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Showing 25 to 36 of 249 entries
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Atrial GIRK Channels Mediate the Effects of Vagus Nerve Stimulation on Heart Rate Dynamics and Arrhythmogenesis.

Frontiers in physiology

Lee SW, Anderson A, Guzman PA, Nakano A, Tolkacheva EG, Wickman K.
PMID: 30072916
Front Physiol. 2018 Jul 19;9:943. doi: 10.3389/fphys.2018.00943. eCollection 2018.

Diminished parasympathetic influence is central to the pathogenesis of cardiovascular diseases, including heart failure and hypertension. Stimulation of the vagus nerve has shown promise in treating cardiovascular disease, prompting renewed interest in understanding the signaling pathway(s) that mediate the...

Cross Photoreaction of Glyoxylic and Pyruvic Acids in Model Aqueous Aerosol.

The journal of physical chemistry. A

Xia SS, Eugene AJ, Guzman MI.
PMID: 29999322
J Phys Chem A. 2018 Aug 09;122(31):6457-6466. doi: 10.1021/acs.jpca.8b05724. Epub 2018 Jul 25.

Aerosols of variable composition, size, and shape are associated with public health concerns as well as with light-particle interactions that play a role in the energy balance of the atmosphere. Photochemical reactions of 2-oxocarboxylic acids in the aqueous phase...

Development of anti-inflammatory peptidomimetics based on the structure of human alpha1-antitrypsin.

European journal of medicinal chemistry

Lior Y, Shtriker E, Kahremany S, Lewis EC, Gruzman A.
PMID: 34763945
Eur J Med Chem. 2022 Jan 15;228:113969. doi: 10.1016/j.ejmech.2021.113969. Epub 2021 Nov 03.

Human α1-antitrypsin (hAAT) has two distinguishing functions: anti-protease activity and regulation of the immune system. In the present study we hypothesized that those two protein functions are mediated by different structural domains on the hAAT surface. Indeed, such biologically...

Impact of human immunodeficiency virus on pulmonary vascular disease.

Global cardiology science & practice

Kumar A, Mahajan A, Salazar EA, Pruitt K, Guzman CA, Clauss MA, Almodovar S, Dhillon NK.
PMID: 34285903
Glob Cardiol Sci Pract. 2021 Jun 30;2021(2):e202112. doi: 10.21542/gcsp.2021.12. eCollection 2021 Jun 30.

With the advent of anti-retroviral therapy, non-AIDS-related comorbidities have increased in people living with HIV. Among these comorbidities, pulmonary hypertension (PH) is one of the most common causes of morbidity and mortality. Although chronic HIV-1 infection is independently associated...

Activity-Based Costing of Intensity-Modulated Proton versus Photon Therapy for Oropharyngeal Cancer.

International journal of particle therapy

Thaker NG, Boyce-Fappiano D, Ning MS, Pasalic D, Guzman A, Smith G, Holliday EB, Incalcaterra J, Garden AS, Shaitelman SF, Gunn GB, Fuller CD, Blanchard P, Feeley TW, Kaplan RS, Frank SJ.
PMID: 34285963
Int J Part Ther. 2021 Jun 25;8(1):374-382. doi: 10.14338/IJPT-20-00042.1. eCollection 2021.

PURPOSE: In value-based health care delivery, radiation oncologists need to compare empiric costs of care delivery with advanced technologies, such as intensity-modulated proton therapy (IMPT) and intensity-modulated radiation therapy (IMRT). We used time-driven activity-based costing (TDABC) to compare the...

Facets of social support are differentially predictive of mental health outcomes.

The American journal of emergency medicine

George B, Guzman A, Cohen JR, Gilmore AK, Bountress KE.
PMID: 34266729
Am J Emerg Med. 2021 Jul 02; doi: 10.1016/j.ajem.2021.06.067. Epub 2021 Jul 02.

No abstract available.

Addressing Sex Disparities in Lung Cancer Screening Eligibility: USPSTF vs PLCOm2012 Criteria.

Chest

Pasquinelli MM, Tammemägi MC, Kovitz KL, Durham ML, Deliu Z, Guzman A, Rygalski K, Liu L, Koshy M, Finn P, Feldman LE.
PMID: 34252436
Chest. 2022 Jan;161(1):248-256. doi: 10.1016/j.chest.2021.06.066. Epub 2021 Jul 09.

BACKGROUND: Lung cancer is the leading cause of cancer death in women in the United States. Prospective randomized lung screening trials suggest a greater lung cancer mortality benefit from screening women compared with men.RESEARCH QUESTION: Do the United States...

How Do Tube Diameter and Vocal Tract Configuration Affect Oral Pressure Oscillation Characteristics Caused by Bubbling During Water Resistance Therapy?.

Journal of voice : official journal of the Voice Foundation

Guzman M, Castro C, Acevedo K, Moran C, Espinoza V, Quezada C.
PMID: 32362578
J Voice. 2021 Nov;35(6):935.e1-935.e11. doi: 10.1016/j.jvoice.2020.03.004. Epub 2020 Apr 30.

PURPOSE: The present study aimed at observing the effect of tube diameter and vocal tract configuration on frequency, amplitude, and regularity of Poral oscillation caused by bubbling during water resistance therapy (WRT). A secondary objective was to examine the...

Tissue Mobilization During Double Source of Vibration Semioccluded Vocal Tract Exercises: A Neck and Face Surface Acceleration Study.

Journal of speech, language, and hearing research : JSLHR

Guzman M, Acevedo K, Castro C, Moran C, Espinoza V, Quezada C.
PMID: 34662217
J Speech Lang Hear Res. 2021 Nov 08;64(11):4124-4137. doi: 10.1044/2021_JSLHR-21-00033. Epub 2021 Oct 18.

Purpose This study primarily aimed at observing the possible tissue mobilization on facial, neck, and chest tissues caused by different double source of vibration semioccluded vocal tract exercises (DSV-SOVTEs). Another goal was to inspect the degree of self-perceived sensation...

Aqueous Photochemistry of 2-Oxocarboxylic Acids: Evidence, Mechanisms, and Atmospheric Impact.

Molecules (Basel, Switzerland)

Guzman MI, Eugene AJ.
PMID: 34500711
Molecules. 2021 Aug 31;26(17). doi: 10.3390/molecules26175278.

Atmospheric organic aerosols play a major role in climate, demanding a better understanding of their formation mechanisms by contributing multiphase chemical reactions with the participation of water. The sunlight driven aqueous photochemistry of small 2-oxocarboxylic acids is a potential...

Longitudinal multi-gene panel assessment of circulating tumor DNA revealed tumor burden and molecular characteristics along treatment course of non-small cell lung cancer.

Translational lung cancer research

Ho GYF, Wang T, Kwok HH, Rasul R, Peila R, Guzman M, Ip MSM, Lam DCL.
PMID: 33209609
Transl Lung Cancer Res. 2020 Oct;9(5):1873-1884. doi: 10.21037/tlcr-20-675.

BACKGROUND: Most studies associating circulating tumor DNA (ctDNA) with outcome in lung cancer treatment were either cross-sectional or, if longitudinal, only analyzed a limited number of genes. This study evaluated the potential of utilizing ctDNA profiled by a panel...

Level of traffic stress-based classification: A clustering approach for Bogotá, Colombia.

Transportation research. Part D, Transport and environment

Huertas JA, Palacio A, Botero M, Carvajal GA, van Laake T, Higuera-Mendieta D, Cabrales SA, Guzman LA, Sarmiento OL, Medaglia AL.
PMID: 32831580
Transp Res D Transp Environ. 2020 Aug;85:102420. doi: 10.1016/j.trd.2020.102420.

The Level of Traffic Stress (LTS) is an indicator that quantifies the stress experienced by a cyclist on the segments of a road network. We propose an LTS-based classification with two components: a clustering component and an interpretative component....

Showing 25 to 36 of 249 entries