doi: 10.18632/oncotarget.21830. eCollection 2017 Nov 24.

BACKGROUND: Growing evidence indicates that AFAP1-AS1 plays an important role in various cancers, suggesting that it might be a potential cancer biomarker.MATERIALS AND METHODS: A meta-analysis was performed using microarray data obtained via the Affymetrix Human Genome U133 Plus...

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Wang Y, Mo Y, Yang X, et al. Long non-coding RNA AFAP1-AS1 is a novel biomarker in various cancers: a systematic review and meta-analysis based on the literature and GEO datasets. Oncotarget. 2017;8(60):102346-102360doi: 10.18632/oncotarget.21830.
Wang, Y., Mo, Y., Yang, X., Zhou, R., Wu, Z., He, Y., Yang, X., Zhong, Y., Du, Y., Zhou, H., Li, X., Li, Y., Li, G., Zeng, Z., Guo, C., & Xiong, W. (2017). Long non-coding RNA AFAP1-AS1 is a novel biomarker in various cancers: a systematic review and meta-analysis based on the literature and GEO datasets. Oncotarget, 8(60), 102346-102360. https://doi.org/10.18632/oncotarget.21830
Wang, Yumin, et al. "Long non-coding RNA AFAP1-AS1 is a novel biomarker in various cancers: a systematic review and meta-analysis based on the literature and GEO datasets." Oncotarget vol. 8,60 (2017): 102346-102360. doi: https://doi.org/10.18632/oncotarget.21830
Wang Y, Mo Y, Yang X, Zhou R, Wu Z, He Y, Yang X, Zhong Y, Du Y, Zhou H, Li X, Li Y, Li G, Zeng Z, Guo C, Xiong W. Long non-coding RNA AFAP1-AS1 is a novel biomarker in various cancers: a systematic review and meta-analysis based on the literature and GEO datasets. Oncotarget. 2017 Oct 11;8(60):102346-102360. doi: 10.18632/oncotarget.21830. eCollection 2017 Nov 24. PMID: 29254250; PMCID: PMC5731960.
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A novel organ preservation solution with efficient clearance of red blood cells improves kidney transplantation in a canine model.

Cell & bioscience

Wang S, Gumpper K, Tan T, Luo X, Guo H, Ming C, Jiang H, Fang J, Du G, Zhu H, Ma J, Chen Z, Gong N.
PMID: 29651333
Cell Biosci. 2018 Apr 10;8:28. doi: 10.1186/s13578-018-0226-2. eCollection 2018.

Organ preservation solutions are designed to minimize organ damage during transplantation. A novel preservation solution, WMO-II, was developed to have a low viscosity and to improve microvasculature perfusion for kidneys. In an autologous canine transplantation model, kidney function and...

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Wang S, Gumpper K, Tan T, et al. A novel organ preservation solution with efficient clearance of red blood cells improves kidney transplantation in a canine model. Cell Biosci. 2018;8:28doi: 10.1186/s13578-018-0226-2.
Wang, S., Gumpper, K., Tan, T., Luo, X., Guo, H., Ming, C., Jiang, H., Fang, J., Du, G., Zhu, H., Ma, J., Chen, Z., & Gong, N. (2018). A novel organ preservation solution with efficient clearance of red blood cells improves kidney transplantation in a canine model. Cell & bioscience, 828. https://doi.org/10.1186/s13578-018-0226-2
Wang, Sheng, et al. "A novel organ preservation solution with efficient clearance of red blood cells improves kidney transplantation in a canine model." Cell & bioscience vol. 8 (2018): 28. doi: https://doi.org/10.1186/s13578-018-0226-2
Wang S, Gumpper K, Tan T, Luo X, Guo H, Ming C, Jiang H, Fang J, Du G, Zhu H, Ma J, Chen Z, Gong N. A novel organ preservation solution with efficient clearance of red blood cells improves kidney transplantation in a canine model. Cell Biosci. 2018 Apr 10;8:28. doi: 10.1186/s13578-018-0226-2. eCollection 2018. PMID: 29651333; PMCID: PMC5894212.
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Minimal motor for powering particle motion from spin imbalance.

Physical review. E

Bissbort U, Teo C, Guo C, Casati G, Benenti G, Poletti D.
PMID: 28709312
Phys Rev E. 2017 Jun;95(6):062143. doi: 10.1103/PhysRevE.95.062143. Epub 2017 Jun 30.

We introduce a minimalistic quantum motor for coupled energy and particle transport. The system is composed of two spins, each coupled to a different bath and to a particle which can move on a ring consisting of three sites....

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Bissbort U, Teo C, Guo C, et al. Minimal motor for powering particle motion from spin imbalance. Phys Rev E. 2017;95(6):062143doi: 10.1103/PhysRevE.95.062143.
Bissbort, U., Teo, C., Guo, C., Casati, G., Benenti, G., & Poletti, D. (2017). Minimal motor for powering particle motion from spin imbalance. Physical review. E, 95(6), 062143. https://doi.org/10.1103/PhysRevE.95.062143
Bissbort, Ulf, et al. "Minimal motor for powering particle motion from spin imbalance." Physical review. E vol. 95,6 (2017): 062143. doi: https://doi.org/10.1103/PhysRevE.95.062143
Bissbort U, Teo C, Guo C, Casati G, Benenti G, Poletti D. Minimal motor for powering particle motion from spin imbalance. Phys Rev E. 2017 Jun;95(6):062143. doi: 10.1103/PhysRevE.95.062143. Epub 2017 Jun 30. PMID: 28709312.
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A Faraday laser lasing on Rb 1529 nm transition.

Scientific reports

Chang P, Peng H, Zhang S, Chen Z, Luo B, Chen J, Guo H.
PMID: 28827670
Sci Rep. 2017 Aug 21;7(1):8995. doi: 10.1038/s41598-017-09501-w.

We present the design and performance characterization of a Faraday laser directly lasing on the Rb 1529 nm transition (Rb, 5P

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Chang P, Peng H, Zhang S, et al. A Faraday laser lasing on Rb 1529 nm transition. Sci Rep. 2017;7(1):8995doi: 10.1038/s41598-017-09501-w.
Chang, P., Peng, H., Zhang, S., Chen, Z., Luo, B., Chen, J., & Guo, H. (2017). A Faraday laser lasing on Rb 1529 nm transition. Scientific reports, 7(1), 8995. https://doi.org/10.1038/s41598-017-09501-w
Chang, Pengyuan, et al. "A Faraday laser lasing on Rb 1529 nm transition." Scientific reports vol. 7,1 (2017): 8995. doi: https://doi.org/10.1038/s41598-017-09501-w
Chang P, Peng H, Zhang S, Chen Z, Luo B, Chen J, Guo H. A Faraday laser lasing on Rb 1529 nm transition. Sci Rep. 2017 Aug 21;7(1):8995. doi: 10.1038/s41598-017-09501-w. PMID: 28827670; PMCID: PMC5566958.
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Construction of highly efficient and stable ternary AgBr/Ag/PbBiO.

Journal of colloid and interface science

Guo H, Niu CG, Wen XJ, Zhang L, Liang C, Zhang XG, Guan DL, Tang N, Zeng GM.
PMID: 29227925
J Colloid Interface Sci. 2018 Mar 01;513:852-865. doi: 10.1016/j.jcis.2017.12.010. Epub 2017 Dec 05.

In this work, the novel ternary AgBr/Ag/PbBiO

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Guo H, Niu CG, Wen XJ, et al. Construction of highly efficient and stable ternary AgBr/Ag/PbBiO. J Colloid Interface Sci. 2017;513:852-865doi: 10.1016/j.jcis.2017.12.010.
Guo, H., Niu, C. G., Wen, X. J., Zhang, L., Liang, C., Zhang, X. G., Guan, D. L., Tang, N., & Zeng, G. M. (2018). Construction of highly efficient and stable ternary AgBr/Ag/PbBiO. Journal of colloid and interface science, 513852-865. https://doi.org/10.1016/j.jcis.2017.12.010
Guo, Hai, et al. "Construction of highly efficient and stable ternary AgBr/Ag/PbBiO." Journal of colloid and interface science vol. 513 (2018): 852-865. doi: https://doi.org/10.1016/j.jcis.2017.12.010
Guo H, Niu CG, Wen XJ, Zhang L, Liang C, Zhang XG, Guan DL, Tang N, Zeng GM. Construction of highly efficient and stable ternary AgBr/Ag/PbBiO. J Colloid Interface Sci. 2018 Mar 01;513:852-865. doi: 10.1016/j.jcis.2017.12.010. Epub 2017 Dec 05. PMID: 29227925.
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Triterpenoid Saponins from the Seeds of Aesculus chinensis and Their Cytotoxicities.

Natural products and bioprospecting

Cheng JT, Chen ST, Guo C, Jiao MJ, Cui WJ, Wang SH, Deng Z, Chen C, Chen S, Zhang J, Liu A.
PMID: 29285602
Nat Prod Bioprospect. 2018 Feb;8(1):47-56. doi: 10.1007/s13659-017-0148-4. Epub 2017 Dec 29.

Six new triterpenoid saponins, aesculusosides A-F (1-6), together with 19 known ones, were isolated from the seeds of Aesculus chinensis. The new structures were elucidated through extensive spectroscopic analyses and by comparison with previously reported data. Some of the...

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Cheng JT, Chen ST, Guo C, et al. Triterpenoid Saponins from the Seeds of Aesculus chinensis and Their Cytotoxicities. Nat Prod Bioprospect. 2017;8(1):47-56doi: 10.1007/s13659-017-0148-4.
Cheng, J. T., Chen, S. T., Guo, C., Jiao, M. J., Cui, W. J., Wang, S. H., Deng, Z., Chen, C., Chen, S., Zhang, J., & Liu, A. (2018). Triterpenoid Saponins from the Seeds of Aesculus chinensis and Their Cytotoxicities. Natural products and bioprospecting, 8(1), 47-56. https://doi.org/10.1007/s13659-017-0148-4
Cheng, Jin-Tang, et al. "Triterpenoid Saponins from the Seeds of Aesculus chinensis and Their Cytotoxicities." Natural products and bioprospecting vol. 8,1 (2018): 47-56. doi: https://doi.org/10.1007/s13659-017-0148-4
Cheng JT, Chen ST, Guo C, Jiao MJ, Cui WJ, Wang SH, Deng Z, Chen C, Chen S, Zhang J, Liu A. Triterpenoid Saponins from the Seeds of Aesculus chinensis and Their Cytotoxicities. Nat Prod Bioprospect. 2018 Feb;8(1):47-56. doi: 10.1007/s13659-017-0148-4. Epub 2017 Dec 29. PMID: 29285602; PMCID: PMC5803144.
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Showing 9985 to 9996 of 16612 entries